Emma Johnson

2024

Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations

Paul, S. E., Baranger, D. A. A., Johnson, E., Jackson, J. J., Gorelik, A. J., Miller, A. P., Hatoum, A. S., Thompson, W. K., Strube, M., Dick, D. M., Kamarajan, C., Kramer, J. R., Plawecki, M. H., Chan, G., Anokhin, A. P., Chorlian, D. B., Kinreich, S., Meyers, J. L., Porjesz, B. & Edenberg, H. J. & 3 others, Agrawal, A., Bucholz, K. K. & Bogdan, R., 2024, (Accepted/In press) In: Psychological medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

Associations between alcohol use disorder polygenic score and remission in participants from high-risk families and the Indiana Biobank

Lai, D., Kuo, S. I. C., Wetherill, L., Aliev, F., Zhang, M., Marco, A., Schwantes-An, T. H., Dick, D., Francis, M. W., Johnson, E. C., Kamarajan, C., Kinreich, S., Kuperman, S., Meyers, J., Nurnberger, J. I., Liu, Y., Edenberg, H. J., Porjesz, B., Agrawal, A. & Foroud, T. & 4 others, Schuckit, M., Plawecki, M. H., Bucholz, K. K. & McCutcheon, V. V., Feb 2024, In: Alcohol: Clinical and Experimental Research. 48, 2, p. 283-294 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Characteristics of women concordant and discordant for urine drug screens for cannabis exposure and self-reported cannabis use during pregnancy

Bogdan, R., Leverett, S. D., Constantino-Petit, A. M., Lashley-Simms, N., Liss, D. B., Johnson, E. C., Lenze, S. N., Lean, R. E., Smyser, T. A., Carter, E. B., Smyser, C. D., Rogers, C. E. & Agrawal, A., May 2024, In: Neurotoxicology and Teratology. 103, 107351.

Research output: Contribution to journal › Article › peer-review

Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes

Penn Medicine BioBank, PsycheMERGE Substance Use Disorder Workgroup & Million Veteran Program, Jun 2024, In: Nature Human Behaviour. 8, 6, p. 1177-1193 17 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders

Koller, D., Friligkou, E., Stiltner, B., Pathak, G. A., Løkhammer, S., Levey, D. F., Zhou, H., Hatoum, A. S., Deak, J. D., Kember, R. L., Treur, J. L., Kranzler, H. R., Johnson, E. C., Stein, M. B., Gelernter, J. & Polimanti, R., Jul 2024, In: Molecular Psychiatry. 29, 7, p. 2021-2030 10 p.

Research output: Contribution to journal › Article › peer-review

2023

A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study

Gorelik, A. J., Paul, S. E., Karcher, N. R., Johnson, E. C., Nagella, I., Blaydon, L., Modi, H., Hansen, I. S., Colbert, S. M. C., Baranger, D. A. A., Norton, S. A., Spears, I., Gordon, B., Zhang, W., Hill, P. L., Oltmanns, T. F., Bijsterbosch, J. D., Agrawal, A., Hatoum, A. S. & Bogdan, R., May 2023, In: Behavior genetics. 53, 3, p. 249-264 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

A second update on mapping the human genetic architecture of COVID-19

Admin team lead, Admin team member, Analysis team lead, Analysis team member, Data collection lead, Data collection member, Manuscript analysis team lead, Manuscript analysis team members: Mendelian randomization, Manuscript analysis team members: methods development, Manuscript analysis team members: phenome-wide association study, Manuscript analysis team members: principal component projection, gene prioritization, Project management lead, Scientific communication lead, Scientific communication member, Writing group lead, Writing group member, 23andMe, Adolescent brain and cognitive development study, Analysis group & Armenia_Covid-19hg & 49 others, Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome, Avon Longitudinal Study of Parents and Children (ALSPAC), BelCovid, Biobanque Quebec COVID19, BioVU, Bonn Study of COVID-19 Genetics, CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank, Colorado Center for Personalized Medicine—CCPM, COMRI/Virology Study, Covid19 Ioannina Biobank, COVID19-Host(a)ge, Covid19hg-CL, Danish COVID-19 Genomic Consortium, Egypt hgCOVID hub, EraCORE, FinnGen, French hgCOVID, GCAT. Genomes For Life, Genes & Health, Genetic influences on severity of COVID-19 illness in Korea, GenOMICC, Genotek COVID-19 study, Helix Exome+ COVID-19 Phenotypes, Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population, Host Genetics in COVID Cohorts of Mixed ancestry from Mexico, Japan Coronavirus Taskforce, Japan NCGM-COVID19, Jordan COVID-19 Host Genomics Initiative (JCHGI), Leadership, Lung eQTL Consortium, Mass General Brigham—Host Vulnerability to COVID-19, MexGen-COVID, Pa-COVID-19, Project management group, Project management support, Qatar Genome Program, SARS-CoV-2 and Host Genome sequencing, Scientific communication group, Search for Genomic Markers Predicting the Severity of the response to COVID-19, Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE), The Danish Blood Donor Study, The Genetic Predisposition to severe COVID-19, Tirschenreuth Study (TiKoco), UCLA Precision Health COVID-19 Host Genomics Biobank, UK Biobank, Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study), Website development, Writing Group & The COVID-19 Host Genetics Initiative, Sep 7 2023, In: Nature. 621, 7977, p. E7-E26

Research output: Contribution to journal › Letter › peer-review

Open Access

24 Scopus citations

Associations Between Cannabis Use, Polygenic Liability for Schizophrenia, and Cannabis-related Experiences in a Sample of Cannabis Users

Johnson, E. C., Colbert, S. M. C., Jeffries, P. W., Tillman, R., Bigdeli, T. B., Karcher, N. R., Chan, G., Kuperman, S., Meyers, J. L., Nurnberger, J. I., Plawecki, M. H., Degenhardt, L., Martin, N. G., Kamarajan, C., Schuckit, M. A., Murray, R. M., Dick, D. M., Edenberg, H. J., D’Souza, D. C. & Forti, M. D. & 3 others, Porjesz, B., Nelson, E. C. & Agrawal, A., May 1 2023, In: Schizophrenia bulletin. 49, 3, p. 778-787 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Characterizing Alcohol Expectancies in the ABCD Study: Associations with Sociodemographic Factors, the Immediate Social Environment, and Genetic Propensities

Johnson, E. C., Paul, S. E., Baranger, D. A. A., Hatoum, A. S., Colbert, S. M. C., Lin, S., Wolff, R., Gorelik, A. J., Hansen, I., Karcher, N. R., Bogdan, R. & Agrawal, A., May 2023, In: Behavior genetics. 53, 3, p. 265-278 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

COVID-19 pandemic stressors are associated with reported increases in frequency of drunkenness among individuals with a history of alcohol use disorder

Meyers, J. L., McCutcheon, V. V., Horne-Osipenko, K. A., Waters, L. R., Barr, P., Chan, G., Chorlian, D. B., Johnson, E. C., Kuo, S. I. C., Kramer, J. R., Dick, D. M., Kuperman, S., Kamarajan, C., Pandey, G., Singman, D., de Viteri, S. S. S., Salvatore, J. E., Bierut, L. J., Foroud, T. & Goate, A. & 8 others, Hesselbrock, V., Nurnberger, J., Plaweck, M. H., Schuckit, M. A., Agrawal, A., Edenberg, H. J., Bucholz, K. K. & Porjesz, B., Dec 2023, In: Translational psychiatry. 13, 1, 311.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Declining autozygosity over time: An exploration in over 1 million individuals from three diverse cohorts

Colbert, S. M. C., Wendt, F. R., Pathak, G. A., Helmer, D. A., Hauser, E. R., Keller, M. C., Polimanti, R. & Johnson, E. C., Jun 1 2023, In: American journal of human genetics. 110, 6, p. 1008-1014 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Diagnostic Criteria for Identifying Individuals at High Risk of Progression From Mild or Moderate to Severe Alcohol Use Disorder

Miller, A. P., Kuo, S. I. C., Johnson, E. C., Tillman, R., Brislin, S. J., Dick, D. M., Kamarajan, C., Kinreich, S., Kramer, J., McCutcheon, V. V., Plawecki, M. H., Porjesz, B., Schuckit, M. A., Salvatore, J. E., Edenberg, H. J., Bucholz, K. K., Meyers, J. L. & Agrawal, A., Oct 2 2023, In: JAMA Network Open. p. E2337192

