Our laboratory studies the cellular and molecular bases for circadian rhythms in mammals. We seek to understand the roles of defined brain regions and classes of neurons and glia in the generation and coordination of circadian rhythms in physiology and behavior. Among our objectives, we aim to identify pacemaking cells, the mechanisms that synchronize their activities to each other, and the the signals they use to communicate time-of-day information to the rest of the brain and body. We take advantage of long-term, real-time recording technologies including multimicroelectrode arrays to monitor neuronal firing patterns, bioluminescence imaging of gene expression, and novel behavioral assays. Some of our findings may have relevance to causes of and treatments for mood disorders and pediatric brain cancers.

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The Herzog lab supports researchers at all stages of training from a variety of backgrounds. We recognize the value in diverse perspectives in science, education and friendship. We are actively involved in promoting this perspective with our community through programs like WU ENDURE and certified mentor training.