Our laboratory is interested in the intersection between cellular metabolism and epigenetics, and how transcription factors mediate changes to these processes during cellular differentiation. Our lab has particular interest in the metabolism of lymphatic endothelial cells, and how metabolic pathways can regulate lymphangiogenesis and lymphatic function. We are currently investigating the role of lymphatics and lymphangiogenesis in multiple solid organ transplant models (heart, lung, kidney), with particular emphasis on interactions between the immune system, lymphatic vessels and the lymphoid system.