Personal profile
Research interests
The focus of Dr. Yablonskiy’s research is in developing new quantitative MRI-based methods for in vivo studying of humans and animals in health and disease. Recent work is focused on applying these MRI techniques to link brain genetic and cellular microstructure with brain functioning. We study patients with Alzheimer disease, multiple sclerosis, traumatic brain injury and different psychiatric diseases.
For Alzheimer disease (AD), our methods allow in vivo identification of AD-related tissue cellular damage at the preclinical stage of AD, thus providing a new biomarker for screening population for early detection of AD pathology and in clinical drug trials. In multiple sclerosis (MS) our methods allow identification not only MS lesions, but also brain tissue damage in normal appearing gray matter and white matter that is not visible with standard clinical MRI
Clinical interests
Alzheimer disease, Multiple Sclerosis, Diseases of Central Nervous System
Available to Mentor:
- Undergraduate Students
- PhD Students
- Postdocs
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Collaborations and top research areas from the last five years
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AI-Powered Gradient Echo Plural Contrast Imaging (AI-GEPCI)—A Comprehensive Neurological Protocol From a Single MRI Scan
Lewis, J., Goyal, M. S., Wu, G. F., Hu, Y., Sukstanskii, A. L., Kothapalli, S. V. V. N., Cross, A. H., Kamilov, U. & Yablonskiy, D. A., 2026, (Accepted/In press) In: Journal of Magnetic Resonance Imaging.Research output: Contribution to journal › Article › peer-review
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Modeling of Fiber Orientation-Dependent R1 Relaxation in Human White Matter In Vivo Within The Framework of The Transient Hydrogen Bond Model
Yablonskiy, D. A., Kauppinen, R. A., Paasonen, E., Thotland, J., Könönen, M., Pisharady, P., Lenglet, C., Hakumäki, J. M., Gröhn, O. H. J., Garwood, M. & Sukstanskii, A. L., Jul 2026, In: Magnetic resonance in medicine. 96, 1, p. 315-322 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Novel insights into early Alzheimer's disease: quantitative gradient recalled echo MRI reveals preatrophic neuronal and myelin injury concurrent with emerging amyloid pathology
Kothapalli, S. V. V. N., Benzinger, T. L. S., Bateman, R. J., Li, M., Eldeniz, C., Morris, J. C. & Yablonskiy, D. A., Apr 1 2026, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 18, 2, e70355.Research output: Contribution to journal › Article › peer-review
Open Access -
Claustrum Volume Is Reduced in Multiple Sclerosis and Predicts Disability
Shelley, N., Judge, B., Yablonskiy, D. A., Naismith, R. T., Brier, M. R. & Cross, A. H., Jun 2025, In: Annals of Clinical and Translational Neurology. 12, 6, p. 1100-1108 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
CoRRECT: A Deep Unfolding Framework for Motion-Corrected Quantitative R2* Mapping
Xu, X., Gan, W., Kothapalli, S. V. V. N., Yablonskiy, D. A. & Kamilov, U. S., Apr 2025, In: Journal of Mathematical Imaging and Vision. 67, 2, 20.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations