Research Output per year
Research Output per year
Personal profile
Research interests
My goal as a physician-scientist is to interface between medicine and basic science to confront challenging fundamental questions in cancer biology. In particular, I study the molecular regulation of cancer initiation in melanoma - the events that occur at the very start of tumor formation - during which cells readopt stem cell-like characteristics.
Areas of Clinical Interest
Cancer initiation, melanoma
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Research Output
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Difference in biophysical properties of cancer-initiating cells in melanoma mutated zebrafish
Makarova, N., Kalaparthi, V., Wang, A., Williams, C., Dokukin, M. E., Kaufman, C. K., Zon, L. & Sokolov, I., Jul 2020, In: Journal of the Mechanical Behavior of Biomedical Materials. 107, 103746.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates
Parker, H. J., De Kumar, B., Green, S. A., Prummel, K. D., Hess, C., Kaufman, C. K., Mosimann, C., Wiedemann, L. M., Bronner, M. E. & Krumlauf, R., Dec 1 2019, In: Nature communications. 10, 1, 1189.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Feeding amount significantly alters overt tumor onset rate in a zebrafish melanoma model
Grigura, V., Barbier, M., Zarov, A. P. & Kaufman, C. K., Jan 1 2018, In: Biology Open. 7, 1, 030726.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development
Ciarlo, C., Kaufman, C. K., Kinikoglu, B., Michael, J., Yang, S., D’Amato, C., Blokzijl-Franke, S., den Hertog, J., Schlaeger, T. M., Zhou, Y., Liao, E. & Zon, L. I., Aug 23 2017, In: eLife. 6, e29145.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors
Fazio, M., Avagyan, S., Van Rooijen, E., Mannherz, W., Kaufman, C. K., Lobbardi, R., Langenau, D. M. & Zon, L. I., Aug 2017, In: Zebrafish. 14, 4, p. 379-382 4 p.Research output: Contribution to journal › Article › peer-review