Research output per year
Research output per year
Personal profile
Research interests
My goal as a physician-scientist is to interface between medicine and basic science to confront challenging fundamental questions in cancer biology. In particular, I study the molecular regulation of cancer initiation in melanoma - the events that occur at the very start of tumor formation - during which cells readopt stem cell-like characteristics.
Areas of Clinical Interest
Cancer initiation, melanoma
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Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish
Jang, H. S., Chen, Y., Ge, J., Wilkening, A. N., Hou, Y., Lee, H. J., Choi, Y. R., Lowdon, R. F., Xing, X., Li, D., Kaufman, C. K., Johnson, S. L. & Wang, T., Dec 2021, In: Genome biology. 22, 1, 282.Research output: Contribution to journal › Article › peer-review
Open Access -
Functional in vivo characterization of sox10 enhancers in neural crest and melanoma development
Cunningham, R. L., Kramer, E. T., DeGeorgia, S. K., Godoy, P. M., Zarov, A. P., Seneviratne, S., Grigura, V. & Kaufman, C. K., Dec 2021, In: Communications Biology. 4, 1, 695.Research output: Contribution to journal › Article › peer-review
Open Access -
Isotope tracing in adult zebrafish reveals alanine cycling between melanoma and liver
Naser, F. J., Jackstadt, M. M., Fowle-Grider, R., Spalding, J. L., Cho, K., Stancliffe, E., Doonan, S. R., Kramer, E. T., Yao, L., Krasnick, B., Ding, L., Fields, R. C., Kaufman, C. K., Shriver, L. P., Johnson, S. L. & Patti, G. J., Jul 6 2021, In: Cell metabolism. 33, 7, p. 1493-1504.e5Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Melanoma models for the next generation of therapies
Patton, E. E., Mueller, K. L., Adams, D. J., Anandasabapathy, N., Aplin, A. E., Bertolotto, C., Bosenberg, M., Ceol, C. J., Burd, C. E., Chi, P., Herlyn, M., Holmen, S. L., Karreth, F. A., Kaufman, C. K., Khan, S., Kobold, S., Leucci, E., Levy, C., Lombard, D. B., Lund, A. W. & 16 others, , May 10 2021, In: Cancer Cell. 39, 5, p. 610-631 22 p.Research output: Contribution to journal › Review article › peer-review
7 Scopus citations -
Satb2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance
Fazio, M., van Rooijen, E., Dang, M., van de Hoek, G., Ablain, J., Mito, J. K., Yang, S., Thomas, A., Michael, J., Fabo, T., Modhurima, R., Pessina, P., Kaufman, C. K., Zhou, Y., White, R. M. & Zon, L. I., Feb 2021, In: eLife. 10, p. 1-28 28 p., e64370.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations