Research output per year
Research output per year
- 1 - 50 out of 55 results
Search results
-
2024
VODKA2: a fast and accurate method to detect nonstandard viral genomes from large RNA-seq data sets
Achouri, E., Felt, S. A., Hackbart, M., Rivera-Espinal, N. S. & López, C. B., Jan 2024, In: RNA. 30, 1, p. 16-25 10 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2023
Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity
González Aparicio, L. J., Yang, Y., Hackbart, M. & López, C. B., Nov 2023, In: PLoS biology. 21, 11 November, e3002381.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Respiratory viruses: New frontiers—a Keystone Symposia report
Cable, J., Sun, J., Cheon, I. S., Vaughan, A. E., Castro, I. A., Stein, S. R., López, C. B., Gostic, K. M., Openshaw, P. J. M., Ellebedy, A. H., Wack, A., Hutchinson, E., Thomas, M. M., Langlois, R. A., Lingwood, D., Baker, S. F., Folkins, M., Foxman, E. F., Ward, A. B. & Schwemmle, M. & 7 others, , Apr 2023, In: Annals of the New York Academy of Sciences. 1522, 1, p. 60-73 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2022
Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back viral genome population followed by selection
Felt, S. A., Achouri, E., Faber, S. R. & López, C. B., 2022, In: Virus Evolution. 8, 2, veac091.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis
Hiller, B. E., Yin, Y., Perng, Y. C., de Araujo Castro, Í., Fox, L. E., Locke, M. C., Monte, K. J., López, C. B., Ornitz, D. M. & Lenschow, D. J., Jun 2022, In: PLoS pathogens. 18, 6, e1010228.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Non-standard viral genome-derived RNA activates TLR3 and type I IFN signaling to induce cDC1-dependent CD8+ T-cell responses during vaccination in mice
Fisher, D. G., Gnazzo, V., Holthausen, D. J. & López, C. B., Nov 28 2022, In: Vaccine. 40, 50, p. 7270-7279 10 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2021
Detection of respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes
Felt, S. A., Sun, Y., Jozwik, A., Paras, A., Habibi, M. S., Nickle, D., Anderson, L., Achouri, E., Feemster, K. A., Cárdenas, A. M., Turi, K. N., Chang, M., Hartert, T. V., Sengupta, S., Chiu, C. & López, C. B., May 2021, In: Nature microbiology. 6, 5, p. 672-681 10 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
2020
Distinct Chronic Post-Viral Lung Diseases upon Infection with Influenza or Parainfluenza Viruses Differentially Impact Superinfection Outcome
Garcia, G. L., Valenzuela, A., Manzoni, T., Vaughan, A. E. & López, C. B., Mar 2020, In: American Journal of Pathology. 190, 3, p. 543-553 11 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis
Zhang, T., Yin, C., Boyd, D. F., Quarato, G., Ingram, J. P., Shubina, M., Ragan, K. B., Ishizuka, T., Crawford, J. C., Tummers, B., Rodriguez, D. A., Xue, J., Peri, S., Kaiser, W. J., López, C. B., Xu, Y., Upton, J. W., Thomas, P. G., Green, D. R. & Balachandran, S., Mar 19 2020, In: Cell. 180, 6, p. 1115-1129.e13Research output: Contribution to journal › Article › peer-review
Open Access320 Scopus citations -
The viral polymerase complex mediates the interaction of viral ribonucleoprotein complexes with recycling endosomes during sendai virus assembly
Genoyer, E., Kulej, K., Hung, C. T., Thibault, P. A., Azarm, K., Takimoto, T., Garcia, B. A., Lee, B., Lakdawala, S., Weitzman, M. D. & López, C. B., Jul 1 2020, In: mBio. 11, 4, p. 1-20 20 p., e02028-20.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2019
A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes
Sun, Y., Kim, E. J., Felt, S. A., Taylor, L. J., Agarwal, D., Grant, G. R. & Lopez, C. B., 2019, In: PLoS pathogens. 15, 4, e1007707.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Circadian control of lung inflammation in influenza infection
Sengupta, S., Tang, S. Y., Devine, J. C., Anderson, S. T., Nayak, S., Zhang, S. L., Valenzuela, A., Fisher, D. G., Grant, G. R., López, C. B. & FitzGerald, G. A., Dec 1 2019, In: Nature communications. 10, 1, 4107.Research output: Contribution to journal › Article › peer-review
Open Access100 Scopus citations -
Defective viral genomes alter how Sendai virus interacts with cellular trafficking machinery, leading to heterogeneity in the production of viral particles among infected cells
Genoyer, E. & López, C. B., Feb 1 2019, In: Journal of virology. 93, 4, e0157918.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
The Impact of Defective Viruses on Infection and Immunity
Genoyer, E. & López, C. B., Sep 29 2019, In: Annual Review of Virology. 6, p. 547-566 20 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
2018
Virus-derived immunostimulatory RNA induces type I IFN-dependent antibodies and T-cell responses during vaccination
Fisher, D. G., Coppock, G. M. & López, C. B., Jun 27 2018, In: Vaccine. 36, 28, p. 4039-4045 7 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
2017
IL-27 LIMITS TYPE 2 IMMUNOPATHOLOGY FOLLOWING PARAINFLUENZA VIRUS INFECTION
Muallem, G., Wagage, S., Sun, Y., DeLong, J. H., Valenzuela, A., Christian, D. A., Harms Pritchard, G., Fang, Q., Buza, E. L., Jain, D., Elloso, M. M., López, C. B. & Hunter, C. A., Jan 2017, In: PLoS pathogens. 13, 1, e1006173.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence
Xu, J., Sun, Y., Li, Y., Ruthel, G., Weiss, S. R., Raj, A., Beiting, D. & López, C. B., Dec 1 2017, In: Nature communications. 8, 1, 799.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
The innate immune response to RSV: Advances in our understanding of critical viral and host factors
Sun, Y. & López, C. B., Jan 11 2017, In: Vaccine. 35, 3, p. 481-488 8 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
2016
Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death
Philip, N. H., DeLaney, A., Peterson, L. W., Santos-Marrero, M., Grier, J. T., Sun, Y., Wynosky-Dolfi, M. A., Zwack, E. E., Hu, B., Olsen, T. M., Rongvaux, A., Pope, S. D., López, C. B., Oberst, A., Beiting, D. P., Henao-Mejia, J. & Brodsky, I. E., Oct 2016, In: PLoS pathogens. 12, 10, e1005910.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
lncRHOXF1, a long noncoding RNA from the X chromosome that suppresses viral response genes during development of the early human placenta
Penkala, I., Wang, J., Syrett, C. M., Goetzl, L., López, C. B. & Anguera, M. C., Jun 1 2016, In: Molecular and cellular biology. 36, 12, p. 1764-1775 12 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Propagation and characterization of influenza virus stocks that lack high levels of defective viral genomes and hemagglutinin mutations
Xue, J., Chambers, B. S., Hensley, S. E. & López, C. B., Mar 23 2016, In: Frontiers in Microbiology. 7, MAR, 326.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus
Nogusa, S., Thapa, R. J., Dillon, C. P., Liedmann, S., Oguin, T. H., Ingram, J. P., Rodriguez, D. A., Kosoff, R., Sharma, S., Sturm, O., Verbist, K., Gough, P. J., Bertin, J., Hartmann, B. M., Sealfon, S. C., Kaiser, W. J., Mocarski, E. S., López, C. B., Thomas, P. G. & Oberst, A. & 2 others, , Jul 13 2016, In: Cell Host and Microbe. 20, 1, p. 13-24 12 p.Research output: Contribution to journal › Article › peer-review
Open Access281 Scopus citations -
2015
Identification of a natural viral RNA motif that optimizes sensing of viral RNA by RIG-I
Xu, J., Mercado-López, X., Grier, J. T., Kim, W. K., Chun, L. F., Irvine, E. B., Duany, Y. D. T., Kell, A., Hur, S., Gale, M., Raj, A. & López, C. B., 2015, In: mBio. 6, 5, e01265-15.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans
Sun, Y., Jain, D., Koziol-White, C. J., Genoyer, E., Gilbert, M., Tapia, K., Panettieri, R. A., Hodinka, R. L. & López, C. B., 2015, In: PLoS pathogens. 11, 9, p. 1-21 21 p., e1005122.Research output: Contribution to journal › Article › peer-review
Open Access97 Scopus citations -
In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus
Benitez, A. A., Panis, M., Xue, J., Varble, A., Shim, J. V., Frick, A. L., López, C. B., Sachs, D. & tenOever, B. R., Jun 23 2015, In: Cell Reports. 11, 11, p. 1714-1726 13 p.Research output: Contribution to journal › Article › peer-review
Open Access65 Scopus citations -
2014
Defective viral genomes: Critical danger signals of viral infections
López, C. B., 2014, In: Journal of virology. 88, 16, p. 8720-8723 4 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Deficiency of melanoma differentiation-associated protein 5 results in exacerbated chronic postviral lung inflammation
Kim, W. K., Jain, D., Sánchez, M. D., Koziol-White, C. J., Matthews, K., Ge, M. Q., Haczku, A., Panettieri, R. A., Frieman, M. B. & López, C. B., Feb 15 2014, In: American journal of respiratory and critical care medicine. 189, 4, p. 437-448 12 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
2013
Defective Viral Genomes Arising In Vivo Provide Critical Danger Signals for the Triggering of Lung Antiviral Immunity
Tapia, K., Kim, W. K., Sun, Y., Mercado-López, X., Dunay, E., Wise, M., Adu, M. & López, C. B., Oct 2013, In: PLoS pathogens. 9, 10, e1003703.Research output: Contribution to journal › Article › peer-review
Open Access112 Scopus citations -
Highly immunostimulatory RNA derived from a Sendai virus defective viral genome
Mercado-López, X., Cotter, C. R., Kim, W. K., Sun, Y., Muñoz, L., Tapia, K. & López, C. B., Nov 19 2013, In: Vaccine. 31, 48, p. 5713-5721 9 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
2012
Granulocyte colony-stimulating factor protects mice during respiratory virus infections
Hermesh, T., Moran, T. M., Jain, D. & López, C. B., May 16 2012, In: PloS one. 7, 5, e37334.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2011
Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells
Leung, L. W., Park, M. S., Martinez, O., Valmas, C., López, C. B. & Basler, C. F., Oct 2011, In: Immunology and Cell Biology. 89, 7, p. 792-802 11 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
Proapoptotic and antiapoptotic actions of Stat1 versus Stat3 underlie neuroprotective and immunoregulatory functions of IL-11
Zhang, J., Zhang, Y., Dutta, D. J., Argaw, A. T., Bonnamain, V., Seto, J., Braun, D. A., Zameer, A., Hayot, F., Lop̀ez, C. B., Raine, C. S. & John, G. R., Aug 1 2011, In: Journal of Immunology. 187, 3, p. 1129-1141 13 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Role of cell-to-cell variability in activating a positive feedback antiviral response in human dendritic cells
Hu, J., Nudelman, G., Shimoni, Y., Kumar, M., Ding, Y., López, C., Hayot, F., Wetmur, J. G. & Sealfon, S. C., 2011, In: PloS one. 6, 2, e16614.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling
Cotter, C. R., Kim, W. K., Nguyen, M. L., Yount, J. S., López, C. B., Blaho, J. A. & Moran, T. M., Dec 2011, In: Journal of virology. 85, 23, p. 12662-12672 11 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
2010
Antiviral instruction of bone marrow leukocytes during respiratory viral infections
Hermesh, T., Moltedo, B., Moran, T. M. & López, C. B., May 20 2010, In: Cell Host and Microbe. 7, 5, p. 343-353 11 p.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3
Yount, J. S., Moltedo, B., Yang, Y. Y., Charron, G., Moran, T. M., López, C. B. & Hang, H. C., Aug 2010, In: Nature Chemical Biology. 6, 8, p. 610-614 5 p.Research output: Contribution to journal › Article › peer-review
Open Access295 Scopus citations -
The virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells
Cotter, C. R., Nguyen, M. L., Yount, J. S., López, C. B., Blaho, J. A. & Moran, T. M., Feb 18 2010, In: PloS one. 5, 2, e8684.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
2009
Cutting edge: Stealth influenza virus replication precedes the initiation of adaptive immunity
Moltedo, B., López, C. B., Pazos, M., Becker, M. I., Hermesh, T. & Moran, T. M., Sep 15 2009, In: Journal of Immunology. 183, 6, p. 3569-3573 5 p.Research output: Contribution to journal › Article › peer-review
Open Access83 Scopus citations -
IL-11 regulates autoimmune demyelination
Gurfein, B. T., Zhang, Y., López, C. B., Argaw, A. T., Zameer, A., Moran, T. M. & John, G. R., Oct 1 2009, In: Journal of Immunology. 183, 7, p. 4229-4240 12 p.Research output: Contribution to journal › Article › peer-review
Open Access66 Scopus citations -
2008
Estrogen inhibits dendritic cell maturation to RNA viruses
Escribese, M. M., Kraus, T., Rhee, E., Fernandez-Sesma, A., López, C. B. & Moran, T. M., Dec 1 2008, In: Blood. 112, 12, p. 4574-4584 11 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to sendai virus defective interfering particles
Yount, J. S., Gitlin, L., Moran, T. M. & López, C. B., Apr 1 2008, In: Journal of Immunology. 180, 7, p. 4910-4918 9 p.Research output: Contribution to journal › Article › peer-review
Open Access105 Scopus citations -
2007
Cytokine-independent upregulation of MDA5 in viral infection
Yount, J. S., Moran, T. M. & López, C. B., Jul 2007, In: Journal of virology. 81, 13, p. 7316-7319 4 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
2006
A novel role for viral-defective interfering particles in enhancing dendritic cell maturation
Yount, J. S., Kraus, T. A., Horvath, C. M., Moran, T. M. & López, C. B., Oct 1 2006, In: Journal of Immunology. 177, 7, p. 4503-4513 11 p.Research output: Contribution to journal › Article › peer-review
Open Access91 Scopus citations -
Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine
Trumpfheller, C., Finke, J. S., López, C. B., Moran, T. M., Moltedo, B., Soares, H., Huang, Y., Schlesinger, S. J., Chae, G. P., Nussenzweig, M. C., Granelli-Piperno, A. & Steinman, R. M., Mar 20 2006, In: Journal of Experimental Medicine. 203, 3, p. 607-617 11 p.Research output: Contribution to journal › Article › peer-review
Open Access194 Scopus citations -
Sendai virus infection induces efficient adaptive immunity independently of type I interferons
López, C. B., Yount, J. S., Hermesh, T. & Moran, T. M., May 2006, In: Journal of virology. 80, 9, p. 4538-4545 8 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
2004
Characterization and distribution of colonic dendritic cells in Crohn's disease
Silva, M. A., López, C. B., Riverin, F., Oligny, L., Menezes, J. & Seidman, E. G., Sep 2004, In: Inflammatory bowel diseases. 10, 5, p. 504-512 9 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
TLR-independent induction of dendritic cell maturation and adaptive immunity by negative-strand RNA viruses
Lopez, C. B., Moltedo, B., Alexopoulou, L., Bonifaz, L., Flavell, R. A. & Moran, T. M., Dec 1 2004, In: Journal of Immunology. 173, 11, p. 6882-6889 8 p.Research output: Contribution to journal › Article › peer-review
Open Access132 Scopus citations -
2003
Type I interferon induction pathway, but not released interferon, participates in the maturation of dendritic cells induced by negative-strand RNA viruses
López, C. B., García-Sastre, A., Williams, B. R. G. & Moran, T. M., Apr 1 2003, In: Journal of Infectious Diseases. 187, 7, p. 1126-1136 11 p.Research output: Contribution to journal › Article › peer-review
Open Access98 Scopus citations -
2002
Antiviral immunity and the role of dendritic cells
López, C. B., Moran, T. M., Schulman, J. L. & Fernandez-Sesma, A., Jul 2002, In: International Reviews of Immunology. 21, 4-5, p. 339-353 15 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2001
Myeloid dendritic cells stimulate both TH1 and TH2 immune responses depending on the nature of the antigen
López, C. B., Fernandez-Sesma, A., Schulman, J. L. & Moran, T. M., 2001, In: Journal of Interferon and Cytokine Research. 21, 9, p. 763-773 11 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations