• 1281 Citations

Research output per year

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Personal profile

Research interests

My goal as a physician-scientist is to interface between medicine and basic science to confront challenging fundamental questions in cancer biology. In particular, I study the molecular regulation of cancer initiation in melanoma - the events that occur at the very start of tumor formation - during which cells readopt stem cell-like characteristics.

Areas of Clinical Interest

Cancer initiation, melanoma

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Research Output

  • 1281 Citations
  • 18 Article
  • 1 Chapter
  • 1 Short survey

Difference in biophysical properties of cancer-initiating cells in melanoma mutated zebrafish

Makarova, N., Kalaparthi, V., Wang, A., Williams, C., Dokukin, M. E., Kaufman, C. K., Zon, L. & Sokolov, I., Jul 2020, In : Journal of the Mechanical Behavior of Biomedical Materials. 107, 103746.

Research output: Contribution to journalArticle

  • A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates

    Parker, H. J., De Kumar, B., Green, S. A., Prummel, K. D., Hess, C., Kaufman, C. K., Mosimann, C., Wiedemann, L. M., Bronner, M. E. & Krumlauf, R., Dec 1 2019, In : Nature communications. 10, 1, 1189.

    Research output: Contribution to journalArticle

    Open Access
  • 10 Scopus citations

    Feeding amount significantly alters overt tumor onset rate in a zebrafish melanoma model

    Grigura, V., Barbier, M., Zarov, A. P. & Kaufman, C. K., Jan 1 2018, In : Biology Open. 7, 1, 030726.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development

    Ciarlo, C., Kaufman, C. K., Kinikoglu, B., Michael, J., Yang, S., D’Amato, C., Blokzijl-Franke, S., den Hertog, J., Schlaeger, T. M., Zhou, Y., Liao, E. & Zon, L. I., Aug 23 2017, In : eLife. 6, e29145.

    Research output: Contribution to journalArticle

  • 9 Scopus citations

    Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors

    Fazio, M., Avagyan, S., Van Rooijen, E., Mannherz, W., Kaufman, C. K., Lobbardi, R., Langenau, D. M. & Zon, L. I., Aug 2017, In : Zebrafish. 14, 4, p. 379-382 4 p.

    Research output: Contribution to journalArticle