Research output per year
Research output per year
Personal profile
Research interests
My research interest is in understanding the pathophysiology of tauopathies, especially Alzheimer’s Disease (AD), through tau kinetics.
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Collaborations and top research areas from the last five years
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Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease
and the Dominantly Inherited Alzheimer Network, Horie, K., Li, Y., Barthelemy, N., Gordon, B., Hassenstab, J., Benzinger, T., Niven, A., Morris, J., Karch, C. M., Xiong, C., Allegri, R., Mendez, P. C., Ikeuchi, T., Kasuga, K., Noble, J., Farlow, M., Chhatwal, J., Day, G. & Schofield, P. R. & 11 others, , Jun 2023, In: Annals of neurology. 93, 6, p. 1158-1172 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease
Horie, K., Salvadó, G., Barthélemy, N. R., Janelidze, S., Li, Y., He, Y., Saef, B., Chen, C. D., Jiang, H., Strandberg, O., Pichet Binette, A., Palmqvist, S., Sato, C., Sachdev, P., Koyama, A., Gordon, B. A., Benzinger, T. L. S., Holtzman, D. M., Morris, J. C. & Mattsson-Carlgren, N. & 5 others, , Aug 2023, In: Nature medicine. 29, 8, p. 1954-1963 10 p.Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease
Barthélemy, N. R., Saef, B., Li, Y., Gordon, B. A., He, Y., Horie, K., Stomrud, E., Salvadó, G., Janelidze, S., Sato, C., Ovod, V., Henson, R. L., Fagan, A. M., Benzinger, T. L. S., Xiong, C., Morris, J. C., Hansson, O., Bateman, R. J. & Schindler, S. E., Apr 2023, In: Nature Aging. 3, 4, p. 391-401 11 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Association of BDNF Val66Met with Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease
Lim, Y. Y., Maruff, P., Barthélemy, N. R., Goate, A., Hassenstab, J., Sato, C., Fagan, A. M., Benzinger, T. L. S., Xiong, C., Cruchaga, C., Levin, J., Farlow, M. R., Graff-Radford, N. R., Laske, C., Masters, C. L., Salloway, S., Schofield, P. R., Morris, J. C., Bateman, R. J. & McDade, E., Mar 2022, In: JAMA Neurology. 79, 3, p. 261-270 10 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction
Ezerskiy, L. A., Schoch, K. M., Sato, C., Beltcheva, M., Horie, K., Rigo, F., Martynowicz, R., Karch, C. M., Bateman, R. J. & Miller, T. M., Jan 11 2022, In: JCI Insight. 7, 1, 152012.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations