Research output per year
Research output per year
Personal profile
Research interests
Research in the Goldfarb lab focuses on computational mass spectrometry, proteomics, and their applications in biology. His lab develops open-source solutions for novel data acquisition strategies, data analysis, and visualization tailored to the unique challenges of each experiment. Dr. Goldfarb aims to increase the throughput and reproducibility of large-scale projects with automated pipelines that leverage high-performance computing. Recently his research has concentrated on instrumentation, protein complex identification, and de novo peptide sequencing.
Available to Mentor:
- PhD/MSTP Students
- Postdocs
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Collaborations and top research areas from the last five years
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Proximity proteomics provides a new resource for exploring the function of Afadin and the complexity of cell-cell adherens junctions
Choi, W., Goldfarb, D., Yan, F., Major, M. B., Fanning, A. S. & Peifer, M., Feb 2025, In: Biology Open. 14, 2, bio061811.Research output: Contribution to journal › Article › peer-review
Open Access -
The gain-of-function UBE3AQ588E variant causes Angelman-like neurodevelopmental phenotypes in mice
Weston, K. P., Gunelson, A. M., Maloney, S., Ge, X., Stelzer, J. A., Kim, K. S., Collier, S., Mindt, M. M., Agajanian, M. J., Major, M. B., Goldfarb, D., Noguchi, K. & Yi, J., Dec 2025, In: Scientific reports. 15, 1, 9152.Research output: Contribution to journal › Article › peer-review
Open Access -
A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models
Puray-Chavez, M., Eschbach, J. E., Xia, M., LaPak, K. M., Zhou, Q., Jasuja, R., Pan, J., Xu, J., Zhou, Z., Mohammed, S., Wang, Q., Lawson, D. Q., Djokic, S., Hou, G., Ding, S., Brody, S. L., Major, M. B., Goldfarb, D. & Kutluay, S. B., Dec 2024, In: Nature communications. 15, 1, 8394.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Correction to: A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis (Nature Communications, (2016), 7, 1, (12105), 10.1038/ncomms12105)
Gao, Y., Mutter-Rottmayer, E., Greenwalt, A. M., Goldfarb, D., Yan, F., Yang, Y., Martinez-Chacin, R. C., Pearce, K. H., Tateishi, S., Major, M. B. & Vaziri, C., Dec 2024, In: Nature communications. 15, 1, 9854.Research output: Contribution to journal › Comment/debate
Open Access -
Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency
Chen, J., Su, S., Pickar-Oliver, A., Chiarella, A. M., Hahn, Q., Goldfarb, D., Cloer, E. W., Small, G. W., Sivashankar, S., Ramsden, D. A., Major, M. B., Hathaway, N. A., Gersbach, C. A. & Liu, P., Oct 28 2024, In: Nucleic acids research. 52, 19, p. 11536-11551 16 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations