Research output per year
Research output per year
Personal profile
Research interests
My lab studies the genomics and epigenomics of AML, with an emphasis on how AML mutations alter the epigenome and gene expression. I am also interested in developing genomic methods for diagnosis and disease monitoring in AML patients.
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Clinical whole-genome sequencing in cancer diagnosis
Hou, Y. C. C., Neidich, J. A., Duncavage, E. J., Spencer, D. & Schroeder, M., 2022, (Accepted/In press) In: Human mutation.Research output: Contribution to journal › Review article › peer-review
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DNMT3A overgrowth syndrome is associated with the development of hematopoietic malignancies in children and young adults
Ferris, M. A., Smith, A. M., Heath, S. E., Duncavage, E. J., Oberley, M., Freyer, D., Wynn, R., Douzgou, S., Maris, J. M., Reilly, A. F., Wu, M. D., Choo, F., Fiets, R. B., Koene, S., Spencer, D. H., Miller, C. A., Shinawi, M. & Ley, T. J., Jan 20 2022, In: Blood. 139, 3, p. 461-464 4 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence
Miller, C. A., Walker, J. R., Jensen, T. L., Hooper, W. F., Fulton, R. S., Painter, J. S., Sekeres, M. A., Ley, T. J., Spencer, D. H., Goll, J. B. & Walter, M. J., Mar 2022, In: Journal of Molecular Diagnostics. 24, 3, p. 219-223 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells
Wilson, E. R., Helton, N. M., Heath, S. E., Fulton, R., Payton, J. E., Welch, J., Walter, M., Westervelt, P., DiPersio, J. F., Link, D. C., Miller, C., Ley, T. J. & Spencer, D., Apr 2022, In: Leukemia. 36, 4, p. 935-945 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia
Berrien-Elliott, M. M., Foltz, J. A., Russler-Germain, D. A., Neal, C. C., Tran, J., Gang, M., Wong, P., Fisk, B., Cubitt, C. C., Marin, N. D., Zhou, A. Y., Jacobs, M. T., Foster, M., Schappe, T., McClain, E., Kersting-Schadek, S., Desai, S., Pence, P., Becker-Hapak, M., Eisele, J. & 20 others, , Feb 23 2022, In: Science translational medicine. 14, 633, abm1375.Research output: Contribution to journal › Article › peer-review