Brian Dieckgraefe

2022

Colonoscopy Following COVID-19 Delays in Procedures: Risk Stratification for Procedures Is Critical

Fritz, C. D. L., Sayuk, G. S., Elwing, J. E., Wilgus, N. C., Dieckgraefe, B. K. & Presti, M. E., Jan 2022, In: Gastro Hep Advances. 1, 4, p. 546-548 3 p.

Research output: Contribution to journal › Short survey › peer-review

Open Access

2 Scopus citations

Editor’s Note: Diphenyl Difluoroketone: A Curcumin Derivative with Potent in Vivo Anticancer Activity

Subramaniam, D., May, R., Sureban, S. M., Lee, K. B., George, R., Kuppusamy, P., Ramanujam, R. P., Hideg, K., Dieckgraefe, B. K., Houchen, C. W. & Anant, S., Aug 15 2022, In: Cancer research. 82, 16, p. 2951 1 p.

Research output: Contribution to journal › Editorial

Open Access

1 Scopus citations

Reg4 Interacts with CD44 to Regulate Proliferation and Stemness of Colorectal and Pancreatic Cancer Cells

Bishnupuri, K. S., Sainathan, S. K., Ciorba, M. A., Houchen, C. W. & Dieckgraefe, B. K., Mar 2022, In: Molecular Cancer Research. 20, 3, p. 387-399 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

2021

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer

Sninsky, J. A., Bishnupuri, K. S., González, I., Trikalinos, N. A., Chen, L. & Dieckgraefe, B. K., Feb 16 2021, In: Oncotarget. 12, 4, p. 278-291 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2020

Quality metrics of screening colonoscopies performed by PAs

Fejleh, M. P., Shen, C. C., Chen, J., Bushong, J. A., Dieckgraefe, B. K. & Sayuk, G. S., Apr 1 2020, In: JAAPA : official journal of the American Academy of Physician Assistants. 33, 4, p. 43-48 6 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2019

IDO1 and kynurenine pathway metabolites activate PI3K-Akt signaling in the neoplastic colon epithelium to promote cancer cell proliferation and inhibit apoptosis

Bishnupuri, K. S., Alvarado, D. M., Khouri, A. N., Shabsovich, M., Chen, B., Dieckgraefe, B. K. & Ciorba, M. A., 2019, In: Cancer research. 79, 6, p. 1138-1150 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

158 Scopus citations

Insulinoma-associated protein 1 expression in primary and metastatic neuroendocrine neoplasms of the gastrointestinal and pancreaticobiliary tracts

González, I., Lu, H. C., Sninsky, J., Yang, C., Bishnupuri, K., Dieckgraefe, B., Cao, D. & Chatterjee, D., Oct 1 2019, In: Histopathology. 75, 4, p. 568-577 10 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

2018

A Randomized Trial of Off-Site Collaborative Care for Depression in Chronic Hepatitis C Virus

Kanwal, F., Pyne, J. M., Tavakoli-Tabasi, S., Nicholson, S., Dieckgraefe, B., Storay, E., Goetz, M. B., Kramer, J. R., Smith, D., Sansgiry, S., Tansel, A., Gifford, A. L. & Asch, S. M., Aug 2018, In: Health services research. 53, 4, p. 2547-2566 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2016

Collaborative care for depression in chronic hepatitis C clinics

Kanwal, F., Pyne, J. M., Tavakoli-Tabasi, S., Nicholson, S., Dieckgraefe, B., Storay, E., Goetz, M. B., Smith, D. L., Sansgiry, S., Gifford, A. & Asch, S. M., Oct 1 2016, In: Psychiatric Services. 67, 10, p. 1076-1082 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2014

Reg4-induced mitogenesis involves Akt-GSK3β-β-Catenin-TCF-4 signaling in human colorectal cancer

Bishnupuri, K. S., Sainathan, S. K., Bishnupuri, K., Leahy, D. R., Luo, Q., Anant, S., Houchen, C. W. & Dieckgraefe, B. K., 2014, In: Molecular Carcinogenesis. 53, S1, p. E169-E180

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

2012

Dextran sodium sulfate inhibition of real-time polymerase chain reaction amplification: A poly-A purification solution

Kerr, T. A., Ciorba, M. A., Matsumoto, H., Davis, V. R. T., Luo, J., Kennedy, S., Xie, Y., Shaker, A., Dieckgraefe, B. K. & Davidson, N. O., Feb 2012, In: Inflammatory bowel diseases. 18, 2, p. 344-348 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Toll-like receptor-7 ligand imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis

Sainathan, S. K., Bishnupuri, K. S., Aden, K., Luo, Q., Houchen, C. W., Anant, S. & Dieckgraefe, B. K., May 2012, In: Inflammatory bowel diseases. 18, 5, p. 955-967 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

2011

RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells

Subramaniam, D., Ramalingam, S., Linehan, D. C., Dieckgraefe, B. K., Postier, R. G., Houchen, C. W., Jensen, R. A. & Anant, S., 2011, In: PloS one. 6, 2, e16958.

Research output: Contribution to journal › Article › peer-review

Open Access

62 Scopus citations

2010

Clostridium difficile-associated disease in allogeneic hematopoietic stem-cell transplant recipients: Risk associations, protective associations, and outcomes

Dubberke, E. R., Reske, K. A., Srivastava, A., Sadhu, J., Gatti, R., Young, R. M., Rakes, L. C., Dieckgraefe, B., DiPersio, J. & Fraser, V. J., Mar 2010, In: Clinical Transplantation. 24, 2, p. 192-198 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

Dendritic cells produce CXCL13 and participate in the development of murine small intestine lymphoid tissues

McDonald, K. G., McDonough, J. S., Dieckgraefe, B. K. & Newberry, R. D., May 2010, In: American Journal of Pathology. 176, 5, p. 2367-2377 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

NOD2 status and human ileal gene expression

Hamm, C. M., Reimers, M. A., McCullough, C. K., Gorbe, E. B., Lu, J., Gu, C. C., Li, E., Dieckgraefe, B. K., Gong, Q., Stappenbeck, T. S., Stone, C. D., Dietz, D. W. & Hunt, S. R., Oct 2010, In: Inflammatory bowel diseases. 16, 10, p. 1649-1657 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Reg IV Regulates Normal Intestinal and Colorectal Cancer Cell Susceptibility to Radiation-Induced Apoptosis

Bishnupuri, K. S., Luo, Q., Sainathan, S. K., Kikuchi, K., Sureban, S. M., Sabarinathan, M., Gross, J. H., Aden, K., May, R., Houchen, C. W., Anant, S. & Dieckgraefe, B. K., Feb 2010, In: Gastroenterology. 138, 2, p. 616-626.e2

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

2009

Loss of p21 ^{Waf1/Cip1/Sdl1} enhances intestinal stem cell survival following radiation injury

George, R. J., Sturmoski, M. A., May, R., Sureban, S. M., Dieckgraefe, B. K., Anant, S. & Houchen, C. W., Feb 2009, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 296, 2, p. G245-G254

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

2008

Diphenyl difluoroketone: A curcumin derivative with potent in vivo anticancer activity

Subramaniam, D., May, R., Sureban, S. M., Lee, K. B., George, R., Kuppusamy, P., Ramanujam, R. P., Hideg, K., Dieckgraefe, B. K., Houchen, C. W. & Anant, S., Mar 15 2008, In: Cancer research. 68, 6, p. 1962-1969 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

150 Scopus citations

Gastrin-Mediated Interleukin-8 and Cyclooxygenase-2 Gene Expression: Differential Transcriptional and Posttranscriptional Mechanisms

Subramaniam, D., Ramalingam, S., May, R., Dieckgraefe, B. K., Berg, D. E., Pothoulakis, C., Houchen, C. W., Wang, T. C. & Anant, S., Apr 2008, In: Gastroenterology. 134, 4, p. 1070-1082 13 p.

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis

Sainathan, S. K., Hanna, E. M., Gong, Q., Bishnupuri, K. S., Luo, Q., Colonna, M., White, F. V., Croze, E., Houchen, C., Anant, S. & Dieckgraefe, B. K., Jan 2008, In: Inflammatory bowel diseases. 14, 1, p. 88-99 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

114 Scopus citations

Knockdown of RNA Binding Protein Musashi-1 Leads to Tumor Regression In Vivo

Sureban, S. M., May, R., George, R. J., Dieckgraefe, B. K., McLeod, H. L., Ramalingam, S., Bishnupuri, K. S., Natarajan, G., Anant, S. & Houchen, C. W., May 2008, In: Gastroenterology. 134, 5, p. 1448-1458.e2

Research output: Contribution to journal › Article › peer-review

154 Scopus citations

REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis

Astrosini, C., Roeefzaad, C., Dai, Y. Y., Dieckgraefe, B. K., Jöns, T. & Kemmner, W., Jul 15 2008, In: International Journal of Cancer. 123, 2, p. 409-413 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe

Sureban, S. M., Ramalingam, S., Natarajan, G., May, R., Subramaniam, D., Bishnupuri, K. S., Morrison, A. R., Dieckgraefe, B. K., Brackett, D. J., Postier, R. G., Houchen, C. W. & Anant, S., Jul 31 2008, In: Oncogene. 27, 33, p. 4544-4556 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

118 Scopus citations

2007

Characterization of cecal gene expression in a differentially susceptible mouse model of bacterial-induced inflammatory bowel disease

Myles, M. H., Dieckgraefe, B. K., Criley, J. M. & Franklin, C. L., Jul 2007, In: Inflammatory bowel diseases. 13, 7, p. 822-836 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Expression of the genes dual oxidase 2, lipocalin 2 and regenerating islet-derived 1 alpha in Crohn's disease

Csillag, C., Nielsen, O. H., Vainer, B., Olsen, J., Dieckgraefe, B. K., Hendel, J., Vind, I., Dupuy, C., Nielsen, F. C. & Borup, R., 2007, In: Scandinavian Journal of Gastroenterology. 42, 4, p. 454-463 10 p.

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Functional Antagonism Between RNA Binding Proteins HuR and CUGBP2 Determines the Fate of COX-2 mRNA Translation

Sureban, S. M., Murmu, N., Rodriguez, P., May, R., Maheshwari, R., Dieckgraefe, B. K., Houchen, C. W. & Anant, S., Mar 2007, In: Gastroenterology. 132, 3, p. 1055-1065 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

66 Scopus citations

2006

Azoxymethane protects intestinal stem cells and reduces crypt epithelial mitosis through a COX-1-dependent mechanism

Riehl, T. E., George, R. J., Sturmoski, M. A., May, R., Dieckgraefe, B., Anant, S. & Houchen, C. W., Dec 2006, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 291, 6, p. G1062-G1070

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes

Bishnupuri, K. S., Luo, Q., Korzenik, J. R., Henderson, J. O., Houchen, C. W., Anant, S. & Dieckgraefe, B. K., Dec 2006, In: Cancer Biology and Therapy. 5, 12, p. 1714-1720 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Growth factors as treatment options for intestinal inflammation

Dieckgraefe, B. K., Korzenik, J. R. & Anant, S., 2006, Inflammatory Bowel Disease: Genetics, Barrier Function, Immunologic Mechanisms, and Microbial Pathways. Blackwell Publishing Inc., p. 300-306 7 p. (Annals of the New York Academy of Sciences; vol. 1072).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

22 Scopus citations

Molecular biology of the small intestine

Ahuja, V., Dieckgraefe, B. K. & Anant, S., Mar 2006, In: Current opinion in gastroenterology. 22, 2, p. 90-94 5 p.

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Pancreatic regenerating protein (reg I) and reg I receptor mRNA are upregulated in rat pancreas after induction of acute panceatitis

Bluth, M. H., Patel, S. A., Dieckgraefe, B. K., Okamoto, H. & Zenilman, M. E., Jul 28 2006, In: World Journal of Gastroenterology. 12, 28, p. 4511-4516 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas

Bishnupuri, K. S., Luo, Q., Murmu, N., Houchen, C. W., Anant, S. & Dieckgraefe, B. K., Jan 2006, In: Gastroenterology. 130, 1, p. 137-149 13 p.

Research output: Contribution to journal › Article › peer-review

123 Scopus citations

2005

An open-labelled study of granulocyte colony-stimulating factor in the treatment of active Crohn's disease

Korzenik, J. R. & Dieckgraefe, B. K., Feb 15 2005, In: Alimentary Pharmacology and Therapeutics. 21, 4, p. 391-400 10 p.

Research output: Contribution to journal › Article › peer-review

86 Scopus citations

PEGylated murine Granulocyte-macrophage colony-stimulating factor: Production, purification, and characterization

Sainathan, S. K., Tu, L., Bishnupuri, K. S., Han, M., Li, A., Newberry, R. D., McDonald, K. G., Crimmins, D. L., Houchen, C., Anant, S. & Dieckgraefe, B. K., Dec 2005, In: Protein Expression and Purification. 44, 2, p. 94-103 10 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Sargramostim for active Crohn's disease

Korzenik, J. R., Dieckgraefe, B. K., Valentine, J. F., Hausman, D. F. & Gilbert, M. J., May 26 2005, In: New England Journal of Medicine. 352, 21, p. 2193-2201 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

317 Scopus citations

What does football have in common with Crohn's disease? The best "defense-in" is a good offense.

Dieckgraefe, B. K., Mar 2005, In: Inflammatory bowel diseases. 11, 3, p. 322-323 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2004

Delayed hepatocellular mitotic progression and impaired liver regeneration in early growth response-1-deficient mice

Liao, Y., Shikapwashya, O. N., Shteyer, E., Dieckgraefe, B. K., Hruz, P. W. & Rudnick, D. A., Oct 8 2004, In: Journal of Biological Chemistry. 279, 41, p. 43107-43116 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

91 Scopus citations

Dynamic antagonism between RNA-binding protein CUGBP2 and cyclooxygenase-2-mediated prostaglandin E₂ in radiation damage

Murmu, N., Jung, J., Mukhopadhyay, D., Houchen, C. W., Riehl, T. E., Stenson, W. F., Morrison, A. R., Arumugam, T., Dieckgraefe, B. K. & Anant, S., Sep 21 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 38, p. 13873-13878 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2003

Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2

Mukhopadhyay, D., Houchen, C. W., Kennedy, S., Dieckgraefe, B. K. & Anant, S., Jan 1 2003, In: Molecular cell. 11, 1, p. 113-126 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

193 Scopus citations

CUGBP2 Plays a Critical Role in Apoptosis of Breast Cancer Cells in Response to Genotoxic Injury

Mukhopadhyay, D., Jung, J., Murmu, N., Houchen, C. W., Dieckgraefe, B. K. & Anant, S., 2003, In: Annals of the New York Academy of Sciences. 1010, p. 504-509 6 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Expression of a novel regenerating gene product, Reg IV, by high density fermentation in Pichia pastoris: Production, purification, and characterization

Li, A., Crimmins, D. L., Luo, Q., Hartupee, J., Landt, Y., Ladenson, J. H., Wilson, D., Anant, S. & Dieckgraefe, B. K., Oct 2003, In: Protein Expression and Purification. 31, 2, p. 197-206 10 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Granulocyte-macrophage colony-stimulating factor for Crohn's disease [7] (multiple letters)

Drumm, B., Vaughan, D., Dieckgraefe, B. K. & Korzenik, J. R., May 24 2003, In: Lancet. 361, 9371, p. 1830-1831 2 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

2002

Application of genome-wide gene expression profiling by high-density DNA arrays to the treatment and study of inflammatory bowel disease

Warner, E. E. & Dieckgraefe, B. K., 2002, In: Inflammatory bowel diseases. 8, 2, p. 140-157 18 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Association of glycogen storage disease 1b and Crohn disease: Results of a North American survey

Dieckgraefe, B. K., Korzenik, J. R., Husain, A. & Dieruf, L., Oct 16 2002, In: European Journal of Pediatrics, Supplement. 161, 1, p. S88-S92

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

Expression of the regenerating gene family in inflammatory bowel disease mucosa: Reg Iα upregulation, processing, and antiapoptotic activity

Dieckgraefe, B. K., Crimmins, D. L., Landt, V., Houchen, C., Anant, S., Porche-Sorbet, R. & Ladenson, J. H., Nov 2002, In: Journal of Investigative Medicine. 50, 6, p. 421-434 14 p.

Research output: Contribution to journal › Article › peer-review

86 Scopus citations

Isolation and characterization of rabbit single chain antibodies to human Reg Iα protein

Chi, X. S., Landt, Y., Crimmins, D. L., Dieckgraefe, B. K. & Ladenson, J. H., Aug 1 2002, In: Journal of Immunological Methods. 266, 1-2, p. 197-207 11 p.

Research output: Contribution to journal › Article › peer-review