Research output per year
Research output per year
Personal profile
Research interests
Type I interferons are a class of cytokines that regulate numerous biological pathways, including the induction of a host antiviral state, regulation of apoptosis, inhibition of cell growth, and modulation of both the innate and adaptive immune responses. Interferons mediate these activities through the induction of hundred of gene products known as interferon stimulated genes (ISGs). We are interested in identifying novel ISGs that function to modulate the host anti-viral response, the innate and adaptive immune response, and their role in the development of autoimmunity.
Clinical interests
Rheumatology
Available to Mentor:
- PhD/MSTP Students
Fingerprint
Dive into the research topics where Deborah Lenschow is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Initiator cell death event induced by SARS-CoV-2 in the human airway epithelium
Liang, K., Barnett, K. C., Hsu, M., Chou, W. C., Bais, S. S., Riebe, K., Xie, Y., Nguyen, T. T., Oguin, T. H., Vannella, K. M., Hewitt, S. M., Chertow, D. S., Blasi, M., Sempowski, G. D., Karlsson, A., Koller, B. H., Lenschow, D. J., Randell, S. H. & Ting, J. P. Y., 2024, In: Science immunology. 9, 97, eadn0178.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
En garde! The duel functions of MORC3
Fox, L. E. & Lenschow, D. J., Jan 12 2022, In: Cell host & microbe. 30, 1, p. 8-9 2 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis
Hiller, B. E., Yin, Y., Perng, Y. C., de Araujo Castro, Í., Fox, L. E., Locke, M. C., Monte, K. J., López, C. B., Ornitz, D. M. & Lenschow, D. J., Jun 2022, In: PLoS pathogens. 18, 6, e1010228.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Interferon Alpha, but Not Interferon Beta, Acts Early To Control Chronic Chikungunya Virus Pathogenesis
Locke, M. C., Fox, L. E., Dunlap, B. F., Young, A. R., Monte, K. & Lenschow, D. J., Jan 2022, In: Journal of virology. 96, 1, e01143-21.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro
Swaim, C. D., Dwivedi, V., Perng, Y. C., Zhao, X., Canadeo, L. A., Harastani, H. H., Darling, T. L., Boon, A. C. M., Lenschow, D. J., Kulkarni, V. & Huibregtse, J. M., Oct 22 2021, In: iScience. 24, 10, 103213.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations