• 4309
    Citations
1993 …2022

Research activity per year

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Search results

  • 2016

    Genetic Susceptibility to Lipid Levels and Lipid Change over Time and Risk of Incident Hyperlipidemia in Chinese Populations

    Lu, X., Huang, J., Mo, Z., He, J., Wang, L., Yang, X., Tan, A., Chen, S., Chen, J., Charles Gu, C., Chen, J., Li, Y., Zhao, L., Li, H., Hao, Y., Li, J., Hixson, J. E., Li, Y., Cheng, M., Liu, X., & 18 othersCao, J., Liu, F., Huang, C., Shen, C., Shen, J., Yu, L., Xu, L., Mu, J., Wu, X., Ji, X., Guo, D., Zhou, Z., Yang, Z., Wang, R., Yang, J., Yan, W., Peng, X. & Gu, D., Feb 1 2016, In: Circulation: Cardiovascular Genetics. 9, 1, p. 37-44 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    40 Scopus citations
  • Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study

    Li, C., He, J., Chen, J., Zhao, J., Gu, D., Hixson, J. E., Rao, D. C., Jaquish, C. E., Gu, C. C., Chen, J., Huang, J., Chen, S. & Kelly, T. N., Aug 1 2016, In: Hypertension. 68, 2, p. 348-355 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    28 Scopus citations
  • 2017

    Associations between genetic variants of NADPH oxidase-related genes and blood pressure responses to dietary sodium intervention: The GenSalt study

    Han, X., Hu, Z., Chen, J., Huang, J., Huang, C., Liu, F., Gu, C., Yang, X., Hixson, J. E., Lu, X., Wang, L., Liu, D. P., He, J., Chen, S. & Gu, D., Apr 1 2017, In: American Journal of Hypertension. 30, 4, p. 427-434 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • Blood pressure genetic risk score predicts blood pressure responses to dietary sodium and potassium the GenSalt Study (Genetic epidemiology network of salt sensitivity)

    Nierenberg, J. L., Li, C., He, J., Gu, D., Chen, J., Lu, X., Li, J., Wu, X., Gu, C. C., Hixson, J. E., Rao, D. C. & Kelly, T. N., 2017, In: Hypertension. 70, 6, p. 1106-1112 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations

    Yoneyama, S., Yao, J., Guo, X., Fernandez-Rhodes, L., Lim, U., Boston, J., Buzková, P., Carlson, C. S., Cheng, I., Cochran, B., Cooper, R., Ehret, G., Fornage, M., Gong, J., Gross, M., Gu, C. C., Haessler, J., Haiman, C. A., Henderson, B., Hindorff, L. A., & 30 othersHouston, D., Irvin, M. R., Jackson, R., Kuller, L., Leppert, M., Lewis, C. E., Li, R., Le Marchand, L., Matise, T. C., Nguyen, K. D., Chakravarti, A., Pankow, J. S., Pankratz, N., Pooler, L., Ritchie, M. D., Bien, S. A., Wassel, C. L., Chen, Y. D., Taylor, K. D., Allison, M., Rotter, J. I., Schreiner, P. J., Schumacher, F., Wilkens, L., Boerwinkle, E., Kooperberg, C., Peters, U., Buyske, S., Graff, M. & North, K. E., Feb 1 2017, In: International Journal of Obesity. 41, 2, p. 324-331 8 p.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry

    Nandakumar, P., Lee, D., Richard, M. A., Tekola-Ayele, F., Tayo, B. O., Ware, E., Sung, Y. J., Salako, B., Ogunniyi, A., Gu, C. C., Grove, M. L., Fornage, M., Kardia, S., Rotimi, C., Cooper, R. S., Morrison, A. C., Ehret, G. & Chakravarti, A., Jul 1 2017, In: Journal of Hypertension. 35, 7, p. 1381-1389 9 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation

    Zhou, J., Sears, R. L., Xing, X., Zhang, B., Li, D., Rockweiler, N. B., Jang, H. S., Choudhary, M. N. K., Lee, H. J., Lowdon, R. F., Arand, J., Tabers, B., Gu, C. C., Cicero, T. J. & Wang, T., Sep 12 2017, In: BMC genomics. 18, 1, 724.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    35 Scopus citations
  • Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci

    Fernández-Rhodes, L., Gong, J., Haessler, J., Franceschini, N., Graff, M., Nishimura, K. K., Wang, Y., Highland, H. M., Yoneyama, S., Bush, W. S., Goodloe, R., Ritchie, M. D., Crawford, D., Gross, M., Fornage, M., Buzkova, P., Tao, R., Isasi, C., Avilés-Santa, L., Daviglus, M., & 46 othersMackey, R. H., Houston, D., Gu, C. C., Ehret, G., Nguyen, K. D. H., Lewis, C. E., Leppert, M., Irvin, M. R., Lim, U., Haiman, C. A., Le Marchand, L., Schumacher, F., Wilkens, L., Lu, Y., Bottinger, E. P., Loos, R. J. L., Sheu, W. H. H., Guo, X., Lee, W. J., Hai, Y., Hung, Y. J., Absher, D., Wu, I. C., Taylor, K. D., Lee, I. T., Liu, Y., Wang, T. D., Quertermous, T., Juang, J. M. J., Rotter, J. I., Assimes, T., Hsiung, C. A., Chen, Y. D. I., Prentice, R., Kuller, L. H., Manson, J. A. E., Kooperberg, C., Smokowski, P., Robinson, W. R., Gordon-Larsen, P., Li, R., Hindorff, L., Buyske, S., Matise, T. C., Peters, U. & North, K. E., Jun 1 2017, In: Human genetics. 136, 6, p. 771-800 30 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • 2018

    A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

    The CHARGE Neurology Working Group, The COGENT-Kidney Consortium, The GIANT Consortium & Lifelines Cohort Study, Mar 1 2018, In: American journal of human genetics. 102, 3, p. 375-400 26 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    58 Scopus citations
  • Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

    NHLBI TOPMed Lipids Working Group, Dec 1 2018, In: Nature communications. 9, 1, 3391.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    83 Scopus citations
  • Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

