If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Molecular mechanisms of neurodegeneration, with a special interest in oxidative stress; role of circadian clock genes in the regulation of brain oxidative stress, bioenergetics, and neurodegeneration; how proteins associated with neurodegenerative disease, such as Apolipoprotein E, modulate oxidative stress responses in the brain;  phenotypic and biochemical similarities between autosomal dominant (familial) and sporadic Alzheimer’s Disease, as well as to employ mass spectrometry and PET-based amyloid imaging techniques to elucidate the relationship between brain amyloid deposition, neuronal oxidative damage, and dementia in living patients

Areas of Clinical Interest

Cognitive disorders, Alzheimer's Disease, age-related neurodegenerative diseases

Fingerprint Dive into the research topics where Erik Musiek is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

Circadian regulation of astrocyte function: implications for Alzheimer’s disease

McKee, C. A., Lananna, B. V. & Musiek, E. S., Mar 1 2020, In : Cellular and Molecular Life Sciences. 77, 6, p. 1049-1058 10 p.

Research output: Contribution to journalReview article

  • 2 Scopus citations

    Evaluating Circadian Dysfunction in Mouse Models of Alzheimer’s Disease: Where Do We Stand?

    Sheehan, P. W. & Musiek, E. S., Jul 7 2020, In : Frontiers in Neuroscience. 14, 703.

    Research output: Contribution to journalReview article

    Open Access
  • Impact of circadian and diurnal rhythms on cellular metabolic function and neurodegenerative diseases

    Smith, S. K. & Musiek, E. S., 2020, International Review of Neurobiology. Söderbom, G., Esterline, R., Oscarsson, J. & Mattson, M. P. (eds.). Academic Press Inc., p. 393-412 20 p. (International Review of Neurobiology; vol. 154).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer’s disease

    Lee, J., Kim, D. E., Griffin, P., Sheehan, P. W., Kim, D. H., Musiek, E. S. & Yoon, S. Y., Feb 1 2020, In : Aging Cell. 19, 2, e13078.

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations

    The wrinkling of time: Aging, inflammation, oxidative stress, and the circadian clock in neurodegeneration

    Lananna, B. V. & Musiek, E. S., Jun 2020, In : Neurobiology of Disease. 139, 104832.

    Research output: Contribution to journalReview article

    Open Access
  • 5 Scopus citations