Research Output per year
Research Output per year
Personal profile
Research interests
My lab studies the genomics and epigenomics of AML, with an emphasis on how AML mutations alter the epigenome and gene expression. I am also interested in developing genomic methods for diagnosis and disease monitoring in AML patients.
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Research Output
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Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells
Ghasemi, R., Struthers, H., Wilson, E. R. & Spencer, D. H., Jan 1 2020, (Accepted/In press) In: Leukemia.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Deletions in BCP-ALL result in a TAD more FLT3
Spencer, D. H., Aug 20 2020, In: Blood. 136, 8, p. 919-920 2 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing
Ketkar, S., Verdoni, A. M., Smith, A. M., Bangert, C. V., Leight, E. R., Chen, D. Y., Brune, M. K., Helton, N. M., Hoock, M., George, D. R., Fronick, C., Fulton, R. S., Ramakrishnan, S. M., Chang, G. S., Petti, A. A., Spencer, D. H., Miller, C. A. & Ley, T. J., Feb 11 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 6, p. 3123-3134 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
Linette, G. P., Becker-Hapak, M., Skidmore, Z. L., Baroja, M. L., Xu, C., Hundal, J., Spencer, D. H., Fu, W., Cummins, C., Robnett, M., Kaabinejadian, S., Hildebrand, W. H., Magrini, V., Demeter, R., Krupnick, A. S., Griffith, O. L., Griffith, M., Mardis, E. R. & Carreno, B. M., Nov 19 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 47, p. 23662-23670 9 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Inflammatory cytokines promote clonal hematopoiesis with specific mutations in ulcerative colitis patients
Zhang, C. R. C., Nix, D., Gregory, M., Ciorba, M. A., Ostrander, E. L., Newberry, R. D., Spencer, D. H. & Challen, G. A., Dec 2019, In: Experimental Hematology. 80, p. 36-41.e3Research output: Contribution to journal › Article › peer-review
12 Scopus citations