Research output per year
Research output per year
Personal profile
Research interests
Our lab employs cutting-edge molecular biology techniques to investigate the genetic, epigenetic, and cellular alterations driving the initiation, progression, and therapeutic resistance of skull base brain tumors. By elucidating the molecular pathways involved, we aim to identify novel biomarkers for early detection, prognostication, and personalized treatment strategies.
Clinical interests
Brain metastases, Chordoma, chondrosarcoma and other clival tumors, Chondrosarcoma, Craniofacial and sinonasal tumors, Glioblastomas and other gliomas, Hydrocephalus, Meningiomas, Skull base and pituitary tumors, Vestibular schwannomas
Available to Mentor:
- PhD/MSTP Students
- Health Professions Students
- Postdocs
- Residents and Fellows
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Collaborations and top research areas from the last five years
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Spatially resolved transcriptomics and graph-based deep learning improve accuracy of routine CNS tumor diagnostics
Ritter, M., Blume, C., Tang, Y., Patel, A., Patel, B., Berghaus, N., Kada Benotmane, J., Kueckelhaus, J., Yabo, Y., Zhang, J., Grabis, E., Villa, G., Zimmer, D. N., Khriesh, A., Sievers, P., Seferbekova, Z., Hinz, F., Ravi, V. M., Seiz-Rosenhagen, M. & Ratliff, M. & 8 others, , Feb 2025, In: Nature Cancer. 6, 2, p. 292-306 15 p., 4122.Research output: Contribution to journal › Article › peer-review
Open Access -
Anterolateral keyhole transorbital routes to the skull base: a comparative anatomical study
Karampouga, M., Terrarosa, A. K., Patel, B., Affolter, K., Wang, E. W., Choby, G. W., Fu, R., Bonhomme, G. R., Stefko, S. T., McDowell, M. M., Snyderman, C. H., Gardner, P. A. & Zenonos, G. A., 2024, In: Neurosurgical focus. 56, 4, E3.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Multiomic and clinical analysis of multiply recurrent meningiomas reveals risk factors, underlying biology, and insights into evolution
Pugazenthi, S., Patel, B., English, C. W., Leidig, W. A., McGeehan, K. P., McCornack, C. R., Mok, S., Anzaldua-Campos, M., Nouri, S. H., Roberts, K., Chatrath, A., Khan, A. B., Gadot, R., Yano, H., Klisch, T. J., Harmanci, A. S., Patel, A. J. & Kim, A. H., Oct 25 2024, In: Science Advances. 10, 43, eadn4419.Research output: Contribution to journal › Article › peer-review
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Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state
Barrett, T. F., Patel, B., Khan, S. M., Mullins, R. D. Z., Yim, A. K. Y., Pugazenthi, S., Mahlokozera, T., Zipfel, G. J., Herzog, J. A., Chicoine, M. R., Wick, C. C., Durakovic, N., Osbun, J. W., Shew, M., Sweeney, A. D., Patel, A. J., Buchman, C. A., Petti, A. A., Puram, S. V. & Kim, A. H., Dec 2024, In: Nature communications. 15, 1, 478.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Comparative cost analysis of endovascular and open approaches for elective treatment of middle cerebral artery aneurysms
Lauzier, D. C., Cler, S. J., Srienc, A. I., Patel, B., Pierce, A., Gagne, J., Vellimana, A. K., Chatterjee, R., Kansagra, A., Moran, C., Zipfel, G. J. & Osbun, J. W., 2023, (Accepted/In press) In: Interventional Neuroradiology.Research output: Contribution to journal › Article › peer-review