Research output per year
Research output per year
Personal profile
Research interests
My research is focused on human Dendritic cells (DCs), a specialized family of antigen presenting cells that elicit immunity to infections and tolerance to self. DCs are composed of subsets endowed with unique functional properties. We plan to unravel the mechanisms that by which distinct human DC subsets control immunity and tolerance, and use this information to devise immune strategies for therapeutic intervention in tumors.
Keywords
- COVID-19
Available to Mentor:
- PhD/MSTP Students
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TREM2 macrophages induced by human lipids drive inflammation in acne lesions
Do, T. H., Ma, F., Andrade, P. R., Teles, R., de Andrade Silva, B. J., Hu, C., Espinoza, A., Hsu, J. E., Cho, C. S., Kim, M., Xi, J., Xing, X., Plazyo, O., Tsoi, L. C., Cheng, C., Kim, J., Bryson, B. D., O’Neill, A. M., Colonna, M., Gudjonsson, J. E., & 6 others, Jul 2022, In: Science immunology. 7, 73, eabo2787.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Identification of Genes Encoding Antimicrobial Proteins in Langerhans Cells
Oulee, A., Ma, F., Teles, R. M. B., de Andrade Silva, B. J., Pellegrini, M., Klechevsky, E., Harman, A. N., Rhodes, J. W. & Modlin, R. L., Aug 26 2021, In: Frontiers in immunology. 12, 695373.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
STAT3 Gain-of-Function Mutations Underlie Deficiency in Human Nonclassical CD16+ Monocytes and CD141+ Dendritic Cells
Korenfeld, D., Roussak, K., Dinkel, S., Vogel, T. P., Pollack, H., Levy, J., Leiding, J. W., Milner, J., Cooper, M. & Klechevsky, E., Nov 15 2021, In: Journal of Immunology. 207, 10, p. 2423-2432 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
The cellular architecture of the antimicrobial response network in human leprosy granulomas
Ma, F., Hughes, T. K., Teles, R. M. B., Andrade, P. R., de Andrade Silva, B. J., Plazyo, O., Tsoi, L. C., Do, T., Wadsworth, M. H., Oulee, A., Ochoa, M. T., Sarno, E. N., Luisa Iruela-Arispe, M., Klechevsky, E., Bryson, B., Shalek, A. K., Bloom, B. R., Gudjonsson, J. E., Pellegrini, M. & Modlin, R. L., Jul 2021, In: Nature immunology. 22, 7, p. 839-850 12 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Human and translational immunology in the third millennium: progress, challenges and opportunities
Galani, I. E., Klechevsky, E. & Andreakos, E., Dec 1 2019, In: Nature immunology. 20, 12, p. 1568-1573 6 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations