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Personal profile

Research interests

Dr. Marcus’ laboratory builds imaging informatics and analysis tools, with a particular focus on neuroimaging. The laboratory has developed the XNAT imaging informatics platform (www.xnat.org), open source software used in facilities around the world to manage and share neuroimaging and related data. Dr. Marcus directs a number of service cores at the University, including for the Alzheimer’s Disease Research Center, the Intellectual Developmental Disabilities Research Center, and NINDS Center Core for Brain Imaging. He’s also an investigator in several NIH-backed initiatives to develop a national informatics infrastructure, including the Biomedical Informatics Research Network (BIRN), the National Alliance for Medical Image Computing (NAMIC), and Informatics for Integrating Biology and the Bedside (I2B2).

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Projects

Connectome Coordination Facility II

Marcus, D. & Van Essen, D.

04/15/2001/31/21

Project: Research

NINDS CENTER CORE FOR BRAIN IMAGING

Hershey, T., Marcus, D., Marcus, D. & RAICHLE, M.

07/1/1606/30/17

Project: Research

Connectome Coordination Facility

Marcus, D. & Van Essen, D.

07/1/1503/31/16

Project: Research

NINDS Center Core for Brain Imaging

Marcus, D. & MINTUN, M.

12/1/1011/30/11

Project: Research

Research Output

Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease

Dominantly Inherited Alzheimer Network (DIAN) & PREVENT-AD Research Group, Jan 1 2020, (Accepted/In press) In : Biological Psychiatry.

Research output: Contribution to journalArticle

  • Automatic detection of contrast enhancement in T1-weighted brain MRI of human adults

    Milchenko, M., Lamontagne, P. & Marcus, D., Jan 1 2020, Medical Imaging 2020: Computer-Aided Diagnosis. Hahn, H. K. & Mazurowski, M. A. (eds.). SPIE, 113140F. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11314).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  • Preprocessing of clinical neuro-oncology MRI studies for big data applications

    Chakrabarty, S., Lamontagne, P., Marcus, D. S. & Milchenko, M., Jan 1 2020, Medical Imaging 2020: Imaging Informatics for Healthcare, Research, and Applications. Chen, P-H. & Deserno, T. M. (eds.). SPIE, 1131809. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11318).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  • SNIPR: Stroke Neuroimaging Phenotype Repository

    Mohammadian Foroushani, H., Dhar, R., Chen, Y., Gurney, J., Hamzehloo, A., Lee, J. M. & Marcus, D. S., Jan 1 2020, Medical Imaging 2020: Imaging Informatics for Healthcare, Research, and Applications. Chen, P-H. & Deserno, T. M. (eds.). SPIE, 113180B. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11318).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  • An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

    the Dominantly Inherited Alzheimer Network (DIAN), Nov 1 2019, In : Nature neuroscience. 22, 11, p. 1903-1912 10 p.

    Research output: Contribution to journalArticle

  • 11 Scopus citations