Willing to Mentor

    Available to Mentor:

    High School Students, Undergraduate Students, Post-Baccalaureate Students, PhD/MSTP Students

    • Source: Scopus
    20102022

    Research activity per year

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    Research interests

    Approximately 20,000 adult patients develop Acute Myeloid Leukemia (AML) each year; these patients have a ~25% chance to survive 5 years after their initial diagnosis. This is largely due to relapses, refractory disease, or serious side effects associated with current therapies (i.e. chemotherapy and/or blood stem cell transplantation). In order to develop better treatment strategies, we must first understand the underlying molecular mechanisms that initiate and maintain the disease.

    Our research utilizes state-of-the-art techniques to elucidate the mechanisms that control the aberrant self-renewal and transformation of myeloid progenitor cells. A greater understanding of these processes may help us to design novel therapeutic strategies to more specifically and effectively treat AML. In addition, identifying the genes and mechanisms that control self-renewal could have important implications for regenerative medicine and stem cell biology.

    Available to Mentor:

    • High School Students
    • Undergraduate Students
    • Post-Baccalaureate Students
    • PhD/MSTP Students

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