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Daved Fremont

Professor of Pathology and Immunology, Professor of Biochemistry and Molecular Biophysics, Professor of Molecular Microbiology

 https://orcid.org/0000-0002-8544-2689
    • 12928 Citations
    1989 …2020

    Research output per year

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    Personal profile

    Research interests

    My research group is focused on understanding surveillance processes of the immune system, and the sabotage mechanisms used by viruses to evade detection and host-mediated elimination.

    Keywords

    • COVID-19

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    Research Output

    Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans

    Ellebedy, A. H., Nachbagauer, R., Jackson, K. J. L., Dai, Y. N., Han, J., Alsoussi, W. B., Davis, C. W., Stadlbauer, D., Rouphael, N., Chromikova, V., McCausland, M., Chang, C. Y., Cortese, M., Bower, M., Chennareddy, C., Schmitz, A. J., Zarnitsyna, V. I., Lai, L., Rajabhathor, A., Kazemian, C. & 8 others, Antia, R., Mulligan, M. J., Ward, A. B., Fremont, D. H., Boyd, S. D., Pulendran, B., Krammer, F. & Ahmed, R., Jul 28 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 30, p. 17957-17964 8 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis

    Kim, A. S., Zimmerman, O., Fox, J. M., Nelson, C. A., Basore, K., Zhang, R., Durnell, L., Desai, C., Bullock, C., Deem, S. L., Oppenheimer, J., Shapiro, B., Wang, T., Cherry, S., Coyne, C. B., Handley, S. A., Landis, M. J., Fremont, D. H. & Diamond, M. S., Mar 11 2020, In : Cell Host and Microbe. 27, 3, p. 428-440.e9

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    A potently neutralizing antibody protects mice against SARS-CoV-2 infection

    Alsoussi, W. B., Turner, J. S., Case, J. B., Zhao, H., Schmitz, A. J., Zhou, J. Q., Chen, R. E., Lei, T., Rizk, A. A., McIntire, K. M., Winkler, E. S., Fox, J. M., Kafai, N. M., Thackray, L. B., Hassan, A. O., Amanat, F., Krammer, F., Watson, C. T., Kleinstein, S. H., Fremont, D. H. & 2 others, Diamond, M. S. & Ellebedy, A. H., Aug 15 2020, In : Journal of Immunology. 205, 4, p. 915-922 8 p.

    Research output: Contribution to journal › Article

    Open Access
    • 5 Scopus citations

    A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

    Hassan, A. O., Case, J. B., Winkler, E. S., Thackray, L., Kafai, N. M., Bailey, A. L., McCune, B. T., Fox, J. M., Chen, R. E., Alsoussi, W. B., Turner, J. S., Schmitz, A. J., Lei, T., Shrihari, S., Keeler, S. P., Fremont, D., Greco, S., McCray, P. B., Perlman, S., Holtzman, M. J. & 2 others, Ellebedy, A. & Diamond, M. S., Jan 1 2020, (Accepted/In press) In : Cell.

    Research output: Contribution to journal › Article

    Open Access
    • 29 Scopus citations

    A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

    Hassan, A. O., Kafai, N. M., Dmitriev, I. P., Fox, J. M., Smith, B. K., Harvey, I. B., Chen, R. E., Winkler, E. S., Wessel, A. W., Case, J. B., Kashentseva, E., McCune, B. T., Bailey, A. L., Zhao, H., VanBlargan, L. A., Dai, Y. N., Ma, M., Adams, L. J., Shrihari, S., Danis, J. E. & 11 others, Gralinski, L. E., Hou, Y. J., Schäfer, A., Kim, A. S., Keeler, S. P., Weiskopf, D., Baric, R. S., Holtzman, M. J., Fremont, D. H., Curiel, D. T. & Diamond, M. S., Oct 1 2020, In : Cell. 183, 1, p. 169-184.e13

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations