Dave Pagliarini

2023

Nitric oxide-driven modifications of lipoic arm inhibit α-ketoacid dehydrogenases

Seim, G. L., John, S. V., Arp, N. L., Fang, Z., Pagliarini, D. J. & Fan, J., Mar 2023, In: Nature Chemical Biology. 19, 3, p. 265-274 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Small-molecule inhibition of the archetypal UbiB protein COQ8

Murray, N. H., Asquith, C. R. M., Fang, Z., East, M. P., Ptak, N., Smith, R. W., Vasta, J. D., Zimprich, C. A., Corona, C. R., Robers, M. B., Johnson, G. L., Bingman, C. A. & Pagliarini, D. J., Feb 2023, In: Nature Chemical Biology. 19, 2, p. 230-238 9 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2022

2-Propylphenol Allosterically Modulates COQ8A to Enhance ATPase Activity

Murray, N. H., Lewis, A., Rincon Pabon, J. P., Gross, M. L., Henzler-Wildman, K. & Pagliarini, D. J., Aug 19 2022, In: ACS Chemical Biology. 17, 8, p. 2031-2038 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Defining mitochondrial protein functions through deep multiomic profiling

Rensvold, J. W., Shishkova, E., Sverchkov, Y., Miller, I. J., Cetinkaya, A., Pyle, A., Manicki, M., Brademan, D. R., Alanay, Y., Raiman, J., Jochem, A., Hutchins, P. D., Peters, S. R., Linke, V., Overmyer, K. A., Salome, A. Z., Hebert, A. S., Vincent, C. E., Kwiecien, N. W., Rush, M. J. P., & 6 othersWestphall, M. S., Craven, M., Akarsu, N. A., Taylor, R. W., Coon, J. J. & Pagliarini, D. J., Jun 9 2022, In: Nature. 606, 7913, p. 382-388 7 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Structure and functionality of a multimeric human COQ7:COQ9 complex

Manicki, M., Aydin, H., Abriata, L. A., Overmyer, K. A., Guerra, R. M., Coon, J. J., Dal Peraro, M., Frost, A. & Pagliarini, D. J., Nov 17 2022, In: Molecular cell. 82, 22, p. 4307-4323.e10

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2021

Classification of T-cell activation via autofluorescence lifetime imaging

Walsh, A. J., Mueller, K. P., Tweed, K., Jones, I., Walsh, C. M., Piscopo, N. J., Niemi, N. M., Pagliarini, D. J., Saha, K. & Skala, M. C., Jan 2021, In: Nature Biomedical Engineering. 5, 1, p. 77-88 12 p.

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Defining intermediates and redundancies in coenzyme Q precursor biosynthesis

Robinson, K. P., Jochem, A., Johnson, S. E., Reddy, T. R., Russell, J. D., Coon, J. J. & Pagliarini, D. J., Apr 14 2021, In: Journal of Biological Chemistry. 296, 100643.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen-storage-associated mitochondriopathy

Wong, H. H., Seet, S. H., Maier, M., Gurel, A., Traspas, R. M., Lee, C., Zhang, S., Talim, B., Loh, A. Y. T., Chia, C. Y., Teoh, T. S., Sng, D., Rensvold, J., Unal, S., Shishkova, E., Cepni, E., Nathan, F. M., Sirota, F. L., Liang, C., Yarali, N., & 52 othersSimsek-Kiper, P. O., Mitani, T., Ceylaner, S., Arman-Bilir, O., Mbarek, H., Gumruk, F., Efthymiou, S., Uğurlu Çi̇men, D., Georgiadou, D., Sotiropoulou, K., Houlden, H., Paul, F., Pehlivan, D., Lainé, C., Chai, G., Ali, N. A., Choo, S. C., Keng, S. S., Boisson, B., Yılmaz, E., Xue, S., Coon, J. J., Ly, T. T. N., Gilani, N., Hasbini, D., Kayserili, H., Zaki, M. S., Isfort, R. J., Ordonez, N., Tripolszki, K., Bauer, P., Rezaei, N., Seyedpour, S., Khotaei, G. T., Bascom, C. C., Maroofian, R., Chaabouni, M., Alsubhi, A., Eyaid, W., Işıkay, S., Gleeson, J. G., Lupski, J. R., Casanova, J. L., Pagliarini, D. J., Akarsu, N. A., Maurer-Stroh, S., Cetinkaya, A., Bertoli-Avella, A., Mathuru, A. S., Ho, L., Bard, F. A. & Reversade, B., Jul 1 2021, In: American journal of human genetics. 108, 7, p. 1301-1317 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Multi-Omic Single-Shot Technology for Integrated Proteome and Lipidome Analysis

He, Y., Rashan, E. H., Linke, V., Shishkova, E., Hebert, A. S., Jochem, A., Westphall, M. S., Pagliarini, D. J., Overmyer, K. A. & Coon, J. J., Mar 9 2021, In: Analytical Chemistry. 93, 9, p. 4217-4222 6 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function

Rosier, K., McDevitt, M. T., Smet, J., Floyd, B. J., Verschoore, M., Marcaida, M. J., Bingman, C. A., Lemmens, I., Dal Peraro, M., Tavernier, J., Cravatt, B. F., Gounko, N. V., Vints, K., Monnens, Y., Bhalla, K., Aerts, L., Rashan, E. H., Vanlander, A. V., Van Coster, R., Régal, L., & 2 othersPagliarini, D. J. & Creemers, J. W. M., Dec 17 2021, In: iScience. 24, 12, 103460.

Research output: Contribution to journal › Article › peer-review

Open Access

The extensive and functionally uncharacterized mitochondrial phosphoproteome

Niemi, N. M. & Pagliarini, D. J., Jul 1 2021, In: Journal of Biological Chemistry. 297, 1, 100880.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2020

Argonaut: A Web Platform for Collaborative Multi-omic Data Visualization and Exploration

Brademan, D. R., Miller, I. J., Kwiecien, N. W., Pagliarini, D. J., Westphall, M. S., Coon, J. J. & Shishkova, E., Oct 9 2020, In: Patterns. 1, 7, 100122.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Clinico-Genetic, Imaging and Molecular Delineation of COQ8A-Ataxia: A Multicenter Study of 59 Patients

Traschütz, A., Schirinzi, T., Laugwitz, L., Murray, N. H., Bingman, C. A., Reich, S., Kern, J., Heinzmann, A., Vasco, G., Bertini, E., Zanni, G., Durr, A., Magri, S., Taroni, F., Malandrini, A., Baets, J., de Jonghe, P., de Ridder, W., Bereau, M., Demuth, S., & 22 othersGanos, C., Basak, A. N., Hanagasi, H., Kurul, S. H., Bender, B., Schöls, L., Grasshoff, U., Klopstock, T., Horvath, R., van de Warrenburg, B., Burglen, L., Rougeot, C., Ewenczyk, C., Koenig, M., Santorelli, F. M., Anheim, M., Munhoz, R. P., Haack, T., Distelmaier, F., Pagliarini, D. J., Puccio, H. & Synofzik, M., Aug 1 2020, In: Annals of neurology. 88, 2, p. 251-263 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy

Stefely, J. A., Zhang, Y., Freiberger, E. C., Kwiecien, N. W., Thomas, H. E., Davis, A. M., Lowry, N. D., Vincent, C. E., Shishkova, E., Clark, N. A., Medvedovic, M., Coon, J. J., Pagliarini, D. J. & Mercer, C. A., 2020, In: Autophagy. 16, 12, p. 2219-2237 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Pathogenic Bi-allelic Mutations in NDUFAF8 Cause Leigh Syndrome with an Isolated Complex I Deficiency

Alston, C. L., Veling, M. T., Heidler, J., Taylor, L. S., Alaimo, J. T., Sung, A. Y., He, L., Hopton, S., Broomfield, A., Pavaine, J., Diaz, J., Leon, E., Wolf, P., McFarland, R., Prokisch, H., Wortmann, S. B., Bonnen, P. E., Wittig, I., Pagliarini, D. J. & Taylor, R. W., Jan 2 2020, In: American journal of human genetics. 106, 1, p. 92-101 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Quantitative shotgun proteome analysis by direct infusion

Meyer, J. G., Niemi, N. M., Pagliarini, D. J. & Coon, J. J., Dec 2020, In: Nature Methods. 17, 12, p. 1222-1228 7 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

2019

An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis

Lohman, D. C., Aydin, D., Von Bank, H. C., Smith, R. W., Linke, V., Weisenhorn, E., McDevitt, M. T., Hutchins, P., Wilkerson, E. M., Wancewicz, B., Russell, J., Stefely, M. S., Beebe, E. T., Jochem, A., Coon, J. J., Bingman, C. A., Dal Peraro, M. & Pagliarini, D. J., Feb 21 2019, In: Molecular cell. 73, 4, p. 763-774.e10

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER-mitochondria contacts

Subramanian, K., Jochem, A., Vasseur, M. L., Lewis, S., Paulson, B. R., Reddy, T. R., Russell, J. D., Coon, J. J., Pagliarini, D. J. & Nunnari, J., 2019, In: Journal of Cell Biology. 218, 4, p. 1352-1368 17 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at complex I in pancreatic -cells

Gregg, T., Sdao, S. M., Dhillon, R. S., Rensvold, J. W., Lewandowski, S. L., Pagliarini, D. J., Denu, J. M. & Merrins, M. J., Mar 22 2019, In: Journal of Biological Chemistry. 294, 12, p. 4656-4666 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis

Niemi, N. M., Wilson, G. M., Overmyer, K. A., Vögtle, F. N., Myketin, L., Lohman, D. C., Schueler, K. L., Attie, A. D., Meisinger, C., Coon, J. J. & Pagliarini, D. J., Dec 1 2019, In: Nature communications. 10, 1, 3197.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation

Seim, G. L., Britt, E. C., John, S. V., Yeo, F. J., Johnson, A. R., Eisenstein, R. S., Pagliarini, D. J. & Fan, J., Jul 1 2019, In: Nature Metabolism. 1, 7, p. 731-742 12 p.

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

2018

A path to the powerhouse: systems-to-structure approaches for studying mitochondrial proteins

Pagliarini, D. J., Aug 2018, In: Protein Science. 27, 8, p. 1518-1525 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family

Reidenbach, A. G., Kemmerer, Z. A., Aydin, D., Jochem, A., McDevitt, M. T., Hutchins, P. D., Stark, J. L., Stefely, J. A., Reddy, T., Hebert, A. S., Wilkerson, E. M., Johnson, I. E., Bingman, C. A., Markley, J. L., Coon, J. J., Dal Peraro, M. & Pagliarini, D. J., Feb 15 2018, In: Cell Chemical Biology. 25, 2, p. 154-165.e11

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

DNA Polymerase θ Increases Mutational Rates in Mitochondrial DNA

Wisnovsky, S., Sack, T., Pagliarini, D. J., Laposa, R. R. & Kelley, S. O., Apr 20 2018, In: ACS Chemical Biology. 13, 4, p. 900-908 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes

Jha, P., McDevitt, M. T., Halilbasic, E., Williams, E. G., Quiros, P. M., Gariani, K., Sleiman, M. B., Gupta, R., Ulbrich, A., Jochem, A., Coon, J. J., Trauner, M., Pagliarini, D. J. & Auwerx, J., Jun 27 2018, In: Cell Systems. 6, 6, p. 709-721.e6

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Identification and Quantification of Murine Mitochondrial Proteoforms Using an Integrated Top-Down and Intact-Mass Strategy

Schaffer, L. V., Rensvold, J. W., Shortreed, M. R., Cesnik, A. J., Jochem, A., Scalf, M., Frey, B. L., Pagliarini, D. J. & Smith, L. M., Oct 5 2018, In: Journal of Proteome Research. 17, 10, p. 3526-3536 11 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Multi-omics Reveal Specific Targets of the RNA-Binding Protein Puf3p and Its Orchestration of Mitochondrial Biogenesis

Lapointe, C. P., Stefely, J. A., Jochem, A., Hutchins, P. D., Wilson, G. M., Kwiecien, N. W., Coon, J. J., Wickens, M. & Pagliarini, D. J., Jan 24 2018, In: Cell Systems. 6, 1, p. 125-135.e6

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species

Jha, P., McDevitt, M. T., Gupta, R., Quiros, P. M., Williams, E. G., Gariani, K., Sleiman, M. B., Diserens, L., Jochem, A., Ulbrich, A., Coon, J. J., Auwerx, J. & Pagliarini, D. J., Jun 27 2018, In: Cell Systems. 6, 6, p. 722-733.e6

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

2017

Erythropoietin signaling regulates heme biosynthesis

Chung, J., Wittig, J. G., Ghamari, A., Maeda, M., Dailey, T. A., Bergonia, H., Kafina, M. D., Coughlin, E. E., Minogue, C. E., Hebert, A. S., Li, L., Kaplan, J., Lodish, H. F., Bauer, D. E., Orkin, S. H., Cantor, A. B., Maeda, T., Phillips, J. D., Coon, J. J., Pagliarini, D. J., & 2 othersDailey, H. A. & Paw, B. H., May 29 2017, In: eLife. 6, e24767.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase

Guo, X., Niemi, N. M., Coon, J. J. & Pagliarini, D. J., Jul 14 2017, In: Journal of Biological Chemistry. 292, 28, p. 11751-11759 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Multi-omic Mitoprotease Profiling Defines a Role for Oct1p in Coenzyme Q Production

Veling, M. T., Reidenbach, A. G., Freiberger, E. C., Kwiecien, N. W., Hutchins, P. D., Drahnak, M. J., Jochem, A., Ulbrich, A., Rush, M. J. P., Russell, J. D., Coon, J. J. & Pagliarini, D. J., Dec 7 2017, In: Molecular cell. 68, 5, p. 970-977.e11

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Ptc7p Dephosphorylates Select Mitochondrial Proteins to Enhance Metabolic Function

Guo, X., Niemi, N. M., Hutchins, P. D., Condon, S. G. F., Jochem, A., Ulbrich, A., Higbee, A. J., Russell, J. D., Senes, A., Coon, J. J. & Pagliarini, D. J., Jan 10 2017, In: Cell Reports. 18, 2, p. 307-313 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

2016

Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity

Stefely, J. A., Licitra, F., Laredj, L., Reidenbach, A. G., Kemmerer, Z. A., Grangeray, A., Jaeg-Ehret, T., Minogue, C. E., Ulbrich, A., Hutchins, P. D., Wilkerson, E. M., Ruan, Z., Aydin, D., Hebert, A. S., Guo, X., Freiberger, E. C., Reutenauer, L., Jochem, A., Chergova, M., Johnson, I. E., & 18 othersLohman, D. C., Rush, M. J. P., Kwiecien, N. W., Singh, P. K., Schlagowski, A. I., Floyd, B. J., Forsman, U., Sindelar, P. J., Westphall, M. S., Pierrel, F., Zoll, J., Dal Peraro, M., Kannan, N., Bingman, C. A., Coon, J. J., Isope, P., Puccio, H. & Pagliarini, D. J., Aug 18 2016, In: Molecular cell. 63, 4, p. 608-620 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

74 Scopus citations

Iron deprivation induces transcriptional regulation of mitochondrial biogenesis

Rensvold, J. W., Krautkramer, K. A., Dowell, J. A., Denu, J. M. & Pagliarini, D. J., Sep 30 2016, In: Journal of Biological Chemistry. 291, 40, p. 20827-20837 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling

Stefely, J. A., Kwiecien, N. W., Freiberger, E. C., Richards, A. L., Jochem, A., Rush, M. J. P., Ulbrich, A., Robinson, K. P., Hutchins, P. D., Veling, M. T., Guo, X., Kemmerer, Z. A., Connors, K. J., Trujillo, E. A., Sokol, J., Marx, H., Westphall, M. S., Hebert, A. S., Pagliarini, D. J. & Coon, J. J., Nov 1 2016, In: Nature Biotechnology. 34, 11, p. 1191-1197 7 p.

Research output: Contribution to journal › Article › peer-review

102 Scopus citations

Mitochondrial protein hyperacetylation in the failing heart

Horton, J. L., Martin, O. J., Lai, L., Riley, N. M., Richards, A. L., Vega, R. B., Leone, T. C., Pagliarini, D. J., Muoio, D. M., Bedi, K. C., Margulies, K. B., Coon, J. J. & Kelly, D. P., Feb 25 2016, In: JCI Insight. 1, 2, e84897.

Research output: Contribution to journal › Article › peer-review

Open Access

131 Scopus citations

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function

Floyd, B. J., Wilkerson, E. M., Veling, M. T., Minogue, C. E., Xia, C., Beebe, E. T., Wrobel, R. L., Cho, H., Kremer, L. S., Alston, C. L., Gromek, K. A., Dolan, B. K., Ulbrich, A., Stefely, J. A., Bohl, S. L., Werner, K. M., Jochem, A., Westphall, M. S., Rensvold, J. W., Taylor, R. W., & 4 othersProkisch, H., Kim, J. J. P., Coon, J. J. & Pagliarini, D. J., Aug 18 2016, In: Molecular cell. 63, 4, p. 621-632 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

175 Scopus citations

2015

A Single Kinase Generates the Majority of the Secreted Phosphoproteome

Tagliabracci, V. S., Wiley, S. E., Guo, X., Kinch, L. N., Durrant, E., Wen, J., Xiao, J., Cui, J., Nguyen, K. B., Engel, J. L., Coon, J. J., Grishin, N., Pinna, L. A., Pagliarini, D. J. & Dixon, J. E., Jun 20 2015, In: Cell. 161, 7, p. 1619-1632 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

203 Scopus citations

Maximal oxidative capacity during exercise is associated with skeletal muscle fuel selection and dynamic changes in mitochondrial protein acetylation

Overmyer, K. A., Evans, C. R., Qi, N. R., Minogue, C. E., Carson, J. J., Chermside-Scabbo, C. J., Koch, L. G., Britton, S. L., Pagliarini, D. J., Coon, J. J. & Burant, C. F., Mar 3 2015, In: Cell metabolism. 21, 3, p. 468-478 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

98 Scopus citations

Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q Biosynthesis

Stefely, J. A., Reidenbach, A. G., Ulbrich, A., Oruganty, K., Floyd, B. J., Jochem, A., Saunders, J. M., Johnson, I. E., Minogue, C. E., Wrobel, R. L., Barber, G. E., Lee, D., Li, S., Kannan, N., Coon, J. J., Bingman, C. A. & Pagliarini, D. J., Jan 8 2015, In: Molecular cell. 57, 1, p. 83-94 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

78 Scopus citations

Multiplexed Quantification for Data-Independent Acquisition

Minogue, C. E., Hebert, A. S., Rensvold, J. W., Westphall, M. S., Pagliarini, D. J. & Coon, J. J., Mar 3 2015, In: Analytical Chemistry. 87, 5, p. 2570-2575 6 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

2014

A gly-zipper motif mediates homodimerization of the transmembrane domain of the mitochondrial kinase ADCK3

Khadria, A. S., Mueller, B. K., Stefely, J. A., Tan, C. H., Pagliarini, D. J. & Senes, A., Oct 8 2014, In: Journal of the American Chemical Society. 136, 40, p. 14068-14077 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Intelligent data acquisition blends targeted and discovery methods

Bailey, D. J., McDevitt, M. T., Westphall, M. S., Pagliarini, D. J. & Coon, J. J., Apr 4 2014, In: Journal of Proteome Research. 13, 4, p. 2152-2161 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis

Lohman, D. C., Forouhar, F., Beebe, E. T., Stefely, M. S., Minogue, C. E., Ulbrich, A., Stefely, J. A., Sukumar, S., Luna-Sánchez, M., Jochem, A., Lew, S., Seetharaman, J., Xiao, R., Wang, H., Westphall, M. S., Wrobel, R. L., Everett, J. K., Mitchell, J. C., Ló Pez, L. C., Coon, J. J., & 2 othersTong, L. & Pagliarini, D. J., Nov 4 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 44, p. 4697-4705 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

84 Scopus citations

Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in caenorhabditis elegans

Dingley, S. D., Polyak, E., Ostrovsky, J., Srinivasan, S., Lee, I., Rosenfeld, A. B., Tsukikawa, M., Xiao, R., Selak, M. A., Coon, J. J., Hebert, A. S., Grimsrud, P. A., Kwon, Y. J., Pagliarini, D. J., Gai, X., Schurr, T. G., Hüttemann, M., Nakamaru-Ogiso, E. & Falk, M. J., May 29 2014, In: Journal of Molecular Biology. 426, 11, p. 2199-2216 18 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Neutron-encoded mass signatures for quantitative top-down proteomics

Rhoads, T. W., Rose, C. M., Bailey, D. J., Riley, N. M., Molden, R. C., Nestler, A. J., Merrill, A. E., Smith, L. M., Hebert, A. S., Westphall, M. S., Pagliarini, D. J., Garcia, B. A. & Coon, J. J., Mar 4 2014, In: Analytical Chemistry. 86, 5, p. 2314-2319 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

2013

Amine-reactive neutron-encoded labels for highly plexed proteomic quantitation

Hebert, A. S., Merrill, A. E., Stefely, J. A., Bailey, D. J., Wenger, C. D., Westphall, M. S., Pagliarini, D. J. & Coon, J. J., Nov 2013, In: Molecular and Cellular Proteomics. 12, 11, p. 3360-3369 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

Automated gas-phase purification for accurate, multiplexed quantification on a stand-alone ion-trap mass spectrometer

Vincent, C. E., Rensvold, J. W., Westphall, M. S., Pagliarini, D. J. & Coon, J. J., Feb 19 2013, In: Analytical Chemistry. 85, 4, p. 2079-2086 8 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

Hebert, A. S., Dittenhafer-Reed, K. E., Yu, W., Bailey, D. J., Selen, E. S., Boersma, M. D., Carson, J. J., Tonelli, M., Balloon, A. J., Higbee, A. J., Westphall, M. S., Pagliarini, D. J., Prolla, T. A., Assadi-Porter, F., Roy, S., Denu, J. M. & Coon, J. J., Jan 10 2013, In: Molecular cell. 49, 1, p. 186-199 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

406 Scopus citations

Complementary RNA and Protein Profiling Identifies Iron as a Key Regulator of Mitochondrial Biogenesis

Rensvold, J. W., Ong, S. E., Jeevananthan, A., Carr, S. A., Mootha, V. K. & Pagliarini, D. J., Jan 31 2013, In: Cell Reports. 3, 1, p. 237-245 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Dave Pagliarini

Research output

Search results