Chris Nelson

2001

Structural and functional consequences of altering a peptide MHC anchor residue

Kersh, G. J., Miley, M. J., Nelson, C. A., Grakoui, A., Horvath, S., Donermeyer, D. L., Kappler, J., Allen, P. M. & Fremont, D. H., Mar 1 2001, In: Journal of Immunology. 166, 5, p. 3345-3354 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

97 Scopus citations

2000

Hb(64-76) epitope binds in different registers and lengths to I-Eκ and I-Aκ

Vidal, K., Daniel, C., Vidavsky, I., Nelson, C. A. & Allen, P. M., Aug 15 2000, In: Molecular Immunology. 37, 5, p. 203-212 10 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice

Latek, R. R., Suri, A., Petzold, S. J., Nelson, C. A., Kanagawa, O., Unanue, E. R. & Fremont, D. H., 2000, In: Immunity. 12, 6, p. 699-710 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

171 Scopus citations

1999

Structural principles of MHC class II antigen presentation.

Nelson, C. A. & Fremont, D. H., 1999, In: Reviews in immunogenetics. 1, 1, p. 47-59 13 p.

Research output: Contribution to journal › Review article › peer-review

39 Scopus citations

1998

Crystal structure of I-A(k) in complex with a dominant epitope of lysozyme

Fremont, D. H., Monnaie, D., Nelson, C. A., Hendrickson, W. A. & Unanue, E. R., Mar 1998, In: Immunity. 8, 3, p. 305-317 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

224 Scopus citations

Isolation and quantitation of a minor determinant of hen egg white lysozyme bound to I-A(k) by using peptide-specific immunoaflinity

Gugasyan, R., Vidavsky, I., Nelson, C. A., Gross, M. L. & Unanue, E. R., Dec 1 1998, In: Journal of Immunology. 161, 11, p. 6074-6083 10 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

1997

Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules

Nelson, C. A., Vidavsky, I., Viner, N. J., Gross, M. L. & Unanue, E. R., Jan 21 1997, In: Proceedings of the National Academy of Sciences of the United States of America. 94, 2, p. 628-633 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

72 Scopus citations

Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody

Dadaglio, G., Nelson, C. A., Deck, M. B., Petzold, S. J. & Unanue, E. R., Jun 1997, In: Immunity. 6, 6, p. 727-738 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

145 Scopus citations

1996

Amino acid residues on the I-A^k α-chain required for the binding and stability of two antigenic peptides

Nelson, C. A., Viner, N., Young, S., Petzold, S., Benoist, C., Mathis, D. & Unanue, E. R., Jan 1 1996, In: Journal of Immunology. 156, 1, p. 176-182 7 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-A(k)

Nelson, C. A., Viner, N. J., Young, S. P., Petzold, S. J. & Unanue, E. R., Jul 15 1996, In: Journal of Immunology. 157, 2, p. 755-762 8 p.

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Appreciating the complexity of MHC class II peptide binding: Lysozyme peptide and I-A(k)

Nelson, C. A., Viner, N. J. & Unanue, E. R., 1996, In: Immunological Reviews. 151, p. 81-105 25 p.

Research output: Contribution to journal › Review article › peer-review

43 Scopus citations

Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing

Viner, N. J., Nelson, C. A., Deck, B. & Unanue, E. R., Apr 1 1996, In: Journal of Immunology. 156, 7, p. 2365-2368 4 p.

Research output: Contribution to journal › Article › peer-review

119 Scopus citations

TCR-Mediated Adhesion of T Cell Hybridomas to Planar Bilayers Containing Purified MHC Class II/Peptide Complexes and Receptor Shedding during Detachment

Dustin, M. L., Miller, J. M., Ranganath, S., Vignali, D. A. A., Viner, N. J., Nelson, C. A. & Unanue, E. R., Sep 1 1996, In: Journal of Immunology. 157, 5, p. 2014-2021 8 p.

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

1995

Identification of a major I-E^k-restricted determinant of hen egg lysozyme: Limitations of lymph node proliferation studies in defining immunodominance and crypticity

Viner, N. J., Nelson, C. A. & Unanue, E. R., Mar 14 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 6, p. 2214-2218 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

1994

Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell

Nelson, C. A., Petzold, S. J. & Unanue, E. R., 1994, In: Nature. 371, 6494, p. 250-252 3 p.

Research output: Contribution to journal › Article › peer-review

171 Scopus citations

1993

Identification of two distinct properties of class II major histocompatibility complex-associated peptides

Nelson, C. A., Petzold, S. J. & Unanue, E. R., Feb 15 1993, In: Proceedings of the National Academy of Sciences of the United States of America. 90, 4, p. 1227-1231 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

116 Scopus citations

1992

Biochemical anatomy of antigen processing

Nelson, C. A., Harding, C. V. & Unanue, E. R., 1992, In: Cold Spring Harbor symposia on quantitative biology. 57, p. 557-564 8 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-A^k

Nelson, C. A., Roof, R. W., McCourt, D. W. & Unanue, E. R., 1992, In: Proceedings of the National Academy of Sciences of the United States of America. 89, 16, p. 7380-7383 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

176 Scopus citations

1990

Evidence for CD8-independent T cell maturation in transgenic mice

Russell, J. H., Meleedy-Rey, P., McCulley, D. E., Sha, W. C., Nelson, C. A. & Loh, D. Y., May 1 1990, In: Journal of Immunology. 144, 9, p. 3318-3325 8 p.

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Functional analysis of the murine T-Cell receptor β enhancer and characteristics of its DNA-binding proteins

Takeda, J., Cheng, A., Mauxion, F., Nelson, C. A., Newberry, R. D., Sha, W. C., Sen, R. & Loh, D. Y., 1990, In: Molecular and cellular biology. 10, 10, p. 5027-5035 9 p.

Research output: Contribution to journal › Article › peer-review

74 Scopus citations

Genetic linkage map of 46 DNA markers on human chromosome 16

Keith, T. P., Green, P., Reeders, S. T., Brown, V. A., Phipps, P., Bricker, A., Falls, K., Rediker, K. S., Powers, J. A., Hogan, C., Nelson, C., Knowlton, R. & Donis-Keller, H., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 15, p. 5754-5758 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Positive selection of transgenic receptor-bearing thymocytes by K^b antigen is altered by K^b mutations that involve peptide binding

Sha, W. C., Nelson, C. A., Newberry, R. D., Pullen, J. K., Pease, L. R., Russell, J. H. & Loh, D. Y., Aug 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 16, p. 6186-6190 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

176 Scopus citations

The C′-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity

Holloway, J. M., Glass, C. K., Adler, S., Nelson, C. A. & Rosenfeld, M. G., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 20, p. 8160-8164 5 p.

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

1989

An extremely polymorphic locus on the short arm of the human X chromosome with homology to the long arm of the Y chromosome

Knowlton, R. G., Nelson, C. A., Brown, V. A., Page, D. C. & Donis-Keller, H., Jan 11 1989, In: Nucleic acids research. 17, 1, p. 423-437 15 p.

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Identification and characterization of new murine T cell receptor β chain variable region (V_β) genes

Louie, M. C., Nelson, C. A. & Loh, D. Y., Dec 1 1989, In: Journal of Experimental Medicine. 170, 6, p. 1987-1998 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

Positive and negative selection of T lymphocytes

Loh, D. Y., Sha, W. C., Nelson, C. A., Newberry, R. D., Kranz, D. M. & Russell, J. H., Dec 1 1989, In: Cold Spring Harbor symposia on quantitative biology. 54, 1, p. 147-151 5 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

1988

Positive and negative selection of an antigen receptor on T cells in transgenic mice

Sha, W. C., Nelson, C. A., Newberry, R. D., Kranz, D. M., Russell, J. H. & Loh, D. Y., 1988, In: Nature. 336, 6194, p. 73-76 4 p.

Research output: Contribution to journal › Article › peer-review

794 Scopus citations

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

Sha, W. C., Nelson, C. A., Newberry, R. D., Kranzt, D. M., Russell, J. H. & Loh, D. Y., 1988, In: Nature. 335, 6187, p. 271-274 4 p.

Research output: Contribution to journal › Article › peer-review

481 Scopus citations

1987

Genetic linkage map of human chromosome 7 with 63 DNA markers

Barker, D., Green, P., Knowlton, R., Schumm, J., Lander, E., Oliphant, A., Willard, H., Akots, G., Brown, V., Gravius, T., Helms, C., Nelson, C., Parker, C., Rediker, K., Rising, M., Watt, D., Weiffenbach, B. & Donis-Keller, H., 1987, In: Proceedings of the National Academy of Sciences of the United States of America. 84, 22, p. 8006-8010 5 p.

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Germline organization of the murine T cell receptor β-chain genes

Chou, H. S., Nelson, C. A., Godambe, S. A., Chaplin, D. D. & Loh, D. Y., 1987, In: Science. 238, 4826, p. 545-548 4 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Chris Nelson

Research output

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