Dave Pagliarini

2025

DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis

Ismail, V. A., Schuetz, M., Baker, Z. N., Castillo-Badillo, J. A., Naismith, T. V., Pagliarini, D. J. & Kast, D. J., Jan 2025, In: Journal of lipid research. 66, 1, 100700.

Research output: Contribution to journal › Article › peer-review

Open Access

Identification of a new COQ4 spliceogenic variant causing severe primary coenzyme Q deficiency

Alcázar-Fabra, M., Østergaard, E., Fernández-Ayala, D. J. M., Desbats, M. A., Morbidoni, V., Tomás-Gallado, L., García-Corzo, L., Blanquer-Roselló, M. D. M., Bartlett, A. K., Sánchez-Cuesta, A., Sena, L., Cortés-Rodríguez, A., Cascajo-Almenara, M. V., Pagliarini, D. J., Trevisson, E., Gronborg, S. W. & Brea-Calvo, G., Mar 2025, In: Molecular Genetics and Metabolism Reports. 42, 101176.

Research output: Contribution to journal › Article › peer-review

Open Access

Triacylglycerol mobilization underpins mitochondrial stress recovery

Baker, Z. N., Zhu, Y., Guerra, R. M., Smith, A. J., Arra, A., Serrano, L. R., Overmyer, K. A., Mukherji, S., Craig, E. A., Coon, J. J. & Pagliarini, D. J., Feb 2025, In: Nature Cell Biology. 27, 2, p. 298-308 11 p., 4363.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Coenzyme Q₄ is a functional substitute for coenzyme Q₁₀ and can be targeted to the mitochondria

Steenberge, L. H., Rogers, S., Sung, A. Y., Fan, J. & Pagliarini, D. J., May 2024, In: Journal of Biological Chemistry. 300, 5, 107269.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

COQ4 is required for the oxidative decarboxylation of the C1 carbon of coenzyme Q in eukaryotic cells

Pelosi, L., Morbiato, L., Burgardt, A., Tonello, F., Bartlett, A. K., Guerra, R. M., Ferizhendi, K. K., Desbats, M. A., Rascalou, B., Marchi, M., Vázquez-Fonseca, L., Agosto, C., Zanotti, G., Roger-Margueritat, M., Alcázar-Fabra, M., García-Corzo, L., Sánchez-Cuesta, A., Navas, P., Brea-Calvo, G. & Trevisson, E. & 4 others, Wendisch, V. F., Pagliarini, D. J., Salviati, L. & Pierrel, F., Mar 7 2024, In: Molecular cell. 84, 5, p. 981-989.e7

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Fast and deep phosphoproteome analysis with the Orbitrap Astral mass spectrometer

Lancaster, N. M., Sinitcyn, P., Forny, P., Peters-Clarke, T. M., Fecher, C., Smith, A. J., Shishkova, E., Arrey, T. N., Pashkova, A., Robinson, M. L., Arp, N., Fan, J., Hansen, J., Galmozzi, A., Serrano, L. R., Rojas, J., Gasch, A. P., Westphall, M. S., Stewart, H. & Hock, C. & 4 others, Damoc, E., Pagliarini, D. J., Zabrouskov, V. & Coon, J. J., Dec 2024, In: Nature communications. 15, 1, 7016.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Missense variants in CMS22 patients reveal that PREPL has both enzymatic and nonenzymatic functions

Monnens, Y., Theodoropoulou, A., Rosier, K., Bhalla, K., Mahy, A., Vanhoutte, R., Meulemans, S., Cavani, E., Antanasijevic, A., Lemmens, I., Lee, J. A., Spellicy, C. J., Schroer, R. J., Maselli, R. A., Laverty, C. G., Agostinis, P., Pagliarini, D. J., Verhelst, S., Marcaida, M. J. & Rochtus, A. & 2 others, Peraro, M. D. & Creemers, J. W. M., Sep 10 2024, In: JCI Insight. 9, 17, e179276.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Mitochondrial proteome research: the road ahead

Baker, Z. N., Forny, P. & Pagliarini, D. J., Jan 2024, In: Nature Reviews Molecular Cell Biology. 25, 1, p. 65-82 18 p.

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Reducing mitochondrial mysteries

Guerra, R. M. & Pagliarini, D. J., Feb 2024, In: Nature Chemical Biology. 20, 2, p. 132-133 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

Systematic analysis of NDUFAF6 in complex I assembly and mitochondrial disease

Sung, A. Y., Guerra, R. M., Steenberge, L. H., Alston, C. L., Murayama, K., Okazaki, Y., Shimura, M., Prokisch, H., Ghezzi, D., Torraco, A., Carrozzo, R., Rötig, A., Taylor, R. W., Keck, J. L. & Pagliarini, D. J., Jun 2024, In: Nature Metabolism. 6, 6, p. 1128-1142 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2023

Aim18p and Aim46p are chalcone isomerase domain–containing mitochondrial hemoproteins in Saccharomyces cerevisiae

Schmitz, J. M., Wolters, J. F., Murray, N. H., Guerra, R. M., Bingman, C. A., Hittinger, C. T. & Pagliarini, D. J., Mar 2023, In: Journal of Biological Chemistry. 299, 3, 102981.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Coenzyme Q biochemistry and biosynthesis

Guerra, R. M. & Pagliarini, D. J., May 2023, In: Trends in biochemical sciences. 48, 5, p. 463-476 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

50 Scopus citations

Hem25p is required for mitochondrial IPP transport in fungi

Tai, J., Guerra, R. M., Rogers, S. W., Fang, Z., Muehlbauer, L. K., Shishkova, E., Overmyer, K. A., Coon, J. J. & Pagliarini, D. J., Nov 2023, In: Nature Cell Biology. 25, 11, p. 1616-1624 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Nitric oxide-driven modifications of lipoic arm inhibit α-ketoacid dehydrogenases

Seim, G. L., John, S. V., Arp, N. L., Fang, Z., Pagliarini, D. J. & Fan, J., Mar 2023, In: Nature Chemical Biology. 19, 3, p. 265-274 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

PPTC7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy

Niemi, N. M., Serrano, L. R., Muehlbauer, L. K., Balnis, C. E., Wei, L., Smith, A. J., Kozul, K. L., Forny, M., Connor, O. M., Rashan, E. H., Shishkova, E., Schueler, K. L., Keller, M. P., Attie, A. D., Friedman, J. R., Pagan, J. K., Coon, J. J. & Pagliarini, D. J., Dec 2023, In: Nature communications. 14, 1, 6431.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Small-molecule inhibition of the archetypal UbiB protein COQ8

Murray, N. H., Asquith, C. R. M., Fang, Z., East, M. P., Ptak, N., Smith, R. W., Vasta, J. D., Zimprich, C. A., Corona, C. R., Robers, M. B., Johnson, G. L., Bingman, C. A. & Pagliarini, D. J., Feb 2023, In: Nature Chemical Biology. 19, 2, p. 230-238 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2022

2-Propylphenol Allosterically Modulates COQ8A to Enhance ATPase Activity

Murray, N. H., Lewis, A., Rincon Pabon, J. P., Gross, M. L., Henzler-Wildman, K. & Pagliarini, D. J., Aug 19 2022, In: ACS Chemical Biology. 17, 8, p. 2031-2038 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Defining mitochondrial protein functions through deep multiomic profiling

Rensvold, J. W., Shishkova, E., Sverchkov, Y., Miller, I. J., Cetinkaya, A., Pyle, A., Manicki, M., Brademan, D. R., Alanay, Y., Raiman, J., Jochem, A., Hutchins, P. D., Peters, S. R., Linke, V., Overmyer, K. A., Salome, A. Z., Hebert, A. S., Vincent, C. E., Kwiecien, N. W. & Rush, M. J. P. & 6 others, Westphall, M. S., Craven, M., Akarsu, N. A., Taylor, R. W., Coon, J. J. & Pagliarini, D. J., Jun 9 2022, In: Nature. 606, 7913, p. 382-388 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

Structure and functionality of a multimeric human COQ7:COQ9 complex

Manicki, M., Aydin, H., Abriata, L. A., Overmyer, K. A., Guerra, R. M., Coon, J. J., Dal Peraro, M., Frost, A. & Pagliarini, D. J., Nov 17 2022, In: Molecular cell. 82, 22, p. 4307-4323.e10

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2021

Classification of T-cell activation via autofluorescence lifetime imaging

Walsh, A. J., Mueller, K. P., Tweed, K., Jones, I., Walsh, C. M., Piscopo, N. J., Niemi, N. M., Pagliarini, D. J., Saha, K. & Skala, M. C., Jan 2021, In: Nature Biomedical Engineering. 5, 1, p. 77-88 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

109 Scopus citations

Defining intermediates and redundancies in coenzyme Q precursor biosynthesis

Robinson, K. P., Jochem, A., Johnson, S. E., Reddy, T. R., Russell, J. D., Coon, J. J. & Pagliarini, D. J., Apr 14 2021, In: Journal of Biological Chemistry. 296, 100643.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Erratum: Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen-storage-associated mitochondriopathy (The American Journal of Human Genetics (2021) 108(7) (1301–1317), (S0002929721001877), (10.1016/j.ajhg.2021.05.003))

Wong, H. H., Seet, S. H., Maier, M., Gurel, A., Traspas, R. M., Lee, C., Zhang, S., Talim, B., Loh, A. Y. T., Chia, C. Y., Teoh, T. S., Sng, D., Rensvold, J., Unal, S., Shishkova, E., Cepni, E., Nathan, F. M., Sirota, F. L., Liang, C. & Yarali, N. & 52 others, Simsek-Kiper, P. O., Mitani, T., Ceylaner, S., Arman-Bilir, O., Mbarek, H., Gumruk, F., Efthymiou, S., Çïmen, D. U., Georgiadou, D., Sotiropoulou, K., Houlden, H., Paul, F., Pehlivan, D., Lainé, C., Chai, G., Ali, N. A., Choo, S. C., Keng, S. S., Boisson, B., Yılmaz, E., Xue, S., Coon, J. J., Nguyen Ly, T. T., Gilani, N., Hasbini, D., Kayserili, H., Zaki, M. S., Isfort, R. J., Ordonez, N., Tripolszki, K., Bauer, P., Rezaei, N., Seyedpour, S., Khotaei, G. T., Bascom, C. C., Maroofian, R., Chaabouni, M., Alsubhi, A., Eyaid, W., Işıkay, S., Gleeson, J. G., Lupski, J. R., Casanova, J. L., Pagliarini, D. J., Akarsu, N. A., Maurer-Stroh, S., Cetinkaya, A., Bertoli-Avella, A., Mathuru, A. S., Ho, L., Bard, F. A. & Reversade, B., Jul 1 2021, In: American journal of human genetics. 108, 7, p. 1356 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

1 Scopus citations

Kinases/Phosphatases | Protein tyrosine phosphatases

Pagliarini, D. J., Robinson, F. L., Worby, C. A. & Dixon, J. E., Jul 29 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 6. p. 377-383 7 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen-storage-associated mitochondriopathy

Wong, H. H., Seet, S. H., Maier, M., Gurel, A., Traspas, R. M., Lee, C., Zhang, S., Talim, B., Loh, A. Y. T., Chia, C. Y., Teoh, T. S., Sng, D., Rensvold, J., Unal, S., Shishkova, E., Cepni, E., Nathan, F. M., Sirota, F. L., Liang, C. & Yarali, N. & 52 others, Simsek-Kiper, P. O., Mitani, T., Ceylaner, S., Arman-Bilir, O., Mbarek, H., Gumruk, F., Efthymiou, S., Uğurlu Çi̇men, D., Georgiadou, D., Sotiropoulou, K., Houlden, H., Paul, F., Pehlivan, D., Lainé, C., Chai, G., Ali, N. A., Choo, S. C., Keng, S. S., Boisson, B., Yılmaz, E., Xue, S., Coon, J. J., Ly, T. T. N., Gilani, N., Hasbini, D., Kayserili, H., Zaki, M. S., Isfort, R. J., Ordonez, N., Tripolszki, K., Bauer, P., Rezaei, N., Seyedpour, S., Khotaei, G. T., Bascom, C. C., Maroofian, R., Chaabouni, M., Alsubhi, A., Eyaid, W., Işıkay, S., Gleeson, J. G., Lupski, J. R., Casanova, J. L., Pagliarini, D. J., Akarsu, N. A., Maurer-Stroh, S., Cetinkaya, A., Bertoli-Avella, A., Mathuru, A. S., Ho, L., Bard, F. A. & Reversade, B., Jul 1 2021, In: American journal of human genetics. 108, 7, p. 1301-1317 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Multi-Omic Single-Shot Technology for Integrated Proteome and Lipidome Analysis

He, Y., Rashan, E. H., Linke, V., Shishkova, E., Hebert, A. S., Jochem, A., Westphall, M. S., Pagliarini, D. J., Overmyer, K. A. & Coon, J. J., Mar 9 2021, In: Analytical Chemistry. 93, 9, p. 4217-4222 6 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function

Rosier, K., McDevitt, M. T., Smet, J., Floyd, B. J., Verschoore, M., Marcaida, M. J., Bingman, C. A., Lemmens, I., Dal Peraro, M., Tavernier, J., Cravatt, B. F., Gounko, N. V., Vints, K., Monnens, Y., Bhalla, K., Aerts, L., Rashan, E. H., Vanlander, A. V., Van Coster, R. & Régal, L. & 2 others, Pagliarini, D. J. & Creemers, J. W. M., Dec 17 2021, In: iScience. 24, 12, 103460.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

