• 1856 Citations

Research output per year

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Personal profile

Research interests

My research is focused on human Dendritic cells (DCs), a specialized family of antigen presenting cells that elicit immunity to infections and tolerance to self. DCs are composed of subsets endowed with unique functional properties. We plan to unravel the mechanisms that by which distinct human DC subsets control immunity and tolerance, and use this information to devise immune strategies for therapeutic intervention in tumors.


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Research Output

  • 1856 Citations
  • 23 Article
  • 4 Review article

Human and translational immunology in the third millennium: progress, challenges and opportunities

Galani, I. E., Klechevsky, E. & Andreakos, E., Dec 1 2019, In : Nature immunology. 20, 12, p. 1568-1573 6 p.

Research output: Contribution to journalArticle

Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis

Bambouskova, M., Gorvel, L., Lampropoulou, V., Sergushichev, A., Loginicheva, E., Johnson, K., Korenfeld, D., Mathyer, M. E., Kim, H., Huang, L. H., Duncan, D., Bregman, H., Keskin, A., Santeford, A., Apte, R. S., Sehgal, R., Johnson, B., Amarasinghe, G. K., Soares, M. P., Satoh, T. & 11 others, Akira, S., Hai, T., De Guzman Strong, C., Auclair, K., Roddy, T. P., Biller, S. A., Jovanovic, M., Klechevsky, E., Stewart, K. M., Randolph, G. J. & Artyomov, M. N., Apr 26 2018, In : Nature. 556, 7702, p. 501-504 4 p.

Research output: Contribution to journalArticle

  • 125 Scopus citations

    Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria

    Balin, S. J., Pellegrini, M., Klechevsky, E., Won, S. T., Weiss, D. I., Choi, A. W., Hakimian, J., Lu, J., Ochoa, M. T., Bloom, B. R., Lanier, L. L., Stenger, S. & Modlin, R. L., 2018, In : Science immunology. 3, 26, eaat7668.

    Research output: Contribution to journalArticle

  • 13 Scopus citations

    A type of human skin dendritic cell marked by CD5 is associated with the development of inflammatory skin disease

    Korenfeld, D., Gorvel, L., Munk, A., Man, J., Schaffer, A., Tung, T., Mann, C. & Klechevsky, E., Sep 21 2017, In : JCI Insight. 2, 18

    Research output: Contribution to journalArticle

    Open Access
  • 14 Scopus citations

    Dendritic cell-derived IL-32α: A novel inhibitory cytokine of nk cell function

    Gorvel, L., Korenfeld, D., Tung, T. & Klechevsky, E., Aug 15 2017, In : Journal of Immunology. 199, 4, p. 1290-1300 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • 9 Scopus citations