    Zekavat, S. M., Ruotsalainen, S., Handsaker, R. E., Alver, M., Bloom, J., Poterba, T., Seed, C., Ernst, J., Chaffin, M., Engreitz, J., Peloso, G. M., Manichaikul, A., Yang, C., Ryan, K. A., Fu, M., Johnson, W. C., Tsai, M., Budoff, M., Ramachandran, V. S., Cupples, L. A., & 323 othersRotter, J. I., Rich, S. S., Post, W., Mitchell, B. D., Correa, A., Metspalu, A., Wilson, J. G., Salomaa, V., Kellis, M., Daly, M. J., Neale, B. M., McCarroll, S., Surakka, I., Esko, T., Ganna, A., Ripatti, S., Kathiresan, S., Natarajan, P., Abe, N., Abecasis, G., Albert, C., Allred, N. P., Almasy, L., Alonso, A., Ament, S., Anderson, P., Anugu, P., Applebaum-Bowden, D., Arking, D., Arnett, D. K., Ashley-Koch, A., Aslibekyan, S., Assimes, T., Auer, P., Avramopoulos, D., Barnard, J., Barnes, K., Barr, R. G., Barron-Casella, E., Beaty, T., Becker, D., Becker, L., Beer, R., Begum, F., Beitelshees, A., Benjamin, E., Bezerra, M., Bielak, L., Bis, J., Blackwell, T., Blangero, J., Boerwinkle, E., Borecki, I., Bowler, R., Brody, J., Broeckel, U., Broome, J., Bunting, K., Burchard, E., Cardwell, J., Carty, C., Casaburi, R., Casella, J., Chang, C., Chasman, D., Chavan, S., Chen, B. J., Chen, W. M., Chen, Y. D. I., Cho, M., Choi, S. H., Chuang, L. M., Chung, M., Cornell, E., Crandall, C., Crapo, J., Curran, J., Curtis, J., Custer, B., Damcott, C., Darbar, D., Das, S., David, S., Davis, C., Daya, M., Andrade, M. D., Debaun, M., Deka, R., Demeo, D., Devine, S., Do, R., Duan, Q., Duggirala, R., Durda, P., Dutcher, S., Eaton, C., Ekunwe, L., Ellinor, P., Emery, L., Farber, C., Farnam, L., Fingerlin, T., Flickinger, M., Fornage, M., Franceschini, N., Fullerton, S. M., Fulton, L., Gabriel, S., Gan, W., Gao, Y., Gass, M., Gelb, B., Geng, X., Germer, S., Gignoux, C., Gladwin, M., Glahn, D., Gogarten, S., Gong, D. W., Goring, H., Gu, C. C., Guan, Y., Guo, X., Haessler, J., Hall, M., Harris, D., Hawley, N., He, J., Heavner, B., Heckbert, S., Hernandez, R., Herrington, D., Hersh, C., Hidalgo, B., Hixson, J., Hokanson, J., Hong, E., Hoth, K., Hsiung, C., Huston, H., Hwu, C. M., Irvin, M. R., Jackson, R., Jain, D., Jaquish, C., Jhun, M. A., Johnsen, J., Johnson, A., Johnston, R., Jones, K., Kang, H. M., Kaplan, R., Kardia, S., Kaufman, L., Kelly, S., Kenny, E., Kessler, M., Khan, A., Kinney, G., Konkle, B., Kooperberg, C., Kramer, H., Krauter, S., Lange, C., Lange, E., Lange, L., Laurie, C., Laurie, C., Leboff, M., Lee, S. S., Lee, W. J., Lefaive, J., Levine, D., Levy, D., Lewis, J., Li, Y., Lin, H., Lin, K. H., Liu, S., Liu, Y., Loos, R., Lubitz, S., Lunetta, K., Luo, J., Mahaney, M., Make, B., Manson, J. A., Margolin, L., Martin, L., Mathai, S., Mathias, R., McArdle, P., McDonald, M. L., McFarland, S., McGarvey, S., Mei, H., Meyers, D. A., Mikulla, J., Min, N., Minear, M., Minster, R. L., Montasser, M. E., Musani, S., Mwasongwe, S., Mychaleckyj, J. C., Nadkarni, G., Naik, R., Nekhai, S., Nickerson, D., North, K., O'connell, J., O'connor, T., Ochs-Balcom, H., Pankow, J., Papanicolaou, G., Parker, M., Parsa, A., Penchev, S., Peralta, J. M., Perez, M., Perry, J., Peters, U., Peyser, P., Phillips, L., Phillips, S., Pollin, T., Becker, J. P., Boorgula, M. P., Preuss, M., Prokopenko, D., Psaty, B., Qasba, P., Qiao, D., Qin, Z., Rafaels, N., Raffield, L., Rao, D. C., Rasmussen-Torvik, L., Ratan, A., Redline, S., Reed, R., Regan, E., Reiner, A., Rice, K., Roden, D., Roselli, C., Ruczinski, I., Russell, P., Ruuska, S., Sakornsakolpat, P., Salimi, S., Salzberg, S., Sandow, K., Sankaran, V., Scheller, C., Schmidt, E., Schwander, K., Schwartz, D., Sciurba, F., Seidman, C., Sheehan, V., Shetty, A., Shetty, A., Sheu, W. H. H., Shoemaker, M. B., Silver, B., Silverman, E., Smith, J., Smith, J., Smith, N., Smith, T., Smoller, S., Snively, B., Sofer, T., Sotoodehnia, N., Stilp, A., Streeten, E., Sung, Y. J., Sylvia, J., Szpiro, A., Sztalryd, C., Taliun, D., Tang, H., Taub, M., Taylor, K., Taylor, S., Telen, M., Thornton, T. A., Tinker, L., Tirschwell, D., Tiwari, H., Tracy, R., Vaidya, D., Vandehaar, P., Vrieze, S., Walker, T., Wallace, R., Walts, A., Wan, E., Wang, F. F., Watson, K., Weeks, D. E., Weir, B., Weiss, S., Weng, L. C., Willer, C., Williams, K., Williams, L. K., Wilson, C., Wong, Q., Xu, H., Yanek, L., Yang, I., Yang, R., Zaghloul, N., Zhang, Y., Zhao, S. X., Zhao, W., Zheng, X., Zhi, D., Zhou, X., Zody, M. & Zoellner, S., Dec 1 2018, In: Nature communications. 9, 1, 2606.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    52 Scopus citations
  • Open Access
    1 Scopus citations
  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R., Aschard, H., & 252 othersBartz, T. M., Bielak, L. F., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Wojczynski, M. K., Alver, M., Boissel, M., Cai, Q., Campbell, A., Chai, J. F., Chen, X., Divers, J., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., He, M., Hsu, F. C., Jackson, A. U., Kähönen, M., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Luan, JA., Matoba, N., Nolte, I. M., Padmanabhan, S., Riaz, M., Rueedi, R., Robino, A., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Vitart, V., Wang, Y., Ware, E. B., Warren, H. R., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Boerwinkle, E., Borecki, I., Broeckel, U., Brown, M., Brumat, M., Burke, G. L., Canouil, M., Chakravarti, A., Charumathi, S., Chen, Y. D. I., Connell, J. M., Correa, A., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Deng, X., Ding, J., Duan, Q., Eaton, C. B., Ehret, G., Eppinga, R. N., Evangelou, E., Faul, J. D., Felix, S. B., Forouhi, N. G., Forrester, T., Franco, O. H., Friedlander, Y., Gandin, I., Gao, H., Ghanbari, M., Gigante, B., Gu, C. C., Gu, D., Hagenaars, S. P., Hallmans, G., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hirata, M., Howard, B. V., Ikram, M. A., John, U., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lewis, C. E., Li, Y., Lin, S., Liu, J., Liu, J., Loh, M., Louie, T., Mägi, R., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Momozawa, Y., Nalls, M. A., Nelson, C. P., Sotoodehnia, N., Norris, J. M., O'Connell, J. R., Palmer, N. D., Perls, T., Pedersen, N. L., Peters, A., Peyser, P. A., Poulter, N., Raffel, L. J., Raitakari, O. T., Roll, K., Rose, L. M., Rosendaal, F. R., Rotter, J. I., Schmidt, C. O., Schreiner, P. J., Schupf, N., Scott, W. R., Sever, P. S., Shi, Y., Sidney, S., Sims, M., Sitlani, C. M., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Stringham, H. M., Tan, N. Y. Q., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Turner, S. T., Uitterlinden, A. G., Vollenweider, P., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Williams, C., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Jonas, J. B., Kamatani, Y., Kato, N., Kooner, J. S., Kutalik, Z., Laakso, M., Laurie, C. C., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Oldehinkel, A. J., Penninx, B. W. J. H., Polasek, O., Porteous, D. J., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Wu, T., Zheng, W., Bouchard, C., Christensen, K., Evans, M. K., Gudnason, V., Horta, B. L., Kardia, S. L. R., Liu, Y., Pereira, A. C., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Gauderman, W. J., Zhu, X., Mook-Kanamori, D. O., Fornage, M., Rotimi, C. N., Cupples, L. A., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Kooperberg, C., Palmas, W., Rice, K., Morrison, A. C., Elliott, P., Caulfield, M. J., Munroe, P. B., Rao, D. C., Province, M. A. & Levy, D., Jun 2018, In: PloS one. 13, 6, e0198166.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    35 Scopus citations
  • Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI

    Gong, J., Nishimura, K. K., Fernandez-Rhodes, L., Haessler, J., Bien, S., Graff, M., Lim, U., Lu, Y., Gross, M., Fornage, M., Yoneyama, S., Isasi, C. R., Buzkova, P., Daviglus, M., Lin, D. Y., Tao, R., Goodloe, R., Bush, W. S., Farber-Eger, E., Boston, J., & 28 othersDilks, H. H., Ehret, G., Gu, C. C., Lewis, C. E., Nguyen, K. D. H., Cooper, R., Leppert, M., Irvin, M. R., Bottinger, E. P., Wilkens, L. R., Haiman, C. A., Park, L., Monroe, K. R., Cheng, I., Stram, D. O., Carlson, C. S., Jackson, R., Kuller, L., Houston, D., Kooperberg, C., Buyske, S., Hindorff, L. A., Crawford, D. C., Loos, R. J. F., Le Marchand, L., Matise, T. C., North, K. E. & Peters, U., Mar 1 2018, In: International Journal of Obesity. 42, 3, p. 384-390 7 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • 2019

    A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

    Sung, Y. J., De Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J., & 261 othersMusani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F. C., Jackson, A. U., Kammerer, C. M., Kasturiratne, A., Komulainen, P., Kühnel, B., Leander, K., Lee, W. J., Lin, K. H., Luan, J., Lyytikäinen, L. P., McKenzie, C. A., Nelson, C. P., Noordam, R., Scott, R. A., Sheu, W. H. H., Stančáková, A., Takeuchi, F., Van Der Most, P. J., Varga, T. V., Waken, R. J., Wang, H., Wang, Y., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Alfred, T., Amin, N., Arking, D. E., Aung, T., Barr, R. G., Bielak, L. F., Boerwinkle, E., Bottinger, E. P., Braund, P. S., Brody, J. A., Broeckel, U., Cade, B., Campbell, A., Canouil, M., Chakravarti, A., Cocca, M., Collins, F. S., Connell, J. M., De Mutsert, R., De Silva, H. J., Dörr, M., Duan, Q., Eaton, C. B., Ehret, G., Evangelou, E., Faul, J. D., Forouhi, N. G., Franco, O. H., Friedlander, Y., Gao, H., Gigante, B., Gu, C. C., Gupta, P., Hagenaars, S. P., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hofman, A., Howard, B. V., Hunt, S. C., Irvin, M. R., Jia, Y., Katsuya, T., Kaufman, J., Kerrison, N. D., Khor, C. C., Koh, W. P., Koistinen, H. A., Kooperberg, C. B., Krieger, J. E., Kubo, M., Kutalik, Z., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. H., Lehne, B., Levy, D., Lewis, C. E., Li, Y., Lim, S. H., Liu, C. T., Liu, J., Liu, J., Liu, Y., Loh, M., Lohman, K. K., Louie, T., Mägi, R., Matsuda, K., Meitinger, T., Metspalu, A., Milani, L., Momozawa, Y., Thomas, T. H., Nalls, M. A., Nasri, U., O'Connell, J. R., Ogunniyi, A., Palmas, W. R., Palmer, N. D., Pankow, J. S., Pedersen, N. L., Peters, A., Peyser, P. A., Polasek, O., Porteous, D., Raitakari, O. T., Renström, F., Rice, T. K., Ridker, P. M., Robino, A., Robinson, J. G., Rose, L. M., Rudan, I., Sabanayagam, C., Salako, B. L., Sandow, K., Schmidt, C. O., Schreiner, P. J., Scott, W. R., Sever, P., Sims, M., Sitlani, C. M., Smith, B. H., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Uitterlinden, A. G., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Wilson, G., Wojczynski, M. K., Xiang, Y. B., Yao, J., Yuan, J. M., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Chen, Y. D. I., Weir, D. R., De Faire, U., Deary, I. J., Esko, T., Farrall, M., Forrester, T., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Horta, B. L., Hung, Y. J., Jonas, J. B., Kato, N., Kooner, J. S., Laakso, M., Lehtimäki, T., Liang, K. W., Magnusson, P. K. E., Oldehinkel, A. J., Pereira, A. C., Perls, T., Rauramaa, R., Redline, S., Rettig, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Wickremasinghe, A. R., Wu, T., Kamatani, Y., Laurie, C. C., Bouchard, C., Cooper, R. S., Evans, M. K., Gudnason, V., Hixson, J., Kardia, S. L. R., Kritchevsky, S. B., Psaty, B. M., Van Dam, R. M., Arnett, D. K., Mook-Kanamori, D. O., Fornage, M., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Loos, R. J. F., Reiner, A. P., Rotimi, C. N., Bierut, L. J., Zhu, X., Cupples, L. A., Province, M. A., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., Aug 1 2019, In: Human molecular genetics. 28, 15, p. 2615-2633 19 p.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

    Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L., & 132 othersRichardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W. J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N. B., Lin, K. H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., Jan 3 2019, In: American journal of human genetics. 104, 1, p. 112-138 27 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    57 Scopus citations
  • Combined linkage and association analysis identifies rare and low frequency variants for blood pressure at 1q31

    Wang, H., Nandakumar, P., Tekola-Ayele, F., Tayo, B. O., Ware, E. B., Gu, C. C., Lu, Y., Yao, J., Zhao, W., Smith, J. A., Hellwege, J. N., Guo, X., Edwards, T. L., Loos, R. J. F., Arnett, D. K., Fornage, M., Rotimi, C., Kardia, S. L. R., Cooper, R. S., Rao, D. C., & 3 othersEhret, G., Chakravarti, A. & Zhu, X., Feb 1 2019, In: European Journal of Human Genetics. 27, 2, p. 269-277 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

    De Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A., Noordam, R., Aschard, H., & 246 othersBartz, T. M., Bielak, L. F., Deng, X., Dorajoo, R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Evangelou, E., Graff, M., Alver, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F. C., Jackson, A. U., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Lee, J. H., Luan, JA., Lyytikäinen, L. P., Matoba, N., Nolte, I. M., Pietzner, M., Riaz, M., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Wang, Y., Ware, E. B., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Ballantyne, C., Boerwinkle, E., Broeckel, U., Campbell, A., Canouil, M., Charumathi, S., Chen, Y. D. I., Connell, J. M., De Faire, U., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Ding, J., Dominiczak, A. F., Duan, Q., Eaton, C. B., Eppinga, R. N., Faul, J. D., Fisher, V., Forrester, T., Franco, O. H., Friedlander, Y., Ghanbari, M., Giulianini, F., Grabe, H. J., Grove, M. L., Gu, C. C., Harris, T. B., Heikkinen, S., Heng, C. K., Hirata, M., Hixson, J. E., Howard, B. V., Ikram, M. A., Jacobs, D. R., Johnson, C., Jonas, J. B., Kammerer, C. M., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Koistinen, H. A., Kolcic, I., Kooperberg, C., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lemaitre, R. N., Li, Y., Liang, J., Liu, J., Liu, K., Loh, M., Louie, T., Mägi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Mosley, T. H., Mukamal, K. J., Nalls, M. A., Nauck, M., Nelson, C. P., Sotoodehnia, N., O'Connell, J. R., Palmer, N. D., Pazoki, R., Pedersen, N. L., Peters, A., Peyser, P. A., Polasek, O., Poulter, N., Raffel, L. J., Raitakari, O. T., Reiner, A. P., Rice, T. K., Rich, S. S., Robino, A., Robinson, J. G., Rose, L. M., Rudan, I., Schmidt, C. O., Schreiner, P. J., Scott, W. R., Sever, P., Shi, Y., Sidney, S., Sims, M., Smith, B. H., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Tan, N., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Uitterlinden, A. G., Van Heemst, D., Vuckovic, D., Waldenberger, M., Wang, L., Wang, Y., Wang, Z., Wei, W. B., Williams, C., Wilson, G., Wojczynski, M. K., Yao, J., Yu, B., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Horta, B. L., Kamatani, Y., Kato, N., Kooner, J. S., Laakso, M., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Penninx, B., Pereira, A. C., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wang, Y. X., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Zheng, W., Elliott, P., North, K. E., Bouchard, C., Evans, M. K., Gudnason, V., Liu, C. T., Liu, Y., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Kardia, S. L. R., Zhu, X., Rotimi, C. N., Mook-Kanamori, D. O., Fornage, M., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Liu, J., Rotter, J. I., Gauderman, W. J., Province, M. A., Munroe, P. B., Rice, K., Chasman, D. I., Cupples, L. A., Rao, D. C. & Morrison, A. C., Jun 1 2019, In: American journal of epidemiology. 188, 6, p. 1033-1054 22 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    44 Scopus citations
  • Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

    Understanding Society Scientific group, Lifelines Cohort, COGENT-Kidney Consortium & EPIC-InterAct Consortium, Apr 1 2019, In: Nature Genetics. 51, 4, p. 636-648 13 p.

    Research output: Contribution to journalArticlepeer-review

    58 Scopus citations
  • Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

    Lifelines Cohort Study, Dec 1 2019, In: Nature communications. 10, 1, 376.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    39 Scopus citations
  • Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma

    National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 2019, In: CHEST. 156, 6, p. 1068-1079 12 p.

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • 2020

    ATRAID regulates the action of nitrogen-containing bisphosphonates on bone

    Surface, L. E., Burrow, D. T., Li, J., Park, J., Kumar, S., Lyu, C., Song, N., Yu, Z., Rajagopal, A., Bae, Y., Lee, B. H., Mumm, S., Gu, C. C., Baker, J. C., Mohseni, M., Sum, M., Huskey, M., Duan, S., Bijanki, V. N., Civitelli, R., & 18 othersGardner, M. J., McAndrew, C. M., Ricci, W. M., Gurnett, C. A., Diemer, K., Wan, F., Costantino, C. L., Shannon, K. M., Raje, N., Dodson, T. B., Haber, D. A., Carette, J. E., Varadarajan, M., Brummelkamp, T. R., Birsoy, K., Sabatini, D. M., Haller, G. & Peterson, T. R., May 20 2020, In: Science translational medicine. 12, 544, eaav9166.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

    NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium & TOPMed Lipids Working Group, Sep 1 2020, In: Nature Genetics. 52, 9, p. 969-983 15 p.

    Research output: Contribution to journalArticlepeer-review

    37 Scopus citations
  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes

    NHLBI Trans-Omics for Precision Medicine Consortium, Oct 29 2020, In: Nature. 586, 7831, p. 763-768 6 p.

    Research output: Contribution to journalArticlepeer-review

    144 Scopus citations
  • Open Access
    1 Scopus citations
  • Uncovering the complex genetics of human personality: response from authors on the PGMRA Model

    Zwir, I., Mishra, P., Del-Val, C., Gu, C. C., de Erausquin, G. A., Lehtimäki, T. & Cloninger, C. R., Oct 1 2020, In: Molecular Psychiatry. 25, 10, p. 2210-2213 4 p.

    Research output: Contribution to journalLetterpeer-review

    Open Access
    8 Scopus citations
  • 2021

    A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

    NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Oct 2021, In: Nature Genetics. 53, 10, p. 1504-1516 13 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes (Nature, (2020), 586, 7831, (763-768), 10.1038/s41586-020-2819-2)

    NHLBI Trans-Omics for Precision Medicine Consortium, Mar 25 2021, In: Nature. 591, 7851, p. E27

    Research output: Contribution to journalComment/debate

    Open Access
    2 Scopus citations
  • Open Access
  • Bk channels regulate LPS-induced CCL-2 release from human pulmonary endothelial cells

    Zyrianova, T., Lopez, B., Liao, A., Gu, C., Wong, L., Ottolia, M., Olcese, R. & Schwingshackl, A., 2021, In: American Journal of Respiratory Cell and Molecular Biology. 64, 2, p. 224-234 11 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

    NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium & FinnGen, Dec 1 2021, In: Nature communications. 12, 1, 2182.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Donor-specific phenotypic variation in hiPSC cardiomyocyte-derived exosomes impacts endothelial cell function

    Turner, A., Aggarwal, P., Matter, A., Olson, B., Charles Gu, C., Hunt, S. C., Lewis, C. E., Arnett, D. K., Lorier, R. & Broeckel, U., 2021, In: American Journal of Physiology - Heart and Circulatory Physiology. 320, 3, p. H954-H968

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

    Lifelines Cohort Study, Jun 2021, In: Molecular Psychiatry. 26, 6, p. 2111-2125 15 p.

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • Genome sequencing unveils a regulatory landscape of platelet reactivity

    NHLBI Trans-Omics for Precision (TOPMed) Consortium, Dec 2021, In: Nature communications. 12, 1, 3626.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

    Lifelines Cohort Study, Jan 14 2021, In: Human Genetics and Genomics Advances. 2, 1, 100013.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

    NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Feb 11 2021, In: Nature. 590, 7845, p. 290-299 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    242 Scopus citations
  • Three genetic–environmental networks for human personality

    Zwir, I., Del-Val, C., Arnedo, J., Pulkki-Råback, L., Konte, B., Yang, S. S., Romero-Zaliz, R., Hintsanen, M., Cloninger, K. M., Garcia, D., Svrakic, D. M., Lester, N., Rozsa, S., Mesa, A., Lyytikäinen, L. P., Giegling, I., Kähönen, M., Martinez, M., Seppälä, I., Raitoharju, E., & 10 othersde Erausquin, G. A., Mamah, D., Raitakari, O., Rujescu, D., Postolache, T. T., Gu, C. C., Sung, J., Lehtimäki, T., Keltikangas-Järvinen, L. & Cloninger, C. R., Aug 2021, In: Molecular Psychiatry. 26, 8, p. 3858-3875 18 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    34 Scopus citations
  • Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

    NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 1 2021, In: Nature communications. 12, 1, 3506.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify MYRIP, TRAPPC11, and SLC27A6 of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population

    Irvin, M. R., Aggarwal, P., Claas, S. A., de las Fuentes, L., Do, A. N., Gu, C. C., Matter, A., Olson, B. S., Patki, A., Schwander, K., Smith, J. D., Srinivasasainagendra, V., Tiwari, H. K., Turner, A. J., Nickerson, D. A., Rao, D. C., Broeckel, U. & Arnett, D. K., Feb 19 2021, In: Frontiers in Genetics. 12, 588452.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

    TOPMed Sleep Working Group & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 2021, In: Genome medicine. 13, 1, 136.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • 2022

    Gene-lifestyle interactions in the genomics of human complex traits

    the CHARGE Gene-Lifestyle Interactions Working Group, Jun 2022, In: European Journal of Human Genetics. 30, 6, p. 730-739 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations