Research output per year
Research output per year
- 1 - 50 out of 64 results
Search results
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2025
Splenic CD169+Tim4+Marginal Metallophilic Macrophages Are Essential for Wound Healing After Myocardial Infarction
Ismahil, M. A., Zhou, G., Rajasekar, S., Gao, M., Bansal, S. S., Patel, B., Limdi, N., Xie, M., Antipenko, S., Rokosh, G., Hamid, T. & Prabhu, S., 2025, (Accepted/In press) In: Circulation.Research output: Contribution to journal › Article › peer-review
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2024
Neutrophils are indispensable for adverse cardiac remodeling in heart failure
Antipenko, S., Mayfield, N., Jinno, M., Gunzer, M., Ismahil, M. A., Hamid, T., Prabhu, S. D. & Rokosh, G., Apr 2024, In: Journal of Molecular and Cellular Cardiology. 189, p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2023
Genetic deletion of 12/15 lipoxygenase delays vascular remodeling and limits cardiorenal dysfunction after pressure overload
Lee, D. H., Kain, V., Wang, D. Z., Rokosh, D. G., Prabhu, S. D. & Halade, G. V., Sep 2023, In: Journal of Molecular and Cellular Cardiology Plus. 5, 100046.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling
Hamid, T., Xu, Y., Ismahil, M. A., Rokosh, G., Jinno, M., Zhou, G., Wang, Q. & Prabhu, S. D., May 2022, In: JACC: Basic to Translational Science. 7, 5, p. 465-483 19 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Differential requirement for DICER1 activity during the development of mitral and tricuspid valves
Yan, S., Peng, Y., Lu, J., Shakil, S., Shi, Y., Crossman, D. K., Johnson, W. H., Liu, S., Rokosh, D. G., Lincoln, J., Wang, Q. & Jiao, K., Sep 2022, In: Journal of cell science. 135, 17, jcs259783.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2019
Correction: The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-related kinase (ERK)/NRF2 signaling pathway and cytokine release (Journal of Biological Chemistry (2012) 287:40 (33720-33732) DOI:10.1074/jbc.M112.385542)
Cai, C., Teng, L., Vu, D., He, J. Q., Guo, Y., Li, Q., Tang, X. L., Rokosh, G., Bhatnagar, A. & Bolli, R., Mar 22 2019, In: Journal of Biological Chemistry. 294, 12, p. 4725-4727 3 p.Research output: Contribution to journal › Comment/debate
Open Access1 Scopus citations -
Dysfunctional and Proinflammatory Regulatory T-Lymphocytes Are Essential for Adverse Cardiac Remodeling in Ischemic Cardiomyopathy
Bansal, S. S., Ismahil, M. A., Goel, M., Zhou, G., Rokosh, G., Hamid, T. & Prabhu, S. D., Jan 8 2019, In: Circulation. 139, 2, p. 206-221 16 p.Research output: Contribution to journal › Article › peer-review
Open Access232 Scopus citations -
Inducible cardiac-specific overexpression of cyclooxygenase-2 (COX-2) confers resistance to ischemia/reperfusion injury
Guo, Y., Nong, Y., Tukaye, D. N., Rokosh, G., Du, J., Zhu, X., Book, M., Tomlin, A., Li, Q. & Bolli, R., Sep 1 2019, In: Basic Research in Cardiology. 114, 5, 32.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Optimized protocols for isolation, fixation, and flow cytometric characterization of leukocytes in ischemic hearts
Covarrubias, R., Ismahil, M. A., Rokosh, G., Hamid, T., Accornero, F., Singh, H., Gumina, R. J., Prabhu, S. D. & Bansal, S. S., Sep 2019, In: American Journal of Physiology - Heart and Circulatory Physiology. 317, 3, p. H658-H666Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Response by Bansal et al to Letter Regarding Article, "dysfunctional and Proinflammatory Regulatory T-Lymphocytes Are Essential for Adverse Cardiac Remodeling in Ischemic Cardiomyopathy"
Bansal, S. S., Ismahil, M. A., Goel, M., Zhou, G., Rokosh, G., Hamid, T. & Prabhu, S. D., Jun 11 2019, In: Circulation. 139, 24, p. E1035-E1036Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice
Sun, Q., Peng, Y., Zhao, Q., Yan, S., Liu, S., Yang, Q., Liu, K., Rokosh, D. G. & Jiao, K., Aug 1 2019, In: Developmental Biology. 452, 1, p. 1-7 7 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2018
CCR2+ Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac Remodeling During Pressure Overload
Patel, B., Bansal, S. S., Ismahil, M. A., Hamid, T., Rokosh, G., Mack, M. & Prabhu, S. D., Apr 2018, In: JACC: Basic to Translational Science. 3, 2, p. 230-244 15 p.Research output: Contribution to journal › Article › peer-review
Open Access216 Scopus citations -
2017
Activated T lymphocytes are essential drivers of pathological remodeling in ischemic heart failure
Bansal, S. S., Ismahil, M. A., Goel, M., Patel, B., Hamid, T., Rokosh, G. & Prabhu, S. D., Mar 1 2017, In: Circulation: Heart Failure. 10, 3, e003688.Research output: Contribution to journal › Article › peer-review
Open Access248 Scopus citations -
Elevating CXCR7 Improves Angiogenic Function of EPCs via Akt/GSK-3β/Fyn-Mediated Nrf2 Activation in Diabetic Limb Ischemia
Dai, X., Yan, X., Zeng, J., Chen, J., Wang, Y., Chen, J., Li, Y., Barati, M. T., Wintergerst, K. A., Pan, K., Nystoriak, M. A., Conklin, D. J., Rokosh, G., Epstein, P. N., Li, X. & Tan, Y., Mar 3 2017, In: Circulation research. 120, 5, p. e7-e23Research output: Contribution to journal › Article › peer-review
Open Access123 Scopus citations -
Leukocyte iNOS is required for inflammation and pathological remodeling in ischemic heart failure
Kingery, J. R., Hamid, T., Lewis, R. K., Ismahil, M. A., Bansal, S. S., Rokosh, G., Townes, T. M., Ildstad, S. T., Jones, S. P. & Prabhu, S. D., Mar 1 2017, In: Basic Research in Cardiology. 112, 2, 19.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
2016
Long-Term Outcome of Administration of c-kitPOS Cardiac Progenitor Cells after Acute Myocardial Infarction: Transplanted Cells Do not Become Cardiomyocytes, but Structural and Functional Improvement and Proliferation of Endogenous Cells Persist for at Least One Year
Tang, X. L., Li, Q., Rokosh, G., Sanganalmath, S. K., Chen, N., Ou, Q., Stowers, H., Hunt, G. & Bolli, R., Apr 1 2016, In: Circulation research. 118, 7, p. 1091-1105 15 p.Research output: Contribution to journal › Article › peer-review
Open Access144 Scopus citations -
Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice
Peng, Y., Song, L., Li, D., Kesterson, R., Wang, J., Wang, L., Rokosh, G., Wu, B., Wang, Q. & Jiao, K., Nov 1 2016, In: Cardiovascular Research. 112, 2, p. 532-542 11 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2015
Effects of intracoronary infusion of escalating doses of cardiac stem cells in rats with acute myocardial infarction
Tang, X. L., Rokosh, G., Sanganalmath, S. K., Tokita, Y., Keith, M. C. L., Shirk, G., Stowers, H., Hunt, G. N., Wu, W., Dawn, B. & Bolli, R., May 1 2015, In: Circulation: Heart Failure. 8, 4, p. 757-765 9 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow
Adamiak, M., Borkowska, S., Wysoczynski, M., Suszynska, M., Kucia, M., Rokosh, G., Abdel-Latif, A., Ratajczak, J. & Ratajczak, M. Z., 2015, In: Oncotarget. 6, 22, p. 18819-18828 10 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Feasibility Study of Particulate Extracellular Matrix (P-ECM) and Left Ventricular Assist Device (HVAD) Therapy in Chronic Ischemic Heart Failure Bovine Model
Soucy, K. G., Smith, E. F., Monreal, G., Rokosh, G., Keller, B. B., Yuan, F., Matheny, R. G., Fallon, A. M., Lewis, B. C., Sherwood, L. C., Sobieski, M. A., Giridharan, G. A., Koenig, S. C. & Slaughter, M. S., Jul 21 2015, In: ASAIO Journal. 61, 2, p. 161-169 9 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury
Conklin, D. J., Guo, Y., Jagatheesan, G., Kilfoil, P. J., Haberzettl, P., Hill, B. G., Baba, S. P., Guo, L., Wetzelberger, K., Obal, D., Gregg Rokosh, D., Prough, R. A., Prabhu, S. D., Velayutham, M., Zweier, J. L., David Hoetker, J., Riggs, D. W., Srivastava, S., Bolli, R. & Bhatnagar, A., Aug 14 2015, In: Circulation research. 117, 5, p. 437-449 13 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Identification of Heme Oxygenase 1 (HO-1) as a Novel Negative Regulator of Mobilization of Hematopoietic Stem/Progenitor Cells
Wysoczynski, M., Ratajczak, J., Pedziwiatr, D., Rokosh, G., Bolli, R. & Ratajczak, M. Z., Feb 2015, In: Stem Cell Reviews and Reports. 11, 1, p. 110-118 9 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Inhibition of mammalian target of rapamycin protects against reperfusion injury in diabetic heart through STAT3 signaling
Das, A., Salloum, F. N., Filippone, S. M., Durrant, D. E., Rokosh, G., Bolli, R. & Kukreja, R. C., May 1 2015, In: Basic Research in Cardiology. 110, 3Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
2014
Cigarette smoke adversely affects functions and cell membrane integrity in c-kit+ cardiac stem cells
Sumanasekera, W. K., Tran, D. M., Sumanasekera, T. U., Le, N., Dao, H. T. & Rokosh, G. D., Apr 2014, In: Cell Biology and Toxicology. 30, 2, p. 113-125 13 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Co-activation of nuclear factor-κB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts
Madonna, R., Geng, Y. J., Bolli, R., Rokosh, G., Ferdinandy, P., Patterson, C. & De Caterina, R., Jul 11 2014, In: Journal of Biological Chemistry. 289, 28, p. 19585-19598 14 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Complement component 3 is necessary to preserve myocardium and myocardial function in chronic myocardial infarction
Wysoczynski, M., Solanki, M., Borkowska, S., Van Hoose, P., Brittian, K. R., Prabhu, S. D., Ratajczak, M. Z. & Rokosh, G., Sep 2014, In: STEM CELLS. 32, 9, p. 2502-2515 14 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Stromal cell derived factor-1α promotes C-Kit+ cardiac stem/progenitor cell quiescence through casein kinase 1α and GSK3β
Dimova, N., Wysoczynski, M. & Rokosh, G., Feb 2014, In: STEM CELLS. 32, 2, p. 487-499 13 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
2013
Long-term engraftment and angiogenic properties of lentivirally transduced adipose tissue-derived stromal cells
Madonna, R., Bolli, R., Rokosh, G. & De Caterina, R., May 2013, In: Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology. 54, 1, p. 13-24 12 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Mechanisms of stem cell effects: Insights from MRI
Rokosh, G., Ghafghazi, S. & Bolli, R., Dec 2013, In: Minerva Cardioangiologica. 61, 6, p. 605-616 12 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Targeting phosphatidylinositol 3-kinase-Akt through hepatocyte growth factor for cardioprotection
Madonna, R., Bolli, R., Rokosh, G. & De Caterina, R., Apr 2013, In: Journal of Cardiovascular Medicine. 14, 4, p. 249-253 5 p.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations -
2012
Cardiomyocyte-restricted overexpression of extracellular superoxide dismutase increases nitric oxide bioavailability and reduces infarct size after ischemia/reperfusion
Obal, D., Dai, S., Keith, R., Dimova, N., Kingery, J., Zheng, Y. T., Zweier, J., Velayutham, M., Prabhu, S. D., Li, Q., Conklin, D., Yang, D., Bhatnagar, A., Bolli, R. & Rokosh, G., Nov 2012, In: Basic Research in Cardiology. 107, 6, 305.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Insights into gene therapy for critical limb ischemia: The devil is in the details
Madonna, R. & Rokosh, G., Aug 19 2012, In: Vascular Pharmacology. 57, 1, p. 10-14 5 p.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations -
The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning
Guo, Y., Tukaye, D. N., Wu, W. J., Zhu, X., Book, M., Tan, W., Jones, S. P., Rokosh, G., Narumiya, S., Li, Q. & Bolli, R., Jul 23 2012, In: PloS one. 7, 7, e41178.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-regulated kinase (ERK)/NRF2 signaling pathway and cytokine release
Cai, C., Teng, L., Vu, D., He, J. Q., Guo, Y., Li, Q., Tang, X. L., Rokosh, G., Bhatnagar, A. & Bolli, R., Sep 28 2012, In: Journal of Biological Chemistry. 287, 40, p. 33720-33732 13 p.Research output: Contribution to journal › Article › peer-review
Open Access87 Scopus citations -
2011
A murine model of inducible, cardiac-specific deletion of STAT3: Its use to determine the role of STAT3 in the upregulation of cardioprotective proteins by ischemic preconditioning
Bolli, R., Stein, A. B., Guo, Y., Wang, O. L., Rokosh, G., Dawn, B., Molkentin, J. D., Sanganalmath, S. K., Zhu, Y. & Xuan, Y. T., Apr 2011, In: Journal of Molecular and Cellular Cardiology. 50, 4, p. 589-597 9 p.Research output: Contribution to journal › Article › peer-review
87 Scopus citations -
Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): Initial results of a randomised phase 1 trial
Bolli, R., Chugh, A. R., D'Amario, D., Loughran, J. H., Stoddard, M. F., Ikram, S., Beache, G. M., Wagner, S. G., Leri, A., Hosoda, T., Sanada, F., Elmore, J. B., Goichberg, P., Cappetta, D., Solankhi, N. K., Fahsah, I., Rokosh, D. G., Slaughter, M. S., Kajstura, J. & Anversa, P., 2011, In: The Lancet. 378, 9806, p. 1847-1857 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1155 Scopus citations -
2010
Cardiac progenitor cells and bone marrow-derived very small embryonic-like stem cells for cardiac repair after myocardial infarction
Tang, X. L., Rokosh, D. G., Guo, Y. & Bolli, R., Mar 2010, In: Circulation Journal. 74, 3, p. 390-404 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access54 Scopus citations -
Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart
Wang, G., Hamid, T., Keith, R. J., Zhou, G., Partridge, C. R., Xiang, X., Kingery, J. R., Lewis, R. K., Li, Q., Rokosh, D. G., Ford, R., Spinale, F. G., Riggs, D. W., Srivastava, S., Bhatnagar, A., Bolli, R. & Prabhu, S. D., May 2010, In: Circulation. 121, 17, p. 1912-1925 14 p.Research output: Contribution to journal › Article › peer-review
Open Access211 Scopus citations -
Chronic AMD3100 antagonism of SDF-1α-CXCR4 exacerbates cardiac dysfunction and remodeling after myocardial infarction
Dai, S., Yuan, F., Mu, J., Li, C., Chen, N., Guo, S., Kingery, J., Prabhu, S. D., Bolli, R. & Rokosh, G., Oct 2010, In: Journal of Molecular and Cellular Cardiology. 49, 4, p. 587-597 11 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
Hepatocyte growth factor/met gene transfer in cardiac stem cells-potential for cardiac repair
Madonna, R., Rokosh, G., De Caterina, R. & Bolli, R., Jul 2010, In: Basic Research in Cardiology. 105, 4, p. 443-452 10 p.Research output: Contribution to journal › Review article › peer-review
53 Scopus citations -
Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction
Tang, X. L., Rokosh, G., Sanganalmath, S. K., Yuan, F., Sato, H., Mu, J., Dai, S., Li, C., Chen, N., Peng, Y., Dawn, B., Hunt, G., Leri, A., Kajstura, J., Tiwari, S., Shirk, G., Anversa, P. & Bolli, R., Jan 2010, In: Circulation. 121, 2, p. 293-305 13 p.Research output: Contribution to journal › Article › peer-review
Open Access346 Scopus citations -
Late-breaking basic science abstracts from the American Heart Association's Scientific Sessions 2010
Bolli, R., Chugh, A. R., D'Amario, D., Stoddard, M. F., Ikram, S., Wagner, S. G., Beache, G. M., Leri, A., Hosoda, T., Loughran, J. H., Goihberg, P., Fiorini, C., Solankhi, N. K., Fahsah, I., Chatterjee, A., Elmore, J. B., Rokosh, D. G., Slaughter, M. S., Kajstura, J. & Anversa, P., Dec 10 2010, In: Circulation research. 107, 12, p. e32-e40Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2009
Cell therapy for ischaemic heart disease: Focus on the role of resident cardiac stem cells
Chamuleau, S. A. J., Vrijsen, K. R., Rokosh, D. G., Tang, X. L., Piek, J. J. & Bolli, R., May 2009, In: Netherlands Heart Journal. 17, 5, p. 199-207 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access62 Scopus citations -
Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-κb-dependent pathway
Li, Q., Guo, Y., Ou, Q., Cui, C., Wu, W. J., Tan, W., Zhu, X., Lanceta, L. B., Sanganalmath, S. K., Dawn, B., Shinmura, K., Rokosh, G. D., Wang, S. & Bolli, R., Sep 2009, In: Circulation. 120, 13, p. 1222-1230 9 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
2008
Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition
West, M. B., Rokosh, G., Obal, D., Velayutham, M., Xuan, Y. T., Hill, B. G., Keith, R. J., Schrader, J., Guo, Y., Conklin, D. J., Prabhu, S. D., Zweier, J. L., Bolli, R. & Bhatnagar, A., Nov 4 2008, In: Circulation. 118, 19, p. 1970-1978 9 p.Research output: Contribution to journal › Article › peer-review
Open Access103 Scopus citations -
Heme-Egr-1: New partners in atherosclerotic progression?
Rokosh, G., Jan 2008, In: Circulation research. 102, 1, p. 6-8 3 p.Research output: Contribution to journal › Editorial
Open Access3 Scopus citations -
2007
Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase Cε-p44/42 mitogen-activated protein kinase-pSer-signal transducers and activators of transcription1/3 pathway
Xuan, Y. T., Guo, Y., Zhu, Y., Wang, O. L., Rokosh, G. & Bolli, R., Jul 2007, In: Circulation. 116, 5, p. 535-544 10 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
Methods in Molecular Biology: Preface
Zhang, J. & Rokosh, G., Mar 19 2007, Cardiac Gene Expression: Methods and Protocols. Zhang, J. & Rokosh, G. (eds.). p. v-vi (Methods in Molecular Biology; vol. 366).Research output: Chapter in Book/Report/Conference proceeding › Foreword/postscript
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Stromal cell-derived factor-1α confers protection against myocardial ischemia/reperfusion injury: Role of the cardiac stromal cell-derived factor-1α-CXCR4 axis
Hu, X., Dai, S., Wu, W. J., Tan, W., Zhu, X., Mu, J., Guo, Y., Bolli, R. & Rokosh, G., Aug 2007, In: Circulation. 116, 6, p. 654-663 10 p.Research output: Contribution to journal › Article › peer-review
Open Access287 Scopus citations -
The cardioprotection of the late phase of ischemic preconditioning is enhanced by postconditioning via a COX-2-mediated mechanism in conscious rats
Sato, H., Bolli, R., Rokosh, G. D., Bi, Q., Dai, S., Shirk, G. & Tang, X. L., Oct 2007, In: American Journal of Physiology - Heart and Circulatory Physiology. 293, 4, p. H2557-H2564Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations