Carla Yuede

Associate Professor of Psychiatry, Associate Professor of Neurology, Associate Professor of Neuroscience

  • 894 Citations
20052020

Research output per year

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Personal profile

Research interests

My research involves combining techniques to uncover aspects about neurodegenerative disease processes. I am primarily focused on the factors influencing brain Aß dynamics in mouse models of AD, particularly in relation to synaptic activity. Our long-term goal is to understand the pathways and risk factors involved in Aß generation and accumulation in the brain, with the hope of identifying effective therapeutic targets. I am also Co-Director of the Animal Behavior Core at Washington University where I am involved in helping investigators design and interpret behavioral function in many animal models of disease. My research interests involve behavioral phenotyping of new genetic models, as well as evaluating functional effects of specific treatment strategies on diverse models of neurological disorders.

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Research Output

  • 894 Citations
  • 21 Article
  • 2 Review article

Exercise training results in lower amyloid plaque load and greater cognitive function in an intensity dependent manner in the tg2576 mouse model of alzheimer’s disease

Thomas, R., Zimmerman, S. D., Yuede, K. M., Cirrito, J. R., Tai, L. M., Timson, B. F. & Yuede, C. M., Feb 2020, In : Brain Sciences. 10, 2, 88.

Research output: Contribution to journalArticle

Open Access
  • Repeated neonatal isoflurane exposures in the mouse induce apoptotic degenerative changes in the brain and relatively mild long-term behavioral deficits

    Maloney, S. E., Yuede, C. M., Creeley, C. E., Williams, S. L., Huffman, J. N., Taylor, G. T., Noguchi, K. N. & Wozniak, D. F., Dec 1 2019, In : Scientific reports. 9, 1, 2779.

    Research output: Contribution to journalArticle

    Open Access
  • 8 Scopus citations
  • 3 Scopus citations

    Characterization of a Mouse Model of Börjeson-Forssman-Lehmann Syndrome

    Cheng, C., Deng, P. Y., Ikeuchi, Y., Yuede, C., Li, D., Rensing, N., Huang, J., Baldridge, D., Maloney, S. E., Dougherty, J. D., Constantino, J., Jahani-Asl, A., Wong, M., Wozniak, D. F., Wang, T., Klyachko, V. A. & Bonni, A., Nov 6 2018, In : Cell Reports. 25, 6, p. 1404-1414.e6

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations
    Open Access
  • 9 Scopus citations