Ben Major

Professor of Cell Biology and Physiology, Professor of Otolaryngology, Alan A and Edith L Wolff Distinguished Professor

    • 3031 Citations

    Research output per year

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    Research Output

    A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue

    Bowman, B. M., Montgomery, S. A., Schrank, T. P., Simon, J. M., Ptacek, T. S., Tamir, T. Y., Mulvaney, K. M., Weir, S. J., Nguyen, T. T., Murphy, R. M., Makowski, L., Hayes, D. N., Chen, X. L., Randell, S. H., Weissman, B. E. & Major, M. B., Oct 1 2020, In : Journal of Pathology. 252, 2, p. 125-137 13 p.

    Research output: Contribution to journalArticle

  • Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding

    Skrajna, A., Goldfarb, D., Kedziora, K. M., Cousins, E. M., Grant, G. D., Spangler, C. J., Barbour, E. H., Yan, X., Hathaway, N. A., Brown, N. G., Cook, J. G., Major, M. B. & McGinty, R. K., Sep 25 2020, In : Nucleic acids research. 48, 17, p. 9415-9432 18 p.

    Research output: Contribution to journalArticle

    Open Access
  • Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor

    Tamir, T. Y., Bowman, B. M., Agajanian, M. J., Goldfarb, D., Schrank, T. P., Stohrer, T., Hale, A. E., Siesser, P. F., Weir, S. J., Murphy, R. M., LaPak, K. M., Weissman, B. E., Moorman, N. J. & Major, M. B., Jul 15 2020, In : Journal of cell science. 133, 14

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor

    Tamir, T. Y., Drewry, D. H., Wells, C., Major, M. B. & Axtman, A. D., Dec 1 2020, In : Scientific reports. 10, 1, 15826.

    Research output: Contribution to journalArticle

    Open Access
  • PPP6C negatively regulates sting-dependent innate immune responses

    Ni, G., Ma, Z., Wong, J. P., Zhang, Z., Cousins, E., Major, M. B. & Damania, B., Jul 1 2020, In : mBio. 11, 4, p. 1-13 13 p., e01728-20.

    Research output: Contribution to journalArticle

    Open Access