Douglas Mann

2023

The Immunology of Takotsubo Syndrome

Lim, K. R. Q., Mann, D. L., Kenzaka, T. & Hayashi, T., 2023, In: Frontiers in immunology. 14, 1254011.

Research output: Contribution to journal › Review article › peer-review

Open Access

2022

Advances in Our Clinical Understanding of Autonomic Regulation Therapy Using Vagal Nerve Stimulation in Patients Living With Heart Failure

Konstam, M. A., Mann, D. L., Udelson, J. J. E., Ardell, J. L., De Ferrari, G. M., Cowie, M. R., Klein, H. U., Gregory, D. D., Massaro, J. M., Libbus, I., DiCarlo, L. A., Butler, J., Parker, J. D. & Teerlink, J. R., Apr 21 2022, In: Frontiers in Physiology. 13, 857538.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

2020

COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities

Ky, B. & Mann, D. L., Jun 2020, In: JACC: CardioOncology. 2, 2, p. 254-269 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities

Ky, B. & Mann, D. L., May 2020, In: JACC: Basic to Translational Science. 5, 5, p. 501-517 17 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

17 Scopus citations

Heart Failure With Recovered Left Ventricular Ejection Fraction: JACC Scientific Expert Panel

Wilcox, J. E., Fang, J. C., Margulies, K. B. & Mann, D. L., Aug 11 2020, In: Journal of the American College of Cardiology. 76, 6, p. 719-734 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

180 Scopus citations

Reappraising the role of inflammation in heart failure

Adamo, L., Rocha-Resende, C., Prabhu, S. D. & Mann, D. L., May 1 2020, In: Nature Reviews Cardiology. 17, 5, p. 269-285 17 p.

Research output: Contribution to journal › Review article › peer-review

434 Scopus citations

Sacubitril/Valsartan in Advanced Heart Failure With Reduced Ejection Fraction: Rationale and Design of the LIFE Trial

LIFE Investigators, Oct 2020, In: JACC: Heart Failure. 8, 10, p. 789-799 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

46 Scopus citations

The Emerging Role of B Lymphocytes in Cardiovascular Disease

Adamo, L., Rocha-Resende, C. & Mann, D. L., Apr 26 2020, In: Annual Review of Immunology. 38, p. 99-121 23 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

37 Scopus citations

2019

The continuous heart failure spectrum: Moving beyond an ejection fraction classification

Triposkiadis, F., Butler, J., Abboud, F. M., Armstrong, P. W., Adamopoulos, S., Atherton, J. J., Backs, J., Bauersachs, J., Burkhoff, D., Bonow, R. O., Chopra, V. K., De Boer, R. A., De Windt, L., Hamdani, N., Hasenfuss, G., Heymans, S., Hulot, J. S., Konstam, M., Lee, R. T. & Linke, W. A. & 22 others, Lunde, I. G., Lyon, A. R., Maack, C., Mann, D. L., Mebazaa, A., Mentz, R. J., Nihoyannopoulos, P., Papp, Z., Parissis, J., Pedrazzini, T., Rosano, G., Rouleau, J., Seferovic, P. M., Shah, A. M., Starling, R. C., Tocchetti, C. G., Trochu, J. N., Thum, T., Zannad, F., Brutsaert, D. L., Segers, V. F. & De Keulenaer, G. W., Jul 7 2019, In: European heart journal. 40, 26, p. 2155-2163B

Research output: Contribution to journal › Review article › peer-review

Open Access

198 Scopus citations

2018

Cardiac contractility modulation in 2018

Borggrefe, M. & Mann, D. L., 2018, In: Circulation. 138, 24, p. 2738-2740 3 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

37 Scopus citations

2017

Diagnosis and management of adult hereditary cardio-neuromuscular disorders: A model for the multidisciplinary care of complex genetic disorders

Sommerville, R. B., Vincenti, M. G., Winborn, K., Casey, A., Stitziel, N. O., Connolly, A. M. & Mann, D. L., Jan 1 2017, In: Trends in Cardiovascular Medicine. 27, 1, p. 51-58 8 p.

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

High-resolution chromatin mapping in heart failure: Some answers, but more questions

Mann, D. L., 2017, In: Circulation. 136, 17, p. 1626-1628 3 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Left ventricular assist device-induced reverse remodeling: it’s not just about myocardial recovery

Marinescu, K. K., Uriel, N., Mann, D. L. & Burkhoff, D., Jan 2 2017, In: Expert Review of Medical Devices. 14, 1, p. 15-26 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

29 Scopus citations

Status of Early-Career Academic Cardiology: A Global Perspective

Tong, C. W., Madhur, M. S., Rzeszut, A. K., Abdalla, M., Abudayyeh, I., Alexanderson, E., Buber, J., Feldman, D. N., Gopinathannair, R., Hira, R. S., Kates, A. M., Kessler, T., Leung, S., Raj, S. R., Spatz, E. S., Turner, M. B., Valente, A. M., West, K., Sivaram, C. A. & Hill, J. A. & 2 others, Mann, D. L. & Freeman, A. M., Oct 31 2017, In: Journal of the American College of Cardiology. 70, 18, p. 2290-2303 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

25 Scopus citations

Structural and Functional Phenotyping of the Failing Heart: Is the Left Ventricular Ejection Fraction Obsolete?

Bristow, M. R., Kao, D. P., Breathett, K. K., Altman, N. L., Gorcsan, J., Gill, E. A., Lowes, B. D., Gilbert, E. M., Quaife, R. A. & Mann, D. L., Nov 2017, In: JACC: Heart Failure. 5, 11, p. 772-781 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

56 Scopus citations

Targeting Myocardial Energetics in the Failing Heart: Are We There Yet?

Mann, D. L., Dec 1 2017, In: Circulation: Heart Failure. 10, 12, e004658.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

2016

Emerging Research Directions in Adult Congenital Heart Disease A Report from an NHLBI/ACHA Working Group

Gurvitz, M., Burns, K. M., Brindis, R., Broberg, C. S., Daniels, C. J., Fuller, S. M. P. N., Honein, M. A., Khairy, P., Kuehl, K. S., Landzberg, M. J., Mahle, W. T., Mann, D. L., Marelli, A., Newburger, J. W., Pearson, G. D., Starling, R. C., Tringali, G. R., Valente, A. M., Wu, J. C. & Califf, R. M., Apr 26 2016, In: Journal of the American College of Cardiology. 67, 16, p. 1956-1964 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

78 Scopus citations

Neurohormonal activation in heart failure with reduced ejection fraction

Hartupee, J. & Mann, D. L., Dec 12 2016, In: Nature Reviews Cardiology. 14, 1, p. 30-38 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

384 Scopus citations

Neuromodulation of the Failing Heart: Lost in Translation?

Byku, M. & Mann, D. L., Apr 1 2016, In: JACC: Basic to Translational Science. 1, 3, p. 95-106 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

45 Scopus citations

Role of inflammatory cells in fibroblast activation

Hartupee, J. & Mann, D. L., Apr 1 2016, In: Journal of Molecular and Cellular Cardiology. 93, p. 143-148 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

69 Scopus citations

2015

Imaging systemic inflammatory networks in ischemic heart disease

Nahrendorf, M., Frantz, S., Swirski, F. K., Mulder, W. J. M., Randolph, G., Ertl, G., Ntziachristos, V., Piek, J. J., Stroes, E. S., Schwaiger, M., Mann, D. L. & Fayad, Z. A., Apr 21 2015, In: Journal of the American College of Cardiology. 65, 15, p. 1583-1591 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

69 Scopus citations

Innate immunity and the failing heart: The cytokine hypothesis revisited

Mann, D. L., Mar 27 2015, In: Circulation research. 116, 7, p. 1254-1268 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

532 Scopus citations

National institutes of health career development awards for cardiovascular physician-scientists recent trends and strategies for success

Lindman, B. R., Tong, C. W., Carlson, D. E., Balke, C. W., Jackson, E. A., Madhur, M. S., Barac, A., Abdalla, M., Brittain, E. L., Desai, N., Kates, A. M., Freeman, A. M. & Mann, D. L., Oct 20 2015, In: Journal of the American College of Cardiology. 66, 16, p. 1816-1827 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

16 Scopus citations

Role of innate and adaptive immune mechanisms in cardiac injury and repair

Epelman, S., Liu, P. P. & Mann, D. L., Jan 23 2015, In: Nature Reviews Immunology. 15, 2, p. 117-129 13 p.

Research output: Contribution to journal › Review article › peer-review

470 Scopus citations

2014

Diabetic Cardiomyopathy: Distinct and Preventable Entity or Inevitable Consequence?

Schilling, J. D. & Mann, D. L., Sep 30 2014, In: Current Cardiovascular Risk Reports. 8, 12, p. 1-9 9 p., 417.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

The evolution of modern theory and therapy for heart failure

Mann, D. L., Dec 1 2014, In: Progress in Pediatric Cardiology. 37, 1-2, p. 9-12 4 p.

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

2013

The treatment of heart failure in the 21st century: is the glass half empty or half full?

Bozkurt, B. & Mann, D. L., 2013, In: Methodist DeBakey cardiovascular journal. 9, 1, p. 3-5 3 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

4 Scopus citations

2012

Diabetic Cardiomyopathy: Bench to Bedside

Schilling, J. D. & Mann, D. L., Oct 2012, In: Heart Failure Clinics. 8, 4, p. 619-631 13 p.

Research output: Contribution to journal › Review article › peer-review

98 Scopus citations

Is myocardial recovery possible and how do you measure it?

Mann, D. L. & Burkhoff, D., Jun 2012, In: Current Cardiology Reports. 14, 3, p. 293-298 6 p.

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Myocardial recovery and the failing heart: Myth, magic, or molecular target?

Mann, D. L., Barger, P. M. & Burkhoff, D., Dec 18 2012, In: Journal of the American College of Cardiology. 60, 24, p. 2465-2472 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

213 Scopus citations

2011

In search of new therapeutic targets and strategies for heart failure: Recent advances in basic science

Shah, A. M. & Mann, D. L., 2011, In: The Lancet. 378, 9792, p. 704-712 9 p.

Research output: Contribution to journal › Review article › peer-review

256 Scopus citations

Role of microRNAs in cardiac remodeling and heart failure

Topkara, V. K. & Mann, D. L., Apr 2011, In: Cardiovascular Drugs and Therapy. 25, 2, p. 171-182 12 p.

Research output: Contribution to journal › Review article › peer-review

122 Scopus citations

Therapeutic targeting of innate immunity in the failing heart

Topkara, V. K., Evans, S., Zhang, W., Epelman, S., Staloch, L., Barger, P. M. & Mann, D. L., Oct 2011, In: Journal of Molecular and Cellular Cardiology. 51, 4, p. 594-599 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

38 Scopus citations

2010

Biomarkers of inflammation in heart failure

Bozkurt, B., Mann, D. L. & Deswal, A., Jul 2010, In: Heart Failure Reviews. 15, 4, p. 331-341 11 p.

Research output: Contribution to journal › Review article › peer-review

164 Scopus citations

Cardiac remodelling and myocardial recovery: Lost in translation?

Mann, D. L., Bogaev, R. & Buckberg, G. D., Aug 2010, In: European Journal of Heart Failure. 12, 8, p. 789-796 8 p.

Research output: Contribution to journal › Review article › peer-review

50 Scopus citations

Clinical applications of miRNAs in cardiac remodeling and heart failure

Topkara, V. K. & Mann, D. L., Sep 2010, In: Personalized Medicine. 7, 5, p. 531-548 18 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

26 Scopus citations

Heart failure guidelines, performance measures, and the practice of medicine: Mind the gap

Ghali, J. K., Massie, B. M., Mann, D. L. & Rich, M. W., Dec 14 2010, In: Journal of the American College of Cardiology. 56, 25, p. 2077-2080 4 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

20 Scopus citations

Highlights of the 2009 Scientific Sessions of the Heart Failure Society of America, Boston, MA, September 13-16, 2009

O'Connor, C. M., Koch, W. J. & Mann, D. L., Jan 2010, In: Journal of cardiac failure. 16, 1, p. 2-8 7 p.

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Innate immunity in the adult mammalian heart: for whom the cell tolls.

Mann, D. L., Topkara, V. K., Evans, S. & Barger, P. M., 2010, In: Transactions of the American Clinical and Climatological Association. 121, p. 34-50; discussion 50-51

Research output: Contribution to journal › Review article › peer-review

55 Scopus citations

2009

Acute decompensated heart failure: Contemporary medical management

Joseph, S. M., Cedars, A. M., Ewald, G. A., Geltman, E. M. & Mann, D. L., 2009, In: Texas Heart Institute journal. 36, 6, p. 510-520 11 p.

Research output: Contribution to journal › Review article › peer-review

113 Scopus citations

Advanced Heart Failure and Transplant Cardiology: A Subspecialty Is Born

Konstam, M. A., Jessup, M., Francis, G. S., Mann, D. L. & Greenberg, B., Mar 10 2009, In: Journal of the American College of Cardiology. 53, 10, p. 834-836 3 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

26 Scopus citations

Modulation of left ventricular dilation remodeling with epicardial restraint devices in postmyocardial infarction heart failure

Mann, D. L., Topkara, V. K. & Kondareddy, S., Dec 2009, In: Current Heart Failure Reports. 6, 4, p. 229-235 7 p.

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

2008

Experimental and Clinical Basis for the Use of Statins in Patients With Ischemic and Nonischemic Cardiomyopathy

Ramasubbu, K., Estep, J., White, D. L., Deswal, A. & Mann, D. L., Jan 29 2008, In: Journal of the American College of Cardiology. 51, 4, p. 415-426 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access