Personal profile
Research interests
The Leung Lab is focused on developing a mechanistic understanding of host-pathogen interactions that contribute to viral pathogenesis through immune evasion, replication, and spread. We use a multidisciplinary approach to characterize select non-segmented negative sense RNA viruses, including respiratory syncytial virus and Ebola virus, to identify critical targets that can be used as a basis to develop therapeutics or vaccine candidates.
Mentoring
My goal is to create a supportive and inclusive training environment for a diverse group of individuals and to develop the next generation of scientists. I provide trainees with the opportunities to grow their scientific and professional skills while performing competitive research. Training is tailored to the needs of each individual and is dependent on open and effective communication to achieve their career goals while supporting the overall goals of the research program.
Available to Mentor:
- PhD Students
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Collaborations and top research areas from the last five years
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Multiple LDLR family members act as entry receptors for yellow fever virus
Chong, Z., Hui, S., Qiu, X., Palakurty, S., Sariol, A., Kaszuba, T., Nguyen, M. N., Li, P., Raju, S., Hall, P. D., Nelson, C. A., Baltazar-Perez, I., Price, D. A., Rothlauf, P. W., Crowe, J. E., Whelan, S. P. J., Leung, D. W., Amarasinghe, G. K., Bailey, A. L. & Fremont, D. H. & 1 others, , Jan 1 2026, In: Nature. 649, 8095, p. 173-182 10 p.Research output: Contribution to journal › Article › peer-review
3 Link opens in a new tab Scopus citations -
25 Years of Ebola Virus VP35 Research
Uwase, G., Leung, D. W. & Amarasinghe, G. K., Nov 1 2025, In: Journal of Molecular Biology. 437, 21, 169366.Research output: Contribution to journal › Review article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
A protein-proximity screen reveals Ebola virus co-opts the mRNA decapping complex through the scaffold protein EDC4
Donahue, C. J., Kesari, A. S., Thakur, N., Wang, L., Stubbs, S. H., Williams, C. G., Sharma, S. B., Kirby, C. D., Leung, D. W., Aryal, U. K., Basler, C. F., LaCount, D. J. & Davey, R. A., Dec 2025, In: Nature communications. 16, 1, 8485.Research output: Contribution to journal › Article › peer-review
Open Access -
Biophysical Characterization of Protein-Protein Interactions in Respiratory Syncytial Virus Infections
Wagner, N. D., Price, D. A. & Leung, D. W., 2025, Methods in Molecular Biology. Humana Press Inc., p. 211-232 22 p. (Methods in Molecular Biology; vol. 2948).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer’s disease ligands
Greven, J. A., Wydra, J. R., Greer, R. A., Zhi, C., Price, D. A., Svoboda, J. D., Camitta, C. L. M., Washington, M., Leung, D. W., Song, Y., Alexander-Brett, J. & Brett, T. J., Dec 2025, In: Molecular neurodegeneration. 20, 1, 3.Research output: Contribution to journal › Article › peer-review
Open Access17 Link opens in a new tab Scopus citations