David Clifford

2005

Clinical validation of the NeuroScreen

Ellis, R. J., Evans, S. R., Clifford, D. B., Moo, L. R., McArthur, J. C., Collier, A. C., Benson, C., Bosch, R., Simpson, D., Yiannoutsos, C. T., Yang, Y. & Robertson, K., Dec 1 2005, In: Journal of NeuroVirology. 11, 6, p. 503-511 9 p.

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Genotyping of Toxoplasma gondii strains from immunocompromised patients reveals high prevalence of type I strains

Khan, A., Su, C., German, M., Storch, G. A., Clifford, D. B. & Sibley, L. D., Dec 2005, In: Journal of clinical microbiology. 43, 12, p. 5881-5887 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

183 Scopus citations

Impact of efavirenz on neuropsychological performance and symptoms in HIV-infected individuals

Clifford, D. B., Evans, S., Yang, Y., Acosta, E. P., Goodkin, K., Tashima, K., Simpson, D., Dorfman, D., Ribaudo, H. & Gulick, R. M., Nov 15 2005, In: Annals of internal medicine. 143, 10, p. 714-721+I43

Research output: Contribution to journal › Article › peer-review

235 Scopus citations

Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: An adult AIDS clinical trials group study

Hulgan, T., Haas, D. W., Haines, J. L., Ritchie, M. D., Robbins, G. K., Shafer, R. W., Clifford, D. B., Kallianpur, A. R., Summar, M. & Canter, J. A., Sep 2 2005, In: AIDS. 19, 13, p. 1341-1349 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

127 Scopus citations

Neurologic consequences of hepatitis C and human immunodeficiency virus coinfection

Clifford, D. B., Yang, Y. & Evans, S., 2005, In: Journal of NeuroVirology. 11, SUPPL. 3, p. 67-71 5 p.

Research output: Contribution to journal › Review article › peer-review

27 Scopus citations

Pharmacogenetics of long-term responses to antiretroviral regimens containing efavirenz and/or nelfinavir: An adult AIDS clinical trials group study

Haas, D. W., Smeaton, L. M., Shafer, R. W., Robbins, G. K., Morse, G. D., Labbé, L., Wilkinson, G. R., Clifford, D. B., D'Aquila, R. T., De Gruttola, V., Pollard, R. B., Merigan, T. C., Hirsch, M. S., George, A. L., Donahue, J. P. & Kim, R. B., Dec 1 2005, In: Journal of Infectious Diseases. 192, 11, p. 1931-1942 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

233 Scopus citations

The neuropsychological and neurological impact of hepatitis C virus co-infection in HIV-infected subjects

Clifford, D. B., Evans, S. R., Yang, Y. & Gulick, R. M., Oct 2005, In: AIDS. 19, SUPPL. 3, p. S64-S71

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Undetectable cerebrospinal fluid HIV RNA and β-2 microglobulin do not indicate inactive AIDS dementia complex in highly active antiretroviral therapy-treated patients

Cysique, L. A., Brew, B. J., Halman, M., Catalan, J., Sacktor, N., Price, R. W., Brown, S., Atkinson, J. H., Clifford, D. B., Simpson, D., Torres, G., Hall, C., Power, C., Marder, K., McArthur, J. C., Symonds, W. & Romero, C., Aug 1 2005, In: Journal of Acquired Immune Deficiency Syndromes. 39, 4, p. 426-429 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

55 Scopus citations

2006

Cytotoxic T cell recognition of an HIV-1 reverse transcriptase variant peptide incorporating the K103N drug resistance mutation

Mahnke, L. & Clifford, D., Sep 14 2006, In: AIDS Research and Therapy. 3, 1, 21.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Dr. Yousry and colleagues reply [5]

Major, E. O., Yousry, T. A. & Clifford, D. B., Jun 1 2006, In: New England Journal of Medicine. 354, 22, p. 2388-2389 2 p.

Research output: Contribution to journal › Letter › peer-review

1 Scopus citations

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

Yousry, T. A., Major, E. O., Ryschkewitsch, C., Fahle, G., Fischer, S., Hou, J., Curfman, B., Miszkiel, K., Mueller-Lenke, N., Sanchez, E., Barkhof, F., Radue, E. W., Jäger, H. R. & Clifford, D. B., Mar 2 2006, In: New England Journal of Medicine. 354, 9, p. 924-933 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

721 Scopus citations

Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy

Kallianpur, A. R., Hulgan, T., Canter, J. A., Ritchie, M. D., Haines, J. L., Robbins, G. K., Shafer, R. W., Clifford, D. B. & Haas, D. W., Jul 2006, In: AIDS. 20, 11, p. 1503-1513 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

HIV-Associated Dementia

Clifford, D. B. & Gould, M., Jan 1 2006, Handbook of Dementing Illnesses, Second Edition. CRC Press, p. 321-331 11 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

HIV neuropathy natural history cohort study: Assessment measures and risk factors

Simpson, D. M., Kitch, D., Evans, S. R., McArthur, J. C., Asmuth, D. M., Cohen, B., Goodkin, K., Gerschenson, M., So, Y., Marra, C. M., Diaz-Arrastia, R., Shriver, S., Millar, L. & Clifford, D. B., Jun 2006, In: Neurology. 66, 11, p. 1679-1687 9 p.

Research output: Contribution to journal › Article › peer-review

150 Scopus citations

Multilocus genetic interactions and response to efavirenz-containing regimens: An Adult AIDS Clinical Trials Group study

Motsinger, A. A., Ritchie, M. D., Shafer, R. W., Robbins, G. K., Morse, G. D., Labbé, L., Wilkinson, G. R., Clifford, D. B., D'Aquila, R. T., Johnson, V. A., Pollard, R. B., Merigan, T. C., Hirsch, M. S., Donahue, J. P., Kim, R. B. & Haas, D. W., Nov 2006, In: Pharmacogenetics and Genomics. 16, 11, p. 837-845 9 p.

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Oxidant stress and peripheral neuropathy during antiretroviral therapy: An AIDS clinical trials group study

Hulgan, T., Hughes, M., Sun, X., Smeaton, L. M., Terry, E., Robbins, G. K., Shafer, R. W., Clifford, D. B., McComsey, G. A., Canter, J. A., Morrow, J. D. & Haas, D. W., Aug 2006, In: Journal of Acquired Immune Deficiency Syndromes. 42, 4, p. 450-454 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: An adult AIDS clinical trials group study

Ribaudo, H. J., Haas, D. W., Tierney, C., Kim, R. B., Wilkinson, G. R., Gulick, R. M., Clifford, D. B., Marzolini, C., Fletcher, C. V., Tashima, K. T., Kuritzkes, D. R. & Acosta, E. P., Feb 1 2006, In: Clinical Infectious Diseases. 42, 3, p. 401-407 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

194 Scopus citations

2007

A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment

Schifitto, G., Zhang, J., Evans, S. R., Sacktor, N., Simpson, D., Millar, L. L., Hung, V. L., Miller, E. N., Smith, E., Ellis, R. J., Valcour, V., Singer, E., Marra, C. M., Kolson, D., Weihe, J., Remmel, R., Katzenstein, D., Clifford, D. B., Nuffer, K. & Cahill, S. & 26 others, Burgess, D., Carter, K., Shoemaker, M., Weisbeck, A., Hanks, N., Watters, M., Chafey, S. A., Dunaway, S., Perrin, M., Quinn, J., Venna, N., Flynn, T., Spitz, T., Gould, M., Cohen, B., Reisberg, L., Diaz-Arrastia, R., Lohner, C., Marder, K., Clouse, R., Mildvan, D., Bailey, J., Tashima, K., Sousa, H., Currin, D. & Pedersen, S., Sep 2007, In: Neurology. 69, 13, p. 1314-1321 8 p.

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

A randomized trial evaluating Prosaptide™ for HIV-associated sensory neuropathies: Use of an electronic diary to record neuropathic pain

Evans, S. R., Simpson, D. M., Kitch, D. W., King, A., Clifford, D. B., Cohen, B. A. & McArthur, J. C., Jul 25 2007, In: PloS one. 2, 7, e551.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Correlates of epidermal nerve fiber densities in HIV-associated distal sensory polyneuropathy

Zhou, L., Kitch, D. W., Evans, S. R., Hauer, P., Raman, S., Ebenezer, G. J., Gerschenson, M., Marra, C. M., Valcour, V., Diaz-Arrastia, R., Goodkin, K., Millar, L., Shriver, S., Asmuth, D. M., Clifford, D. B., Simpson, D. M. & McArthur, J. C., Jun 2007, In: Neurology. 68, 24, p. 2113-2119 7 p.

Research output: Contribution to journal › Article › peer-review

95 Scopus citations

Erratum: Frequency and phenotype of JC virus-specific CD8⁺ T lymphocytes in the peripheral blood of patients with progressive multifocal leukoencephalopathy

Lima, M. A., Marzocchetti, A., Autissier, P., Tompkins, T., Chen, Y., Gordon, J., Clifford, D. B., Gandhi, R. T., Venna, N., Berger, J. R. & Koralnik, I. J., Oct 2007, In: Journal of virology. 81, 19, p. 10835 1 p.

Research output: Contribution to journal › Comment/debate

Factor in AIDS dementia complex trial design: Results and lessons from the abacavir trial

Brew, B. J., Halman, M., Catalan, J., Sacktor, N., Price, R. W., Brown, S., Atkinson, H., Clifford, D. B., Simpson, D., Torres, G., Hall, C., Power, C., Marder, K., McArthur, J. C., Symonds, W. & Romero, C., Mar 30 2007, In: PLoS Clinical Trials. 2, 3, e13.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Frequency and phenotype of JC virus-specific CD8⁺ T lymphocytes in the peripheral blood of patients with progressive multifocal leukoencephalopathy

Lima, M. A., Marzocchetti, A., Autissier, P., Tompkins, T., Chen, Y., Gordon, J., Clifford, D. B., Gandhi, R. T., Venna, N., Berger, J. R. & Koralnik, I. J., Apr 2007, In: Journal of virology. 81, 7, p. 3361-3368 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

Histoplasmoma: Isolated central nervous system infection with Histoplasma capsulatum in a patient with AIDS. Case report and brief review of the literature

Azizirad, O., Clifford, D. B., Groger, R. K., Prelutsky, D. & Schmidt, R. E., Feb 2007, In: Clinical Neurology and Neurosurgery. 109, 2, p. 176-181 6 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

HIV-associated cognitive impairment in sub-Saharan Africa - The potential effect of clade diversity

Sacktor, N., Nakasujja, N., Robertson, K. & Clifford, D. B., Aug 2007, In: Nature Clinical Practice Neurology. 3, 8, p. 436-443 8 p.

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

HIV-associated neuromuscular weakness syndrome in Brazil: Report of the two first cases

Vidal, J. E., Clifford, D., Ferreira, C. M. & Penalva De Oliveira, A. C., Sep 2007, In: Arquivos de Neuro-Psiquiatria. 65, 3 B, p. 848-851 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring

Kappos, L., Bates, D., Hartung, H. P., Havrdova, E., Miller, D., Polman, C. H., Ravnborg, M., Hauser, S. L., Rudick, R. A., Weiner, H. L., O'Connor, P. W., King, J., Radue, E. W., Yousry, T., Major, E. O. & Clifford, D. B., May 2007, In: Lancet Neurology. 6, 5, p. 431-441 11 p.

Research output: Contribution to journal › Review article › peer-review

178 Scopus citations

Neurological evaluation of untreated human immunodeficiency virus infected adults in Ethiopia

Clifford, D. B., Mitike, M. T., Mekonnen, Y., Zhang, J., Zenebe, G., Melaku, Z., Zewde, A., Gessesse, N., Wolday, D., Messele, T., Teshome, M. & Evans, S., Jan 2007, In: Journal of NeuroVirology. 13, 1, p. 67-72 6 p.

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Primary Neurological Manifestation of HIV/AIDS

Clifford, D. B. & Mitike, M. T., Jan 1 2007, Global HIV/AIDS Medicine. Elsevier, p. 261-269 9 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Selegiline Transdermal System (STS) for HIV-associated cognitive impairment: Open-label report of ACTG 5090

Evans, S. R., Yeh, T. M., Sacktor, N., Clifford, D. B., Simpson, D., Miller, E. N., Ellis, R. J., Valcour, V., Marra, C. M., Millar, L. & Schifitto, G., Nov 2007, In: HIV Clinical Trials. 8, 6, p. 437-446 10 p.

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

The role of cohort studies in drug development: Clinical evidence of antiviral activity of serotonin reuptake inhibitors and HMG-CoA reductase inhibitors in the central nervous system

Letendre, S. L., Marquie-Beck, J., Ellis, R. J., Woods, S. P., Best, B., Clifford, D. B., Collier, A. C., Gelman, B. B., Marra, C., McArthur, J. C., McCutchan, J. A., Morgello, S., Simpson, D., Alexander, T. J., Durelle, J., Heaton, R., Grant, I., Marcotte, T. D., Neumayer, S. & Capparelli, E. & 14 others, Atkinson, J. H., Franklin, D., Wong, J. K., Ignacio, C., Jernigan, T., Taylor, M. J., Theilmann, R., Gamst, A. C., Cushman, C., Frybarger, M., Abramson, I., Lazzaretto, D., Von Jaeger, R. & Al-Lozi, M., Mar 2007, In: Journal of Neuroimmune Pharmacology. 2, 1, p. 120-127 8 p.

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Updated research nosology for HIV-associated neurocognitive disorders

Antinori, A., Arendt, G., Becker, J. T., Brew, B. J., Byrd, D. A., Cherner, M., Clifford, D. B., Cinque, P., Epstein, L. G., Goodkin, K., Gisslen, M., Grant, I., Heaton, R. K., Joseph, J., Marder, K., Marra, C. M., McArthur, J. C., Nunn, M., Price, R. W. & Pulliam, L. & 4 others, Robertson, K. R., Sacktor, N., Valcour, V. & Wojna, V. E., Oct 2007, In: Neurology. 69, 18, p. 1789-1799 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2175 Scopus citations

2008

HIV-associated neurocognitive disease continues in the antiretroviral era.

Clifford, D. B., Jan 1 2008, In: Topics in HIV medicine : a publication of the International AIDS Society, USA. 16, 2, p. 94-98 5 p.

Research output: Contribution to journal › Article › peer-review

88 Scopus citations

HIV-associated neurocognitive disorders and the impact of combination antiretroviral therapies

Ances, B. M. & Clifford, D. B., Nov 2008, In: Current neurology and neuroscience reports. 8, 6, p. 455-461 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

Human immunodeficiency virus protease inhibitors and risk for peripheral neuropathy

Ellis, R. J., Marquie-Beck, J., Delaney, P., Alexander, T., Clifford, D. B., McArthur, J. C., Simpson, D. M., Ake, C., Collier, A. C., Gelman, B. B., McCutchan, J. A., Morgello, S., Grant, I., Marcotte, T. D., Franklin, D., Letendre, S., Capparelli, E., Durelle, J., Heaton, R. K. & Atkinson, J. H. & 23 others, Woods, S. P., Dawson, M., Wong, J. K., Jernigan, T., Taylor, M. J., Theilmann, R., Gamst, A. C., Cushman, C., Abramson, I., Vaida, F., Von Jaeger, R., McArthur, J., Mbeo, G., Simpson, D., Mintz, L., Ueland, S., Collier, A., Marra, C., Jones, T., Gelman, B., Heckendorn, E., Al-Lozi, M. & Teshome, M., Nov 1 2008, In: Annals of neurology. 64, 5, p. 566-572 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

77 Scopus citations

Natalizumab and PML: A risky business?

Clifford, D. B., Oct 2008, In: Gut. 57, 10, p. 1347-1349 3 p.

Research output: Contribution to journal › Comment/debate

14 Scopus citations

Second assessment of NeuroAIDS in Africa

Robertson, K., Kopnisky, K., Hakim, J., Merry, C., Nakasujja, N., Hall, C., Traore, M., Sacktor, N., Clifford, D., Newton, C., Van Rie, A., Holding, P., Clements, J., Zink, C., Mielke, J., Hosseinipour, M., Lalloo, U., Amod, F., Marra, C. & Evans, S. & 1 others, Liner, J., Mar 2008, In: Journal of NeuroVirology. 14, 2, p. 89-101 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

Simplification of the research diagnosis of HIV-associated sensory neuropathy

Evans, S. R., Clifford, D. B., Kitch, D. W., Goodkin, K., Schifitto, G., McArthur, J. C. & Simpson, D. M., Nov 2008, In: HIV Clinical Trials. 9, 6, p. 434-439 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy

Canter, J. A., Haas, D. W., Kallianpur, A. R., Ritchie, M. D., Robbins, G. K., Shafer, R. W., Clifford, D. B., Murdock, D. G. & Hulgan, T., Feb 2008, In: Pharmacogenomics Journal. 8, 1, p. 71-77 7 p.

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Validation of the CNS penetration-effectiveness rank for quantifying antiretroviral penetration into the central nervous system

Letendre, S., Marquie-Beck, J., Capparelli, E., Best, B., Clifford, D., Collier, A. C., Gelman, B. B., McArthur, J. C., McCutchan, J. A., Morgello, S., Simpson, D., Grant, I. & Ellis, R. J., Jan 2008, In: Archives of neurology. 65, 1, p. 65-70 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

706 Scopus citations

2009

Acetyl-L-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection

Valcour, V., Yeh, T. M., Bartt, R., Clifford, D., Gerschenson, M., Evans, S. R., Cohen, B. A., Ebenezer, G. J., Hauer, P., Millar, L., Gould, M., Tran, P., Shikuma, C., Souza, S. & Mcarthur, J. C., 2009, In: HIV Medicine. 10, 2, p. 103-110 8 p.

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Benefits and risks of stavudine therapy for HIV-associated neurologic complications in Uganda

Sacktor, N., Nakasujja, N., Skolasky, R. L., Robertson, K., Musisi, S., Ronald, A., Katabira, E. & Clifford, D. B., Jan 13 2009, In: Neurology. 72, 2, p. 165-170 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease

Clifford, D. B., Fagan, A. M., Holtzman, D. M., Morris, J. C., Teshome, M., Shah, A. R. & Kauwe, J. S. K., Dec 2009, In: Neurology. 73, 23, p. 1982-1987 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

144 Scopus citations

Determinants of survival in progressive multifocal leukoencephalopathy

Marzocchetti, A., Tompkins, T., Clifford, D. B., Gandhi, R. T., Kesari, S., Berger, J. R., Simpson, D. M., Prosperi, M., De Luca, A. & Koralnik, I. J., Nov 2009, In: Neurology. 73, 19, p. 1551-1558 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

151 Scopus citations

Effects of active HCV replication on neurologic status in HIV RNA virally suppressed patients

Clifford, D. B., Smurzynski, M., Park, L. S., Yeh, T. M., Zhao, Y., Blair, L., Arens, M. & Evans, S. R., Jul 2009, In: Neurology. 73, 4, p. 309-314 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

HIV subtype D is associated with dementia, compared with subtype A, in immunosuppressed individuals at risk of cognitive impairment in Kampala, Uganda

Sacktor, N., Nakasujja, N., Skolasky, R. L., Rezapour, M., Robertson, K., Musisi, S., Katabira, E., Ronald, A., Clifford, D. B., Laeyendecker, O. & Quinn, T. C., Sep 1 2009, In: Clinical Infectious Diseases. 49, 5, p. 780-786 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

110 Scopus citations

Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance

Marra, C. M., Zhao, Y., Clifford, D. B., Letendre, S., Evans, S., Henry, K., Ellis, R. J., Rodriguez, B., Coombs, R. W., Schifitto, G., McArthur, J. C. & Robertson, K., Jul 2009, In: AIDS. 23, 11, p. 1359-1366 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

301 Scopus citations

Long-term impact of efavirenz on neuropsychological performance and symptoms in HIV-infected individuals (ACTG 5097s)

Clifford, D. B., Evans, S., Yang, Y., Acosta, E. P., Ribaudo, H. & Gulick, R. M., Jan 1 2009, In: HIV Clinical Trials. 10, 6, p. 343-355 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

89 Scopus citations

Low atazanavir concentrations in cerebrospinal fluid

Best, B. M., Letendre, S. L., Brigid, E., Clifford, D. B., Collier, A. C., Gelman, B. B., McArthur, J. C., McCutchan, J. A., Simpson, D. M., Ellis, R., Capparelli, E. V. & Grant, I., Jan 2 2009, In: AIDS. 23, 1, p. 83-87 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

109 Scopus citations

Planning future strategies for domestic and international neuroAIDS research, july 24-25, 2008

Joseph, J., Clifford, D., Douglas, S. D., Fox, H., Gendelman, H. E., Gonzalez-Scarano, F., Grant, I., Major, E. & McArthur, J., Sep 2009, In: Journal of Neuroimmune Pharmacology. 4, 3, p. 283-297 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

David Clifford

Research output

Search results