Personal profile
Research interests
Eric Lenze, M.D., is a geriatric psychiatrist and Professor in the Department of Psychiatry at Washington University School of Medicine. Dr. Lenze' research focus is treatment of anxiety disorders and depression in elderly persons. He has received NIMH grants to examine the treatment of depression in medically ill elderly, pharmacotherapy of late-life Generalized Anxiety Disorder, and genetic predictors of late-life depression in the context of medical illness.
Clinical interests
Treating persons aged 60 years and older with emotional problems including anxiety disorders and depression.
Keywords
- COVID-19
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Collaborations and top research areas from the last five years
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A Novel Polygenic Risk Score Indexing Somatostatin-Expressing Inhibitory Neurons Predicts Somatostatin-Expressing Cell Proportions and Severity of Symptoms in Late-Life Depression
Dos Santos, F. C., Zhou, X., Clifford, K. P., Segura, A. G., Syeda, A. S., Felsky, D., Lenze, E. J., Mulsant, B. H., Tripathy, S., Sibille, E. & Nikolova, Y. S., May 2026, In: Biological Psychiatry Global Open Science. 6, 3, 100685.Research output: Contribution to journal › Article › peer-review
Open Access -
Biological Aging Acceleration in Major Depressive Disorder: A Multi-Omics Analysis
Diniz, B. S., Zhao, S., Drouard, G., Vuoksimaa, E., Ollikainen, M., Lenze, E. J., Xu, M., Fortinsky, R. H., Kuchel, G. A., Kaprio, J. & Kuo, C. L., Jan 2026, In: Aging Cell. 25, 1, e70310.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Correction: Pharmacotherapy of major depressive disorder in older adults: from an evidence-informed stepwise algorithm to precision medicine (Neuropsychopharmacology, (2026), 10.1038/s41386-026-02338-w)
Lenze, E. J., Karp, J. F., Gebara, M. A., Nicol, G. E. & Mulsant, B. H., 2026, (Accepted/In press) In: Neuropsychopharmacology.Research output: Contribution to journal › Comment/debate
Open Access -
Designing a Culturally Adapted Perioperative Mental Health Intervention for Older Black Male Surgical Patients: A Community-Based Participatory Study
Mehta, D., Holzer, K. J., Banks, D. E., Lenze, E. J. & Abraham, J., Mar 2026, In: American Journal of Geriatric Psychiatry. 34, 3, p. 323-336 14 p.Research output: Contribution to journal › Article › peer-review
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Pharmacogenetic influence on bupropion bioactivation and clinical outcomes in major depressive disorder
Kharasch, E. D. & Lenze, E. J., Mar 2026, In: Journal of Pharmacology and Experimental Therapeutics. 393, 3, 103818.Research output: Contribution to journal › Article › peer-review