Daniel Morgensztern

2019

An open-label phase IB study to evaluate GSK3052230 in combination with paclitaxel and carboplatin, or docetaxel, in FGFR1-amplified non-small cell lung cancer

Morgensztern, D., Karaseva, N., Felip, E., Delgado, I., Burdaeva, O., Dómine, M., Lara, P., Paik, P. K., Lassen, U., Orlov, S., Trigo, J., Shomova, M., Baker-Neblett, K., Vasquez, J., Wang, X., Yan, L., Mitrica, I., DeYoung, M. P. & Garrido, P., Oct 2019, In: Lung Cancer. 136, p. 74-79 6 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

A phase I/IB trial of the vegfr-sparing multikinase ret inhibitor RXDX-105

Drilon, A., Fu, S., Patel, M. R., Fakih, M., Wang, D., Olszanski, A. J., Morgensztern, D., Liu, S. V., Cho, B. C., Bazhenova, L., Rodriguez, C. P., Doebele, R. C., Wozniak, A., Reckamp, K. L., Seery, T., Nikolinakos, P., Hu, Z., Oliver, J. W., Trone, D. & McArthur, K. & 3 others, Patel, R., Multani, P. S. & Ahn, M. J., Mar 1 2019, In: Cancer discovery. 9, 3, p. 384-395 12 p.

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Association between depth of response and survival in patients with advanced-stage non–small cell lung cancer treated with first-line chemotherapy

Morgensztern, D., Ko, A., O’Brien, M., Ong, T. J., Waqar, S. N., Socinski, M. A., Postmus, P. E. & Bhore, R., Jul 15 2019, In: Cancer. 125, 14, p. 2394-2399 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Cell-Free DNA in Cancer Diagnosis and Follow Up

Ferreira, B. P. & Morgensztern, D., Jan 1 2019, Cancer Genomics for the Clinician. Springer Publishing Company, p. 115-126 12 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Circulating tumor DNA profiling in small-cell lung cancer identifies potentially targetable alterations

Devarakonda, S., Sankararaman, S., Herzog, B. H., Gold, K. A., Waqar, S. N., Ward, J. P., Raymond, V. M., Lanman, R. B., Chaudhuri, A. A., Owonikoko, T. K., Li, B. T., Poirier, J. T., Rudin, C. M., Govindan, R. & Morgensztern, D., Oct 15 2019, In: Clinical Cancer Research. 25, 20, p. 6119-6126 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Efficacy and safety of rovalpituzumab tesirine in third-line and beyond patients with DLL3-expressing, relapsed/refractory small-cell lung cancer: Results from the phase II TrINITY study

Morgensztern, D., Besse, B., Greillier, L., Santana-Davila, R., Ready, N., Hann, C. L., Glisson, B. S., Farago, A. F., Dowlati, A., Rudin, C. M., Le Moulec, S., Lally, S., Yalamanchili, S., Wolf, J., Govindan, R. & Carbone, D. P., Dec 1 2019, In: Clinical Cancer Research. 25, 23, p. 6958-6966 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

244 Scopus citations

KEYNOTE-042 and the role for single agent pembrolizumab in patients with PD-L1 tumor proportion score 1-49%

Morgensztern, D., 2019, In: Journal of Thoracic Disease. 11, p. S1963-S1965

Research output: Contribution to journal › Comment/debate

Open Access

9 Scopus citations

RRx-001 followed by platinum plus etoposide in patients with previously treated small-cell lung cancer

Morgensztern, D., Rose, M., Waqar, S. N., Morris, J., Ma, P. C., Reid, T., Brzezniak, C. E., Zeman, K. G., Padmanabhan, A., Hirth, J. A., I. Spira, A., Trepel, J. B. & Padda, S. K., Jul 30 2019, In: British Journal of Cancer. 121, 3, p. 211-217 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

2018

ABOUND.2L+: A randomized phase 2 study of nanoparticle albumin-bound paclitaxel with or without CC-486 as second-line treatment for advanced nonsquamous non-small cell lung cancer (NSCLC)

on behalf of the ABOUND.2L+ Investigators, Dec 15 2018, In: Cancer. 124, 24, p. 4667-4675 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Early Mortality in Patients Undergoing Adjuvant Chemotherapy for Non–Small Cell Lung Cancer

Morgensztern, D., Samson, P. S., Waqar, S. N., Devarakonda, S., Robinson, C. G., Govindan, R. & Puri, V., Apr 2018, In: Journal of Thoracic Oncology. 13, 4, p. 543-549 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

First-in-human phase I, dose-escalation and -expansion study of telisotuzumab vedotin, an antibody–drug conjugate targeting c-Met, in patients with advanced solid tumors

Strickler, J. H., Weekes, C. D., Nemunaitis, J., Ramanathan, R. K., Heist, R. S., Morgensztern, D., Angevin, E., Bauer, T. M., Yue, H., Motwani, M., Parikh, A., Reilly, E. B., Afar, D., Naumovski, L. & Kelly, K., Nov 20 2018, In: Journal of Clinical Oncology. 36, 33, p. 3298-3306 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

106 Scopus citations

Immunogenicity of Influenza Vaccination in Patients with Cancer

Waqar, S. N., Boehmer, L., Morgensztern, D., Wang-Gillam, A., Sorscher, S., Lawrence, S., Gao, F., Guebert, K., Williams, K. & Govindan, R., 2018, In: American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 3, p. 248-253 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Lorlatinib: a new-generation drug for ALK-positive NSCLC

Waqar, S. N. & Morgensztern, D., Dec 2018, In: The Lancet Oncology. 19, 12, p. 1555-1557 3 p.

Research output: Contribution to journal › Comment/debate

14 Scopus citations

Mutational Events in Lung Cancer

Morgensztern, D., Devarakonda, S., Mitsudomi, T., Maher, C. & Govindan, R., Jan 1 2018, IASLC Thoracic Oncology. Elsevier, p. 95-103.e2

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

7 Scopus citations

NCCN guidelines® insights: Small cell lung cancer, version 2.2018 featured updates to the NCCN guidelines

Kalemkerian, G. P., Loo, B. W., Akerley, W., Attia, A., Bassetti, M., Boumber, Y., Decker, R., Dobelbower, M. C., Dowlati, A., Downey, R. J., Florsheim, C., Ganti, A. K. P., Grecula, J. C., Gubens, M. A., Hann, C. L., Hayman, J. A., Heist, R. S., Koczywas, M., Merritt, R. E. & Mohindra, N. & 11 others, Molina, J., Moran, C. A., Morgensztern, D., Pokharel, S., Portnoy, D. C., Rhodes, D., Rusthoven, C., Santana-Davila, R., Williams, C. C., Hoffmann, K. G. & Hughes, M., Oct 1 2018, In: JNCCN Journal of the National Comprehensive Cancer Network. 16, 10, p. 1171-1182 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

217 Scopus citations

Non–small-cell Lung Cancer With Brain Metastasis at Presentation

Waqar, S. N., Samson, P. P., Robinson, C. G., Bradley, J., Devarakonda, S., Du, L., Govindan, R., Gao, F., Puri, V. & Morgensztern, D., Jul 2018, In: Clinical Lung Cancer. 19, 4, p. e373-e379

Research output: Contribution to journal › Article › peer-review

Open Access

178 Scopus citations

Paraneoplastic syndromes

Morgensztern, D., Waqar, S. N. & Govindan, R., Nov 16 2018, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 1998-2007 10 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Percutaneous Image-Guided Ablation in the Treatment of Osseous Metastases from Non-small Cell Lung Cancer

Ma, Y., Wallace, A. N., Waqar, S. N., Morgensztern, D., Madaelil, T. P., Tomasian, A. & Jennings, J. W., May 1 2018, In: Cardiovascular and Interventional Radiology. 41, 5, p. 726-733 8 p.

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer

Wagner, A. H., Devarakonda, S., Skidmore, Z. L., Krysiak, K., Ramu, A., Trani, L., Kunisaki, J., Masood, A., Waqar, S. N., Spies, N. C., Morgensztern, D., Waligorski, J., Ponce, J., Fulton, R. S., Maggi, L. B., Weber, J. D., Watson, M. A., O’Conor, C. J., Ritter, J. H. & Olsen, R. R. & 10 others, Cheng, H., Mukhopadhyay, A., Can, I., Cessna, M. H., Oliver, T. G., Mardis, E. R., Wilson, R. K., Griffith, M., Griffith, O. L. & Govindan, R., Dec 1 2018, In: Nature communications. 9, 1, 3787.

Research output: Contribution to journal › Article › peer-review

Open Access

115 Scopus citations

Role of immune checkpoint blockers in patients with EGFR mutation

Ward, J. & Morgensztern, D., Dec 2018, In: Translational Lung Cancer Research. 7, p. S385-S387

Research output: Contribution to journal › Editorial

Open Access

2 Scopus citations

The biology and management of non-small cell lung cancer

Herbst, R. S., Morgensztern, D. & Boshoff, C., Jan 24 2018, In: Nature. 553, 7689, p. 446-454 9 p.

Research output: Contribution to journal › Review article › peer-review

3537 Scopus citations

2017

Adjuvant Chemotherapy Is Associated With Improved Survival in Locally Invasive Node Negative Non-Small Cell Lung Cancer

Ahmad, U., Crabtree, T. D., Patel, A. P., Morgensztern, D., Robinson, C. G., Krupnick, A. S., Kreisel, D., Jones, D. R., Patterson, G. A., Meyers, B. F. & Puri, V., Jul 2017, In: Annals of Thoracic Surgery. 104, 1, p. 303-307 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Defining the Ideal Time Interval Between Planned Induction Therapy and Surgery for Stage IIIA Non-Small Cell Lung Cancer

Samson, P., Crabtree, T. D., Robinson, C. G., Morgensztern, D., Broderick, S., Krupnick, A. S., Kreisel, D., Patterson, G. A., Meyers, B. & Puri, V., Apr 1 2017, In: Annals of Thoracic Surgery. 103, 4, p. 1070-1075 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Evolving Treatment Options for Lung Cancer

Morgensztern, D. & Herbst, R. S., Feb 1 2017, In: Hematology/Oncology Clinics of North America. 31, 1, p. xiii-xiv

Research output: Contribution to journal › Editorial

1 Scopus citations

Immunotherapy in Lung Cancer

Du, L., Herbst, R. S. & Morgensztern, D., Feb 1 2017, In: Hematology/Oncology Clinics of North America. 31, 1, p. 131-141 11 p.

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

nab-paclitaxel/carboplatin induction in squamous NSCLC: Longitudinal quality of life while on chemotherapy

ABOUND.sqm investigators, Oct 30 2017, In: Lung Cancer: Targets and Therapy. 8, p. 207-216 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas

Oronsky, B., Ma, P. C., Morgensztern, D. & Carter, C. A., Dec 2017, In: Neoplasia (United States). 19, 12, p. 991-1002 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

516 Scopus citations

Rovalpituzumab tesirine, a DLL3-targeted antibody-drug conjugate, in recurrent small-cell lung cancer: a first-in-human, first-in-class, open-label, phase 1 study

SCRX16-001 investigators, Jan 1 2017, In: The Lancet Oncology. 18, 1, p. 42-51 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

482 Scopus citations

Systemic Treatment of Brain Metastases

Waqar, S. N., Morgensztern, D. & Govindan, R., Feb 1 2017, In: Hematology/Oncology Clinics of North America. 31, 1, p. 157-176 20 p.

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Treatment advances in small cell lung cancer (SCLC)

Waqar, S. N. & Morgensztern, D., Dec 2017, In: Pharmacology and Therapeutics. 180, p. 16-23 8 p.

Research output: Contribution to journal › Review article › peer-review

155 Scopus citations

2016

Adjuvant chemotherapy for patients with T2N0M0 NSCLC

Morgensztern, D., Du, L., Waqar, S. N., Patel, A., Samson, P., Devarakonda, S., Gao, F., Robinson, C. G., Bradley, J., Baggstrom, M., Masood, A., Govindan, R. & Puri, V., 2016, In: Journal of Thoracic Oncology. 11, 10, p. 1729-1735 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

82 Scopus citations

A Phase i Trial of Temsirolimus and Pemetrexed in Patients with Advanced Non-Small Cell Lung Cancer

Waqar, S. N., Baggstrom, M. Q., Morgensztern, D., Williams, K., Rigden, C. & Govindan, R., Apr 1 2016, In: Chemotherapy. 61, 3, p. 144-147 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Delayed nausea and vomiting from carboplatin doublet chemotherapy

Waqar, S. N., Mann, J., Baggstrom, M. Q., Waqar, M. A., Chitneni, P., Williams, K., Gao, F., Morgensztern, D. & Govindan, R., Jun 2 2016, In: Acta Oncologica. 55, 6, p. 700-704 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Immune checkpoint inhibition in patients with brain metastases

Johanns, T., Waqar, S. N. & Morgensztern, D., Oct 2016, In: Annals of Translational Medicine. 4, S9.

Research output: Contribution to journal › Editorial

Open Access

10 Scopus citations

Multimodality therapy for NSCLC

Du, L., Waqar, S. N. & Morgensztern, D., Jan 1 2016, Cancer Treatment and Research. Kluwer Academic Publishers, p. 151-163 13 p. (Cancer Treatment and Research; vol. 170).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

5 Scopus citations

Nivolumab and Pembrolizumab for Non-Small Cell Lung Cancer

Morgensztern, D. & Herbst, R. S., Aug 1 2016, In: Clinical Cancer Research. 22, 15, p. 3713-3717 5 p.

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Patterns of care in hilar node-positive (N1) non-small cell lung cancer: A missed treatment opportunity? Read at the 41st Annual Meeting of the Western Thoracic Surgical Association, Whistler, British Columbia, Canada, June 25, 2015.

Bott, M. J., Patel, A. P., Verma, V., Crabtree, T. D., Morgensztern, D., Robinson, C. G., Colditz, G. A., Waqar, S., Kreisel, D., Krupnick, A. S., Patterson, G. A., Broderick, S., Meyers, B. F. & Puri, V., Jun 1 2016, In: Journal of Thoracic and Cardiovascular Surgery. 151, 6, p. 1549-1558.e2

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Pneumonectomy for Clinical Stage IIIA Non-Small Cell Lung Cancer: The Effect of Neoadjuvant Therapy

Broderick, S. R., Patel, A. P., Crabtree, T. D., Bell, J. M., Morgansztern, D., Robinson, C. G., Kreisel, D., Krupnick, A. S., Patterson, G. A., Meyers, B. F. & Puri, V., Feb 1 2016, In: Annals of Thoracic Surgery. 101, 2, p. 451-458 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Precision medicine in lung cancer: The battle continues

Waqar, S. N. & Morgensztern, D., 2016, In: Journal of Thoracic Disease. 8, 11, p. 2991-2993 3 p.

Research output: Contribution to journal › Editorial

2 Scopus citations

Role for adjuvant chemotherapy in patients with resected small cell lung cancer

Du, L., Waqar, S. N. & Morgensztern, D., 2016, In: Journal of Thoracic Disease. 8, 8, p. 1891-1892 2 p.

Research output: Contribution to journal › Editorial

1 Scopus citations

2015

Brain Metastases at presentation in patients with non-small cell lung cancer

Waqar, S. N., Waqar, S. H., Trinkaus, K., Gadea, C. A., Robinson, C. G., Bradley, J., Watson, M. A., Puri, V., Govindan, R. & Morgensztern, D., Sep 3 2015, In: American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 1, p. 36-40 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Chemotherapy for advanced-stage non-small cell lung cancer

Du, L. & Morgensztern, D., Sep 1 2015, In: Cancer Journal (United States). 21, 5, p. 366-370 5 p.

Research output: Contribution to journal › Review article › peer-review

50 Scopus citations

Clinical next-generation sequencing in patients with non-small cell lung cancer

Hagemann, I. S., Devarakonda, S., Lockwood, C. M., Spencer, D. H., Guebert, K., Bredemeyer, A. J., Al-Kateb, H., Nguyen, T. T., Duncavage, E. J., Cottrell, C. E., Kulkarni, S., Nagarajan, R., Seibert, K., Baggstrom, M., Waqar, S. N., Pfeifer, J. D., Morgensztern, D. & Govindan, R., Feb 1 2015, In: Cancer. 121, 4, p. 631-639 9 p.

Research output: Contribution to journal › Article › peer-review

193 Scopus citations

EGFR mutations in non-small-cell lung cancer: Find, divide, and conquer

Morgensztern, D., Politi, K. & Herbst, R. S., May 1 2015, In: JAMA oncology. 1, 2, p. 146-148 3 p.

Research output: Contribution to journal › Editorial

32 Scopus citations

Genomic alterations in lung adenocarcinoma

Devarakonda, S., Morgensztern, D. & Govindan, R., Jul 1 2015, In: The Lancet Oncology. 16, 7, p. e342-e351

Research output: Contribution to journal › Review article › peer-review

335 Scopus citations

Immunotherapy for non-small cell lung cancer: Are we on the cusp of a new era?

Waqar, S. N. & Morgensztern, D., Aug 1 2015, In: Expert Review of Clinical Immunology. 11, 8, p. 871-873 3 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

8 Scopus citations

MET mutation associated with responsiveness to crizotinib

Waqar, S. N., Morgensztern, D. & Sehn, J., May 30 2015, In: Journal of Thoracic Oncology. 10, 5, p. e29-e31

Research output: Contribution to journal › Letter › peer-review

Open Access

80 Scopus citations

Molecularly targeted therapies in non-small-cell lung cancer annual update 2014

Morgensztern, D., Campo, M. J., Dahlberg, S. E., Doebele, R. C., Garon, E., Gerber, D. E., Goldberg, S. B., Hammerman, P. S., Heist, R. S., Hensing, T., Horn, L., Ramalingam, S. S., Rudin, C. M., Salgia, R., Sequist, L. V., Shaw, A. T., Simon, G. R., Somaiah, N., Spigel, D. R. & Wrangle, J. & 4 others, Johnson, D., Herbst, R. S., Bunn, P. & Govindan, R., Jan 13 2015, In: Journal of Thoracic Oncology. 10, 1, p. S1-S63

Research output: Contribution to journal › Article › peer-review

Open Access

124 Scopus citations

Multidisciplinary treatment for stage IIIA non-small cell lung cancer: Does institution type matter?

Samson, P., Patel, A., Crabtree, T. D., Morgensztern, D., Robinson, C. G., Colditz, G. A., Waqar, S., Kreisel, D., Krupnick, A. S., Patterson, G. A., Broderick, S., Meyers, B. F. & Puri, V., Nov 2015, In: Annals of Thoracic Surgery. 100, 5, p. 1773-1779 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Paraneoplastic syndromes

Govindan, R., Stinchcombe, T. E. & Morgensztern, D., Jan 7 2015, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology: Tenth Edition. Wolters Kluwer Health Adis (ESP)

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Daniel Morgensztern

Research output

Search results