Research output per year
Research output per year
Personal profile
Research interests
The Leung Lab is focused on developing a mechanistic understanding of host-pathogen interactions that contribute to viral pathogenesis through immune evasion, replication, and spread. We use a multidisciplinary approach to characterize select non-segmented negative sense RNA viruses, including respiratory syncytial virus and Ebola virus, to identify critical targets that can be used as a basis to develop therapeutics or vaccine candidates.
Mentoring
My goal is to create a supportive and inclusive training environment for a diverse group of individuals and to develop the next generation of scientists. I provide trainees with the opportunities to grow their scientific and professional skills while performing competitive research. Training is tailored to the needs of each individual and is dependent on open and effective communication to achieve their career goals while supporting the overall goals of the research program.
Available to Mentor:
- PhD/MSTP Students
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer’s disease ligands
Greven, J. A., Wydra, J. R., Greer, R. A., Zhi, C., Price, D. A., Svoboda, J. D., Camitta, C. L. M., Washington, M., Leung, D. W., Song, Y., Alexander-Brett, J. & Brett, T. J., Dec 2025, In: Molecular neurodegeneration. 20, 1, 3.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular basis for human respiratory syncytial virus transcriptional regulator NS1 interactions with MED25
Kalita, P., Khatavkar, O., Uwase, G., Korshunova, Y., Hu, Y., Wagner, N. D., Xu, J., Pan, J., Nix, J. C., Gross, M. L., Brody, S. L., Borek, D., Amarasinghe, G. K., Payton, J. E. & Leung, D. W., Dec 2025, In: Nature communications. 16, 1, 2883.Research output: Contribution to journal › Article › peer-review
Open Access -
A Flexible, Quantitative Plasmonic-Fluor Lateral Flow Assay for the Rapid Detection of Orthoebolavirus zairense and Orthoebolavirus sudanense
Qavi, A. J., Jiang, Q., Aman, M. J., Vu, H., Zetlin, L., Dye, J. M., Froude, J. W., Leung, D. W., Holtsberg, F., Crick, S. L. & Amarasinghe, G. K., Jan 12 2024, In: ACS Infectious Diseases. 10, 1, p. 57-63 7 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Manipulating Light for the Detection of Viruses in Resource-Limited Settings
Qavi, A. J., Jiang, Q., Javad Aman, M., Vu, H., Zetlin, L., Dye, J. M., Froude, J. W., Leung, D. W., Holtsberg, F., Crick, S. L. & Amarasinghe, G., 2024, Frontiers in Biological Detection: From Nanosensors to Systems XVI. Danielli, A., Miller, B. L. & Weiss, S. M. (eds.). SPIE, 128610B. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 12861).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
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Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab
Ming, Q., Antfolk, D., Price, D. A., Manturova, A., Medina, E., Singh, S., Mason, C., Tran, T. H., Smalley, K. S. M., Leung, D. W. & Luca, V. C., Dec 2024, In: Nature communications. 15, 1, 7513.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations