Chris Nelson

Research output

Research output per year 1987 1989 1990 1996 2006 2012 2014 2016 2018 2019 2020 2021 2021

• 6192 Citations
• 69 Article
• 5 Review article

Research output per year

Research output per year

Search results

• 1997

  Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules

  Nelson, C. A., Vidavsky, I., Viner, N. J., Gross, M. L. & Unanue, E. R., Jan 21 1997, In: Proceedings of the National Academy of Sciences of the United States of America. 94, 2, p. 628-633 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hen egg lysozyme 100%
  • Major Histocompatibility Complex 82%
  • Peptides 51%
  • Antigen Presentation 35%
  • Exopeptidases 26%
  71 Scopus citations

• Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody

  Dadaglio, G., Nelson, C. A., Deck, M. B., Petzold, S. J. & Unanue, E. R., Jun 1997, In: Immunity. 6, 6, p. 727-738 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hen egg lysozyme 100%
  • hen egg lysozyme (48-62) 77%
  • Monoclonal Antibodies 47%
  • Peptides 41%
  • Epitope Mapping 22%
  140 Scopus citations
• 1996

  Amino acid residues on the I-A^k α-chain required for the binding and stability of two antigenic peptides

  Nelson, C. A., Viner, N., Young, S., Petzold, S., Benoist, C., Mathis, D. & Unanue, E. R., Jan 1 1996, In: Journal of Immunology. 156, 1, p. 176-182 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acids 100%
  • Peptides 90%
  • hen egg lysozyme (48-62) 38%
  • hen egg lysozyme 24%
  • Peptide Fragments 21%
  23 Scopus citations

• A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-A(k)

  Nelson, C. A., Viner, N. J., Young, S. P., Petzold, S. J. & Unanue, E. R., Jul 15 1996, In: Journal of Immunology. 157, 2, p. 755-762 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Histocompatibility Antigens Class II 100%
  • Peptides 57%
  • polyalanine 16%
  • Amino Acids 14%
  • polyacrylamide gels 12%
  73 Scopus citations

• Appreciating the complexity of MHC class II peptide binding: Lysozyme peptide and I-A(k)

  Nelson, C. A., Viner, N. J. & Unanue, E. R., Jan 1 1996, In: Immunological Reviews. 151, p. 81-105 25 p.

  Research output: Contribution to journal › Review article › peer-review

  43 Scopus citations

• Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing

  Viner, N. J., Nelson, C. A., Deck, B. & Unanue, E. R., Apr 1 1996, In: Journal of Immunology. 156, 7, p. 2365-2368 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Histocompatibility Antigens Class II 100%
  • hen egg lysozyme 70%
  • Peptides 57%
  • Hybridomas 38%
  • T-Cell Antigen Receptor Specificity 16%
  119 Scopus citations

• TCR-Mediated Adhesion of T Cell Hybridomas to Planar Bilayers Containing Purified MHC Class II/Peptide Complexes and Receptor Shedding during Detachment

  Dustin, M. L., Miller, J. M., Ranganath, S., Vignali, D. A. A., Viner, N. J., Nelson, C. A. & Unanue, E. R., Sep 1 1996, In: Journal of Immunology. 157, 5, p. 2014-2021 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Receptors 100%
  • Hybridomas 90%
  • Histocompatibility Antigens Class II 87%
  • T-Lymphocytes 49%
  • Intercellular Adhesion Molecule-1 41%
  43 Scopus citations
• 1995

  Identification of a major I-E^k-restricted determinant of hen egg lysozyme: Limitations of lymph node proliferation studies in defining immunodominance and crypticity

  Viner, N. J., Nelson, C. A. & Unanue, E. R., Mar 14 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 6, p. 2214-2218 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hen egg lysozyme 100%
  • Lymph Nodes 46%
  • Immunization 30%
  • Hybridomas 24%
  • Peptides 13%
  64 Scopus citations
• 1994

  Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell

  Nelson, C. A., Petzold, S. J. & Unanue, E. R., 1994, In: Nature. 371, 6494, p. 250-252 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Antigen-Presenting Cells 100%
  • Major Histocompatibility Complex 97%
  • Longevity 85%
  • hen egg lysozyme 73%
  • Egg White 68%
  164 Scopus citations
• 1993

  Identification of two distinct properties of class II major histocompatibility complex-associated peptides

  Nelson, C. A., Petzold, S. J. & Unanue, E. R., Feb 15 1993, In: Proceedings of the National Academy of Sciences of the United States of America. 90, 4, p. 1227-1231 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Major Histocompatibility Complex 100%
  • Peptides 62%
  • hen egg lysozyme 50%
  • Egg White 35%
  • Antigen-Presenting Cells 17%
  108 Scopus citations
• 1992

  Biochemical anatomy of antigen processing

  Nelson, C. A., Harding, C. V. & Unanue, E. R., Dec 1 1992, In: Cold Spring Harbor symposia on quantitative biology. 57, p. 557-564 8 p.

  Research output: Contribution to journal › Article › peer-review

  5 Scopus citations

• Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-A^k

  Nelson, C. A., Roof, R. W., McCourt, D. W. & Unanue, E. R., 1992, In: Proceedings of the National Academy of Sciences of the United States of America. 89, 16, p. 7380-7383 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hen egg lysozyme 100%
  • Egg White 92%
  • Major Histocompatibility Complex 66%
  • Peptides 20%
  • Epitopes 18%
  170 Scopus citations
• 1990

  Evidence for CD8-independent T cell maturation in transgenic mice

  Russell, J. H., Meleedy-Rey, P., McCulley, D. E., Sha, W. C., Nelson, C. A. & Loh, D. Y., 1990, In: Journal of Immunology. 144, 9, p. 3318-3325 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Haplotypes 100%
  • Transgenic Mice 95%
  • T-Lymphocytes 65%
  • Phenotype 21%
  • Cell Line 20%
  55 Scopus citations

• Functional analysis of the murine T-cell receptor β enhancer and characteristics of its DNA-binding proteins

  Takeda, J., Cheng, A., Mauxion, F., Nelson, C. A., Newberry, R. D., Sha, W. C., Sen, R. & Loh, D. Y., 1990, In: Molecular and cellular biology. 10, 10, p. 5027-5035 9 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA-Binding Proteins 100%
  • T-Cell Antigen Receptor 90%
  • Phorbol 12,13-Dibutyrate 42%
  • T-Lymphocytes 36%
  • Deoxyribonuclease I 35%
  52 Scopus citations

• Genetic linkage map of 46 DNA markers on human chromosome 16

  Keith, T. P., Green, P., Reeders, S. T., Brown, V. A., Phipps, P., Bricker, A., Falls, K., Rediker, K. S., Powers, J. A., Hogan, C., Nelson, C., Knowlton, R. & Donis-Keller, H., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 15, p. 5754-5758 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chromosomes, Human, Pair 16 100%
  • Genetic Linkage 95%
  • Human Chromosomes 83%
  • Genetic Markers 76%
  • Genetic Recombination 46%
  28 Scopus citations

• Positive selection of transgenic receptor-bearing thymocytes by K^b antigen is altered by K^b mutations that involve peptide binding

  Sha, W. C., Nelson, C. A., Newberry, R. D., Pullen, J. K., Pease, L. R., Russell, J. H. & Loh, D. Y., Aug 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 16, p. 6186-6190 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Thymocytes 100%
  • Peptides 58%
  • Antigens 58%
  • Mutation 51%
  • Major Histocompatibility Complex 40%
  163 Scopus citations

• The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity

  Holloway, J. M., Glass, C. K., Adler, S., Nelson, C. A. & Rosenfeld, M. G., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 20, p. 8160-8164 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Thyroid Hormone Receptors 100%
  • Response Elements 66%
  • Estrogen Receptors 42%
  • DNA 42%
  • Estrogens 37%
  44 Scopus citations
• 1989

  An extremely polymorphic locus on the short arm of the human X chromosome with homology to the long arm of the Y chromosome

  Knowlton, R. G., Nelson, C. A., Brown, V. A., Page, D. C. & Donis-Keller, H., Jan 11 1989, In: Nucleic acids research. 17, 1, p. 423-437 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Chromosomes, Human, X 100%
  • Y Chromosome 78%
  • X Chromosome 72%
  • Haplotypes 60%
  • Meiosis 29%
  48 Scopus citations

• Identification and characterization of new murine T cell receptor β chain variable region (V_β) genes

  Louie, M. C., Nelson, C. A. & Loh, D. Y., Dec 1 1989, In: Journal of Experimental Medicine. 170, 6, p. 1987-1998 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  34 Scopus citations

• Positive and negative selection of T lymphocytes

  Loh, D. Y., Sha, W. C., Nelson, C. A., Newberry, R. D., Kranz, D. M. & Russell, J. H., Dec 1 1989, In: Cold Spring Harbor symposia on quantitative biology. 54, 1, p. 147-151 5 p.

  Research output: Contribution to journal › Article › peer-review

  7 Scopus citations
• 1988

  Positive and negative selection of an antigen receptor on T cells in transgenic mice

  Sha, W. C., Nelson, C. A., Newberry, R. D., Kranz, D. M., Russell, J. H. & Loh, D. Y., 1988, In: Nature. 336, 6194, p. 73-76 4 p.

  Research output: Contribution to journal › Article › peer-review

  • T-Cell Antigen Receptor 100%
  • Transgenic Mice 87%
  • T-Lymphocytes 60%
  • Major Histocompatibility Complex 40%
  • T-Cell Antigen Receptor Specificity 14%
  703 Scopus citations

• Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

  Sha, W. C., Nelson, C. A., Newberry, R. D., Kranzt, D. M., Russell, J. H. & Loh, D. Y., 1988, In: Nature. 335, 6187, p. 271-274 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Antigen Receptors 100%
  • T-Cell Antigen Receptor Specificity 76%
  • Transgenic Mice 71%
  • Clone Cells 63%
  • T-Lymphocytes 49%
  442 Scopus citations
• 1987

  Genetic linkage map of human chromosome 7 with 63 DNA markers

  Barker, D., Green, P., Knowlton, R., Schumm, J., Lander, E., Oliphant, A., Willard, H., Akots, G., Brown, V., Gravius, T., Helms, C., Nelson, C., Parker, C., Rediker, K., Rising, M., Watt, D., Weiffenbach, B. & Donis-Keller, H., 1987, In: Proceedings of the National Academy of Sciences of the United States of America. 84, 22, p. 8006-8010 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Linkage 100%
  • Chromosomes, Human, Pair 7 98%
  • Human Chromosomes 87%
  • Genetic Markers 80%
  • Chromosomes, Human, Pair 20 56%
  66 Scopus citations

• Germline organization of the murine T cell receptor β-chain genes

  Chou, H. S., Nelson, C. A., Godambe, S. A., Chaplin, D. D. & Loh, D. Y., 1987, In: Science. 238, 4826, p. 545-548 4 p.

  Research output: Contribution to journal › Article › peer-review

  • T-Cell Receptor Genes 100%
  • Genes 30%
  • Pulsed Field Gel Electrophoresis 17%
  • Gene Rearrangement 17%
  • DNA 8%
  42 Scopus citations