Elizabeth Newberry

2024

Impaired Hepatic Very Low-Density Lipoprotein Secretion Promotes Tumorigenesis and Is Accelerated with Fabp1 Deletion

Newberry, E. P., Molitor, E. A., Liu, A., Chong, K., Liu, X., Alonso, C., Mato, J. M. & Davidson, N. O., Jun 2024, In: American Journal of Pathology. 194, 6, p. 958-974 17 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2023

Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development

Kulkarni, D. H., Rusconi, B., Floyd, A. N., Joyce, E. L., Talati, K. B., Kousik, H., Alleyne, D., Harris, D. L., Garnica, L., McDonough, R., Bidani, S. S., Kulkarni, H. S., Newberry, E. P., McDonald, K. G. & Newberry, R. D., 2023, In: Gut microbes. 15, 2, 2284240.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2022

Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles

Martínez-Arranz, I., Bruzzone, C., Noureddin, M., Gil-Redondo, R., Mincholé, I., Bizkarguenaga, M., Arretxe, E., Iruarrizaga-Lejarreta, M., Fernández-Ramos, D., Lopitz-Otsoa, F., Mayo, R., Embade, N., Newberry, E., Mittendorf, B., Izquierdo-Sánchez, L., Smid, V., Arnold, J., Iruzubieta, P., Pérez Castaño, Y. & Krawczyk, M. & 21 others, Marigorta, U. M., Morrison, M. C., Kleemann, R., Martín-Duce, A., Hayardeny, L., Vitek, L., Bruha, R., Aller de la Fuente, R., Crespo, J., Romero-Gomez, M., Banales, J. M., Arrese, M., Cusi, K., Bugianesi, E., Klein, S., Lu, S. C., Anstee, Q. M., Millet, O., Davidson, N. O., Alonso, C. & Mato, J. M., Oct 2022, In: Hepatology. 76, 4, p. 1121-1134 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

2021

Inhibition of chylomicron assembly leads to dissociation of hepatic steatosis from inflammation and fibrosis

Xie, Y., Newberry, E. P., Brunt, E. M., Ballentine, S. J., Soleymanjahi, S., Molitor, E. A. & Davidson, N. O., Oct 2021, In: Journal of lipid research. 62, 100123.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Liver-Specific Deletion of Mouse Tm6sf2 Promotes Steatosis, Fibrosis, and Hepatocellular Cancer

Newberry, E., Hall, Z., Xie, Y., Molitor, E. A., Bayguinov, P. O., Strout, G. W., Fitzpatrick, J. A. J., Brunt, E. M., Griffin, J. L. & Davidson, N. O., Sep 2021, In: Hepatology. 74, 3, p. 1203-1219 17 p.

Research output: Contribution to journal › Article › peer-review

79 Scopus citations

Liver-specific deletion of Mttp versus Tm6sf2 reveals distinct defects in stepwise VLDL assembly

Newberry, E. P., Strout, G. W., Fitzpatrick, J. A. J. & Davidson, N. O., Apr 2021, In: Journal of lipid research. 62, 100080.

Research output: Contribution to journal › Comment/debate

Open Access

5 Scopus citations

2020

Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure

Zou, W., Rohatgi, N., Brestoff, J. R., Moley, J. R., Li, Y., Williams, J. W., Alippe, Y., Pan, H., Pietka, T. A., Mbalaviele, G., Newberry, E. P., Davidson, N. O., Dey, A., Shoghi, K. I., Head, R. D., Wickline, S. A., Randolph, G. J., Abumrad, N. A. & Teitelbaum, S. L., May 1 2020, In: Journal of Clinical Investigation. 130, 5, p. 2644-2656 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

2019

Hepatocyte and stellate cell deletion of liver fatty acid binding protein reveals distinct roles in fibrogenic injury

Newberry, E. P., Xie, Y., Lodeiro, C., Solis, R., Moritz, W., Kennedy, S., Barron, L., Onufer, E., Alpini, G., Zhou, T., Blaner, W. S., Chen, A. & Davidson, N. O., Mar 1 2019, In: FASEB Journal. 33, 3, p. 4610-4625 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Impaired Chylomicron Assembly Modifies Hepatic Metabolism Through Bile Acid–Dependent and Transmissible Microbial Adaptations

Xie, Y., Matsumoto, H., Kennedy, S., Newberry, E. P., Moritz, W., DeBosch, B. J., Moley, K. H., Rubin, D. C., Warner, B. W., Kau, A. L., Tarr, P. I., Wylie, T. N., Wylie, K. M. & Davidson, N. O., Oct 1 2019, In: Hepatology. 70, 4, p. 1168-1184 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

2018

Perilipin 5 and liver fatty acid binding protein function to restore quiescence in mouse hepatic stellate cells

Lin, J., Zheng, S., Attie, A. D., Keller, M. P., Bernlohr, D. A., Blaner, W. S., Newberry, E. P., Davidson, N. O. & Chen, A., 2018, In: Journal of lipid research. 59, 3, p. 416-428 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

2017

Cd36 knockout mice are protected against lithogenic diet-induced gallstones

Xie, Y., Cifarelli, V., Pietka, T., Newberry, E. P., Kennedy, S. M., Khalifeh-Soltani, A., Clugston, R., Atabai, K., Abumrad, N. A. & Davidson, N. O., 2017, In: Journal of lipid research. 58, 8, p. 1692-1701 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Prevention of hepatic fibrosis with liver microsomal triglyceride transfer protein deletion in liver fatty acid binding protein null mice

Newberry, E. P., Xie, Y., Kennedy, S. M., Graham, M. J., Crooke, R. M., Jiang, H., Chen, A., Ory, D. S. & Davidson, N. O., Mar 1 2017, In: Hepatology. 65, 3, p. 836-852 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

2016

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

DeBosch, B. J., Heitmeier, M. R., Mayer, A. L., Higgins, C. B., Crowley, J. R., Kraft, T. E., Chi, M., Newberry, E. P., Chen, Z., Finck, B. N., Davidson, N. O., Yarasheski, K. E., Hruz, P. W. & Moley, K. H., Feb 23 2016, In: Science signaling. 9, 416, RA21.

Research output: Contribution to journal › Article › peer-review

Open Access

235 Scopus citations

2015

Phenotypic divergence in two lines of L-Fabp^-/- mice reflects substrain differences and environmental modifiers

Newberry, E. P., Kennedy, S., Xie, Y., Luo, J., Jiang, H., Ory, D. S. & Davidson, N. O., 2015, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 8, p. G648-G661

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

2014

Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice

Xie, Y., Fung, H. Y. J., Newberry, E. P., Kennedy, S., Luo, J., Crooke, R. M., Graham, M. J. & Davidson, N. O., Mar 2014, In: Journal of lipid research. 55, 3, p. 540-548 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2013

Liver fatty acid-binding protein (L-Fabp) modifies intestinal fatty acid composition and adenoma formation in Apc^Min/+ mice

Dharmarajan, S., Newberry, E. P., Montenegro, G., Nalbantoglu, I., Davis, V. R., Clanahan, M. J., Blanc, V., Xie, Y., Luo, J., Fleshman, J. W., Kennedy, S. & Davidson, N. O., Oct 2013, In: Cancer Prevention Research. 6, 10, p. 1026-1037 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver disease

Chen, A., Tang, Y., Davis, V., Hsu, F. F., Kennedy, S. M., Song, H., Turk, J., Brunt, E. M., Newberry, E. P. & Davidson, N. O., Jun 2013, In: Hepatology. 57, 6, p. 2202-2212 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

80 Scopus citations

2012

Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp ^-/- mice

Newberry, E. P., Kennedy, S. M., Xie, Y., Luo, J., Crooke, R. M., Graham, M. J., Fu, J., Piomelli, D. & Davidson, N. O., Apr 2012, In: Journal of lipid research. 53, 4, p. 744-754 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

2009

Decreased expression of cholesterol 7α-hydroxylase and altered bile acid metabolism in Apobec-1^-l- mice lead to increased gallstone susceptibility

Xie, Y., Blanc, V., Kerr, T. A., Kennedy, S., Luo, J., Newberry, E. P. & Davidson, N. O., Jun 19 2009, In: Journal of Biological Chemistry. 284, 25, p. 16860-16871 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Diet-induced alterations in intestinal and extrahepatic lipid metabolism in liver fatty acid binding protein knockout mice

Newberry, E. P., Kennedy, S. M., Xie, Y., Luo, J. & Davidson, N. O., 2009, In: Molecular and Cellular Biochemistry. 326, 1-2, p. 79-86 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Fatty acid transport protein 4 is dispensable for intestinal lipid absorption in mice

Shim, J., Moulson, C. L., Newberry, E. P., Lin, M. H., Xie, Y., Kennedy, S. M., Miner, J. H. & Davidson, N. O., Apr 2009, In: Journal of lipid research. 50, 3, p. 491-500 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

72 Scopus citations

Increased susceptibility to diet-induced gallstones in liver fatty acid binding protein knockout mice

Xie, Y., Newberry, E. P., Kennedy, S. M., Luo, J. & Davidson, N. O., May 2009, In: Journal of lipid research. 50, 5, p. 977-987 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Intestinal Lipid Absorption, GLP-2, and CD36: Still More Mysteries to Moving Fat

Newberry, E. P. & Davidson, N. O., Sep 2009, In: Gastroenterology. 137, 3, p. 775-778 4 p.

Research output: Contribution to journal › Editorial

Open Access

16 Scopus citations

Liver fatty acid binding protein (L-FABP) as a target for the prevention of high fat diet induced obesity and hepatic steatosis

Newberry, E. P. & Davidson, N. O., 2009, In: Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 9, 1, p. 30-37 8 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2008

Altered hepatic triglyceride content after partial hepatectomy without impaired liver regeneration in multiple murine genetic models

Newberry, E. P., Kennedy, S. M., Xie, Y., Luo, J., Stanley, S. E., Semenkovich, C. F., Crooke, R. M., Graham, M. J. & Davidson, N. O., Oct 2008, In: Hepatology. 48, 4, p. 1097-1105 9 p.

Research output: Contribution to journal › Article › peer-review

97 Scopus citations

ApoB100 is required for increased VLDL-triglyceride secretion by microsomal triglyceride transfer protein in ob/ob mice

Chen, Z., Newberry, E. P., Norris, J. Y., Xie, Y., Luo, J., Kennedy, S. M. & Davidson, N. O., Sep 2008, In: Journal of lipid research. 49, 9, p. 2013-2022 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2007

Deletion of the AU-rich RNA binding protein apobec-1 reduces intestinal tumor burden in Apc^min mice

Blanc, V., Henderson, J. O., Newberry, R. D., Xie, Y., Cho, S. J., Newberry, E. P., Kennedy, S., Rubin, D. C., Wang, H. L., Luo, J. & Davidson, N. O., Sep 15 2007, In: Cancer research. 67, 18, p. 8565-8573 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Diet-induced obesity and hepatic steatosis in L-Fabp^-/- mice is abrogated with SF, but not PUFA, feeding and attenuated after cholesterol supplementation

Newberry, E. P., Kennedy, S. M., Xie, Y., Sternard, B. T., Luo, J. & Davidson, N. O., 2007, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 294, 1, p. G307-G314

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Keratinocyte-specific expression of fatty acid transport protein 4 rescues the wrinkle-free phenotype in Slc27a4/Fatp4 mutant mice

Moulson, C. L., Lin, M. H., White, J. M., Newberry, E. P., Davidson, N. O. & Miner, J. H., May 25 2007, In: Journal of Biological Chemistry. 282, 21, p. 15912-15920 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

2006

Compensatory increase in hepatic lipogenesis in mice with conditional intestine-specific Mttp deficiency

Xie, Y., Newberry, E. P., Young, S. G., Robine, S., Hamilton, R. L., Wong, J. S., Luo, J., Kennedy, S. & Davidson, N. O., Feb 17 2006, In: Journal of Biological Chemistry. 281, 7, p. 4075-4086 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

111 Scopus citations

Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis

Spann, N. J., Kang, S., Li, A. C., Chen, A. Z., Newberry, E. P., Davidson, N. O., Hui, S. T. Y. & Davis, R. A., Nov 3 2006, In: Journal of Biological Chemistry. 281, 44, p. 33066-33077 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

62 Scopus citations

Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice

Newberry, E. P., Xie, Y., Kennedy, S. M., Luo, J. & Davidson, N. O., Nov 2006, In: Hepatology. 44, 5, p. 1191-1205 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

183 Scopus citations

2005

Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality

Blanc, V., Henderson, J. O., Newberry, E. P., Kennedy, S., Luo, J. & Davidson, N. O., Aug 2005, In: Molecular and cellular biology. 25, 16, p. 7260-7269 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

2003

Biliary lipid secretion, membrane pumps, and the metabolic response to fasting: Distinct PPAR-ts of a common regulatory pathway

Newberry, E. P. & Davidson, N. O., Jan 1 2003, In: Gastroenterology. 124, 1, p. 254-257 4 p.

Research output: Contribution to journal › Editorial

Decreased Hepatic Triglyceride Accumulation and Altered Fatty Acid Uptake in Mice with Deletion of the Liver Fatty Acid-binding Protein Gene

Newberry, E. P., Xie, Y., Kennedy, S., Han, X., Buhman, K. K., Luo, J., Gross, R. W. & Davidson, N. O., Dec 19 2003, In: Journal of Biological Chemistry. 278, 51, p. 51664-51672 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

255 Scopus citations

2000

Ets domain transcription factor PE1 suppresses human interstitial collagenase promoter activity by antagonizing protein-DNA interactions at a critical AP1 element

Bidder, M., Loewy, A. P., Latifi, T., Newberry, E. P., Ferguson, G., Willis, D. M. & Towler, D. A., Aug 1 2000, In: Biochemistry. 39, 30, p. 8917-8928 12 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

1999

The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter

Newberry, E. P., Latifi, T. & Towler, D. A., Aug 17 1999, In: Biochemistry. 38, 33, p. 10678-10690 13 p.

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

1998

Reciprocal regulation of osteocalcin transcription by the homeodomain proteins Msx2 and Dlx5

Newberry, E. P., Latifi, T. & Towler, D. A., Nov 17 1998, In: Biochemistry. 37, 46, p. 16360-16368 9 p.

Research output: Contribution to journal › Article › peer-review

123 Scopus citations

Reciprocal regulation of the osteocalcin promoter by the homeodomain proteins DLX5 & MSX2

Towler, D. A., Newberry, E. P. & Latifi, T., Dec 1 1998, In: FASEB Journal. 12, 8, p. A1322

Research output: Contribution to journal › Article › peer-review

1997

Fibroblast growth factor receptor signaling activates the human interstitial collagenase promoter via the bipartite Ets-AP1 element

Newberry, E. P., Willis, D., Latifi, T., Boudreaux, J. M. & Towler, D. A., 1997, In: Molecular Endocrinology. 11, 8, p. 1129-1144 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

91 Scopus citations

Stimulus-selective inhibition of rat osteocalcin promoter induction and protein-DNA interactions by the homeodomain repressor Msx2

Newberry, E. P., Boudreaux, J. M. & Towler, D. A., Nov 21 1997, In: Journal of Biological Chemistry. 272, 47, p. 29607-29613 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Structure-function analysis of Msx2-mediated transcriptional suppression

Newberry, E. P., Latifi, T., Battaile, J. T. & Towler, D. A., Aug 26 1997, In: Biochemistry. 36, 34, p. 10451-10462 12 p.

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

1996

The rat osteocalcin fibroblast growth factor (FGF)-responsive element: An okadaic acid-sensitive, FGF-selective transcriptional response motif

Newberry, E. P., Boudreaux, J. M. & Towler, D. A., 1996, In: Molecular Endocrinology. 10, 8, p. 1029-1040 12 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

1995

Cell-cycle-dependent modulation of EGF-receptor-mediated signaling

Newberry, E. P. & Pike, L. J., 1995, In: Biochemical and Biophysical Research Communications. 208, 1, p. 253-259 7 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

1994

Mutation of proline-1003 to glycine in the epidermal growth factor (EGF) receptor enhances responsiveness to EGF

Schuh, S. M., Newberry, E. P., Dalton, M. A. & Pike, L. J., Jul 1994, In: Molecular biology of the cell. 5, 7, p. 739-746 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Elizabeth Newberry

Research output

Search results