Personal profile
Research interests
Employing genetically engineered hiSPCs and mice to develop preclinical models of low grade nervous system tumors.
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Collaborations and top research areas from the last five years
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Nested pediatric low-grade glioma cerebral organoid avatars reveal glutamatergic neuron stromal growth dependency
Xu, E., Zhang, C., Rodriguez, F. J., Dahiya, S., Anastasaki, C. & Gutmann, D. H., May 2026, In: Genes and Development. 40, 9-10, p. 638-649 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Aberrant coupling of glutamate and tyrosine kinase receptors enables neuronal control of brain-tumor growth
Anastasaki, C., Mu, R., Kernan, C. M., Li, X., Barakat, R., Koleske, J. P., Gao, Y., Cobb, O. M., Lu, X., Eberhart, C. G., Phillips, J. J., Strahle, J. M., Dahiya, S., Mennerick, S. J., Rodriguez, F. J. & Gutmann, D. H., Nov 5 2025, In: Neuron. 113, 21, p. 3582-3600.e7Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Scopus citations -
Cognition and behavior in neurofibromatosis type 1: report and perspective from the Cognition and Behavior in NF1 (CABIN) Task Force
on behalf of the CABIN Task Force, Gutmann, D. H., Anastasaki, C., Gupta, A., Hou, Y., Morris, S. M., Payne, J. M., Raber, J., Tomchik, S. M., Van Aelst, L., Walker, J. A. & Yohay, K. H., 2025, In: Genes and Development. 39, 9-10, p. 541-554 14 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Link opens in a new tab Scopus citations -
Corrigendum for Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins [J Clin Invest. 2021;131(1):e139807. DOI:10.1172/JCI139807]
Mo, J., Anastasaki, C., Chen, Z., Shipman, T., Papke, J., Yin, K., Gutmann, D. H. & Le, L. Q., Oct 15 2025, In: Journal of Clinical Investigation. 135, 20, e199700.Research output: Contribution to journal › Comment/debate
Open Access -
IRX2 and NPTX1 differential regulation of β-catenin underlies MEK-mediated proliferation in human neuroglial cells
Chen, A., Wang, H., Li, X., Anastasaki, C. & Gutmann, D. H., Jun 1 2025, In: Genes and Development. 39, 11-12, p. 697-705 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations