Emily Zarbock

2025

Regulation of Type 1 Diabetes via Brown Adipocyte–Secreted Proteins and the Novel Glucagon Regulator Nidogen-2

Lee, J., Ustione, A., Wilkerson, E. M., Balakrishnan, R., Thurmond, D. C., Goldfarb, D. & Piston, D. W., Jun 2025, In: Diabetes. 74, 6, p. 907-920 14 p.

Research output: Contribution to journal › Article › peer-review

2024

TCAF1 promotes TRPV2-mediated Ca²⁺ release in response to cytosolic DNA to protect stressed replication forks

Kong, L., Cheng, C., Cheruiyot, A., Yuan, J., Yang, Y., Hwang, S., Foust, D., Tsao, N., Wilkerson, E., Mosammaparast, N., Major, M. B., Piston, D. W., Li, S. & You, Z., Dec 2024, In: Nature communications. 15, 1, 4609.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein

Mooren, O. L., Stuchell-Brereton, M. D., McConnell, P., Yan, C., Wilkerson, E. M., Goldfarb, D., Cooper, J. A., Sept, D. & Soranno, A., Dec 15 2023, In: Journal of Molecular Biology. 435, 24, 168342.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Structural basis of paralog-specific KDM2A/B nucleosome recognition

Spangler, C. J., Skrajna, A., Foley, C. A., Nguyen, A., Budziszewski, G. R., Azzam, D. N., Arteaga, E. C., Simmons, H. C., Smith, C. B., Wesley, N. A., Wilkerson, E. M., McPherson, J. M. E., Kireev, D., James, L. I., Frye, S. V., Goldfarb, D. & McGinty, R. K., May 2023, In: Nature Chemical Biology. 19, 5, p. 624-632 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC

Wamsley, N. T., Wilkerson, E. M., Guan, L., LaPak, K. M., Schrank, T. P., Holmes, B. J., Sprung, R. W., Gilmore, P. E., Gerndt, S. P., Jackson, R. S., Paniello, R. C., Pipkorn, P., Puram, S. V., Rich, J. T., Townsend, R. R., Zevallos, J. P., Zolkind, P., Le, Q. T., Goldfarb, D. & Major, M. B., 2023, In: Molecular and Cellular Proteomics. 22, 11, 100647.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

2021

Erratum: Positive Cooperativity in Substrate Binding by Human Thymidylate Synthase (Biophysical Journal (2019) 117(6) (1074–1084), (S0006349519307106), (10.1016/j.bpj.2019.08.015))

Bonin, J. P., Sapienza, P. J., Wilkerson, E., Goldfarb, D., Wang, L., Herring, L., Chen, X., Major, M. B. & Lee, A. L., Sep 21 2021, In: Biophysical Journal. 120, 18, p. 4137 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

2 Scopus citations

2020

Mass spectrometry– based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells

McDonald, I. M., Grant, G. D., East, M. P., Gilbert, T. S. K., Wilkerson, E. M., Goldfarb, D., Beri, J., Herring, L. E., Vaziri, C., Cook, J. G., Emanuele, M. J. & Graves, L. M., Feb 21 2020, In: Journal of Biological Chemistry. 295, 8, p. 2359-2374 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B'δ holoenzyme

Jong, C. J., Merrill, R. A., Wilkerson, E. M., Herring, L. E., Graves, L. M. & Strack, S., Apr 24 2020, In: Journal of Biological Chemistry. 295, 17, p. 5654-5668 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

TBK1 is a synthetic lethal target in cancer with VHL loss

Hu, L., Xie, H., Liu, X., Potjewyd, F., James, L. I., Wilkerson, E. M., Herring, L. E., Xie, L., Chen, X., Cabrera, J. C., Hong, K., Liao, C., Tan, X., Baldwin, A. S., Gong, K. & Zhang, Q., Mar 2020, In: Cancer discovery. 10, 3, p. 460-475 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

81 Scopus citations

2019

An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis

Lohman, D. C., Aydin, D., Von Bank, H. C., Smith, R. W., Linke, V., Weisenhorn, E., McDevitt, M. T., Hutchins, P., Wilkerson, E. M., Wancewicz, B., Russell, J., Stefely, M. S., Beebe, E. T., Jochem, A., Coon, J. J., Bingman, C. A., Dal Peraro, M. & Pagliarini, D. J., Feb 21 2019, In: Molecular cell. 73, 4, p. 763-774.e10

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Positive Cooperativity in Substrate Binding by Human Thymidylate Synthase

Bonin, J. P., Sapienza, P. J., Wilkerson, E., Goldfarb, D., Wang, L., Herring, L., Chen, X., Major, M. B. & Lee, A. L., Sep 17 2019, In: Biophysical Journal. 117, 6, p. 1074-1084 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Therapeutic effect of Y-27632 on tumorigenesis and cisplatin-induced peripheral sensory loss through RhoA-NF-κB

