Charles Gu

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Charles Gu

Associate Professor of Biostatistics, Associate Professor of Genetics

 https://orcid.org/0000-0002-8527-8145

    Willing to Mentor

    Available to Mentor:

    PhD/MSTP Students

    • 6521
      Citations
    1993 …2024

    Research activity per year

    Search results

    • Article

      Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI

      Gong, J., Nishimura, K. K., Fernandez-Rhodes, L., Haessler, J., Bien, S., Graff, M., Lim, U., Lu, Y., Gross, M., Fornage, M., Yoneyama, S., Isasi, C. R., Buzkova, P., Daviglus, M., Lin, D. Y., Tao, R., Goodloe, R., Bush, W. S., Farber-Eger, E. & Boston, J. & 28 others, Dilks, H. H., Ehret, G., Gu, C. C., Lewis, C. E., Nguyen, K. D. H., Cooper, R., Leppert, M., Irvin, M. R., Bottinger, E. P., Wilkens, L. R., Haiman, C. A., Park, L., Monroe, K. R., Cheng, I., Stram, D. O., Carlson, C. S., Jackson, R., Kuller, L., Houston, D., Kooperberg, C., Buyske, S., Hindorff, L. A., Crawford, D. C., Loos, R. J. F., Le Marchand, L., Matise, T. C., North, K. E. & Peters, U., Mar 1 2018, In: International Journal of Obesity. 42, 3, p. 384-390 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      10 Scopus citations

    • Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci

      Fernández-Rhodes, L., Gong, J., Haessler, J., Franceschini, N., Graff, M., Nishimura, K. K., Wang, Y., Highland, H. M., Yoneyama, S., Bush, W. S., Goodloe, R., Ritchie, M. D., Crawford, D., Gross, M., Fornage, M., Buzkova, P., Tao, R., Isasi, C., Avilés-Santa, L. & Daviglus, M. & 46 others, Mackey, R. H., Houston, D., Gu, C. C., Ehret, G., Nguyen, K. D. H., Lewis, C. E., Leppert, M., Irvin, M. R., Lim, U., Haiman, C. A., Le Marchand, L., Schumacher, F., Wilkens, L., Lu, Y., Bottinger, E. P., Loos, R. J. L., Sheu, W. H. H., Guo, X., Lee, W. J., Hai, Y., Hung, Y. J., Absher, D., Wu, I. C., Taylor, K. D., Lee, I. T., Liu, Y., Wang, T. D., Quertermous, T., Juang, J. M. J., Rotter, J. I., Assimes, T., Hsiung, C. A., Chen, Y. D. I., Prentice, R., Kuller, L. H., Manson, J. A. E., Kooperberg, C., Smokowski, P., Robinson, W. R., Gordon-Larsen, P., Li, R., Hindorff, L., Buyske, S., Matise, T. C., Peters, U. & North, K. E., Jun 1 2017, In: Human genetics. 136, 6, p. 771-800 30 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      29 Scopus citations

    • Variable set enrichment analysis in genome-wide association studies

      Yang, W., De Las Fuentes, L., Dávila-Román, V. G. & Gu, C. C., Aug 2011, In: European Journal of Human Genetics. 19, 8, p. 893-900 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      12 Scopus citations

    • Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

      NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 1 2021, In: Nature communications. 12, 1, 3506.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      6 Scopus citations

    • Variation in genes that regulate blood pressure are associated with glomerular filtration rate in Chinese

      Montasser, M. E., Shimmin, L. C., Gu, D., Chen, J., Gu, C., Kelly, T. N., Jaquish, C. E., Rice, T. K., Rao, D. C., Cao, J., Chen, J., Liu, D. P., Whelton, P. K., Hamm, L. L., He, J. & Hixson, J. E., Mar 21 2014, In: PloS one. 9, 3, e92468.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      12 Scopus citations

    • Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations

      North, K. E., Franceschini, N., Avery, C. L., Baird, L., Graff, M., Leppert, M., Chung, J. H., Zhang, J., Hanis, C., Boerwinkle, E., Volcik, K. A., Grove, M. L., Mosley, T. H., Gu, C., Heiss, G., Pankow, J. S., Couper, D. J., Ballantyne, C. M., Linda Kao, W. H. & Weder, A. B. & 5 others, Cooper, R. S., Ehret, G. B., O'Connor, A. A., Chakravarti, A. & Hunt, S. C., Dec 2010, In: Acta Diabetologica. 47, SUPPL. 1, p. S199-S207

      Research output: Contribution to journal › Article › peer-review

      Open Access
      5 Scopus citations

    • Whole-exome sequencing and an iPSC-derived cardiomyocyte model provides a powerful platform for gene discovery in left ventricular hypertrophy

      Zhi, D., lrvin, M. R., Gu, C. C., Stoddard, A. J., Lorier, R., Matter, A., Rao, D. C., Srinivasasainagendra, V., Tiwari, H. K., Turner, A., Broeckel, U. & Arnett, D. K., 2012, In: Frontiers in Genetics. 3, MAY, Article 92.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      19 Scopus citations

    • Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify MYRIP, TRAPPC11, and SLC27A6 of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population

      Irvin, M. R., Aggarwal, P., Claas, S. A., de las Fuentes, L., Do, A. N., Gu, C. C., Matter, A., Olson, B. S., Patki, A., Schwander, K., Smith, J. D., Srinivasasainagendra, V., Tiwari, H. K., Turner, A. J., Nickerson, D. A., Rao, D. C., Broeckel, U. & Arnett, D. K., Feb 19 2021, In: Frontiers in Genetics. 12, 588452.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      6 Scopus citations

    • Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

      TOPMed Sleep Working Group & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 2021, In: Genome medicine. 13, 1, 136.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      19 Scopus citations

    • Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

      Tahir, U. A., Katz, D. H., Avila-Pachecho, J., Bick, A. G., Pampana, A., Robbins, J. M., Yu, Z., Chen, Z. Z., Benson, M. D., Cruz, D. E., Ngo, D., Deng, S., Shi, X., Zheng, S., Eisman, A. S., Farrell, L., Hall, M. E., Correa, A., Tracy, R. P. & Durda, P. & 410 others, Taylor, K. D., Liu, Y., Johnson, W. C., Guo, X., Yao, J., Chen, Y. D. I., Manichaikul, A. W., Ruberg, F. L., Blaner, W. S., Jain, D., Bouchard, C., Sarzynski, M. A., Rich, S. S., Rotter, J. I., Wang, T. J., Wilson, J. G., Clish, C. B., Natarajan, P., Gerszten, R. E., Abe, N., Abecasis, G., Aguet, F., Albert, C., Almasy, L., Alonso, A., Ament, S., Anderson, P., Anugu, P., Applebaum-Bowden, D., Ardlie, K., Arking, D., Arnett, D. K., Ashley-Koch, A., Aslibekyan, S., Assimes, T., Auer, P., Avramopoulos, D., Ayas, N., Balasubramanian, A., Barnard, J., Barnes, K., Barr, R. G., Barron-Casella, E., Barwick, L., Beaty, T., Beck, G., Becker, D., Becker, L., Beer, R., Beitelshees, A., Benjamin, E., Benos, T., Bezerra, M., Bielak, L., Bis, J., Blackwell, T., Blangero, J., Blue, N., Boerwinkle, E., Bowden, D. W., Bowler, R., Brody, J., Broeckel, U., Broome, J., Brown, D., Bunting, K., Burchard, E., Bustamante, C., Buth, E., Cade, B., Cardwell, J., Carey, V., Carrier, J., Carson, A., Carty, C., Casaburi, R., Romero, J. P. C., Casella, J., Castaldi, P., Chaffin, M., Chang, C., Chang, Y. C., Chasman, D., Chavan, S., Chen, B. J., Chen, W. M., Cho, M., Choi, S. H., Chuang, L. M., Chung, M., Chung, R. H., Comhair, S., Conomos, M., Cornell, E., Crandall, C., Crapo, J., Cupples, L. A., Curran, J., Curtis, J., Custer, B., Damcott, C., Darbar, D., David, S., Davis, C., Daya, M., de Andrade, M., Fuentes, L. D. L., de Vries, P., DeBaun, M., Deka, R., DeMeo, D., Devine, S., Dinh, H., Doddapaneni, H., Duan, Q., Dugan-Perez, S., Duggirala, R., Dutcher, S. K., Eaton, C., Ekunwe, L., El Boueiz, A., Ellinor, P., Emery, L., Erzurum, S., Farber, C., Farek, J., Fingerlin, T., Flickinger, M., Fornage, M., Franceschini, N., Frazar, C., Fu, M., Fullerton, S. M., Fulton, L., Gabriel, S., Gan, W., Gao, S., Gao, Y., Gass, M., Geiger, H., Gelb, B., Geraci, M., Germer, S., Ghosh, A., Gibbs, R., Gignoux, C., Gladwin, M., Glahn, D., Gogarten, S., Gong, D. W., Goring, H., Graw, S., Gray, K. J., Grine, D., Gross, C., Gu, C. C., Guan, Y., Gupta, N., Haessler, J., Han, Y., Hanly, P., Harris, D., Hawley, N. L., He, J., Heavner, B., Heckbert, S., Hernandez, R., Herrington, D., Hersh, C., Hidalgo, B., Hixson, J., Hobbs, B., Hokanson, J., Hong, E., Hoth, K., Hsiung, C., Hu, J., Hung, Y. J., Huston, H., Hwu, C. M., Irvin, M. R., Jackson, R., Jaquish, C., Johnsen, J., Johnson, A., Johnston, R., Jones, K., Kang, H. M., Kaplan, R., Kardia, S., Kelly, S., Kenny, E., Kessler, M., Khan, A., Khan, Z., Kim, W., Kimoff, J., Kinney, G., Konkle, B., Kooperberg, C., Kramer, H., Lange, C., Lange, E., Lange, L., Laurie, C., Laurie, C., LeBoff, M., Lee, J., Lee, S., Lee, W. J., LeFaive, J., Levine, D., Levy, D., Lewis, J., Li, X., Li, Y., Lin, H., Lin, H., Lin, X., Liu, S., Liu, Y., Loos, R. J. F., Lubitz, S., Lunetta, K., Luo, J., Magalang, U., Mahaney, M., Make, B., Manning, A., Manson, J. A., Martin, L., Marton, M., Mathai, S., Mathias, R., May, S., McArdle, P., McDonald, M. L., McFarland, S., McGarvey, S., McGoldrick, D., McHugh, C., McNeil, B., Mei, H., Meigs, J., Menon, V., Mestroni, L., Metcalf, G., Meyers, D. A., Mignot, E., Mikulla, J., Min, N., Minear, M., Minster, R. L., Mitchell, B. D., Moll, M., Momin, Z., Montasser, M. E., Montgomery, C., Muzny, D., Mychaleckyj, J. C., Nadkarni, G., Naik, R., Naseri, T., Nekhai, S., Nelson, S. C., Neltner, B., Nessner, C., Nickerson, D., Nkechinyere, O., North, K., O’Connell, J., O’Connor, T., Ochs-Balcom, H., Okwuonu, G., Pack, A., Paik, D. T., Palmer, N., Pankow, J., Papanicolaou, G., Parker, C., Peloso, G., Peralta, J. M., Perez, M., Perry, J., Peters, U., Peyser, P., Phillips, L. S., Pleiness, J., Pollin, T., Post, W., Becker, J. P., Boorgula, M. P., Preuss, M., Psaty, B., Qasba, P., Qiao, D., Qin, Z., Rafaels, N., Raffield, L., Rajendran, M., Ramachandran, V. S., Rao, D. C., Rasmussen-Torvik, L., Ratan, A., Redline, S., Reed, R., Reeves, C., Regan, E., Reiner, A., Reupena, M. S., Rice, K., Robillard, R., Robine, N., Dan Roden, R., Roselli, C., Ruczinski, I., Runnels, A., Russell, P., Ruuska, S., Sabino, E. C., Saleheen, D., Salimi, S., Salvi, S., Salzberg, S., Sandow, K., Sankaran, V. G., Santibanez, J., Schwander, K., Schwartz, D., Sciurba, F., Seidman, C., Seidman, J., Sériès, F., Sheehan, V., Sherman, S. L., Shetty, A., Shetty, A., Sheu, W. H. H., Shoemaker, M. B., Silver, B., Silverman, E., Skomro, R., Smith, A. V., Smith, J., Smith, J., Smith, N., Smith, T., Smoller, S., Snively, B., Snyder, M., Sofer, T., Sotoodehnia, N., Stilp, A. M., Storm, G., Streeten, E., Su, J. L., Sung, Y. J., Sylvia, J., Szpiro, A., Taliun, D., Tang, H., Taub, M., Taylor, M., Taylor, S., Telen, M., Thornton, T. A., Threlkeld, M., Tinker, L., Tirschwell, D., Tishkoff, S., Tiwari, H., Tong, C., Tsai, M., Vaidya, D., Van Den Berg, D., VandeHaar, P., Vrieze, S., Walker, T., Wallace, R., Walts, A., Wang, F. F., Wang, H., Wang, J., Watson, K., Watt, J., Weeks, D. E., Weinstock, J., Weir, B., Weiss, S. T., Weng, L. C., Wessel, J., Willer, C., Williams, K., Williams, L. K., Wilson, C., Winterkorn, L., Wong, Q., Wu, J., Xu, H., Yanek, L., Yang, I., Yu, K., Zekavat, S. M., Zhang, Y., Zhao, S. X., Zhao, W., Zhu, X., Ziv, E., Zody, M. & Zoellner, S., Dec 2022, In: Nature communications. 13, 1, 4923.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      13 Scopus citations

    • Whole genome sequence analysis of blood lipid levels in >66,000 individuals

      NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 2022, In: Nature communications. 13, 1, 5995.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      22 Scopus citations

    • Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma

      National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 1 2019, In: CHEST. 156, 6, p. 1068-1079 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      6 Scopus citations