Personal profile
Research interests
The Neuroskeletal Biology Laboratory (NSBL, Scheller Lab) was founded in 2016 and is part of the Musculoskeletal Research Center (MRC) and Division of Bone and Mineral Diseases at Washington University. The laboratory consists of a mix of technicians, graduate students, postdoctoral trainees, clinical fellows and undergraduate researchers. Our laboratory synthesizes concepts from cell biology, physiology, and bioengineering to study the relationships between the nervous system and the skeleton. We have a directed interest in understanding how neural signals contribute to skeletal and metabolic homeostasis, and how perturbations to this system contribute to bone loss, fracture risk and impaired healing in diseases such as diabetes and cachexia. For more information about our work and our members, please see our lab website.
Clinical interests
Our basic research models are aligned with our clinical studies in the areas of diabetes, metabolism, and bone health.
Mentoring
We welcome lab members from all backgrounds regardless of age, race, color, religion, gender identity or expression, sexual orientation, disability, or nationality. We are committed to using our diversity to promote innovation, collaboration, and success. The Scheller Lab has an open mentoring style that is modified based on the needs of the individual trainees and the evolution of these needs during the training period. This ranges from day-to-day contact via our open door policy and virtual tools to formal bi-weekly meetings, in addition to our regular lab meetings and event. We look forward to working with you to achieve your goals.
Available to Mentor:
- PhD Students
- Undergraduate Students
- Post-Baccalaureate Students
- Health Professions (Medical, OT, PT, Dental, Audiology, etc.) Students
- Postdocs
- Residents and Fellows
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
A catecholamine-independent pathway controlling adaptive adipocyte lipolysis
Zhang, X., Panicker, S. S., Bollinger, J. M., Majumdar, A., Kheireddine, R., Dabill, L. F., Kim, C., Kleiboeker, B., Zhang, F., Chen, Y., Magee, K. L., Learman, B. S., Kepecs, A., Meyer, G. A., Liu, J., Thomas, S. A., Lodhi, I. J., MacDougald, O. A. & Scheller, E. L., 2026, (Accepted/In press) In: Nature Metabolism.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
The effect of increased weight loading on body weight is partly dependent on Piezo1 in osteoblast-lineage cells and TrkA signaling
Hägg, D., Li, L., Beeve, A. T., Scheller, E. L., Bellman, J., Anesten, F., Zlatkovic, J., Gasull, A. D., Font-Gironès, F., Movérare-Skrtic, S., Jansson, J. O. & Ohlsson, C., 2026, In: Scientific reports. 16, 1, 7162.Research output: Contribution to journal › Article › peer-review
Open Access -
Adolescent Girls with Type 1 Diabetes Develop Changes in Bone Prior to Evidence of Clinical Neuropathy
Shen, I., Usala, R. L., Mohseni, M., Bouxsein, M. L., Mitchell, D. M. & Scheller, E. L., May 1 2025, In: Journal of Clinical Endocrinology and Metabolism. 110, 5, p. e1555-e1565Research output: Contribution to journal › Article › peer-review
Open Access -
A novel workflow for 3D imaging and spatial analysis of nerves in bone
Horenberg, A. L., Zeng, E. Z., Ren, Y., Sinha, T., Uyanwatte, E., Matthews, M., Scheller, E. L., Lewis, K. J., Pathak, A. P. & Grayson, W. L., Dec 2025, In: Bone Reports. 27, 101881.Research output: Contribution to journal › Article › peer-review
Open Access -
Six Drivers of Aging Identified Among Genes Differentially Expressed With Age
Coler-Reilly, A., Pincus, Z., Scheller, E. L. & Civitelli, R., Nov 2025, In: Aging Cell. 24, 11, e70225.Research output: Contribution to journal › Article › peer-review
Open Access