Keyphrases
3-dione Derivatives
19%
Activation Mechanism
24%
Autoinhibition
22%
Benzo
19%
Biophysical Characterization
19%
Caspase-1
22%
Caspase-8
38%
Catenin
19%
Combined Immunodeficiency
19%
Cryo-EM Structure
19%
Cryogenic Electron Microscopy
23%
Death Effector Domain
38%
Dimerization
29%
DNA Polymerase
19%
IL-1 Receptor-associated Kinase 1 (IRAK1)
19%
Immune Signaling
21%
Independent Functions
19%
Induced Activation
19%
Inflammasome
66%
Inflammasome Activation
32%
Inflammasome Assembly
21%
Inhibitory Pathways
19%
Isoindole-1,3-dione
19%
Kinase Domain
31%
Mechanism Elucidation
19%
Mechanosensitive Ion Channels
19%
Molecular Mechanism
22%
Mouse Model
19%
NLRP6
54%
NLRP6 Inflammasome
38%
Novel Therapeutic Targets
19%
Phase Separation
38%
POLD1
19%
Polo-box Domain
19%
Polo-like Kinase 1 (PLK1)
19%
Protein Function
19%
PSMD4
19%
PTEN Tumor Suppressor
19%
Pyrin Domain
29%
RNA Virus
21%
Structural Elucidation
19%
Structure Control
19%
Structure-based Design
19%
Supramolecular Complex
21%
Thermomonospora Curvata
19%
TMEM175
19%
TMEM63
19%
TNF Receptor Associated Factor 6
19%
Ubiquitin
19%
WWP1
19%
Biochemistry, Genetics and Molecular Biology
Autoinhibition
22%
Binding Domain
10%
C-Terminus
14%
Cancer Cell
19%
CARD Domain
19%
Caspase 1
22%
Caspase 8
38%
Cell Proliferation
12%
Computer Simulation
14%
Cryoelectron Microscopy
27%
Crystal Structure
57%
Death Effector Domain
38%
Dimerization
30%
DNA Polymerase Delta
19%
Drive
23%
Immunity
24%
Inflammasome
67%
Ion Channel
14%
IRAK1
19%
IRAK4
12%
Kinase
34%
Leucine-Rich Repeat
10%
Loss of Function Mutation
19%
Mechanosensitive Ion Channel
19%
Mouse Model
19%
Mutagenesis
11%
N-Terminus
11%
NLR Family Pyrin Domain containing 3
19%
NLRC4
19%
NLRP6
57%
Oligomerization
14%
Phase Separation
38%
Phosphotransferase
34%
Polo-Like Kinase 1
19%
Potassium Channel
19%
Potassium Conductance
19%
Programmed Cell Death
14%
Proteasome
19%
Protein Function
19%
Protein-Protein Interaction
19%
Proteome
19%
Pyrin Domain
26%
RNA Virus
21%
T Cell
19%
Thermomonospora
19%
TNF Receptor Associated Factor
19%
TRPM8
19%
Tumor Progression
14%
Ubiquitin
38%
WD40 Repeat
19%
Immunology and Microbiology
Adaptive Immune System
6%
B Cell
9%
Caspase 1
26%
Caspase Activation and Recruitment Domain
19%
CD4
6%
Cell Death
8%
Chemical Structure
6%
Combined Immunodeficiencies
19%
Cryo-Electron Microscopy
38%
Cytotoxic T-Cell
9%
Dispersion
6%
DNA Polymerase
19%
Enzyme Active Site
9%
Host-Pathogen Interaction
19%
Immunity
19%
Immunocompetent Cell
6%
Infectious Agent
9%
Inflammasome
100%
Innate Immune System
6%
interferon
5%
Intermolecular Interaction
6%
Leucine
19%
Loss of Function Mutation
19%
Mouse Model
19%
Mouse Mutant
5%
Multiple Myeloma
19%
Mutagenesis
6%
Myeloma Cell
7%
NLRC4
19%
NLRP6
38%
Phase Separation
38%
Proteasome
11%
Protein Protein Interaction
6%
Pyrin Domain
19%
RNA Virus
21%
T Cell
19%
Trans Golgi Network
6%
Ubiquitins
19%
