Our lab is dedicated to understanding the complex interplay between immune responses and the tumor microenvironment, focusing on how these factors both shape and are shaped by tumor progression and the response to anti-cancer therapies. We strive to identify key vulnerabilities within this dynamic system and harness them to improve patient outcomes, particularly by enhancing the efficacy of conventional treatments and immunotherapies. 

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The DeNardo Lab is dedicated to training the next generation of scientists and cancer researchers. As such, our group welcomes all individuals, regardless of physical ability, gender, sexual orientation, age, race/ethnicity, religion, or cultural background.
We are a team of scientists with diverse backgrounds and experiences, who have created a nurturing and inclusive environment that fosters a sense of belonging. United by a common goal—to fight cancer through research—we measure our success not only by the discoveries we make but also by the community we build to achieve them. Additionally, we take pride in the career and personal growth of each individual involved in our research as they progress through their training journey within our team.