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders

Saenz de Viteri, S., Zhang, J., Johnson, E. C., Barr, P. B., Edenberg, H. J., Hesselbrock, V. M., Nurnberger, J. I., Pandey, A. K., Kamarajan, C., Kinreich, S., Tischfield, J. A., Plawecki, M. H., Kramer, J. R., Lai, D., Kuperman, S., Chan, G., McCutcheon, V. V., Bucholz, K. K., Porjesz, B. & Meyers, J. L., Aug 2023, In: Molecular Psychiatry. 28, 8, p. 3391-3396 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, May 6 2023, In: The Lancet. 401, 10387, p. 1499-1507 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Identifying genetic loci and phenomic associations of substance use traits: A multi-trait analysis of GWAS (MTAG) study

Xu, H., Toikumo, S., Crist, R. C., Glogowska, K., Jinwala, Z., Deak, J. D., Justice, A. C., Gelernter, J., Johnson, E. C., Kranzler, H. R. & Kember, R. L., Oct 2023, In: Addiction. 118, 10, p. 1942-1952 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder

Johnson, E. C., Kapoor, M., Hatoum, A. S., Zhou, H., Polimanti, R., Wendt, F. R., Walters, R. K., Lai, D., Kember, R. L., Hartz, S., Meyers, J. L., Peterson, R. E., Ripke, S., Bigdeli, T. B., Fanous, A. H., Pato, C. N., Pato, M. T., Goate, A. M., Kranzler, H. R. & O'Donovan, M. C. & 4 others, Walters, J. T. R., Gelernter, J., Edenberg, H. J. & Agrawal, A., Mar 7 2023, In: Psychological medicine. 53, 4, p. 1196-1204 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications

Veterans Affairs Million Veteran Program, Dec 2023, In: Nature Genetics. 55, 12, p. 2094-2103 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals

Million Veteran Program, Zhou, H., Kember, R. L., Deak, J. D., Xu, H., Toikumo, S., Yuan, K., Lind, P. A., Farajzadeh, L., Wang, L., Hatoum, A. S., Johnson, J., Lee, H., Mallard, T. T., Xu, J., Johnston, K. J. A., Johnson, E. C., Nielsen, T. T., Galimberti, M. & Dao, C. & 30 others, Levey, D. F., Overstreet, C., Byrne, E. M., Gillespie, N. A., Gordon, S., Hickie, I. B., Whitfield, J. B., Xu, K., Zhao, H., Huckins, L. M., Davis, L. K., Sanchez-Roige, S., Madden, P. A. F., Heath, A. C., Medland, S. E., Martin, N. G., Ge, T., Smoller, J. W., Hougaard, D. M., Børglum, A. D., Demontis, D., Krystal, J. H., Gaziano, J. M., Edenberg, H. J., Agrawal, A., Zhao, H., Justice, A. C., Stein, M. B., Kranzler, H. R. & Gelernter, J., Dec 2023, In: Nature medicine. 29, 12, p. 3184-3192 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study

CLARITY study investigators, Feb 1 2023, In: The Lancet Gastroenterology and Hepatology. 8, 2, p. 145-156 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Polygenic Contributions to Suicidal Thoughts and Behaviors in a Sample Ascertained for Alcohol Use Disorders

Colbert, S. M. C., Mullins, N., Chan, G., Meyers, J. L., Schulman, J., Kuperman, S., Lai, D., Nurnberger, J., Plawecki, M. H., Kamarajan, C., Anokhin, A. P., Bucholz, K. K., Hesselbrock, V., Edenberg, H. J., Kramer, J., Dick, D. M., Porjesz, B., Agrawal, A. & Johnson, E. C., Jan 18 2023, In: Complex Psychiatry. 9, 1-4, p. 11-23 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Polygenic Risk for Schizophrenia, Major Depression, and Post-traumatic Stress Disorder and Hippocampal Subregion Volumes in Middle Childhood

Pine, J. G., Paul, S. E., Johnson, E., Bogdan, R., Kandala, S. & Barch, D. M., May 2023, In: Behavior genetics. 53, 3, p. 279-291 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: The EU-GEI case-control study

Spinazzola, E., Quattrone, D., Rodriguez, V., Trotta, G., Alameda, L., Tripoli, G., Gayer-Anderson, C., Freeman, T. P., Johnson, E. C., Jongsma, H. E., Stilo, S., La Cascia, C., Ferraro, L., La Barbera, D., Lasalvia, A., Tosato, S., Tarricone, I., D'Andrea, G., Galatolo, M. & Tortelli, A. & 25 others, Tagliabue, I., Turco, M., Pompili, M., Selten, J. P., De Haan, L., Rossi Menezes, P., Del Ben, C. M., Santos, J. L., Arrojo, M., Bobes, J., Sanjuán, J., Bernardo, M., Arango, C., Kirkbride, J. B., Jones, P. B., O'Donovan, M., Rutten, B. P., Van Os, J., Morgan, C., Sham, P. C., Austin-Zimmerman, I., Li, Z., Vassos, E., Murray, R. M. & Di Forti, M., Nov 2 2023, In: Psychological medicine. 53, 15, p. 7418-7427 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

The collaborative study on the genetics of alcoholism: Genetics

Johnson, E. C., Salvatore, J. E., Lai, D., Merikangas, A. K., Nurnberger, J. I., Tischfield, J. A., Xuei, X., Kamarajan, C., Wetherill, L., Rice, J. P., Kramer, J. R., Kuperman, S., Foroud, T., Slesinger, P. A., Goate, A. M., Porjesz, B., Dick, D. M., Edenberg, H. J. & Agrawal, A., Oct 2023, In: Genes, Brain and Behavior. 22, 5, e12856.

Research output: Contribution to journal › Review article › peer-review

Open Access

9 Scopus citations

The collaborative study on the genetics of alcoholism: Sample and clinical data

COGA Collaborators, Dick, D. M., Balcke, E., McCutcheon, V., Francis, M., Kuo, S., Salvatore, J., Meyers, J., Bierut, L. J., Schuckit, M., Hesselbrock, V., Edenberg, H. J., Porjesz, B., Porjesz, B., Hesselbrock, V., Foroud, T., Agrawal, A., Dick, D., Hesselbrock, V. & Edenberg, H. J. & 53 others, Foroud, T., Liu, Y., Plawecki, M. H., Kuperman, S., Kramer, J., Porjesz, B., Meyers, J., Kamarajan, C., Pandey, A., Bierut, L., Rice, J., Bucholz, K., Agrawal, A., Schuckit, M., Tischfield, J., Dick, D., Hart, R., Salvatore, J., Almasy, L., Goate, A., Slesinger, P., Scott, D., Bauer, L., Nurnberger, J., Wetherill, L., Xuei, X., Lai, D., O'Connor, S., Chan, G., Chorlian, D. B., Zhang, J., Barr, P., Kinreich, S., Pandey, G., Mullins, N., Anokhin, A., Hartz, S., Johnson, E., McCutcheon, V., Saccone, S., Moore, J., Aliev, F., Pang, Z., Kuo, S., Merikangas, A., Chin, H., Li, T. K., Conneally, P. M., Crowe, R., Reich, W., Kuperman, S., Kramer, J. & Bucholz, K., Oct 2023, In: Genes, Brain and Behavior. 22, 5, e12860.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

The Collaborative Study on the Genetics of Alcoholism: Overview

COGA Collaborators, Agrawal, A., Brislin, S. J., Bucholz, K. K., Dick, D., Hart, R. P., Johnson, E. C., Meyers, J., Salvatore, J., Slesinger, P., Liu, Y., Plawecki, M. H., Kamarajan, C., Pandey, A., Bierut, L., Rice, J., Schuckit, M., Scott, D., Bauer, L. & Wetherill, L. & 31 others, Xuei, X., Lai, D., O'Connor, S., Chan, G., Chorlian, D. B., Zhang, J., Barr, P., Kinreich, S., Pandey, G., Mullins, N., Anokhin, A., Hartz, S., McCutcheon, V., Saccone, S., Moore, J., Aliev, F., Pang, Z., Kuo, S., Chin, H., Parsian, A., Almasy, L., Foroud, T., Goate, A., Hesselbrock, V., Kramer, J., Kuperman, S., Merikangas, A. K., Nurnberger, J. I., Tischfield, J., Edenberg, H. J. & Porjesz, B., Oct 2023, In: Genes, Brain and Behavior. 22, 5, e12864.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

The Genetically Informed Neurobiology of Addiction (GINA) model

Bogdan, R., Hatoum, A. S., Johnson, E. C. & Agrawal, A., Jan 2023, In: Nature Reviews Neuroscience. 24, 1, p. 40-57 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

2022

Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, Abani, O., Abbas, A., Abbas, F., Abbas, M., Abbasi, S., Abbass, H., Abbott, A., Abdallah, N., Abdelaziz, A., Abdelfattah, M., Abdelqader, B., Abdul, B., Abdul Rasheed, A., Abdulakeem, A., Abdul-Kadir, R., Abdullah, A., Abdulmumeen, A., Abdul-Raheem, R. & Abdulshukkoor, N. & 181 others, Abdusamad, K., Abed El Khaleq, Y., Abedalla, M., Abeer Ul Amna, A. U. A., Abernethy, K., Aboaba, A., Abo-Leyah, H., Abou-Haggar, A., Abouibrahim, M., Abraham, M., Abraham, T., Abraheem, A., Abrams, J., Abu, H. J., Abu-Arafeh, A., Abubacker, S. M., Abung, A., Aceampong, Y., Achara, A., Acharya, D., Acheampong, S., Acheson, J., Acosta, A., Acton, C., Adabie-Ankrah, J., Adam, F., Adam, M., Adamali, H., Adams, C., Adams, C., Adams, K., Adams, R., Adams, T., Adcock, K., Adebiyi, A., Adegoke, K., Adell, V., Adenwalla, S., Adesemoye, O. A., Adewunmi, E. O., Adeyemi, J., Adhikari, B., Adhikary, R., Adkins, G., Adnan, A., Aeron-Thomas, J., Affleck, D., Afnan, C., Afridi, M., Aftab, Z. A., Agarwal, M., Agbeko, R., Agbo, C., Aggarwal, S., Aghababaie, A., Ahamed Sadiq, S., Ahammed Nazeer, M. H., Ahmad, M., Ahmad, S., Ahmed, A., Ahmed, B., Ahmed, F., Ahmed, H., Ahmed, I., Ahmed, I., Ahmed, K., Ahmed, L., Ahmed, M., Ahmed, M. C., Ahmed, M. S., Ahmed, N., Ahmed, N., Ahmed, O., Ahmed, R. A., Ahmed, R., Ahmed, S., Ahmed, S., Ahmed, S., Ahmed, S., Ahmed, S. H., Ahmed Ali, R., Ahmed, S., Ahmer, S., Ail, D., Ainsworth, M., Aissa, M., Aitken, L., Ajay, B., Ajibode, A., Ajmi, A., Akhtar, N., Akhtar, N., Akili, S., Akindolie, O., Akinfenwa, Y., Akinkugbe, O., Akinpelu, I., Aktinade, O., Al Aaraj, A., Al Balushi, A., Al Dakhola, M., Al Swaifi, A., Al-Abadi, E., Aladangady, N., Alam, A., Alam, S., Al-Asadi, A., Alatzoglou, K., Albert, P., Albon, L., Alcorn, G., Alcorn, S., Aldana, A., Alderdice, D., Aldouri, R., Aldridge, J., Aldridge, N., Alegria, A., Alexander, A., Alexander, J., Alexander, P. D. G., Al-Fori, J., Alghazawi, L., Al-Hakim, B., Al-Hity, S., Ali, A., Ali, A., Ali, F. R., Ali, J., Ali, M., Ali, M., Ali, N., Ali, O., Ali, S., Ali, S., Alina, A., Aliyuda, F., Alizadeh, K., Al-Jibury, M., Al-Juboori, S., Al-Khalil, M., Alkhusheh, M., Allan, F., Allanson, A., Allcock, R., Allen, E., Allen, K., Allen, L., Allen, P., Allen, R., Allen, S., Allen, S., Allen, S., Allison, K., Allman, B., Allsop, L., Al-Moasseb, H., Al-Obaidi, M., Alomari, L., Al-Rabahi, A., Al-Ramadhani, B., Al-Saadi, Z., Alshaer, I., Al-Shahi Salman, R., Al-Shamkhani, W., Al-Sheklly, B., Altaf, S., Alvarez, M., Alzetani, M., Amamou, S., Amar, N., Ambalavanan, S., Ambler, S. J., Ambrogetti, R., Ambrose, C., Ameen, A., Amezaga, M. R., Amin, A., Amin, A., Amin, K. & Johnson, E., Jan 8 2022, In: The Lancet. 399, 10320, p. 143-151 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

212 Scopus citations

Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early Adolescence: Longitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study

Baranger, D. A. A., Paul, S. E., Colbert, S. M. C., Karcher, N. R., Johnson, E. C., Hatoum, A. S. & Bogdan, R., Dec 5 2022, In: JAMA Pediatrics. 176, 12, p. 1261-1265 5 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

20 Scopus citations

Associations between cognition and polygenic liability to substance involvement in middle childhood: Results from the ABCD study

