Research output per year
Research output per year
Personal profile
Research interests
I am interested in study male fertility and male contraception. The semen analysis is a poor predictor of sperm fertility capacity and we are looking at other parameters (sperm membrane potential, intracellular calcium and pH as better predictors (biomarkers) of sperm fertility capacity. I am also interested in understanding the underlying causes of male idiopathic infertility and validating new targets for male contraception.
Available to Mentor:
- PhD/MSTP Students
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Collaborations and top research areas from the last five years
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Differential role of bovine serum albumin and HCO32 in the regulation of GSK3 alpha during mouse sperm capacitation
Mohanty, G., Sanchez-Cardenas, C., Paudel, B., Tourzani, D. A., Salicioni, A. M., Santi, C. M., Gervasi, M. G., Pilsner, J. R., Darszon, A. & Visconti, P. E., Mar 1 2024, In: Molecular human reproduction. 30, 3, gaae007.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Membrane potential hyperpolarization: a critical factor in acrosomal exocytosis and fertilization in sperm within the female reproductive tract
Balestrini, P. A., Sulzyk, V., Jabloñski, M., Schiavi-Ehrenhaus, L. J., González, S. N., Ferreira, J. J., Gómez-Elías, M. D., Pomata, P., Luque, G. M., Krapf, D., Cuasnicu, P. S., Santi, C. M. & Buffone, M. G., 2024, In: Frontiers in Cell and Developmental Biology. 12, 1386980.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function
Lyon, M., Li, P., Ferreira, J. J., Lazarenko, R. M., Kharade, S. V., Kramer, M., McClenahan, S. J., Days, E., Bauer, J. A., Spitznagel, B. D., Weaver, C. D., Alvarez, A. B., Puga Molina, L. C., Lybaert, P., Khambekar, S., Liu, A., Lindsley, C. W., Denton, J. & Santi, C. M., Jan 24 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 4, e2212338120.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
SLO3: A Conserved Regulator of Sperm Membrane Potential
Lyon, M. D., Ferreira, J. J., Li, P., Bhagwat, S., Butler, A., Anderson, K., Polo, M. & Santi, C. M., Jul 2023, In: International journal of molecular sciences. 24, 13, 11205.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
The effect of Dnaaf5 gene dosage on primary ciliary dyskinesia phenotypes
Horani, A., Gupta, D. K., Xu, J., Xu, H., Puga-Molina, L. D. C., Santi, C. M., Ramagiri, S., Brennan, S. K., Pan, J., Koenitzer, J. R., Huang, T., Hyland, R. M., Gunsten, S. P., Tzeng, S. C., Strahle, J. M., Mill, P., Mahjoub, M. R., Dutcher, S. K. & Brody, S. L., 2023, In: JCI Insight. 8, 11, e168836.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations