The Muegge Lab is interested in the genetic and metabolic regulation of cell fate decisions. We are especially focused on defining how epithelial stem cells in the gut give rise to the diverse intestinal endocrine system, with the goal of discovering novel ways to treat metabolic diseases using gut hormones. We use cutting edge bulk and single-cell RNA-seq and epigenetic methods. Our work is at the interface of computational genomics, developmental biology, and cellular models of disease. We invite applications from enthusiastic scientists of any disciplinary background interested in joining our collaborative team. Please see our website for additional details on current research projects and team members. 

• Lab Website

My greatest responsibility as a PI is to train the next generation of scientists and physician-scientists and to empower them to take the next step on their career journeys. Scientific training is a springboard to many different career paths, and I will actively support you in whatever career path fits your goals. Training in our lab emphasizes transferable skills in experimental design, data analysis, communication, and critical thinking that are foundational to many possible careers.

I have taken the #MentorFirst Pledge, because I believe that the best scientific research will only happen when all the members of our team feel supported and have the mentoring and advice they need to be successful.