Carla Siegfried

2025

Celebrating the 40th Anniversary of the American Glaucoma Society: Yesterday, Today, and Tomorrow

Siegfried, C. J. & Skuta, G. L., Jan 1 2025, In: Ophthalmology. Glaucoma. 8, 1, p. 1-3 3 p.

Research output: Contribution to journal › Editorial

2024

SDPR expression in human trabecular meshwork and its potential role in racial disparities of glaucoma

Shui, Y. B., Liu, Y., Huang, A. J. W. & Siegfried, C. J., Dec 2024, In: Scientific reports. 14, 1, 10258.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Understanding racial disparities of glaucoma

Barquet-Pizá, V. & Siegfried, C. J., Mar 1 2024, In: Current Opinion in Ophthalmology. 35, 2, p. 97-103 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2022

Racial Disparities in Glaucoma: From Epidemiology to Pathophysiology

Siegfried, C. J. & Shui, Y. B., Jan 1 2022, In: Missouri Medicine. 119, 1, p. 49-54 6 p.

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

ROI, COI, and the Ethical Obligations of Journals

Van Gelder, R. N. & Siegfried, C. J., Jun 2022, In: Ophthalmology. 129, 6, p. 602-604 3 p.

Research output: Contribution to journal › Editorial

Open Access

1 Scopus citations

Trabecular Meshwork Mitochondrial Function and Oxidative Stress: Clues to Racial Disparities of Glaucoma

Wu, H., Shui, Y. B., Liu, Y., Liu, X. & Siegfried, C. J., Mar 2022, In: Ophthalmology Science. 2, 1, 100107.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

2021

Compositional Analysis of Extracellular Aggregates in the Eyes of Patients with Exfoliation Syndrome and Exfoliation Glaucoma

de Maria, A., Zientek, K. D., David, L. L., Wilmarth, P. A., Bhorade, A. M., Harocopos, G. J., Huang, A. J. W., Hong, A. R., Siegfried, C. J., Tsai, L. M., Sheybani, A. & Bassnett, S., Dec 2021, In: Investigative Ophthalmology and Visual Science. 62, 15, 27.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2020

Re: Bartley: Verifying surgical competence: our fiduciary responsibility (Ophthalmology. 2020;127:997–999)

Pelton, R. W. & Siegfried, C. J., Dec 2020, In: Ophthalmology. 127, 12, p. e111-e112

Research output: Contribution to journal › Letter › peer-review

Open Access

2019

Amaurosis fugax as the presenting symptom of metastatic lung adenocarcinoma

Li, H., J. Siegfried, C. & P. Van Stavern, G., Jun 2019, In: Canadian Journal of Ophthalmology. 54, 3, p. e131-e134

Research output: Contribution to journal › Letter › peer-review

Open Access

Intraocular Oxygen and Antioxidant Status: New Insights on the Effect of Vitrectomy and Glaucoma Pathogenesis

Siegfried, C. J. & Shui, Y. B., Jul 2019, In: American journal of ophthalmology. 203, p. 12-25 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

55 Scopus citations

Setting the Gold(en) Standard for Ethical Care: #PatientCommunication

Siegfried, C. J., Mar 2019, In: Ophthalmology. 126, 3, p. 335-337 3 p.

Research output: Contribution to journal › Editorial

2 Scopus citations

2018

Monitoring Neurodegeneration in Glaucoma: Therapeutic Implications

Ban, N., Siegfried, C. J. & Apte, R. S., Jan 2018, In: Trends in Molecular Medicine. 24, 1, p. 7-17 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

28 Scopus citations

2017

Effects of vitrectomy and lensectomy on older rhesus macaques: Oxygen distribution, antioxidant status, and aqueous humor dynamics

Siegfried, C. J., Shui, Y. B., Tian, B., Nork, T. M., Heatley, G. A. & Kaufman, P. L., Aug 2017, In: Investigative Ophthalmology and Visual Science. 58, 10, p. 4003-4014 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients

Ban, N., Siegfried, C. J., Lin, J. B., Shui, Y. B., Sein, J., Pita-Thomas, W., Sene, A., Santeford, A., Gordon, M., Lamb, R., Dong, Z., Kelly, S. C., Cavalli, V., Yoshino, J. & Apte, R. S., May 4 2017, In: JCI Insight. 2, 9, e91455.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

2016

Expression profiling of ascorbic acid-related transporters in human and mouse eyes

Ma, N., Siegfried, C., Kubota, M., Huang, J., Liu, Y., Liu, M., Dana, B., Huang, A., Beebe, D., Yan, H. & Shui, Y. B., Jun 2016, In: Investigative Ophthalmology and Visual Science. 57, 7, p. 3440-3450 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Mitochondrial oxygen metabolism in primary human lens epithelial cells: Association with age, diabetes and glaucoma

Kubota, M., Shui, Y. B., Liu, M., Bai, F., Huang, A. J., Ma, N., Beebe, D. C. & Siegfried, C. J., Aug 1 2016, In: Free Radical Biology and Medicine. 97, p. 513-519 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

2015

Central corneal thickness correlates with oxygen levels in the human anterior chamber angle

Siegfried, C. J., Shui, Y. B., Bai, F. & Beebe, D. C., Mar 1 2015, In: American journal of ophthalmology. 159, 3, p. 457-462.e1

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Impact of corneal endothelial dysfunctions on intraocular oxygen levels in human eyes

Huang, A. J. W., Shui, Y. B., Han, Y. P., Bai, F., Siegfried, C. J. & Beebe, D. C., Oct 2015, In: Investigative Ophthalmology and Visual Science. 56, 11, p. 6483-6488 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Reply

Siegfried, C. J., Shui, Y. B., Bai, F. & Beebe, D. C., Mar 1 2015, In: American journal of ophthalmology. 159, 3, p. 610-611 2 p.

Research output: Contribution to journal › Letter › peer-review

2014

Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucoma

Bennett, T. M., Mackay, D. S., Siegfried, C. J. & Shiels, A., Aug 4 2014, In: PloS one. 9, 8, e104000.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Preserve the (intraocular) environment: The importance of maintaining normal oxygen gradients in the eye

Beebe, D. C., Shui, Y. B., Siegfried, C. J., Holekamp, N. M. & Bai, F., May 2014, In: Japanese Journal of Ophthalmology. 58, 3, p. 225-231 7 p.

Research output: Contribution to journal › Review article › peer-review

71 Scopus citations

Randomized, prospective, comparative trial of ex-press glaucoma filtration device versus trabeculectomy (XVT Study)

Netland, P. A., Sarkisian, S. R., Moster, M. R., Ahmed, I. I. K., Condon, G., Salim, S., Sherwood, M. B. & Siegfried, C. J., Feb 2014, In: American journal of ophthalmology. 157, 2, p. 433-440.e3

Research output: Contribution to journal › Article › peer-review

137 Scopus citations

2013

Aqueous humor oxygen measurements

Nguyen, A., Shui, Y. B., Zhang, Q., Beebe, D. C. & Siegfried, C. J., Oct 2013, In: Journal of Glaucoma. 22, 8, p. e23-e24

Research output: Contribution to journal › Letter › peer-review

2 Scopus citations

2012

The development of a decision analytic model of changes in mean deviation in people with glaucoma: The COA model

Kymes, S. M., Lambert, D. L., Lee, P. P., Musch, D. C., Siegfried, C. J., Kotak, S. V., Stwalley, D. L., Fain, J., Johnson, C. & Gordon, M. O., Jul 2012, In: Ophthalmology. 119, 7, p. 1367-1374 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2011

Racial differences in ocular oxidative metabolism: Implications for ocular disease

Siegfried, C. J., Shui, Y. B., Holekamp, N. M., Bai, F. & Beebe, D. C., Jul 2011, In: Archives of Ophthalmology. 129, 7, p. 849-854 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Vitreoretinal influences on lens function and cataract

Beebe, D. C., Holekamp, N. M., Siegfried, C. & Shui, Y. B., Apr 27 2011, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 366, 1568, p. 1293-1300 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

81 Scopus citations

2010

Impact of laser trabeculoplasty on Trabectome® outcomes

Vold, S. D., Dustin, L., Compagna, Condon, Lauer, Budenz, Greenfield, Girkin, Francis, Ramirez, Al-Aswad, Smith, Donas, Asrani, Fellman, Godfrey, Mahan, Jones, Patitsas & Rabowsky & 68 others, Morgan, Rosenquist, Ghiasi, Yeh, Apte, Zhang, Tanji, Hangai, Rothstein, Briggs, Wiles, McKnight, Tamesis, Fanin, Brady, Rhee, Chen, Sit, Shetty, Bendel, Kayback, Amin, Sidoti, Laroche, Johnstone, Mills, Jamil, Osmundson, Marshall, Chevrier, Mitchell, Lloyd, Ceballos, Damji, Maeda, Miller, Sankar, Nguyen, Weinreb, Leen, Watanabe, Ichikawa, Reiss, Batiste, Moretsky, Cassidy, Zacharia, Stiles, Araie, Aihara, Baerveldt, Minckler, Mosaed, Kwon, Deokule, Schuman, Mitchell, Greenlee, Callender, Sulewski, Wang, Cotter, Barnett, Siegfried, Siepser, Friedman, Jampel & Trible, Jul 2010, In: Ophthalmic Surgery Lasers and Imaging. 41, 4, p. 443-451 9 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Oxygen distribution in the human eye: Relevance to the etiology of open-angle glaucoma after vitrectomy

Siegfried, C. J., Shui, Y. B., Holekamp, N. M., Bai, F. & Beebe, D. C., Nov 2010, In: Investigative Ophthalmology and Visual Science. 51, 11, p. 5731-5738 8 p.

Research output: Contribution to journal › Article › peer-review

133 Scopus citations

2009

The gel state of the vitreous and ascorbate-dependent oxygen consumption

Shui, Y. B., Holekamp, N. M., Kramer, B. C., Crowley, J. R., Wilkins, M. A., Chu, F., Malone, P. E., Mangers, S. J., Hou, J. H., Siegfried, C. J. & Beebe, D. C., Apr 2009, In: Archives of Ophthalmology. 127, 4, p. 475-482 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

164 Scopus citations

2008

The Impact of Anchor Point on Utilities for 5 Common Ophthalmic Diseases

Lee, B. S., Kymes, S. M., Nease, R. F., Sumner, W., Siegfried, C. J. & Gordon, M. O., May 2008, In: Ophthalmology. 115, 5, p. 898-903.e4

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Trabectome (trabeculectomy - internal approach): Additional experience and extended follow-up

Minckler, D., Mosaed, S., Dustin, L., Francis, B., Apte, D., Bandel, R. E., Shetty, R., Barnett, E. M., Batiste, C., Budenz, D., Chen, T., Rhee, D., Chevrier, R. L., Damji, K., Marshall, D., Compagna, J., Cotter, F., Donas, N., Fellman, R. & Friedman, D. & 31 others, Ghiasi, Z., Girkin, C., Godfrey, D., Jamil, A., Johnstone, M., Mills, R., Jones, L. S., Kwon, Y. H., Laroche, D., Leen, M., Maeda, M., Mahan, B. B., Mitchell, K., Nguyen, Q., Osmundson, G., Patitsas, C., Ramirez, M., Reiss, G., Rosenquist, R., Schuman, J., Sidoti, P., Siegfried, C. J., Sit, A., Stiles, M., Tamesis, R., Tanji, T., Trible, J., Vold, S. D., Watanabe, M., Weinreb, R. & Zacharia, P. T., 2008, In: Transactions of the American Ophthalmological Society. 106, p. 149-159 11 p.

Research output: Contribution to journal › Article › peer-review

177 Scopus citations

2006

Asymmetries and visual field summaries as predictors of glaucoma in the ocular hypertension treatment study

Levine, R. A., Demirel, S., Fan, J., Keltner, J. L., Johnson, C. A., Kass, M. A., Budenz, D. L., Fantes, F. E., Gedde, S. J., Parrish, R. K., Del Calvo, M. L., Harbin, T. S., McManus, P., Patorgis, C. J., Hooper, M. L., Goldstein, S. S., Lee, D. L., Morton, L., Perry, M. L. & Long, T. A. & 162 others, Smith, S. R., Wright, J. M., Gross, R. L., Orengo-Nania, S., Frady, P. M., Slight, B. D., Cioffi, G. A., Jamil, A. L., Mansberger, S., Patterson, E. L., Sherman, K., Fraser, J. A. M., Beck, A. D., Costarides, A., Hylton, C. M., Leef, D., Imami, N. R., Darnley-Fisch, D., Fantin, A., Gutkowski, M., Carnegie, E., Rock, S., Zack, D. J., Abrams, D. A., Congdon, N. G., Copeland, R. A., Friedman, D. S., Hemady, R., Higginbotham, E. J., Jampel, H. D., Pollack, I. P., Quigley, H. A., Robin, A. L., Scott, R., Keel, F., Levin, L., Powdrill, K. L., Priest-Reed, R., Coleman, A. L., Baker, R. S., Dang, Y. P., Giaconi, J. A. A., Law, S. K., Ballenberg, B., Murillo, S., Sharma, M., Bergstrom, T. J., Bruno, C. A., Moroi, S. E., Pollack-Rundle, C. J., Tehranisa, M. A., Hughes, B. A., Allen, M. Y., Juzych, M. S., McDermott, M. L., Ramocki, J. M., Allen, J., Schulz, L. L., O'Grady, J. M., Van Conett, L. A., Hall, M. B., Soltau, J. B., Mohay, J., Shrader, R. R., Lear, S., Herman, D. C., Johnson, D. H., Nielsen, B. A., Tvedt, N. J., Liebmann, J. M., Ritch, R., Tello, C. A., Walker, J. L., Mondoc, N. C., Simon, D. L., Weber, P., Baker, N. D., Derick, R. J., Lehmann, D., McKinney, K., Moore, D., Bennett, G. R., Yanoff, M., Bennett, L. C., Jameson, M., Piltz-Seymour, J. R., Ahmed, H. N., Miller, E. G., Sankar, P. S., McGill, C., Petner, J. T., Brandt, J. D., Casper, J. J., Lim, M. C., Schwab, I. R., Clark, I. J., Owensby, D. M., Sponzo, M. A., Weinreb, R. N., Slight, J. R., Okuonghae, O. A., Drake, M. V., Flach, A. J., Lin, S. C., Stamper, R., Ballesteros, F. P., Margol, V., Lamping, K. A., Vitelli, C. L., Modica, B. J., Gaasterland, D. E., Montgomery, R. L., Ashburn, F. S., Schacht, K. D., Schwartz, A. L., Weiss, H. S., Clark, C., Boeckl, A. M., Barnett, E. M., Becker, B., Bhorade, A. M., Kolker, A. E., Siegfried, C. J., Quirin, S., Darmody, F., Anderson, D. R., Everett, D. F., Gordon, M. E., Heuer, D. K., Keltner, J. A., Wilson, M. R., Morris, P. A., Roediger, T. A., Connett, J., Cowan, C., Davis, B., Katz, J. A., Munson, R., Sherwood, M., Skuta, G. L., Heur, D. K., Kymes, S., Miller, J. P., Bednarski, M., Beiser, J., Clark, K., Hornbeck, B., Long, E., Dunn, D., Wells-Albornoz, M. C., Vandenbroucke, R., Johnson, H., Feuer, W., Schiffman, J., Hess, D., Cello, K. E., Bandermann, S. E., Dhillon, B. S., Zangwill, L., Dirkes, K., Sample, P. A. & Bourne, W. M., Sep 2006, In: Investigative Ophthalmology and Visual Science. 47, 9, p. 3896-3903 8 p.

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

1997

Endophthalmitis Associated With Releasable Sutures-Reply

Burchfield, J. C., Kolker, A. E., Siegfried, C. J., Cook, S. G. & Rosenberg, L. F., Feb 1997, In: Archives of Ophthalmology. 115, 2, p. 292 1 p.

Research output: Contribution to journal › Letter › peer-review

1996

Endophthalmitis associated with a releasable suture

Rosenberg, L. F. & Siegfried, C. J., 1996, In: Archives of Ophthalmology. 114, 6, p. 767 1 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Marked intraocular pressure rise complicating intrableb autologous blood infection

Siegfried, C. J., Grewal, R. K., Karalekas, D., Rosenberg, L. F. & Krupin, T., Apr 1996, In: Archives of Ophthalmology. 114, 4, p. 492-493 2 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

1995

Apraclonidine and Anterior Segment Laser Surgery: Comparison of 0.5% versus 1.0% Apraclonidine for Prevention of Postoperative Intraocular Pressure Rise

Rosenberg, L. F., Krupin, T., Ruderman, J., McDaniel, D. L., Siegfried, C., Karalekas, D. P., Grewal, R. K., Gieser, D. K. & Williams, R., 1995, In: Ophthalmology. 102, 9, p. 1312-1318 7 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Hypotony after glaucoma filtration surgery: Mechanisms and incidence

Siegfried, C. J., Rosenberg, L. F., Krupin, T. & Jampol, L. M., Feb 1995, In: Journal of Glaucoma. 4, 1, p. 63-69 7 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

1994

Melanin can deplete immunosuppressive substances from the aqueous humor

Siegfried, C. J. & Hendricks, R. L., Dec 1 1994, In: Regional Immunology. 6, 1-2, p. 85-89 5 p.

Research output: Contribution to journal › Article › peer-review

Melanin can deplete immunosuppressive substances from the aqueous humor

Siegfried, C. J. & Hendricks, R. L., 1994, In: Current Eye Research. 13, 12, p. 869-873 5 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

1990

Secondary bacterial peritonitis due to listeria monocytogenes after paracentesis

Siegfried, C. & Schubert, T. T., Feb 1990, In: Southern medical journal. 83, 2, p. 213-214 2 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Carla Siegfried

Research output

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