Research output per year
Research output per year
Personal profile
Research interests
My lab studies the genomics and epigenomics of AML, with an emphasis on how AML mutations alter the epigenome and gene expression. I am also interested in developing genomic methods for diagnosis and disease monitoring in AML patients.
Fingerprint
Dive into the research topics where David Spencer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Clinical whole-genome sequencing in cancer diagnosis
Hou, Y. C. C., Neidich, J. A., Duncavage, E. J., Spencer, D. H. & Schroeder, M. C., Nov 2022, In: Human mutation. 43, 11, p. 1519-1530 12 p.Research output: Contribution to journal › Review article › peer-review
-
Clonal dynamics of haematopoiesis across the human lifespan
Mitchell, E., Spencer Chapman, M., Williams, N., Dawson, K. J., Mende, N., Calderbank, E. F., Jung, H., Mitchell, T., Coorens, T. H. H., Spencer, D. H., Machado, H., Lee-Six, H., Davies, M., Hayler, D., Fabre, M. A., Mahbubani, K., Abascal, F., Cagan, A., Vassiliou, G. S., Baxter, J., & 9 others, Jun 9 2022, In: Nature. 606, 7913, p. 343-350 8 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
DNMT3A overgrowth syndrome is associated with the development of hematopoietic malignancies in children and young adults
Ferris, M. A., Smith, A. M., Heath, S. E., Duncavage, E. J., Oberley, M., Freyer, D., Wynn, R., Douzgou, S., Maris, J. M., Reilly, A. F., Wu, M. D., Choo, F., Fiets, R. B., Koene, S., Spencer, D. H., Miller, C. A., Shinawi, M. & Ley, T. J., Jan 20 2022, In: Blood. 139, 3, p. 461-464 4 p.Research output: Contribution to journal › Letter › peer-review
Open Access2 Scopus citations -
Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence
Miller, C. A., Walker, J. R., Jensen, T. L., Hooper, W. F., Fulton, R. S., Painter, J. S., Sekeres, M. A., Ley, T. J., Spencer, D. H., Goll, J. B. & Walter, M. J., Mar 2022, In: Journal of Molecular Diagnostics. 24, 3, p. 219-223 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells
Wilson, E. R., Helton, N. M., Heath, S. E., Fulton, R., Payton, J. E., Welch, J., Walter, M., Westervelt, P., DiPersio, J. F., Link, D. C., Miller, C., Ley, T. J. & Spencer, D., Apr 2022, In: Leukemia. 36, 4, p. 935-945 11 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations