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Personal profile

Research interests

My focus is on developing and applying computational tools to provide insight into the origins and progression of cancer. This includes understanding the clonal architecture of tumors and how they evolve in response to therapy, with a special focus on hematologic cancers. I also study effective design and targeting of cancer immunotherapies, developing open-source software for interpreting and visualizing genomic data, and integrative analysis that translates multi-dimensional genomic data into both functional and actionable contexts.

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Research Output

  • 31170 Citations
  • 113 Article
  • 7 Comment/debate
  • 5 Letter
  • 1 Review article

HPV-EM: an accurate HPV detection and genotyping EM algorithm

Inkman, M. J., Jayachandran, K., Ellis, T. M., Ruiz, F., McLellan, M. D., Miller, C. A., Wu, Y., Ojesina, A. I., Schwarz, J. K. & Zhang, J., Dec 1 2020, In : Scientific reports. 10, 1, 14340.

Research output: Contribution to journalArticle

Open Access
  • Interleukin-15 superagonist (N-803) treatment of PML and JCV in a post-allogeneic hematopoietic stem cell transplant patient

    Oza, A., Rettig, M. P., Powell, P., O'Brien, K., Clifford, D. B., Ritchey, J., Gehrs, L., Hollaway, J., Major, E., Fehniger, T. A., Miller, C. A., Soon-Shiong, P., Rock, A. & DiPersio, J. F., Jun 9 2020, In : Blood Advances. 4, 11, p. 2387-2391 5 p.

    Research output: Contribution to journalArticle

    Open Access
    1 Scopus citations

    Pan-cancer analysis of whole genomes

    The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In : Nature. 578, 7793, p. 82-93 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 125 Scopus citations

    PVACtools: A computational toolkit to identify and visualize cancer neoantigens

    Hundal, J., Kiwala, S., McMichael, J., Miller, C. A., Xia, H., Wollam, A. T., Liu, C. J., Zhao, S., Feng, Y. Y., Graubert, A. P., Wollam, A. Z., Neichin, J., Neveau, M., Walker, J., Gillanders, W. E., Mardis, E. R., Griffith, O. L. & Griffith, M., Mar 1 2020, In : Cancer immunology research. 8, 3, p. 409-420 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations

    Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

    Ketkar, S., Verdoni, A. M., Smith, A. M., Bangert, C. V., Leight, E. R., Chen, D. Y., Brune, M. K., Helton, N. M., Hoock, M., George, D. R., Fronick, C., Fulton, R. S., Ramakrishnan, S. M., Chang, G. S., Petti, A. A., Spencer, D. H., Miller, C. A. & Ley, T. J., Feb 11 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 6, p. 3123-3134 12 p.

    Research output: Contribution to journalArticle

    Open Access