The extensive and functionally uncharacterized mitochondrial phosphoproteome

Niemi, N. M. & Pagliarini, D. J., Jul 1 2021, In: Journal of Biological Chemistry. 297, 1, 100880.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae

Kemmerer, Z. A., Robinson, K. P., Schmitz, J. M., Manicki, M., Paulson, B. R., Jochem, A., Hutchins, P. D., Coon, J. J. & Pagliarini, D. J., Dec 1 2021, In: Nature communications. 12, 1, 4769.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2020

Argonaut: A Web Platform for Collaborative Multi-omic Data Visualization and Exploration

Brademan, D. R., Miller, I. J., Kwiecien, N. W., Pagliarini, D. J., Westphall, M. S., Coon, J. J. & Shishkova, E., Oct 9 2020, In: Patterns. 1, 7, 100122.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Clinico-Genetic, Imaging and Molecular Delineation of COQ8A-Ataxia: A Multicenter Study of 59 Patients

Traschütz, A., Schirinzi, T., Laugwitz, L., Murray, N. H., Bingman, C. A., Reich, S., Kern, J., Heinzmann, A., Vasco, G., Bertini, E., Zanni, G., Durr, A., Magri, S., Taroni, F., Malandrini, A., Baets, J., de Jonghe, P., de Ridder, W., Bereau, M. & Demuth, S. & 22 others, Ganos, C., Basak, A. N., Hanagasi, H., Kurul, S. H., Bender, B., Schöls, L., Grasshoff, U., Klopstock, T., Horvath, R., van de Warrenburg, B., Burglen, L., Rougeot, C., Ewenczyk, C., Koenig, M., Santorelli, F. M., Anheim, M., Munhoz, R. P., Haack, T., Distelmaier, F., Pagliarini, D. J., Puccio, H. & Synofzik, M., Aug 1 2020, In: Annals of neurology. 88, 2, p. 251-263 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy

Stefely, J. A., Zhang, Y., Freiberger, E. C., Kwiecien, N. W., Thomas, H. E., Davis, A. M., Lowry, N. D., Vincent, C. E., Shishkova, E., Clark, N. A., Medvedovic, M., Coon, J. J., Pagliarini, D. J. & Mercer, C. A., 2020, In: Autophagy. 16, 12, p. 2219-2237 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Pathogenic Bi-allelic Mutations in NDUFAF8 Cause Leigh Syndrome with an Isolated Complex I Deficiency

Alston, C. L., Veling, M. T., Heidler, J., Taylor, L. S., Alaimo, J. T., Sung, A. Y., He, L., Hopton, S., Broomfield, A., Pavaine, J., Diaz, J., Leon, E., Wolf, P., McFarland, R., Prokisch, H., Wortmann, S. B., Bonnen, P. E., Wittig, I., Pagliarini, D. J. & Taylor, R. W., Jan 2 2020, In: American journal of human genetics. 106, 1, p. 92-101 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Quantitative shotgun proteome analysis by direct infusion

Meyer, J. G., Niemi, N. M., Pagliarini, D. J. & Coon, J. J., Dec 2020, In: Nature Methods. 17, 12, p. 1222-1228 7 p.

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Systems Biochemistry Approaches to Defining Mitochondrial Protein Function

Sung, A. Y., Floyd, B. J. & Pagliarini, D. J., Apr 7 2020, In: Cell metabolism. 31, 4, p. 669-678 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

23 Scopus citations

2019

ADCK3/COQ8A: the choice target of the UbiB protein kinase-like family

Asquith, C. R. M., Murray, N. H. & Pagliarini, D. J., Oct 1 2019, In: Nature Reviews Drug Discovery. 18, 11, p. 815 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

11 Scopus citations

An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis

Lohman, D. C., Aydin, D., Von Bank, H. C., Smith, R. W., Linke, V., Weisenhorn, E., McDevitt, M. T., Hutchins, P., Wilkerson, E. M., Wancewicz, B., Russell, J., Stefely, M. S., Beebe, E. T., Jochem, A., Coon, J. J., Bingman, C. A., Dal Peraro, M. & Pagliarini, D. J., Feb 21 2019, In: Molecular cell. 73, 4, p. 763-774.e10

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER-mitochondria contacts

Subramanian, K., Jochem, A., Vasseur, M. L., Lewis, S., Paulson, B. R., Reddy, T. R., Russell, J. D., Coon, J. J., Pagliarini, D. J. & Nunnari, J., 2019, In: Journal of Cell Biology. 218, 4, p. 1352-1368 17 p.

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at complex I in pancreatic -cells

Gregg, T., Sdao, S. M., Dhillon, R. S., Rensvold, J. W., Lewandowski, S. L., Pagliarini, D. J., Denu, J. M. & Merrins, M. J., Mar 22 2019, In: Journal of Biological Chemistry. 294, 12, p. 4656-4666 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis

Niemi, N. M., Wilson, G. M., Overmyer, K. A., Vögtle, F. N., Myketin, L., Lohman, D. C., Schueler, K. L., Attie, A. D., Meisinger, C., Coon, J. J. & Pagliarini, D. J., Dec 1 2019, In: Nature communications. 10, 1, 3197.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation

Seim, G. L., Britt, E. C., John, S. V., Yeo, F. J., Johnson, A. R., Eisenstein, R. S., Pagliarini, D. J. & Fan, J., Jul 1 2019, In: Nature Metabolism. 1, 7, p. 731-742 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

102 Scopus citations

2018

A path to the powerhouse: systems-to-structure approaches for studying mitochondrial proteins

Pagliarini, D. J., Aug 2018, In: Protein Science. 27, 8, p. 1518-1525 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family

Reidenbach, A. G., Kemmerer, Z. A., Aydin, D., Jochem, A., McDevitt, M. T., Hutchins, P. D., Stark, J. L., Stefely, J. A., Reddy, T., Hebert, A. S., Wilkerson, E. M., Johnson, I. E., Bingman, C. A., Markley, J. L., Coon, J. J., Dal Peraro, M. & Pagliarini, D. J., Feb 15 2018, In: Cell Chemical Biology. 25, 2, p. 154-165.e11

Research output: Contribution to journal › Article › peer-review

Open Access

55 Scopus citations

DNA Polymerase θ Increases Mutational Rates in Mitochondrial DNA

Wisnovsky, S., Sack, T., Pagliarini, D. J., Laposa, R. R. & Kelley, S. O., Apr 20 2018, In: ACS Chemical Biology. 13, 4, p. 900-908 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes

Jha, P., McDevitt, M. T., Halilbasic, E., Williams, E. G., Quiros, P. M., Gariani, K., Sleiman, M. B., Gupta, R., Ulbrich, A., Jochem, A., Coon, J. J., Trauner, M., Pagliarini, D. J. & Auwerx, J., Jun 27 2018, In: Cell Systems. 6, 6, p. 709-721.e6

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Identification and Quantification of Murine Mitochondrial Proteoforms Using an Integrated Top-Down and Intact-Mass Strategy

Schaffer, L. V., Rensvold, J. W., Shortreed, M. R., Cesnik, A. J., Jochem, A., Scalf, M., Frey, B. L., Pagliarini, D. J. & Smith, L. M., Oct 5 2018, In: Journal of Proteome Research. 17, 10, p. 3526-3536 11 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Multi-omics Reveal Specific Targets of the RNA-Binding Protein Puf3p and Its Orchestration of Mitochondrial Biogenesis

Lapointe, C. P., Stefely, J. A., Jochem, A., Hutchins, P. D., Wilson, G. M., Kwiecien, N. W., Coon, J. J., Wickens, M. & Pagliarini, D. J., Jan 24 2018, In: Cell Systems. 6, 1, p. 125-135.e6

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species

Jha, P., McDevitt, M. T., Gupta, R., Quiros, P. M., Williams, E. G., Gariani, K., Sleiman, M. B., Diserens, L., Jochem, A., Ulbrich, A., Coon, J. J., Auwerx, J. & Pagliarini, D. J., Jun 27 2018, In: Cell Systems. 6, 6, p. 722-733.e6

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

2017

Biochemistry of Mitochondrial Coenzyme Q Biosynthesis

Stefely, J. A. & Pagliarini, D. J., Oct 2017, In: Trends in biochemical sciences. 42, 10, p. 824-843 20 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

233 Scopus citations

Erythropoietin signaling regulates heme biosynthesis

Chung, J., Wittig, J. G., Ghamari, A., Maeda, M., Dailey, T. A., Bergonia, H., Kafina, M. D., Coughlin, E. E., Minogue, C. E., Hebert, A. S., Li, L., Kaplan, J., Lodish, H. F., Bauer, D. E., Orkin, S. H., Cantor, A. B., Maeda, T., Phillips, J. D., Coon, J. J. & Pagliarini, D. J. & 2 others, Dailey, H. A. & Paw, B. H., May 29 2017, In: eLife. 6, e24767.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase

Guo, X., Niemi, N. M., Coon, J. J. & Pagliarini, D. J., Jul 14 2017, In: Journal of Biological Chemistry. 292, 28, p. 11751-11759 9 p.

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23 Scopus citations

Dave Pagliarini

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