Carlos Cruchaga

2023

Author Correction: Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2) (npj Parkinson's Disease, (2023), 9, 1, (100), 10.1038/s41531-023-00526-9)

the Global Parkinson’s Genetic Program (GP2) & Cruchaga, C., Dec 2023, In: npj Parkinson's Disease. 9, 1, 133.

Research output: Contribution to journal › Comment/debate

Open Access

Erratum: Comparative Analysis of Alzheimer's Disease Cerebrospinal Fluid Biomarkers Measurement by Multiplex SOMAscan Platform and Immunoassay-Based Approach (Journal of Alzheimer's Disease (2022) 89 (193–207) DOI: 10.3233/JAD-220399)

Timsina, J., Gomez-Fonseca, D., Wang, L., Do, A., Western, D., Alvarez, I., Aguilar, M., Pastor, P., Henson, R. L., Herries, E., Xiong, C., Schindler, S., Fagan, A. M., Bateman, R. J., Farlow, M., Morris, J., Perrin, R. J., Moulder, K., Hassenstab, J. & Voglein, J. & 4 others, Chhatwal, J., Mori, H., Ju Sung, Y. & Cruchaga, C., 2023, In: Journal of Alzheimer's Disease. 91, 2, p. 911 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

2022

AD-causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains.

Schultz, S. A., Allegri, R. F., Schultz, A. P., Goate, A., Levey, A. I., Fagan, A. M., Hanseeuw, B. J., Koeppe, R. A., Gordon, B. A., Cruchaga, C., Karch, C. M., Chen, C. D., Xiong, C., Jack, C. R., Fitzpatrick, C. D., McDade, E., Chui, H. C., Mori, H., Lee, J. H. & Noble, J. M. & 23 others, Hassenstab, J. J., Levin, J., Morris, J. C., Johnson, K. A., Liu, L., Farlow, M. R., Jucker, M., Farrell, M. E., Graff-Radford, N. R., Joseph-Mathurin, N., Fox, N. C., Schofield, P. R., Martins, R. N., Sanchez-Valle, R., Perrin, R., Berman, S., Salloway, S. P., Shirzadi, Z., Rosa-Neto, P., Benzinger, T. L. S., Bateman, R. J., Sperling, R. A. & Chhatwal, J. P., Dec 2022, In: Alzheimer's and Dementia. 18, S1, e068221.

Research output: Contribution to journal › Comment/debate

1 Scopus citations

ADSP Functional Genomics: from gene, to function to mechanisms and targets

Cruchaga, C., Dec 2022, In: Alzheimer's and Dementia. 18, S4, e066436.

Research output: Contribution to journal › Comment/debate

A large-scale genome-wide association study of early-onset Alzheimer disease

Neupane, A., da Fonseca, E. L., Kurup, J. T., Pericak-Vance, M. A., Martin, E. R., Schellenberg, G. D., Reitz, C., Beecham, G. W., Cruchaga, C. & Fernandez, V., Dec 2022, In: Alzheimer's and Dementia. 18, S4, e064268.

Research output: Contribution to journal › Comment/debate

Integrating functional genomics with genetics to understand the biology of ALS and FTD

Cruchaga, C., Apr 8 2022, In: Med. 3, 4, p. 226-227 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

Pleiotropic effect of LRRK2 on Parkinson-associated proteins and processing of pathological alpha-synuclein in myeloid cells

Nykanen, L.N.-P., Yang, C., Harari, O., Davis, G., Cruchaga, C. & Benitez Viloria, B. A., Dec 2022, In: Alzheimer's and Dementia. 18, S4, e063954.

Research output: Contribution to journal › Comment/debate

Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries (Nature, (2022), 611, 7934, (115-123), 10.1038/s41586-022-05165-3)

PRECISE4Q Consortium, FinnGen Consortium, NINDS Stroke Genetics Network (SiGN), MEGASTROKE Consortium, SIREN Consortium, China Kadoorie Biobank Collaborative Group, VA Million Veteran Program, International Stroke Genetics Consortium (ISGC), Biobank Japan, CHARGE Consortium, GIGASTROKE Consortium, COMPASS Consortium, INVENT Consortium, Dutch Parelsnoer Initiative (PSI) Cerebrovascular Disease Study Group, Estonian Biobank & Cruchaga, C., Dec 1 2022, In: Nature. 612, 7938, p. E7

Research output: Contribution to journal › Comment/debate

Open Access

2 Scopus citations

2021

Erratum: Rare and de novo coding variants in chromodomain genes in Chiari I malformation (The American Journal of Human Genetics (2021) 108(1) (100–114), (S0002929720304377), (10.1016/j.ajhg.2020.12.001))

Sadler, B., Wilborn, J., Antunes, L., Kuensting, T., Hale, A. T., Gannon, S. R., McCall, K., Cruchaga, C., Harms, M., Voisin, N., Reymond, A., Cappuccio, G., Brunetti-Pierri, N., Tartaglia, M., Niceta, M., Leoni, C., Zampino, G., Ashley-Koch, A., Urbizu, A. & Garrett, M. E. & 11 others, Soldano, K., Macaya, A., Conrad, D., Strahle, J., Dobbs, M. B., Turner, T. N., Shannon, C. N., Brockmeyer, D., Limbrick, D. D., Gurnett, C. A. & Haller, G., Mar 4 2021, In: American journal of human genetics. 108, 3, p. 530-531 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

3 Scopus citations

Erratum: Rare and de novo coding variants in chromodomain genes in Chiari I malformation (The American Journal of Human Genetics (2021) 108(1) (100–114), (S0002929720304377), (10.1016/j.ajhg.2020.12.001))

Sadler, B., Wilborn, J., Antunes, L., Kuensting, T., Hale, A. T., Gannon, S. R., McCall, K., Cruchaga, C., Harms, M., Voisin, N., Reymond, A., Cappuccio, G., Brunetti-Pierri, N., Tartaglia, M., Niceta, M., Leoni, C., Zampino, G., Ashley-Koch, A., Urbizu, A. & Garrett, M. E. & 11 others, Soldano, K., Macaya, A., Conrad, D., Strahle, J., Dobbs, M. B., Turner, T. N., Shannon, C. N., Brockmeyer, D., Limbrick, D. D., Gurnett, C. A. & Haller, G., Feb 4 2021, In: American journal of human genetics. 108, 2, p. 368 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

3 Scopus citations

2020

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation (Molecular Psychiatry, (2020), 25, 8, (1859-1875), 10.1038/s41380-018-0112-7)

Alzheimer’s Disease Sequencing Project, Aug 1 2020, In: Molecular Psychiatry. 25, 8, p. 1901-1903 3 p.

Research output: Contribution to journal › Comment/debate

Open Access

6 Scopus citations

Correction to: Overlapping genetic architecture between Parkinson disease and melanoma (Acta Neuropathologica, (2020), 139, 2, (347-364), 10.1007/s00401-019-02110-z)

23andMe Research Team, Melanoma-Meta-analysis Consortium, GenoMEL Consortium, Essen-Heidelberg Investigators, SDH Study Group, Q-MEGA and QTWIN Investigators, AMFS Investigators & ATHENS Melanoma Study Group, May 1 2020, In: Acta Neuropathologica. 139, 5, p. 963 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity (Acta Neuropathologica, (2019), 138, 2, (237-250), 10.1007/s00401-019-02026-8)

EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB), The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group & DESGESCO (Dementia Genetics Spanish Consortium), May 1 2020, In: Acta Neuropathologica. 139, 5, p. 959-962 4 p.

Research output: Contribution to journal › Comment/debate

Open Access

2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Sep 1 2019, In: Nature Genetics. 51, 9, p. 1423-1424 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

47 Scopus citations

Publisher correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes(Nature Genetics, (2018) 50, 4, (524-537), 10.1038/s41588-018-0058-3)

AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STARNET, BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC), METASTROKE Consortium, Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study & MEGASTROKE Consortium, 2019, In: Nature Genetics. 51, 7, p. 1192-1193 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

11 Scopus citations

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (Nature Genetics, (2018), 50, 3, (381-389), 10.1038/s41588-018-0059-2)

GERAD1 Consortium & CRESTAR Consortium, Jul 1 2019, In: Nature Genetics. 51, 7, p. 1193 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

11 Scopus citations

2018

Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience

Alzheimer's Disease Neuroimaging Initiative, Jan 12 2018, In: Genome medicine. 10, 1, 4.

Research output: Contribution to journal › Comment/debate

Open Access

2 Scopus citations

2014

The epigenetic landscape of Alzheimer's disease

Lord, J. & Cruchaga, C., Sep 2014, In: Nature neuroscience. 17, 9, p. 1138-1140 3 p.

Research output: Contribution to journal › Comment/debate

Open Access

93 Scopus citations

TMEM106B: A strong FTLD disease modifier

Deming, Y. & Cruchaga, C., Mar 2014, In: Acta Neuropathologica. 127, 3, p. 419-422 4 p.

Research output: Contribution to journal › Comment/debate

Open Access

20 Scopus citations

2013

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093))

Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Singh Pahwa, J., Moskvina, V., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J., Proitsi, P., Lupton, M. K., Brayne, C. & Rubinsztein, D. C. & 66 others, Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Schürmann, B., Van Den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Sleegers, K., Bettens, K., Engelborghs, S., De Deyn, D. P., Van Broeckhoven, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K. H., Klopp, N., Wichmann, H. E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Holmans, P. A., O'Donovan, M., Owen, M. J. & Williams, J., Jun 2013, In: Nature Genetics. 45, 6, p. 712 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

7 Scopus citations

2009

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics) (2009) 41 (1088-1093))

Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J., Proitsi, P., Lupton, M. K., Brayne, C. & Rubinsztein, D. C. & 67 others, Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Schürmann, B., Heun, R., Van Den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Sleegers, K., Bettens, K., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Guerreiro, R., Nöthen, M. M., Moebus, S., Jöckel, K. H., Klopp, N., Wichmann, H. E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Holmans, P. A., O'Donovan, M., Owen, M. J. & Williams, J., Oct 1 2009, In: Nature Genetics. 41, 10, p. 1156 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

5 Scopus citations

Carlos Cruchaga

Research output

Search results