Zhu, Y., Howard, G. A., Pittman, K., Boykin, C., Herring, L. E., Wilkerson, E. M., Verbanac, K. & Lu, Q., 2019, In: Molecular Cancer Research. 17, 9, p. 1910-1919 10 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2018

Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family

Reidenbach, A. G., Kemmerer, Z. A., Aydin, D., Jochem, A., McDevitt, M. T., Hutchins, P. D., Stark, J. L., Stefely, J. A., Reddy, T., Hebert, A. S., Wilkerson, E. M., Johnson, I. E., Bingman, C. A., Markley, J. L., Coon, J. J., Dal Peraro, M. & Pagliarini, D. J., Feb 15 2018, In: Cell Chemical Biology. 25, 2, p. 154-165.e11

Research output: Contribution to journal › Article › peer-review

Open Access

58 Scopus citations

Expression of novel “LOCGEF” isoforms of ARHGEF18 in eosinophils

Turton, K. B., Wilkerson, E. M., Hebert, A. S., Fogerty, F. J., Schira, H. M., Botros, F. E., Coon, J. J. & Mosher, D. F., Jul 2018, In: Journal of Leukocyte Biology. 104, 1, p. 135-145 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2017

Proteomics of eosinophil activation

Mosher, D. F., Wilkerson, E. M., Turton, K. B., Hebert, A. S. & Coon, J. J., 2017, In: Frontiers in Medicine. 4, SEP, 159.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

2016

Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity

Stefely, J. A., Licitra, F., Laredj, L., Reidenbach, A. G., Kemmerer, Z. A., Grangeray, A., Jaeg-Ehret, T., Minogue, C. E., Ulbrich, A., Hutchins, P. D., Wilkerson, E. M., Ruan, Z., Aydin, D., Hebert, A. S., Guo, X., Freiberger, E. C., Reutenauer, L., Jochem, A., Chergova, M. & Johnson, I. E. & 18 others, Lohman, D. C., Rush, M. J. P., Kwiecien, N. W., Singh, P. K., Schlagowski, A. I., Floyd, B. J., Forsman, U., Sindelar, P. J., Westphall, M. S., Pierrel, F., Zoll, J., Dal Peraro, M., Kannan, N., Bingman, C. A., Coon, J. J., Isope, P., Puccio, H. & Pagliarini, D. J., Aug 18 2016, In: Molecular cell. 63, 4, p. 608-620 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

95 Scopus citations

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function

Floyd, B. J., Wilkerson, E. M., Veling, M. T., Minogue, C. E., Xia, C., Beebe, E. T., Wrobel, R. L., Cho, H., Kremer, L. S., Alston, C. L., Gromek, K. A., Dolan, B. K., Ulbrich, A., Stefely, J. A., Bohl, S. L., Werner, K. M., Jochem, A., Westphall, M. S., Rensvold, J. W. & Taylor, R. W. & 4 others, Prokisch, H., Kim, J. J. P., Coon, J. J. & Pagliarini, D. J., Aug 18 2016, In: Molecular cell. 63, 4, p. 621-632 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

217 Scopus citations

NeuCode Proteomics Reveals Bap1 Regulation of Metabolism

Baughman, J. M., Rose, C. M., Kolumam, G., Webster, J. D., Wilkerson, E. M., Merrill, A. E., Rhoads, T. W., Noubade, R., Katavolos, P., Lesch, J., Stapleton, D. S., Rabaglia, M. E., Schueler, K. L., Asuncion, R., Domeyer, M., Zavala-Solorio, J., Reich, M., DeVoss, J., Keller, M. P. & Attie, A. D. & 5 others, Hebert, A. S., Westphall, M. S., Coon, J. J., Kirkpatrick, D. S. & Dey, A., Jul 12 2016, In: Cell Reports. 16, 2, p. 583-595 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

59 Scopus citations

The peripheral blood eosinophil proteome

Wilkerson, E. M., Johansson, M. W., Hebert, A. S., Westphall, M. S., Mathur, S. K., Jarjour, N. N., Schwantes, E. A., Mosher, D. F. & Coon, J. J., May 6 2016, In: Journal of Proteome Research. 15, 5, p. 1524-1533 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

74 Scopus citations

2013

Differences in the regulation of K-Ras and H-Ras isoforms by monoubiquitination

Baker, R., Wilkerson, E. M., Sumita, K., Isom, D. G., Sasaki, A. T., Dohlman, H. G. & Campbell, S. L., Dec 27 2013, In: Journal of Biological Chemistry. 288, 52, p. 36856-36862 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function

Baker, R., Lewis, S. M., Sasaki, A. T., Wilkerson, E. M., Locasale, J. W., Cantley, L. C., Kuhlman, B., Dohlman, H. G. & Campbell, S. L., Jan 2013, In: Nature Structural and Molecular Biology. 20, 1, p. 46-52 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

83 Scopus citations

Emily Zarbock

Research output

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