Keyphrases
Nitrophenyl
100%
Urazole
75%
Boronic Acid
75%
Sulfone
75%
β-lactamase
75%
KPC-2
75%
Pyridine
50%
Preferred Basis
24%
N-BuLi
24%
Thiazolidine-2,4-dione
24%
Primary Amines
24%
Electronegative
24%
Tert-butyl
24%
Library Synthesis
24%
Esters
24%
Active Sites
20%
β-lactamase Inhibitor
20%
M-value
13%
Oxyanion Hole
13%
Active Site Interaction
6%
Water Pocket
6%
N170
6%
Reversible Covalent
6%
Boronic Acid Derivatives
6%
Edge-to-face Interaction
6%
Carbapenem Antibiotics
6%
Clavulanic Acid
6%
Inactivation Rate Constant
6%
Carbapenemases
6%
Tazobactam
6%
Enamine Intermediate
6%
Sulbactam
6%
Acyl-coenzyme A
6%
Compound 3
6%
Carbonyl
6%
Carbapenemase
6%
Covalently Bound
6%
Hydroxyl
6%
Deacylation
6%
Inhibition Mechanism
6%
Covalent Interaction
6%
Boron
6%
Carboxyl
6%
Aromatic Ring
6%
Biochemistry, Genetics and Molecular Biology
Crystal Structure
75%
Active Site
75%
Sulfone
75%
Oxyanion Hole
37%
Inactivation Rate Constant
18%
N170
18%
Sulbactam
18%
Deacylation
18%
Tazobactam
18%
Enzyme
18%
Pharmacology, Toxicology and Pharmaceutical Science
Boronic Acid Derivative
75%
Penicillinase
75%
Sulfone
75%
Carbapenemase
21%
Oxyanion
21%
Sulbactam
10%
Enamine
10%
Tazobactam
10%
Clavulanic Acid
10%
Carbapenem Derivative
10%