Personal profile

Research interests

We use a multidisciplinary approach to study the intimate relationship of a virus and the organism it infects. We focus on dissecting the early events that determine the course of infection with various respiratory viruses. The laboratory places particular attention to the role of defective viral genomes generated during virus replication in determining the outcome of infection.

Available to Mentor:

  • PhD/MSTP Students

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Collaborations and top research areas from the last five years

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  • Selection of nonstandard viral genomes during the evolution of RNA viruses: A virus survival strategy or a pesky inconvenience?

    González Aparicio, L. J. & López, C. B., Jan 2024, Advances in Virus Research. Academic Press Inc., p. 39-61 23 p. (Advances in Virus Research; vol. 119).

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  • VODKA2: a fast and accurate method to detect nonstandard viral genomes from large RNA-seq data sets

    Achouri, E., Felt, S. A., Hackbart, M., Rivera-Espinal, N. S. & López, C. B., Jan 2024, In: RNA. 30, 1, p. 16-25 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity

    González Aparicio, L. J., Yang, Y., Hackbart, M. & López, C. B., Nov 2023, In: PLoS biology. 21, 11 November, e3002381.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Respiratory viruses: New frontiers—a Keystone Symposia report

    Cable, J., Sun, J., Cheon, I. S., Vaughan, A. E., Castro, I. A., Stein, S. R., López, C. B., Gostic, K. M., Openshaw, P. J. M., Ellebedy, A. H., Wack, A., Hutchinson, E., Thomas, M. M., Langlois, R. A., Lingwood, D., Baker, S. F., Folkins, M., Foxman, E. F., Ward, A. B., Schwemmle, M., & 7 othersRussell, A. B., Chiu, C., Ganti, K., Subbarao, K., Sheahan, T. P., Penaloza-MacMaster, P. & Eddens, T., Apr 2023, In: Annals of the New York Academy of Sciences. 1522, 1, p. 60-73 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Virology under the Microscope-a Call for Rational Discourse

    Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., & 136 othersCameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W. P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S. L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W. A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J. H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S. & Yurochko, A., Jan 2023, In: mBio. 14, 1

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    2 Scopus citations