Research Output per year
Research Output per year
Personal profile
Research interests
LMNA encodes Lamin A and C that, with B-type lamins, forms a nuclear meshwork underneath the inner nuclear membrane of the nuclear envelope. To date, over 200 mutations of LMNA are involved in more than 10 human pathologies involving clinically distinct or combined pathologies of muscle, nerve and bone as well as premature aging. The molecular etiology of these diseases as well as how mutations of a single gene encompass such a wide array of clinical presentations is still obscure. We are currently analyzing the phenotypical effect of some of these mutations in cultured cells.
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Research Output
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Mislocalization of cone nuclei impairs cone function in mice
Xue, Y., Razafsky, D., Hodzic, D. & Kefalov, V. J., Aug 1 2020, In : FASEB Journal. 34, 8, p. 10242-10249 8 p.Research output: Contribution to journal › Article
Open Access -
Analysis of High Molecular Weight Isoforms of Nesprin-1 and Nesprin-2 with Vertical Agarose Gel Electrophoresis
Potter, C. & Hodzic, D., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 25-33 9 p. (Methods in Molecular Biology; vol. 1840).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome
Kim, P. H., Luu, J., Heizer, P., Tu, Y., Weston, T. A., Chen, N., Lim, C., Li, R. L., Lin, P. Y., Dunn, J. C. Y., Hodzic, D., Young, S. G. & Fong, L. G., Sep 26 2018, In : Science translational medicine. 10, 460, eaat7163.Research output: Contribution to journal › Article
19 Scopus citations -
The KASH-containing isoform of Nesprin1 giant associates with ciliary rootlets of ependymal cells
Potter, C., Razafsky, D., Wozniak, D., Casey, M., Penrose, S., Ge, X., Mahjoub, M. R. & Hodzic, D., Jul 2018, In : Neurobiology of Disease. 115, p. 82-91 10 p.Research output: Contribution to journal › Article
1 Scopus citations -
Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets
Potter, C., Zhu, W., Razafsky, D., Ruzycki, P., Kolesnikov, A. V., Doggett, T., Kefalov, V. J., Betleja, E., Mahjoub, M. R. & Hodzic, D., Jul 10 2017, In : Current Biology. 27, 13, p. 2014-2022.e6Research output: Contribution to journal › Article
Open Access9 Scopus citations