• 929 Citations
20062020

Research output per year

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Personal profile

Research interests

Dr. Rosa’s research is focused on the bioinformatic analysis of high-throughput omics datasets. His research has focused on the study of parasitic helminths, which infect almost a third of the world’s population (primarily in tropical regions) and cause widespread disease, disability and even death. Through the analysis of omics data, he has contributed to studies on a range of parasitic nematodes and trematodes, including comprehensive studies spanning the phyla, identifying novel drug targets and drugs, analyzing molecular pathways associated with host interactions and anthelmintic responses, and other types of statistical analyses. All of this work will contribute to the broader goals of identifying more effective treatment and prevention strategies. In addition to his parasitic helminth work, Dr. Rosa is involved in collaborative projects studying conserved host immune responses to tuberculosis (spanning humans, macaques and mice), human immune responses to malaria before and after treatment, and strain differences during HIV infection.

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Research Output

Comparative genomics and transcriptomics of 4 Paragonimus species provide insights into lung fluke parasitism and pathogenesis

Rosa, B. A., Choi, Y. J., McNulty, S. N., Jung, H., Martin, J., Agatsuma, T., Sugiyama, H., Le, T. H., Doanh, P. N., Maleewong, W., Blair, D., Brindley, P. J., Fischer, P. U. & Mitreva, M., Jul 1 2020, In : GigaScience. 9, 7

Research output: Contribution to journalArticle

Open Access
  • De novo identification of toxicants that cause irreparable damage to parasitic nematode intestinal cells

    Jasmer, D. P., Rosa, B. A., Tyagi, R., Bulman, C. A., Beerntsen, B., Urban, J. F., Sakanari, J. & Mitreva, M., May 2020, In : PLoS neglected tropical diseases. 14, 5, p. 1-33 33 p., e0007942.

    Research output: Contribution to journalArticle

    Open Access
  • Immune correlates of tuberculosis disease and risk translate across species

    Ahmed, M., Thirunavukkarasu, S., Rosa, B. A., Thomas, K. A., Das, S., Rangel-Moreno, J., Lu, L., Mehra, S., Mbandi, S. K., Thackray, L. B., Diamond, M. S., Murphy, K. M., Means, T., Martin, J., Kaushal, D., Scriba, T. J., Mitreva, M. & Khader, S. A., Jan 29 2020, In : Science translational medicine. 12, 528, eaay0233.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Improving characterization of understudied human microbiomes using targeted phylogenetics

    Rosa, B. A., Mihindukulasuriya, K., Hallsworth-Pepin, K., Wollam, A., Martin, J., Snowden, C., Dunne, W. M., Weinstock, G. M., Burnham, C. A. D. & Mitreva, M., 2020, In : mSystems. 5, 1, e00096.

    Research output: Contribution to journalArticle

    Open Access
  • Mycobacterium tuberculosis HN878 Infection Induces Human-Like B-Cell Follicles in Mice

    Choreño-Parra, J. A., Bobba, S., Rangel-Moreno, J., Ahmed, M., Mehra, S., Rosa, B., Martin, J., Mitreva, M., Kaushal, D., Zúñiga, J. & Khader, S. A., Apr 27 2020, In : Journal of Infectious Diseases. 221, 10, p. 1636-1646 11 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations