Research output per year
Research output per year
Personal profile
Research interests
Research in the Goldfarb lab focuses on computational mass spectrometry, proteomics, and their applications in biology. His lab develops open-source solutions for novel data acquisition strategies, data analysis, and visualization tailored to the unique challenges of each experiment. Dr. Goldfarb aims to increase the throughput and reproducibility of large-scale projects with automated pipelines that leverage high-performance computing. Recently his research has concentrated on instrumentation, protein complex identification, and de novo peptide sequencing.
Available to Mentor:
- PhD/MSTP Students
- Postdocs
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Collaborations and top research areas from the last five years
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Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein
Mooren, O. L., Stuchell-Brereton, M. D., McConnell, P., Yan, C., Wilkerson, E. M., Goldfarb, D., Cooper, J., Sept, D. & Soranno, A., Dec 15 2023, In: Journal of Molecular Biology. 435, 24, 168342.Research output: Contribution to journal › Article › peer-review
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Structural basis of paralog-specific KDM2A/B nucleosome recognition
Spangler, C. J., Skrajna, A., Foley, C. A., Nguyen, A., Budziszewski, G. R., Azzam, D. N., Arteaga, E. C., Simmons, H. C., Smith, C. B., Wesley, N. A., Wilkerson, E. M., McPherson, J. M. E., Kireev, D., James, L. I., Frye, S. V., Goldfarb, D. & McGinty, R. K., May 2023, In: Nature Chemical Biology. 19, 5, p. 624-632 9 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract
Zhang, J., Walker, M. E., Sanidad, K. Z., Zhang, H., Liang, Y., Zhao, E., Chacon-Vargas, K., Yeliseyev, V., Parsonnet, J., Haggerty, T. D., Wang, G., Simpson, J. B., Jariwala, P. B., Beaty, V. V., Yang, J., Yang, H., Panigrahy, A., Minter, L. M., Kim, D., Gibbons, J. G., & 11 others, Dec 2022, In: Nature communications. 13, 1, 136.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling
Agajanian, M. J., Potjewyd, F. M., Bowman, B. M., Solomon, S., LaPak, K. M., Bhatt, D. P., Smith, J. L., Goldfarb, D., Axtman, A. D. & Major, M. B., Jun 2022, In: Journal of Biological Chemistry. 298, 6, 101986.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Erratum: Positive Cooperativity in Substrate Binding by Human Thymidylate Synthase (Biophysical Journal (2019) 117(6) (1074–1084), (S0006349519307106), (10.1016/j.bpj.2019.08.015))
Bonin, J. P., Sapienza, P. J., Wilkerson, E., Goldfarb, D., Wang, L., Herring, L., Chen, X., Major, M. B. & Lee, A. L., Sep 21 2021, In: Biophysical Journal. 120, 18, p. 4137 1 p.Research output: Contribution to journal › Comment/debate
Open Access