Carla Siegfried

2024

SDPR expression in human trabecular meshwork and its potential role in racial disparities of glaucoma

Shui, Y. B., Liu, Y., Huang, A. J. W. & Siegfried, C. J., Dec 2024, In: Scientific reports. 14, 1, 10258.

Research output: Contribution to journal › Article › peer-review

Open Access

Understanding racial disparities of glaucoma

Barquet-Pizá, V. & Siegfried, C. J., Mar 1 2024, In: Current Opinion in Ophthalmology. 35, 2, p. 97-103 7 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

2022

Racial Disparities in Glaucoma: From Epidemiology to Pathophysiology

Siegfried, C. J. & Shui, Y. B., Jan 1 2022, In: Missouri Medicine. 119, 1, p. 49-54 6 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Trabecular Meshwork Mitochondrial Function and Oxidative Stress: Clues to Racial Disparities of Glaucoma

Wu, H., Shui, Y. B., Liu, Y., Liu, X. & Siegfried, C. J., Mar 2022, In: Ophthalmology Science. 2, 1, 100107.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

2021

Compositional Analysis of Extracellular Aggregates in the Eyes of Patients with Exfoliation Syndrome and Exfoliation Glaucoma

de Maria, A., Zientek, K. D., David, L. L., Wilmarth, P. A., Bhorade, A. M., Harocopos, G. J., Huang, A. J. W., Hong, A. R., Siegfried, C. J., Tsai, L. M., Sheybani, A. & Bassnett, S., Dec 2021, In: Investigative Ophthalmology and Visual Science. 62, 15, 27.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2019

Intraocular Oxygen and Antioxidant Status: New Insights on the Effect of Vitrectomy and Glaucoma Pathogenesis

Siegfried, C. J. & Shui, Y. B., Jul 2019, In: American journal of ophthalmology. 203, p. 12-25 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

2017

Effects of vitrectomy and lensectomy on older rhesus macaques: Oxygen distribution, antioxidant status, and aqueous humor dynamics

Siegfried, C. J., Shui, Y. B., Tian, B., Nork, T. M., Heatley, G. A. & Kaufman, P. L., Aug 2017, In: Investigative Ophthalmology and Visual Science. 58, 10, p. 4003-4014 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients

Ban, N., Siegfried, C. J., Lin, J. B., Shui, Y. B., Sein, J., Pita-Thomas, W., Sene, A., Santeford, A., Gordon, M., Lamb, R., Dong, Z., Kelly, S. C., Cavalli, V., Yoshino, J. & Apte, R. S., May 4 2017, In: JCI Insight. 2, 9, e91455.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

2016

Expression profiling of ascorbic acid-related transporters in human and mouse eyes

Ma, N., Siegfried, C., Kubota, M., Huang, J., Liu, Y., Liu, M., Dana, B., Huang, A., Beebe, D., Yan, H. & Shui, Y. B., Jun 2016, In: Investigative Ophthalmology and Visual Science. 57, 7, p. 3440-3450 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Mitochondrial oxygen metabolism in primary human lens epithelial cells: Association with age, diabetes and glaucoma

Kubota, M., Shui, Y. B., Liu, M., Bai, F., Huang, A. J., Ma, N., Beebe, D. C. & Siegfried, C. J., Aug 1 2016, In: Free Radical Biology and Medicine. 97, p. 513-519 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

2015

Central corneal thickness correlates with oxygen levels in the human anterior chamber angle

Siegfried, C. J., Shui, Y. B., Bai, F. & Beebe, D. C., Mar 1 2015, In: American journal of ophthalmology. 159, 3, p. 457-462.e1

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Impact of corneal endothelial dysfunctions on intraocular oxygen levels in human eyes

Huang, A. J. W., Shui, Y. B., Han, Y. P., Bai, F., Siegfried, C. J. & Beebe, D. C., Oct 2015, In: Investigative Ophthalmology and Visual Science. 56, 11, p. 6483-6488 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2014

Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucoma

Bennett, T. M., Mackay, D. S., Siegfried, C. J. & Shiels, A., Aug 4 2014, In: PloS one. 9, 8, e104000.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

Randomized, prospective, comparative trial of ex-press glaucoma filtration device versus trabeculectomy (XVT Study)

Netland, P. A., Sarkisian, S. R., Moster, M. R., Ahmed, I. I. K., Condon, G., Salim, S., Sherwood, M. B. & Siegfried, C. J., Feb 2014, In: American journal of ophthalmology. 157, 2, p. 433-440.e3

Research output: Contribution to journal › Article › peer-review

135 Scopus citations

2012

The development of a decision analytic model of changes in mean deviation in people with glaucoma: The COA model

Kymes, S. M., Lambert, D. L., Lee, P. P., Musch, D. C., Siegfried, C. J., Kotak, S. V., Stwalley, D. L., Fain, J., Johnson, C. & Gordon, M. O., Jul 2012, In: Ophthalmology. 119, 7, p. 1367-1374 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2011

Racial differences in ocular oxidative metabolism: Implications for ocular disease

Siegfried, C. J., Shui, Y. B., Holekamp, N. M., Bai, F. & Beebe, D. C., Jul 2011, In: Archives of Ophthalmology. 129, 7, p. 849-854 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

2010

Impact of laser trabeculoplasty on Trabectome® outcomes

Vold, S. D., Dustin, L., Compagna, Condon, Lauer, Budenz, Greenfield, Girkin, Francis, Ramirez, Al-Aswad, Smith, Donas, Asrani, Fellman, Godfrey, Mahan, Jones, Patitsas & Rabowsky & 68 others, Morgan, Rosenquist, Ghiasi, Yeh, Apte, Zhang, Tanji, Hangai, Rothstein, Briggs, Wiles, McKnight, Tamesis, Fanin, Brady, Rhee, Chen, Sit, Shetty, Bendel, Kayback, Amin, Sidoti, Laroche, Johnstone, Mills, Jamil, Osmundson, Marshall, Chevrier, Mitchell, Lloyd, Ceballos, Damji, Maeda, Miller, Sankar, Nguyen, Weinreb, Leen, Watanabe, Ichikawa, Reiss, Batiste, Moretsky, Cassidy, Zacharia, Stiles, Araie, Aihara, Baerveldt, Minckler, Mosaed, Kwon, Deokule, Schuman, Mitchell, Greenlee, Callender, Sulewski, Wang, Cotter, Barnett, Siegfried, Siepser, Friedman, Jampel & Trible, Jul 2010, In: Ophthalmic Surgery Lasers and Imaging. 41, 4, p. 443-451 9 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Oxygen distribution in the human eye: Relevance to the etiology of open-angle glaucoma after vitrectomy

Siegfried, C. J., Shui, Y. B., Holekamp, N. M., Bai, F. & Beebe, D. C., Nov 2010, In: Investigative Ophthalmology and Visual Science. 51, 11, p. 5731-5738 8 p.

Research output: Contribution to journal › Article › peer-review

133 Scopus citations

2009

The gel state of the vitreous and ascorbate-dependent oxygen consumption

Shui, Y. B., Holekamp, N. M., Kramer, B. C., Crowley, J. R., Wilkins, M. A., Chu, F., Malone, P. E., Mangers, S. J., Hou, J. H., Siegfried, C. J. & Beebe, D. C., Apr 2009, In: Archives of Ophthalmology. 127, 4, p. 475-482 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

162 Scopus citations

2008

The Impact of Anchor Point on Utilities for 5 Common Ophthalmic Diseases

Lee, B. S., Kymes, S. M., Nease, R. F., Sumner, W., Siegfried, C. J. & Gordon, M. O., May 2008, In: Ophthalmology. 115, 5, p. 898-903.e4

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Trabectome (trabeculectomy - internal approach): Additional experience and extended follow-up

Minckler, D., Mosaed, S., Dustin, L., Francis, B., Apte, D., Bandel, R. E., Shetty, R., Barnett, E. M., Batiste, C., Budenz, D., Chen, T., Rhee, D., Chevrier, R. L., Damji, K., Marshall, D., Compagna, J., Cotter, F., Donas, N., Fellman, R. & Friedman, D. & 31 others, Ghiasi, Z., Girkin, C., Godfrey, D., Jamil, A., Johnstone, M., Mills, R., Jones, L. S., Kwon, Y. H., Laroche, D., Leen, M., Maeda, M., Mahan, B. B., Mitchell, K., Nguyen, Q., Osmundson, G., Patitsas, C., Ramirez, M., Reiss, G., Rosenquist, R., Schuman, J., Sidoti, P., Siegfried, C. J., Sit, A., Stiles, M., Tamesis, R., Tanji, T., Trible, J., Vold, S. D., Watanabe, M., Weinreb, R. & Zacharia, P. T., 2008, In: Transactions of the American Ophthalmological Society. 106, p. 149-159 11 p.

Research output: Contribution to journal › Article › peer-review

174 Scopus citations

2006

Asymmetries and visual field summaries as predictors of glaucoma in the ocular hypertension treatment study

Levine, R. A., Demirel, S., Fan, J., Keltner, J. L., Johnson, C. A., Kass, M. A., Budenz, D. L., Fantes, F. E., Gedde, S. J., Parrish, R. K., Del Calvo, M. L., Harbin, T. S., McManus, P., Patorgis, C. J., Hooper, M. L., Goldstein, S. S., Lee, D. L., Morton, L., Perry, M. L. & Long, T. A. & 162 others, Smith, S. R., Wright, J. M., Gross, R. L., Orengo-Nania, S., Frady, P. M., Slight, B. D., Cioffi, G. A., Jamil, A. L., Mansberger, S., Patterson, E. L., Sherman, K., Fraser, J. A. M., Beck, A. D., Costarides, A., Hylton, C. M., Leef, D., Imami, N. R., Darnley-Fisch, D., Fantin, A., Gutkowski, M., Carnegie, E., Rock, S., Zack, D. J., Abrams, D. A., Congdon, N. G., Copeland, R. A., Friedman, D. S., Hemady, R., Higginbotham, E. J., Jampel, H. D., Pollack, I. P., Quigley, H. A., Robin, A. L., Scott, R., Keel, F., Levin, L., Powdrill, K. L., Priest-Reed, R., Coleman, A. L., Baker, R. S., Dang, Y. P., Giaconi, J. A. A., Law, S. K., Ballenberg, B., Murillo, S., Sharma, M., Bergstrom, T. J., Bruno, C. A., Moroi, S. E., Pollack-Rundle, C. J., Tehranisa, M. A., Hughes, B. A., Allen, M. Y., Juzych, M. S., McDermott, M. L., Ramocki, J. M., Allen, J., Schulz, L. L., O'Grady, J. M., Van Conett, L. A., Hall, M. B., Soltau, J. B., Mohay, J., Shrader, R. R., Lear, S., Herman, D. C., Johnson, D. H., Nielsen, B. A., Tvedt, N. J., Liebmann, J. M., Ritch, R., Tello, C. A., Walker, J. L., Mondoc, N. C., Simon, D. L., Weber, P., Baker, N. D., Derick, R. J., Lehmann, D., McKinney, K., Moore, D., Bennett, G. R., Yanoff, M., Bennett, L. C., Jameson, M., Piltz-Seymour, J. R., Ahmed, H. N., Miller, E. G., Sankar, P. S., McGill, C., Petner, J. T., Brandt, J. D., Casper, J. J., Lim, M. C., Schwab, I. R., Clark, I. J., Owensby, D. M., Sponzo, M. A., Weinreb, R. N., Slight, J. R., Okuonghae, O. A., Drake, M. V., Flach, A. J., Lin, S. C., Stamper, R., Ballesteros, F. P., Margol, V., Lamping, K. A., Vitelli, C. L., Modica, B. J., Gaasterland, D. E., Montgomery, R. L., Ashburn, F. S., Schacht, K. D., Schwartz, A. L., Weiss, H. S., Clark, C., Boeckl, A. M., Barnett, E. M., Becker, B., Bhorade, A. M., Kolker, A. E., Siegfried, C. J., Quirin, S., Darmody, F., Anderson, D. R., Everett, D. F., Gordon, M. E., Heuer, D. K., Keltner, J. A., Wilson, M. R., Morris, P. A., Roediger, T. A., Connett, J., Cowan, C., Davis, B., Katz, J. A., Munson, R., Sherwood, M., Skuta, G. L., Heur, D. K., Kymes, S., Miller, J. P., Bednarski, M., Beiser, J., Clark, K., Hornbeck, B., Long, E., Dunn, D., Wells-Albornoz, M. C., Vandenbroucke, R., Johnson, H., Feuer, W., Schiffman, J., Hess, D., Cello, K. E., Bandermann, S. E., Dhillon, B. S., Zangwill, L., Dirkes, K., Sample, P. A. & Bourne, W. M., Sep 2006, In: Investigative Ophthalmology and Visual Science. 47, 9, p. 3896-3903 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

1996

Endophthalmitis associated with a releasable suture

Rosenberg, L. F. & Siegfried, C. J., 1996, In: Archives of Ophthalmology. 114, 6, p. 767 1 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Marked intraocular pressure rise complicating intrableb autologous blood infection

Siegfried, C. J., Grewal, R. K., Karalekas, D., Rosenberg, L. F. & Krupin, T., Apr 1996, In: Archives of Ophthalmology. 114, 4, p. 492-493 2 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

1995

Apraclonidine and Anterior Segment Laser Surgery: Comparison of 0.5% versus 1.0% Apraclonidine for Prevention of Postoperative Intraocular Pressure Rise

Rosenberg, L. F., Krupin, T., Ruderman, J., McDaniel, D. L., Siegfried, C., Karalekas, D. P., Grewal, R. K., Gieser, D. K. & Williams, R., 1995, In: Ophthalmology. 102, 9, p. 1312-1318 7 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Hypotony after glaucoma filtration surgery: Mechanisms and incidence

Siegfried, C. J., Rosenberg, L. F., Krupin, T. & Jampol, L. M., Feb 1995, In: Journal of Glaucoma. 4, 1, p. 63-69 7 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

1994

Melanin can deplete immunosuppressive substances from the aqueous humor

Siegfried, C. J. & Hendricks, R. L., 1994, In: Current Eye Research. 13, 12, p. 869-873 5 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Melanin can deplete immunosuppressive substances from the aqueous humor

Siegfried, C. J. & Hendricks, R. L., Dec 1 1994, In: Regional Immunology. 6, 1-2, p. 85-89 5 p.

Research output: Contribution to journal › Article › peer-review

1990

Secondary bacterial peritonitis due to listeria monocytogenes after paracentesis

Siegfried, C. & Schubert, T. T., Feb 1990, In: Southern medical journal. 83, 2, p. 213-214 2 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Carla Siegfried

Research output

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