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David Chen

Instructor in Medicine

    • 1319 Citations
    20022020

    Research output per year

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    Personal profile

    Research interests

    Cancer biology

    Areas of Clinical Interest

    Melanoma, skin cancer, mole mapping, atypical moles

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    Research Output

    • 1319 Citations
    • 12 Article
    • 2 Letter
    • 2 Review article

    Neutrophil-predominant bullous pemphigoid induced by checkpoint inhibitors: A case series

    Morris, L. M., Lewis, H. A., Cornelius, L. A., Chen, D. Y. & Rosman, I. S., Jan 1 2020, (Accepted/In press) In : Journal of cutaneous pathology.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

    Ketkar, S., Verdoni, A. M., Smith, A. M., Bangert, C. V., Leight, E. R., Chen, D. Y., Brune, M. K., Helton, N. M., Hoock, M., George, D. R., Fronick, C., Fulton, R. S., Ramakrishnan, S. M., Chang, G. S., Petti, A. A., Spencer, D. H., Miller, C. A. & Ley, T. J., Feb 11 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 6, p. 3123-3134 12 p.

    Research output: Contribution to journal › Article

    Open Access

    • A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing

    Petti, A. A., Williams, S. R., Miller, C. A., Fiddes, I. T., Srivatsan, S. N., Chen, D. Y., Fronick, C. C., Fulton, R. S., Church, D. M. & Ley, T. J., Dec 1 2019, In : Nature communications. 10, 1, 3660.

    Research output: Contribution to journal › Article

    Open Access
    • 16 Scopus citations

    DNMT3A R882 -associated hypomethylation patterns are maintained in primary AML xenografts, but not in the DNMT3A R882C OCI-AML3 leukemia cell line

    Chen, D., Christopher, M., Helton, N. M., Ferguson, I., Ley, T. J. & Spencer, D. H., Apr 1 2018, In : Blood cancer journal. 8, 4, 38.

    Research output: Contribution to journal › Letter

    Open Access
    4 Scopus citations

    A metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas

    Bean, G. R., Kremer, J. C., Prudner, B. C., Schenone, A. D., Yao, J. C., Schultze, M. B., Chen, D. Y., Tanas, M. R., Adkins, D. R., Bomalaski, J., Rubin, B. P., Michel, L. S. & Van Tine, B. A., Jan 1 2016, In : Cell Death and Disease. 7, 10, e2406.

    Research output: Contribution to journal › Article

    Open Access
    • 30 Scopus citations