Paul, S. E., Hatoum, A. S., Barch, D. M., Thompson, W. K., Agrawal, A., Bogdan, R. & Johnson, E. C., Mar 1 2022, In: Drug and Alcohol Dependence. 232, 109277.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

RECOVERY Collaborative Group, Jul 30 2022, In: The Lancet. 400, 10349, p. 359-368 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

178 Scopus citations

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, Feb 12 2022, In: The Lancet. 399, 10325, p. 665-676 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

245 Scopus citations

Characterisation of the genetic relationship between the domains of sleep and circadian-related behaviours with substance use phenotypes

Hatoum, A. S., Winiger, E. A., Morrison, C. L., Johnson, E. C. & Agrawal, A., Jul 2022, In: Addiction Biology. 27, 4, e13184.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Commentary on Lannoy et al. The continued value of within-family designs in addiction and psychiatric research

Colbert, S. M. C. & Johnson, E. C., Nov 2022, In: Addiction. 117, 11, p. 2953-2954 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

Erratum: Genetics of substance use disorders: a review - CORRIGENDUM (Psychological medicine (2021) 51 13 (2189-2200))

Deak, J. D. & Johnson, E. C., Mar 1 2022, In: Psychological medicine. 52, 4, p. 800 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

Evaluating risk for alcohol use disorder: Polygenic risk scores and family history

Lai, D., Johnson, E. C., Colbert, S., Pandey, G., Chan, G., Bauer, L., Francis, M. W., Hesselbrock, V., Kamarajan, C., Kramer, J., Kuang, W., Kuo, S., Kuperman, S., Liu, Y., McCutcheon, V., Pang, Z., Plawecki, M. H., Schuckit, M., Tischfield, J. & Wetherill, L. & 5 others, Zang, Y., Edenberg, H. J., Porjesz, B., Agrawal, A. & Foroud, T., Mar 2022, In: Alcoholism: Clinical and Experimental Research. 46, 3, p. 374-383 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Exploring the Relationships Between Autozygosity, Educational Attainment, and Cognitive Ability in a Contemporary, Trans-Ancestral American Sample

Colbert, S. M., Keller, M. C., Agrawal, A. & Johnson, E. C., Nov 2022, In: Behavior genetics. 52, 6, p. 315-323 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci

Deak, J. D., Zhou, H., Galimberti, M., Levey, D. F., Wendt, F. R., Sanchez-Roige, S., Hatoum, A. S., Johnson, E. C., Nunez, Y. Z., Demontis, D., Børglum, A. D., Rajagopal, V. M., Jennings, M. V., Kember, R. L., Justice, A. C., Edenberg, H. J., Agrawal, A., Polimanti, R., Kranzler, H. R. & Gelernter, J., Oct 2022, In: Molecular Psychiatry. 27, 10, p. 3970-3979 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts

Mallard, T. T., Savage, J. E., Johnson, E. C., Huang, Y., Edwards, A. C., Hottenga, J. J., Grotzinger, A. D., Gustavson, D. E., Jennings, M. V., Anokhin, A., Dick, D. M., Edenberg, H. J., Kramer, J. R., Lai, D., Meyers, J. L., Pandey, A. K., Harden, K. P., Nivard, M. G., de Geus, E. J. C. & Boomsma, D. I. & 5 others, Agrawal, A., Davis, L. K., Clarke, T. K., Palmer, A. A. & Sanchez-Roige, S., Jan 2022, In: American Journal of Psychiatry. 179, 1, p. 58-70 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

Psychotic-like Experiences and Polygenic Liability in the Adolescent Brain Cognitive Development Study

Karcher, N. R., Paul, S. E., Johnson, E. C., Hatoum, A. S., Baranger, D. A. A., Agrawal, A., Thompson, W. K., Barch, D. M. & Bogdan, R., Jan 2022, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 7, 1, p. 45-55 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates

Hatoum, A. S., Johnson, E. C., Colbert, S. M. C., Polimanti, R., Zhou, H., Walters, R. K., Gelernter, J., Edenberg, H. J., Bogdan, R. & Agrawal, A., Sep 2022, In: Neuropsychopharmacology. 47, 10, p. 1739-1745 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

2021

Associations between Prenatal Cannabis Exposure and Childhood Outcomes: Results from the ABCD Study

Paul, S. E., Hatoum, A. S., Fine, J. D., Johnson, E. C., Hansen, I., Karcher, N. R., Moreau, A. L., Bondy, E., Qu, Y., Carter, E. B., Rogers, C. E., Agrawal, A., Barch, D. M. & Bogdan, R., Jan 2021, In: JAMA psychiatry. 78, 1, p. 64-76 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

176 Scopus citations

Associations between Suicidal Thoughts and Behaviors and Genetic Liability for Cognitive Performance, Depression, and Risk-Taking in a High-Risk Sample

Johnson, E. C., Aliev, F., Meyers, J. L., Salvatore, J. E., Tillman, R., Chang, Y., Docherty, A. R., Bogdan, R., Acion, L., Chan, G., Chorlian, D. B., Kamarajan, C., Kuperman, S., Pandey, A., Plawecki, M. H., Schuckit, M., Tischfield, J., Edenberg, H. J., Bucholz, K. K. & Nurnberger, J. I. & 5 others, Porjesz, B., Hesselbrock, V., Dick, D. M., Kramer, J. R. & Agrawal, A., Aug 1 2021, In: Complex Psychiatry. 7, 1-2, p. 34-44 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Cannabis Use, Pulmonary Function, and Lung Cancer Susceptibility: A Mendelian Randomization Study

International Lung Cancer Consortium, Jul 2021, In: Journal of Thoracic Oncology. 16, 7, p. 1127-1135 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

RECOVERY Collaborative Group, May 29 2021, In: The Lancet. 397, 10289, p. 2049-2059 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

364 Scopus citations

Exploring the genetic overlap of suicide-related behaviors and substance use disorders

Colbert, S. M. C., Hatoum, A. S., Shabalin, A., Li, Q. S., Coon, H., Nelson, E. C., Agrawal, A., Docherty, A. R. & Johnson, E. C., Dec 2021, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 186, 8, p. 445-455 11 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Genes identified in rodent studies of alcohol intake are enriched for heritability of human substance use

Huggett, S. B., Johnson, E. C., Hatoum, A. S., Lai, D., Srijeyanthan, J., Bubier, J. A., Chesler, E. J., Agrawal, A., Palmer, A. A., Edenberg, H. J. & Palmer, R. H. C., Dec 2021, In: Alcoholism: Clinical and Experimental Research. 45, 12, p. 2485-2494 10 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Genetic Liability to Cannabis Use Disorder and COVID-19 Hospitalization

Hatoum, A. S., Morrison, C. L., Colbert, S. M. C., Winiger, E. A., Johnson, E. C., Agrawal, A. & Bogdan, R., Dec 2021, In: Biological Psychiatry Global Open Science. 1, 4, p. 317-323 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Genetics of substance use disorders: A review

Deak, J. D. & Johnson, E. C., Oct 21 2021, In: Psychological medicine. 51, 13, p. 2189-2200 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

64 Scopus citations

Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

Sherva, R., Zhu, C., Wetherill, L., Edenberg, H. J., Johnson, E., Degenhardt, L., Agrawal, A., Martin, N. G., Nelson, E., Kranzler, H. R., Gelernter, J. & Farrer, L. A., 2021, In: Exploration of Medicine. 2, 1, p. 60-73 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Integration of evidence across human and model organism studies: A meeting report

Palmer, R. H. C., Johnson, E. C., Won, H., Polimanti, R., Kapoor, M., Chitre, A., Bogue, M. A., Benca-Bachman, C. E., Parker, C. C., Verma, A., Reynolds, T., Ernst, J., Bray, M., Kwon, S. B., Lai, D., Quach, B. C., Gaddis, N. C., Saba, L., Chen, H. & Hawrylycz, M. & 30 others, Zhang, S., Zhou, Y., Mahaffey, S., Fischer, C., Sanchez-Roige, S., Bandrowski, A., Lu, Q., Shen, L., Philip, V., Gelernter, J., Bierut, L. J., Hancock, D. B., Edenberg, H. J., Johnson, E. O., Nestler, E. J., Barr, P. B., Prins, P., Smith, D. J., Akbarian, S., Thorgeirsson, T., Walton, D., Baker, E., Jacobson, D., Palmer, A. A., Miles, M., Chesler, E. J., Emerson, J., Agrawal, A., Martone, M. & Williams, R. W., Jul 2021, In: Genes, Brain and Behavior. 20, 6, e12738.

Research output: Contribution to journal › Review article › peer-review

Open Access

8 Scopus citations

Emma Johnson

Research output

Search results