Research output per year
Research output per year
Personal profile
Research interests
Our lab focuses on the pathogenesis and host response to Klebsiella pneumoniae, an increasingly resistant and versatile organism. One of only three threats deemed "urgent" by the CDC, resistant Klebsiella infections kill half of people afflicted and are only increasing in prevalence. Utilizing mouse models of pneumonia, bacteremia and urinary tract infection (UTI), we are dissecting just how this bacterium causes infection in the host and how the host responds. We are particularly interested in adaptive responses to Klebsiella pneumoniae including the development of broad and effective vaccines.
Clinical interests
Pediatric infectious diseases, resistant bacterial infections
Mentoring
Excited to host trainees in my Klebsiella pathogenesis lab. Please contact me directly to hear more about potential projects.
Available to Mentor:
- Undergraduate Students
- PhD/MSTP Students
- Postdocs
- Residents and Fellows
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Airway multidrug-resistant organisms in a population of tracheostomy and chronic ventilator-dependent children at a tertiary care pediatric hospital
Havens, T. N., Rosen, D. A. & Rivera-Spoljaric, K., Jan 2023, In: Pediatric Pulmonology. 58, 1, p. 26-34 9 p.Research output: Contribution to journal › Article › peer-review
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Discovery and characterization of a new class of O-linking oligosaccharyltransferases from the Moraxellaceae family
Knoot, C. J., Wantuch, P. L., Robinson, L. S., Rosen, D. A., Scott, N. E. & Harding, C. M., Jan 8 2023, In: Glycobiology. 33, 1, p. 57-74 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Classical and γδ T cells are each independently sufficient to establish protection against a classical strain of Klebsiella pneumoniae
Mackel, J. J., Morffy Smith, C., Wasbotten, R. K., Twentyman, J. & Rosen, D. A., Aug 31 2022, In: Frontiers in cellular and infection microbiology. 12, 974175.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Murine Respiratory Tract Infection with Classical Klebsiella pneumoniae Induces Bronchus-Associated Lymphoid Tissue
Wasbotten, R. K., Dahler, A. A., Mackel, J. J., Smith, C. M. & Rosen, D. A., Apr 2022, In: Infection and immunity. 90, 4Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Skin Findings of Impetigo Neonatorum and Staphylococcal Scalded Skin Syndrome
Daniels, E. A. & Rosen, D. A., Dec 2022, In: Journal of Pediatrics. 251, p. 216-217 2 p.Research output: Contribution to journal › Article › peer-review
Open Access