Dennis Hallahan

2007

A study on adaptive IMRT treatment planning using kV cone-beam CT

Ding, G. X., Duggan, D. M., Coffey, C. W., Deeley, M., Hallahan, D. E., Cmelak, A. & Malcolm, A., Oct 2007, In: Radiotherapy and Oncology. 85, 1, p. 116-125 10 p.

Research output: Contribution to journal › Article › peer-review

171 Scopus citations

Deep-inspiration breath-hold kilovoltage cone-beam CT for setup of stereotactic body radiation therapy for lung tumors: Initial experience

Duggan, D. M., Ding, G. X., Coffey, C. W., Kirby, W., Hallahan, D. E., Malcolm, A. & Lu, B., Apr 2007, In: Lung Cancer. 56, 1, p. 77-88 12 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Facile production of multivalent enzyme-nanoparticle conjugates

Kuhn, S. J., Finch, S. K., Hallahan, D. E. & Giorgio, T. D., Apr 2007, In: Journal of Magnetism and Magnetic Materials. 311, 1 SPEC. ISS., p. 68-72 5 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Hedgehog signaling in the murine melanoma microenvironment

Geng, L., Cuneo, K. C., Cooper, M. K., Wang, H., Sekhar, K., Fu, A. & Hallahan, D. E., Dec 2007, In: Angiogenesis. 10, 4, p. 259-267 9 p.

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Histone deacetylase inhibitor NVP-LAQ824 sensitizes human nonsmall cell lung cancer to the cytotoxic effects of ionizing radiation

Cuneo, K. C., Fu, A., Osusky, K., Huamani, J., Hallahan, D. E. & Geng, L., Aug 2007, In: Anti-Cancer Drugs. 18, 7, p. 793-800 8 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

HIV protease inhibitors enhance the efficacy of irradiation

Cuneo, K. C., Tu, T., Geng, L., Fu, A., Hallahan, D. E. & Willey, C. D., May 15 2007, In: Cancer research. 67, 10, p. 4886-4893 8 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Impact of inhomogeneity corrections on dose coverage in the treatment of lung cancer using stereotactic body radiation therapy

Ding, G. X., Duggan, D. M., Lu, B., Hallahan, D. E., Cmelak, A., Malcolm, A., Newton, J., Deeley, M. & Coffey, C. W., 2007, In: Medical physics. 34, 7, p. 2985-2994 10 p.

Research output: Contribution to journal › Article › peer-review

84 Scopus citations

Measuring tumor perfusion in control and treated murine tumors: Correlation of microbubble contrast-enhanced sonography to dynamic contrast-enhanced magnetic resonance imaging and fluorodeoxyglucose positron emission tomography

Niermann, K. J., Fleischer, A. C., Huamani, J., Yankeelov, T. E., Kim, D. W., Wilson, W. D. & Hallahan, D. E., Jun 2007, In: Journal of Ultrasound in Medicine. 26, 6, p. 749-756 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography

Lyshchik, A., Fleischer, A. C., Huamani, J., Hallahan, D. E., Brissova, M. & Gore, J. C., Nov 2007, In: Journal of Ultrasound in Medicine. 26, 11, p. 1575-1586 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

119 Scopus citations

PDGFR-Β expression in small cell lung cancer patients

Shinohara, E. T., Gonzalez, A., Massion, P. P., Olson, S. J., Albert, J. M., Shyr, Y., Carbone, D. P., Johnson, D. H., Hallahan, D. E. & Lu, B., Feb 1 2007, In: International Journal of Radiation Oncology Biology Physics. 67, 2, p. 431-437 7 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

2006

Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling

Kwang, W. K., Mutter, R. W., Cao, C., Albert, J. M., Freeman, M., Hallahan, D. E. & Lu, B., Dec 1 2006, In: Journal of Biological Chemistry. 281, 48, p. 36883-36890 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

169 Scopus citations

Characterization of superparamagnetic nanoparticle interactions with extracellular matrix in an in vitro system

Kuhn, S. J., Hallahan, D. E. & Giorgio, T. D., Jan 2006, In: Annals of biomedical engineering. 34, 1, p. 51-58 8 p.

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining

Zhuang, J., Zhang, J., Willers, H., Wang, H., Chung, J. H., Van Gent, D. C., Hallahan, D. E., Powell, S. N. & Xia, F., Feb 1 2006, In: Cancer research. 66, 3, p. 1401-1408 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

98 Scopus citations

Correlation between estimates of tumor perfusion from microbubble contrast-enhanced sonography and dynamic contrast-enhanced magnetic resonance imaging

Yankeelov, T. E., Niermann, K. J., Huamani, J., Kim, D. W., Quarles, C. C., Fleischer, A. C., Hallahan, D. E., Price, R. R. & Gore, J. C., Apr 2006, In: Journal of Ultrasound in Medicine. 25, 4, p. 487-497 11 p.

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Histone deacetylase (HDAC) inhibitor LBH589 increases duration of γ-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer

Geng, L., Cuneo, K. C., Fu, A., Tu, T., Atadja, P. W. & Hallahan, D. E., Dec 1 2006, In: Cancer research. 66, 23, p. 11298-11304 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

163 Scopus citations

Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas

Stacy, D. R., Ely, K., Massion, P. P., Yarbrough, W. G., Hallahan, D. E., Sekhar, K. R. & Freeman, M. L., Sep 2006, In: Head and Neck. 28, 9, p. 813-818 6 p.

Research output: Contribution to journal › Article › peer-review

128 Scopus citations

Integrin α_vβ₃ antagonist Cilengitide enhances efficacy of radiotherapy in endothelial cell and non-small-cell lung cancer models

Albert, J. M., Cao, C., Geng, L., Leavitt, L., Hallahan, D. E. & Lu, B., Aug 1 2006, In: International Journal of Radiation Oncology Biology Physics. 65, 5, p. 1536-1543 8 p.

Research output: Contribution to journal › Article › peer-review

122 Scopus citations

Lithium treatment prevents neurocognitive deficit resulting from cranial irradiation

Yazlovitskaya, E. M., Edwards, E., Thotala, D., Fu, A., Osusky, K. L., Whetsell, W. O., Boone, B., Shinohara, E. T. & Hallahan, D. E., Dec 1 2006, In: Cancer research. 66, 23, p. 11179-11186 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

155 Scopus citations

Molecular strategies targeting the host component of cancer to enhance tumor response to radiation therapy

Kim, D. W., Huamani, J., Fu, A. & Hallahan, D. E., Jan 1 2006, In: International Journal of Radiation Oncology Biology Physics. 64, 1, p. 38-46 9 p.

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Noninvasive assessment of tumor vasculature response to radiation-mediated, vasculature-targeted therapy using quantified power Doppler sonography: Implications for improvement of therapy schedules

Kim, D. W. N., Huamani, J., Niermann, K. J., Lee, H., Geng, L., Leavitt, L. L., Baheza, R. A., Jones, C. C., Tumkur, S., Yankeelov, T. E., Fleischer, A. C. & Hallahan, D. E., Dec 2006, In: Journal of Ultrasound in Medicine. 25, 12, p. 1507-1517 11 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Protein kinase B/Akt-dependent phosphorylation of glycogen synthase kinase-3β in irradiated vascular endothelium

Tan, J., Geng, L., Yazlovitskaya, E. M. & Hallahan, D. E., Feb 15 2006, In: Cancer research. 66, 4, p. 2320-2327 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

Proteolytic surface functionalization enhances in vitro magnetic nanoparticle mobility through extracellular matrix

Kuhn, S. J., Finch, S. K., Hallahan, D. E. & Giorgio, T. D., Feb 2006, In: Nano Letters. 6, 2, p. 306-312 7 p.

Research output: Contribution to journal › Article › peer-review

84 Scopus citations

Radiation-guided gene therapy of cancer

Han, Z., Wang, H. & Hallahan, D. E., Aug 2006, In: Technology in Cancer Research and Treatment. 5, 4, p. 437-443 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

9 Scopus citations

Radiosensitization of lung cancer by nutlin, an inhibitor of murine double minute 2

Cao, C., Shinohara, E. T., Subhawong, T. K., Geng, L., Kim, K. W., Albert, J. M., Hallahan, D. E. & Lu, B., Feb 2006, In: Molecular Cancer Therapeutics. 5, 2, p. 411-417 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

76 Scopus citations

SRC family kinase inhibitor SU6656 enhances antiangiogenic effect of irradiation

Cuneo, K. C., Geng, L., Tan, J., Brousal, J., Shinohara, E. T., Osusky, K., Fu, A., Shyr, Y., Wu, H. & Hallahan, D. E., Mar 15 2006, In: International Journal of Radiation Oncology Biology Physics. 64, 4, p. 1197-1203 7 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

STI571 (Gleevec) improves tumor growth delay and survival in irradiated mouse models of glioblastoma

Geng, L., Shinohara, E. T., Kim, D., Tan, J., Osusky, K., Shyr, Y. & Hallahan, D. E., Jan 1 2006, In: International Journal of Radiation Oncology Biology Physics. 64, 1, p. 263-271 9 p.

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

SU‐FF‐J‐18: Adaptive IMRT Using Cone‐Beam CT: A Case Study On Patients with Bulky Head and Neck Tumors

Ding, G., Duggan, D., Coffey, C., Hallahan, D. & Deeley, M., Jun 2006, In: Medical physics. 33, 6, 1 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2005

DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs

Shinohara, E. T., Geng, L., Tan, J., Chen, H., Shir, Y., Edwards, E., Halbrook, J., Kesicki, E. A., Kashishian, A. & Hallahan, D. E., Jun 15 2005, In: Cancer research. 65, 12, p. 4987-4992 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

132 Scopus citations

Enhanced radiation damage of tumor vasculature by mTOR inhibitors

Shinohara, E. T., Cao, C., Niermann, K., Mu, Y., Zeng, F., Hallahan, D. E. & Lu, B., Aug 18 2005, In: Oncogene. 24, 35, p. 5414-5422 9 p.

Research output: Contribution to journal › Article › peer-review

176 Scopus citations

Inhibition of α_vβ₃ integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy

Abdollahi, A., Griggs, D. W., Zieher, H., Roth, A., Lipson, K. E., Saffrich, R., Gröne, H. J., Hallahan, D. E., Reisfeld, R. A., Debus, J., Niethammer, A. G. & Huber, P. E., Sep 1 2005, In: Clinical Cancer Research. 11, 17, p. 6270-6279 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

203 Scopus citations

Murine double minute 2 as a therapeutic target for radiation sensitization of lung cancer

Cao, C., Shinohara, E. T., Niermann, K. J., Donnelly, E. F., Chen, X., Hallahan, D. E. & Lu, B., Aug 2005, In: Molecular Cancer Therapeutics. 4, 8, p. 1137-1145 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma

Shinohara, E. T., Gonzalez, A., Massion, P. P., Chen, H., Li, M., Freyer, A. S., Olson, S. J., Andersen, J. J., Shyr, Y., Carbone, D. P., Johnson, D. H., Hallahan, D. E. & Lu, B., Apr 15 2005, In: Cancer. 103, 8, p. 1685-1692 8 p.

Research output: Contribution to journal › Article › peer-review

101 Scopus citations

Sonographic depiction of changes of tumor vascularity in response to various therapies

Niermann, K. J., Fleischer, A. C., Donnelly, E. F., Schueneman, A. J., Geng, L. & Hallahan, D. E., Jun 2005, In: Ultrasound Quarterly. 21, 2, p. 61-67 7 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

The use of tyrosine kinase inhibitors in modifying the response of tumor microvasculature to radiotherapy

Lu, B., Shinohara, E. T., Edwards, E., Geng, L., Tan, J. & Hallahan, D. E., Dec 2005, In: Technology in Cancer Research and Treatment. 4, 6, p. 691-698 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

16 Scopus citations

2004

Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway

DeBusk, L. M., Hallahan, D. E. & Lin, P. C., Aug 1 2004, In: Experimental Cell Research. 298, 1, p. 167-177 11 p.

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

A specific antagonist of the P110δ catalytic component of phospilatidylinositol 3′-kinase, IC486068, enhances radiation-induced tumor vascular destruction

Geng, L., Tan, J., Himmelfarb, E., Schueneman, A., Niermann, K., Fu, A., Cuneo, K., Kesicki, E. A., Treiberg, J., Haytlick, J. S. & Hallahan, D. E., Jul 15 2004, In: Cancer research. 64, 14, p. 4893-4899 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

Broad spectrum receptor tyrosine kinase inhibitor, SU6668, sensitizes radiation via targeting survival pathway of vascular endothelium

Lu, B., Geng, L., Musiek, A., Tan, J., Cao, C., Donnelly, E., McMahon, G., Choy, H. & Hallahan, D. E., Mar 2004, In: International Journal of Radiation Oncology Biology Physics. 58, 3, p. 844-850 7 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Erratum: A specific antagonist of the p110δ catalytic component of phosphatidylinositol 3′-kinase, IC486068, enhances radiation-induced tumor vascular destruction (Cancer Research (July 2004) 64 (4893-4899)

Geng, L., Tan, J., Himmelfarb, E., Schueneman, A., Niermann, K., Brousal, J., Fu, A., Cuneo, K., Kesicki, E. A., Treiberg, J., Hayflick, J. S. & Hallahan, D. E., Nov 1 2004, In: Cancer research. 64, 21, p. 8130 1 p.

Research output: Contribution to journal › Comment/debate

Erratum: XIAP and survivin as therapeutic targets for radiation sensitization in preclinical models of lung cancer (Oncogene (2004) 23 (7047-7052) doi:10.1038/sj.onc.1207929)

Cao, C., Mu, Y., Hallahan, D. E. & Lu, B., Dec 16 2004, In: Oncogene. 23, 58, 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

2 Scopus citations

Nuclear survivin as a biomarker for non-small-cell lung cancer

Lu, B., Gonzalez, A., Massion, P. P., Shyr, Y., Shaktour, B., Carbone, D. F. & Hallahan, D. E., Aug 2 2004, In: British Journal of Cancer. 91, 3, p. 537-540 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

Phantom validation of coregistration of PET and CT for image-guided radiotherapy

Lavely, W. C., Scarfone, C., Cevikalp, H., Li, R., Byrne, D. W., Cmelak, A. J., Dawant, B., Price, R. R., Hallahan, D. E. & Fitzpatrick, J. M., May 2004, In: Medical physics. 31, 5, p. 1083-1092 10 p.

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging

Scarfone, C., Lavely, W. C., Cmelak, A. J., Delbeke, D., Martin, W. H., Billheimer, D. & Hallahan, D. E., Apr 1 2004, In: Journal of Nuclear Medicine. 45, 4, p. 543-552 10 p.

Research output: Contribution to journal › Article › peer-review

177 Scopus citations

Quantification of Tumor Vascularity with Contrast-Enhanced Sonography: Correlation with Magnetic Resonance Imaging and Fluorodeoxyglucose Autoradiography in an Implanted Tumor

Fleischer, A. C., Donnelly, E. F., Grippo, R. J., Black, A. S. & Hallahan, D. E., Jan 2004, In: Journal of Ultrasound in Medicine. 23, 1, p. 37-41 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Radiation-guided drug delivery systems

Stacy, D. R., Lu, B. & Hallahan, D. E., Apr 2004, In: Expert Review of Anticancer Therapy. 4, 2, p. 283-288 6 p.

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Radiation-guided drug delivery to tumor blood vessels results in improved tumor growth delay

Geng, L., Osusky, K., Konjeti, S., Fu, A. & Hallahan, D., Oct 19 2004, In: Journal of Controlled Release. 99, 3, p. 369-381 13 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Receptor tyrosine kinase inhibitors as anti-angiogenic agents

Kim, D. W., Lu, B. & Hallahan, D. E., Jun 1 2004, In: Current Opinion in Investigational Drugs. 5, 6, p. 597-604 8 p.

Research output: Contribution to journal › Review article › peer-review

27 Scopus citations

Sonographic depiction of microvessel perfusion: Principles and potential

Fleischer, A. C., Niermann, K. J., Donnelly, E. F., Yankeelov, T. E., Canniff, K. M., Hallahan, D. E. & Rothenberg, M. E., Nov 2004, In: Journal of Ultrasound in Medicine. 23, 11, p. 1499-1506 8 p.

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Survivin As a Therapeutic Target for Radiation Sensitization in Lung Cancer

Lu, B., Mu, Y., Cao, C., Zeng, F., Schneider, S., Tan, J., Price, J., Chen, J., Freeman, M. & Hallahan, D. E., Apr 15 2004, In: Cancer research. 64, 8, p. 2840-2845 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

156 Scopus citations

The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels

Osusky, K. L., Hallahan, D. E., Fu, A., Ye, F., Shyr, Y. & Geng, L., Sep 2004, In: Angiogenesis. 7, 3, p. 225-233 9 p.

Research output: Contribution to journal › Article › peer-review

140 Scopus citations

The use of antisense oligonucleotides in evaluating survivin as a therapeutic target for radiation sensitization in lung cancer

Shinohara, E. T., Hallahan, D. E. & Lu, B., Oct 25 2004, In: Biological Procedures Online. 6, 1, p. 250-256 7 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Dennis Hallahan

Research output

Search results